| Interacting proteins: O43236 and Q99719 |
Pubmed |
SVM Score :0.0 |
| A summary of the described functional roles for mammalian septins is discussed along with an attempt to assimilate the alternative nomenclature existing for the same human septins , such as references to PNUTL 1 and PNUTL 2 as hCDCrel 1 and hCDCrel 2 , respectively . ^^^ Characterization and expression analysis of two human septin genes , PNUTL 1 and PNUTL 2 . ^^^ In this report we present the characterization and comparison of two highly similar human septin genes , PNUTL 1 and PNUTL 2 . ^^^ We compare the exon / intron structure of both genes , the steady state mRNA levels in tumor cell lines and adult organs , the conceptual translation products from alternatively processed mRNAs and the development of specific immunologic reagents distinguishing either PNUTL 1 or PNUTL 2 . ^^^ The characterization of PNUTL 1 and PNUTL 2 represents a fundamental step in completing the characterization of the entire family of human septin genes . . ^^^ |
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| Interacting proteins: O43236 and Q99719 |
Pubmed |
SVM Score :0.0 |
| We focus on three septins that are highly expressed in platelets and neurons , SEPT 4 [ previously designated H 5 , CDCrel 2 ( cell division control related 2 ) , PNUTL 2 ] , SEPT 5 ( CDCrel 1 , PNUTL 1 ) and SEPT 8 ( KIAA 0202 ) . ^^^ |
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| Interacting proteins: O43236 and Q99719 |
Pubmed |
SVM Score :0.0 |
| Here we report that Sept 4 , a member of the septin protein family , is consistently found in these inclusions , whereas five other septins ( Sept 2 , Sept 5 , Sept 6 , Sept 7 , and Sept 8 ) are not found in these inclusions . ^^^ |
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| Interacting proteins: O43236 and Q99719 |
Pubmed |
SVM Score :0.0 |
| Thus , SEPT 4 is the third described platelet septin besides SEPT 5 and SEPT 8 . ^^^ Transmission electron microscopy of platelets revealed that SEPT 8 and SEPT 4 are localized surrounding alpha granules ( as it had been shown for the septin SEPT 5 ) suggesting that the three septins may be components of the septin complex in platelets and contribute in such a way to platelet biology . ^^^ |
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| Interacting proteins: O43236 and Q99719 |
Pubmed |
SVM Score :0.0 |
| Immunoreactivity of the septins SEPT 4 , SEPT 5 , and SEPT 8 in the human eye . ^^^ We aimed to examine the distribution of SEPT 4 , SEPT 5 , and SEPT 8 in the human eye . ^^^ For each septin , five to six normal human eyes were examined by immunohistochemical staining of paraffin sections using polyclonal antibodies against SEPT 4 , SEPT 5 , and SEPT 8 and an avidin biotin complex immunodetection system . ^^^ In conclusion , SEPT 4 , SEPT 5 , and SEPT 8 are expressed in various ocular tissues , each revealing a distinct expression pattern . ^^^ |
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| Interacting proteins: O43236 and Q99719 |
Pubmed |
SVM Score :0.0 |
| NA |
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| Interacting proteins: O43236 and Q99719 |
Pubmed |
SVM Score :0.0 |
| NA |
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| Interacting proteins: O43236 and Q99719 |
Pubmed |
SVM Score :0.0 |
| NA |
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