| Interacting proteins: O60602 and Q99836 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: O60602 and Q99836 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: O60602 and Q99836 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: O60602 and Q99836 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: O60602 and Q99836 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: O60602 and Q99836 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: O60602 and Q99836 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: O60602 and Q99836 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: O60602 and Q99836 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: O60602 and Q99836 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: O60602 and Q99836 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: O60602 and Q99836 |
Pubmed |
SVM Score :0.72768886 |
| Indeed , we demonstrate that the adaptor molecule MyD 88 associates with TLR 5 and silencing MyD 88 expression blocks PI3K activation by disrupting the association between TLR 5 and p 85 . 0.72768886^^^ |
|
| Interacting proteins: O60602 and Q99836 |
Pubmed |
SVM Score :0.0 |
| Immunity to Legionella did not require MyD 88 , an essential adaptor for toll like receptor 5 ( TLR 5 ) signaling . ^^^ |
|
| Interacting proteins: O60602 and Q99836 |
Pubmed |
SVM Score :0.0 |
| The response depended on both extracellular leucine rich repeats and intracellular Toll / IL 1R homology region of TLR 5 as well as the adaptor protein MyD 88 . ^^^ |
|
| Interacting proteins: O60602 and Q99836 |
Pubmed |
SVM Score :0.0 |
| BMMCs and the murine mast cell line MC / 9 expressed mRNA for TLR 2 , TLR 4 , and TLR 6 but not TLR 5 and for both adapter molecule MD 2 and signaling molecule MyD 88 but lacked surface CD 14 . ^^^ |
|
| Interacting proteins: O60602 and Q99836 |
Pubmed |
SVM Score :0.0 |
| Relatively little is known about TLR 5 , the only TLR thought to be preferentially expressed by epithelial cells , beyond that it confers activation of the transcription factor NF kappaB in a MyD 88 dependent manner in response to flagellin . ^^^ |
|
| Interacting proteins: O60602 and Q99836 |
Pubmed |
SVM Score :0.0 |
| The results demonstrated three patterns of gene expression : the TLR 2 and myeloid differentiation factor 88 ( MyD 88 ) gene expressions were induced in AM in response to lipopolysaccharide ( LPS ) , interleukin ( IL ) 1beta , or tumor necrosis factor alpha or in the lung tissue of an LPS induced acute lung injury model ; the gene expressions of TLR 1 , 3 , 6 , CD 14 , and MD 2 were unchanged ; and the TLR 4 and TLR 5 gene expressions were downregulated in AM following inflammatory stimuli . ^^^ |
|
| Interacting proteins: O60602 and Q99836 |
Pubmed |
SVM Score :0.0 |
| The resulting predictions show the presence of one or more counterparts for the human TLR 1 , TLR 2 , TLR 3 , TLR 4 , TLR 5 , TLR 7 , TLR 8 , TLR 9 , IL 1R and IL 18R genes and one copy of the adaptor genes MyD 88 , MAL , TRIF and SARM . ^^^ |
|
| Interacting proteins: O60602 and Q99836 |
Pubmed |
SVM Score :0.0 |
| In this study we show that flagellin , the bacterial stimulus for TLR 5 , drives MyD 88 dependent Th 2 type immunity in mice . ^^^ |
|
| Interacting proteins: O60602 and Q99836 |
Pubmed |
SVM Score :0.0 |
| E . coli MG 1655 flagellin was necessary and sufficient to trigger this pro inflammatory pathway via its interaction with TLR 5 and the subsequent recruitment of the adaptor protein MyD 88 . ^^^ |
|
| Interacting proteins: O60602 and Q99836 |
Pubmed |
SVM Score :0.0 |
| Stimulation of TLR 5 and overexpression of MyD 88 , but not TRIF , TIRAP , or TRAM , result in p 27 degradation , which can be suppressed by dominant negative Akt and mutation of the p 27 C terminal Thr ( 187 ) site . ^^^ |
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