| Interacting proteins: Q9UIS9 and Q15047 |
Pubmed |
SVM Score :0.6748545 |
| Here we show that MBD 1 containing chromatin associated factor ( MCAF ) 1 , also known as the human homologue of murine ATFa associated modulator ( AM ) , is required for transcriptional repression and heterochromatin formation by MBD 1 , together with the involvement of SETDB 1 . 0.6748545^^^ |
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| Interacting proteins: Q9UIS9 and Q15047 |
Pubmed |
SVM Score :0.0 |
| Methyl CpG binding protein MBD 1 couples histone H 3 methylation at lysine 9 by SETDB 1 to DNA replication and chromatin assembly . ^^^ Here we show that the methyl CpG binding protein MBD 1 forms a stable complex with histone H 3 K9 methylase SETDB 1 . ^^^ |
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| Interacting proteins: Q9UIS9 and Q15047 |
Pubmed |
SVM Score :0.0 |
| Here we demonstrate that SUMOs directly interact with human MCAF 1 , which forms complexes with either the methyl CpG binding protein MBD 1 or SETDB 1 , which trimethylates histone H 3 at lysine 9 ( H 3 K9 ) in the presence of MCAF 1 . ^^^ |
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