| Interacting proteins: Q6FI13 and P09874 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q6FI13 and P09874 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q6FI13 and P09874 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q6FI13 and P09874 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q6FI13 and P09874 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q6FI13 and P09874 |
Pubmed |
SVM Score :0.0 |
| A highly homogeneous 145 base pair fragment of double helical poly ( dA dT ) . poly ( dA dT ) was obtained by micrococcal nuclease digestion of a semisynthetic chromatin prepared from the nucleosome core histones ( H2A , H2B , H 3 , H 4 ) and the synthetic polydeoxyribonucleotide . ^^^ |
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| Interacting proteins: Q6FI13 and P09874 |
Pubmed |
SVM Score :0.0 |
| We have prepared semi synthetic chromatin core particles from a complex of chicken erythrocyte inner histones ( H2A , H2B , H 3 and H 4 ) with double stranded poly ( dAdT ) . poly ( dAdT ) and studied the conformation of the phosphodiester backbone using 31P NMR at 109 . 3 MHz . ^^^ |
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| Interacting proteins: Q6FI13 and P09874 |
Pubmed |
SVM Score :0.0 |
| The results of these studies indicate that poly ( A ( ) ) 4 to 18 S RNA from S phase HeLa polyribosomes contains : ( a ) large quantities of discrete 7 . 4 and 8 S RNA species which are not functional histone mRNA ; ( b ) a discrete 8 . 6 S RNA fraction which contains the templates of human histone H 4 ; ( c ) 9 . 2 to 10 . 7 S RNA which contains mixtures of incompletely resolved histone H2B , H2A , and H 3 mRNA ( These mRNA species do not closely correspond to discrete RNA subfractions resolvable by our techniques . ) ; ( d ) discrete 12 and 13 S RNA fractions which contain templates of human histone H 1 polypeptides . ^^^ |
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| Interacting proteins: Q6FI13 and P09874 |
Pubmed |
SVM Score :0.0 |
| We have found , however , that in Xenopus laevis oocytes , poly ( A ) containing mRNA codes for histones , in a wheat germ cell free system , based on the following criteria : first , co migration with authentic 10 . laevis oocyte histones on polyacrylamide gels ; second , no detectable incorporation of tryptophan ; third , differential incorporation of lysine and methionine into histone fraction H2A ; fourth , resistance of histone fraction H2A to cleavage with cyanogen bromide ; and fifth , correspondence of tryptic peptide maps of partially purified cell free products with authentic 10 . laevis oocyte histone . ^^^ |
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| Interacting proteins: Q6FI13 and P09874 |
Pubmed |
SVM Score :0.0 |
| For the synthesis of these covalent hybrid molecules , we used a population of histones H 1 , H2A , H2B , H 3 , and H 4 from calf thymus and polyadenylic acid with an average chain length of up to 260 280 bases , representing the size of poly ( A ) tails from mature mRNAs . ^^^ |
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| Interacting proteins: Q6FI13 and P09874 |
Pubmed |
SVM Score :0.0 |
| In order to approach and clarify the effect of poly ( ADP ribose ) on the nucleosomal structure , polynucleosomes from calf thymus were incubated with long poly ( ADP ribose ) chains prepared in vitro and examined by ELISA with antibodies directed against the five individual histones H 1 , H2A , H2B , H 3 and H 4 as well as against two synthetic peptides in residues 1 25 of H2B and 130 135 of H 3 . ^^^ |
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| Interacting proteins: Q6FI13 and P09874 |
Pubmed |
SVM Score :0.0 |
| The antisera also contained IgG antibodies which bound components that correspond to common target antigens in autoimmune diseases such as native dsDNA , peptides of Sm D antigen , ubiquitin , branched peptides of ubiquitinated H2A and poly ( ADP ribose ) . ^^^ |
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| Interacting proteins: Q6FI13 and P09874 |
Pubmed |
SVM Score :0.0 |
| Protein kinase p 62 phosphorylates enolase , tubulin and calpactin 1 as well as model substrates in the series : histone H 5 greater than poly ( G , T ) n greater than or equal to histone H2A greater than poly ( G , A , T ) n , histone H 4 greater than caseins , histones H 1 and H2B , poly ( G , A , L , T ) n . ^^^ |
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| Interacting proteins: Q6FI13 and P09874 |
Pubmed |
SVM Score :0.0 |
| At low NAD concentrations the enzyme can poly ( ADP ribosyl ) ate histones H 1 and H 1 , H2A , A2A , and H2B . ^^^ |
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| Interacting proteins: Q6FI13 and P09874 |
Pubmed |
SVM Score :0.0 |
| In contrast , H2B , H2A , H 1 and protein A 24 were poly ADP ribosylated in the nuclear chromatin of the same cells . . ^^^ |
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| Interacting proteins: Q6FI13 and P09874 |
Pubmed |
SVM Score :0.0 |
| The investigated autoimmune panel included a search for antinuclear antibodies , autoantibodies ( in IgG , IgM and IgA isotypes ) to seven phospholipids ( cardiolipin , phosphatidylserine , phosphatidylglycerol , phosphatidylcholine , phosphatidylethanolamine , phosphatidylinositol , and phosphatidic acid ) , to four histone subfractions ( H 1 , H2A , H 3 , H 4 ) , and to four polynucleotides [ ssDNA , dsDNA , poly ( 1 ) , and poly ( dT ) ] , total immunoglobulin levels , and sperm antibody titers . ^^^ |
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| Interacting proteins: Q6FI13 and P09874 |
Pubmed |
SVM Score :0.0 |
| When the pattern of hydrolysis of poly ( ADP ribosyl ) ated histones was analyzed it was found that poly ( ADP ribose ) attached to histone H2B is more resistant than the polymer attached to histone H 1 or H2A or protein A 24 . ^^^ |
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| Interacting proteins: Q6FI13 and P09874 |
Pubmed |
SVM Score :0.0 |
| Interaction of cGMP dependent protein kinase with histones H2A , H2B , H 3 , and H 4 , or poly ( L arginine ) resulted in changes in enzyme conformation such that inactivation of cGMP binding and activation of basal catalytic activity ( assayed without cGMP ) occurred . ^^^ |
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| Interacting proteins: Q6FI13 and P09874 |
Pubmed |
SVM Score :0.0 |
| Minichromosome associated histones H2A and H2B as well as several nonhistone proteins were poly ADP ribosylated by endogenous poly ( ADP ribose ) polymerase . ^^^ |
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| Interacting proteins: Q6FI13 and P09874 |
Pubmed |
SVM Score :0.0 |
| There is a poly ( A ) RNA present in small amounts in the nucleus which ends 600 nucleotides 3 ' to the H2a 614 gene . ^^^ |
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| Interacting proteins: Q6FI13 and P09874 |
Pubmed |
SVM Score :0.0 |
| When poly d ( A T ) was used as a competitor , uH2A bound to this polynucleotide with much greater affinity than histone H2A . ^^^ |
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| Interacting proteins: Q6FI13 and P09874 |
Pubmed |
SVM Score :0.0 |
| However , we have found a number of novel H2a , H2b , and H 3 poly ( A ) + RNA species in avian haploid round spermatids . ^^^ |
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| Interacting proteins: Q6FI13 and P09874 |
Pubmed |
SVM Score :0.0 |
| We studied the poly ( ADP ribosylation ) of the major classes of histones in response to DNA breakage induced by an extracellular burst of active oxygen ( AO ) or the alkylating agent N methyl N ' nitrosoguandine ( MNNG ) in the immortalized human keratinocytes HaCa T using a combination of affinity chromatography on phenylboronate resin and immunoblotting with polyclonal antibodies against histones H 1 , H2B , H2A , H 3 , and H 4 . ^^^ Several histones were constitutively poly ( ADP ribosylated ) in untreated controls : 0 . 03 % of H2A , 0 . 04 0 . 06 % of H2B , and 0 . 04 % of H3 . 1 carried at least one poly ( ADPR ) chain of undetermined length . ^^^ Within 60 min , poly ( ADPR ) substitution had decreased to control levels for H 3 and H 4 and below control levels for H2A and H2B . ( ABSTRACT TRUNCATED AT 250 WORDS ) . ^^^ |
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| Interacting proteins: Q6FI13 and P09874 |
Pubmed |
SVM Score :0.0 |
| Among the histones of the pachytene nucleus , histone subtypes H2A , H 1 and H 3 were poly ( ADP ribosyl ) ated . ^^^ |
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| Interacting proteins: Q6FI13 and P09874 |
Pubmed |
SVM Score :0.0 |
| Despite the presence of a poly ( A ) tail , which is typical of plant histone mRNA but not of animal histone mRNA , the size of the deduced protein and its percentage of homology were closer to animal histone H2As than to plant or lower eukaryotic histone H2A . ^^^ |
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| Interacting proteins: Q6FI13 and P09874 |
Pubmed |
SVM Score :0.0 |
| With the help of partial peptide sequence information , we have isolated and identified CS H 1 , H2A , H2B , H 3 , and H 4 cDNAs from egg poly ( A ) + mRNA of the sea urchin Psammechinus miliaris . ^^^ |
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| Interacting proteins: Q6FI13 and P09874 |
Pubmed |
SVM Score :0.0 |
| Phosphorylation of S 14 of histone H2B and poly ( ADP ribosylation ) of glutamate residues on histone H2A are known markers of DSB in DNA ; these modifications increased 10 40 min after alterations in K 12 biotinylation occurred . ^^^ |
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| Interacting proteins: Q6FI13 and P09874 |
Pubmed |
SVM Score :0.0 |
| Core histones ( H2A , H2B , H 3 , H 4 ) 2 , were reconstituted with the synthetic polynucleotides poly ( dA dT ) 10 poly ( dA dT ) and poly ( dG dC ) 10 poly ( dG dC ) to yield synthetic chromatins containing 200 basepairs per octamer . ^^^ |
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| Interacting proteins: Q6FI13 and P09874 |
Pubmed |
SVM Score :0.0 |
| Competition for CaM occurs with ACTH , beta endorphin , substance P , glucagon , poly ( L arginine ) , myelin basic protein , troponin 1 , and histone H2A . ^^^ |
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| Interacting proteins: Q6FI13 and P09874 |
Pubmed |
SVM Score :0.0 |
| In contrast , the following antibodies of IgG isotype could be much more frequently demonstrated : antibodies to ubiquitinated H2A ( U H2A ) peptide T 4 ( 51 . 7 % in CD ; 18 . 2 % in UC ) , antibodies to the zinc finger peptide F 2 of poly ( ADP ribose polymer ) ase ( PARP ) involved in DNA repair ( 58 . 6 % in CD ; 25 . 5 % in UC ) and actin antibodies ( 43 . 1 % in CD ; 7 . 3 % in UC ) . ^^^ Although we found no obvious correlation between the presence or level of these various antibodies and C reactive protein , or the location of the disease , in a number ( but not all ) of patients , we observed a strikingly good relationship between antibodies to histone peptides , U H2A peptide T 4 , and PARP peptide F 2 and the Crohn ' s disease activity index . ^^^ |
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| Interacting proteins: Q6FI13 and P09874 |
Pubmed |
SVM Score :0.0 |
| Serial bleedings of 27 GVHD mice were screened with a panel of antigens including the five histones H 1 , H2A , H2B , H 3 and H 4 , 15 histone peptides , core particles , dsDNA , heat shock proteins hsp 70 and ubiquitin , a branched peptide of ubiquitinated H2A ( U H2A ) , poly ( ADP ribose ) and SSB / La protein . ^^^ |
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| Interacting proteins: Q6FI13 and P09874 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q6FI13 and P09874 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q6FI13 and P09874 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q6FI13 and P09874 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q6FI13 and P09874 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q6FI13 and P09874 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q6FI13 and P09874 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q6FI13 and P09874 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q6FI13 and P09874 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q6FI13 and P09874 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q6FI13 and P09874 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q6FI13 and P09874 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q6FI13 and P09874 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q6FI13 and P09874 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q6FI13 and P09874 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q6FI13 and P09874 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q6FI13 and P09874 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q6FI13 and P09874 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q6FI13 and P09874 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q6FI13 and P09874 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q6FI13 and P09874 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q6FI13 and P09874 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q6FI13 and P09874 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q6FI13 and P09874 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q6FI13 and P09874 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q6FI13 and P09874 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q6FI13 and P09874 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q6FI13 and P09874 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q6FI13 and P09874 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q6FI13 and P09874 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q6FI13 and P09874 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q6FI13 and P09874 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q6FI13 and P09874 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q6FI13 and P09874 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q6FI13 and P09874 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q6FI13 and P09874 |
Pubmed |
SVM Score :0.0 |
| NA |
|