| Human Pumilio 2 is expressed in embryonic stem cells and germ cells and interacts with DAZ ( Deleted in AZoospermia ) and DAZ like proteins . ^^^ Here , we show that PUM 2 , a human homolog of Pumilio , a protein required to maintain germ line stem cells in Drosophila and Caenorhabditis elegans , forms a stable complex with DAZ through the same functional domain required for RNA binding , protein protein interactions and rescue of Pumilio mutations in flies . ^^^ We also show that PUM 2 is expressed predominantly in human embryonic stem cells and germ cells and colocalizes with DAZ and DAZL in germ cells . ^^^ |