| Interacting proteins: Q15796 and Q9HCE7 |
Pubmed |
SVM Score :0.0 |
| Smurf 1 also enhances cellular responsiveness to the Smad 2 ( activin / TGF beta ) pathway . ^^^ |
|
| Interacting proteins: Q15796 and Q9HCE7 |
Pubmed |
SVM Score :0.0 |
| Consistent with an inhibitory role in the BMP signaling pathway , the elevated Smurf 1 markedly reduces the level of endogenous Smad 5 , whereas it leaves unaltered that of Smad 2 , Smad 3 , and Smad 7 , which are components of the TGF beta pathway . ^^^ |
|
| Interacting proteins: Q15796 and Q9HCE7 |
Pubmed |
SVM Score :0.0 |
| Smad 2 or Smad 7 mutants defective in Smad 4 interaction failed to induce Smurf 1 mediated down regulation of Smad 4 . ^^^ A Smad 4 mutant defective in Smad 2 or Smad 7 interaction could not be effectively down regulated by Smurf 1 . ^^^ |
|
| Interacting proteins: Q15796 and Q9HCE7 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q15796 and Q9HCE7 |
Pubmed |
SVM Score :0.0 |
| NA |
|