Pubmed abstracts for Protein-Protein Interaction search result :


Interacting proteins: Q6PJW1 and Q07960 Pubmed SVM Score :0.0
ARHGAP 8 is a novel member of the RHOGAP family related to ARHGAP1 / CDC42GAP / p50RHOGAP : mutation and expression analyses in colorectal and breast cancers . ^^^ Herein , we describe the identification , characterization and mutational analysis of a novel RHOGAP designated as ARHGAP 8 , which is located within a critical region of loss of heterozygosity on chromosome 22q13 . 31 in breast and colorectal carcinomas . ^^^ Taken together , ARHGAP 8 encodes a novel RHOGAP with unique functional domains that is highly homologous to ARHGAP1 / CDC42GAP / p50RHOGAP . . ^^^
Interacting proteins: Q6PJW1 and Q07960 Pubmed SVM Score :0.0
ARHGAP 1 , ARHGAP 2 , ARHGAP 3 , ARHGAP 4 , ARHGAP 5 , ARHGAP 6 , ARHGAP 7 ( DLC 1 ) , ARHGAP 8 , ARHGAP 9 , ARHGAP 10 , ARHGAP 12 , ARHGAP 13 ( SRGAP 1 ) , ARHGAP 14 ( SRGAP 2 ) , ARHGAP 15 , ARHGAP 17 ( RICH 1 ) , ARHGAP 18 , ARHGAP 19 , ARHGAP 20 , ARHGAP 21 , ARHGAP 22 , ARHGAP 23 , ARHGAP 24 , ARHGAP 25 , ARHGAP 26 , STARD 13 ( DLC 2 ) , HA 1 , GMIP , PARG 1 , RACGAP 1 , PIK3R1 , PIK3R2 , and FNBP 2 genes encode Rho / Rac / Cdc42 like GTPase activating ( RhoGAP ) proteins . ^^^ ARHGAP 1 , ARHGAP 2 , ARHGAP 3 , ARHGAP 4 , ARHGAP 5 , ARHGAP 6 , ARHGAP 7 ( DLC 1 ) , ARHGAP 8 , ARHGAP 9 , ARHGAP 10 , ARHGAP 12 , ARHGAP 13 ( SRGAP 1 ) , ARHGAP 14 ( SRGAP 2 ) , ARHGAP 15 , ARHGAP 17 ( RICH 1 ) , ARHGAP 18 , ARHGAP 19 , ARHGAP 20 , ARHGAP 21 , ARHGAP 22 , ARHGAP 23 , ARHGAP 24 , ARHGAP 25 , ARHGAP 26 , STARD 13 ( DLC 2 ) , HA 1 , GMIP , PARG 1 , RACGAP 1 , PIK3R1 , PIK3R2 , and FNBP 2 genes encode Rho / Rac / Cdc42 like GTPase activating ( RhoGAP ) proteins . ^^^
Interacting proteins: Q6PJW1 and Q07960 Pubmed SVM Score :0.0
Concerted regulation of cell dynamics by BNIP 2 and Cdc42GAP homology / Sec14p like , proline rich , and GTPase activating protein domains of a novel Rho GTPase activating protein , BPGAP 1 . ^^^ We have identified a novel RhoGAP , BPGAP 1 ( for BNIP 2 and Cdc42GAP Homology ( BCH ) domain containing , Proline rich and Cdc42GAP like protein subtype 1 ) , that is ubiquitously expressed and shares 54 % sequence identity to Cdc42GAP / p50RhoGAP . ^^^ Our findings provide evidence that cell morphology changes and migration are coordinated via multiple domains in BPGAP 1 and present a novel mode of regulation for cell dynamics by a RhoGAP protein . . ^^^
Interacting proteins: Q6PJW1 and Q07960 Pubmed SVM Score :0.0
We recently cloned and identified BPGAP 1 as a novel RhoGAP that coordinately regulates pseudopodia and cell migration via the interplay of its BNIP 2 and Cdc42GAP homology , RhoGAP , and the proline rich domains . ^^^
Interacting proteins: Q6PJW1 and Q07960 Pubmed SVM Score :0.0
BPGAP 1 is a novel RhoGAP that co ordinately regulates pseudopodia and cell migration through the interplay of its BNIP 2 and Cdc42GAP homology domains serving as a homophilic / heterophilic interaction device , an enzymic RhoGAP domain that inactivates RhoA and a proline rich region that binds the Src homology 3 domain of cortactin . ^^^
Interacting proteins: Q6PJW1 and Q07960 Pubmed SVM Score :0.0
We recently identified a novel RhoGAP , BPGAP 1 , that uses the BNIP 2 and Cdc42GAP homology ( BCH ) domain , RhoGAP domain and proline rich region to regulate cell morphology and migration . ^^^ Activation of EGF receptor endocytosis and ERK1 / 2 signaling by BPGAP 1 requires direct interaction with EEN / endophilin 2 and a functional RhoGAP domain . ^^^
Interacting proteins: Q6PJW1 and Q07960 Pubmed SVM Score :0.0
NA