| Interacting proteins: Q9NYB9 and P00519 |
Pubmed |
SVM Score :0.8150805 |
| Abi 2 binds to c Abl in vitro and in vivo . 0.8150805^^^ The cDNA encoding the Abl interactor protein ( Abi 2 ) , was isolated from a human lymphocyte library using the yeast two hybrid system with the Abl SH 3 domain as bait . 0.5080898^^^ |
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| Interacting proteins: Q9NYB9 and P00519 |
Pubmed |
SVM Score :0.0 |
| The deduced amino acid sequence revealed that THR protein ( THRP ) , a 68 kDa moiety , has 83 % sequence similarity with c Abl interactor protein ( Abi 2 ) , which is a substrate for tyrosine kinase activity of c Abl . ^^^ |
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| Interacting proteins: Q9NYB9 and P00519 |
Pubmed |
SVM Score :0.0 |
| Localization and phosphorylation of Abl interactor proteins , Abi 1 and Abi 2 , in the developing nervous system . ^^^ We asked if the expression , phosphorylation , and cellular localization of Abi 1 and Abi 2 supports a role for these proteins in Abl signaling in the developing and adult mouse nervous system . ^^^ |
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| Interacting proteins: Q9NYB9 and P00519 |
Pubmed |
SVM Score :0.0 |
| The thyroid hormone responsive protein ( THRP ) is expressed in rat cerebral tissue and has 83 % overall sequence homology with c Abl interactor protein , Abi 2 , which is a substrate for the tyrosine kinase activity of c Abl . ^^^ |
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| Interacting proteins: Q9NYB9 and P00519 |
Pubmed |
SVM Score :0.0 |
| BACKGROUND : Abelson ( Abl ) interactor 2 ( Abi 2 ) has been considered as a key regulator of cell / tissue structural organization and is differentially expressed in leiomyomas . ^^^ |
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| Interacting proteins: Q9NYB9 and P00519 |
Pubmed |
SVM Score :0.0 |
| Deletion of the Src homology 3 domain and C terminal proline rich sequences in Bcr Abl prevents Abl interactor 2 degradation and spontaneous cell migration and impairs leukemogenesis . ^^^ We report here that the Src homology 3 domain and C terminal proline rich sequences of Bcr Abl are required for its binding to Abl interactor 2 as well as for the induction of Abl interactor 2 degradation . ^^^ Furthermore , the mutant Bcr Abl , defective in binding to Abl interactor 2 and inducing its degradation , failed to induce chronic myelogenous leukemia like disease in mouse . ^^^ |
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| Interacting proteins: Q9NYB9 and P00519 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q9NYB9 and P00519 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q9NYB9 and P00519 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q9NYB9 and P00519 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q9NYB9 and P00519 |
Pubmed |
SVM Score :0.0 |
| NA |
|