| Interacting proteins: Q13164 and Q02078 |
Pubmed |
SVM Score :0.0 |
| Here , we demonstrate that , in addition to MEF2C , BMK 1 phosphorylates and activates MEF2A and MEF2D but not MEF2B . ^^^ The sites phosphorylated by activated BMK 1 were mapped to Ser 355 , Thr 312 , and Thr 319 of MEF2A and Ser 179 of MEF2D both in vitro and in vivo . ^^^ Site directed mutagenesis reveals that the phosphorylation of these sites in MEF2A and MEF2D are necessary for the induction of MEF2A and 2D transactivating activity by either BMK 1 or by epidermal growth factor . ^^^ |
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| Interacting proteins: Q13164 and Q02078 |
Pubmed |
SVM Score :0.0 |
| It was earlier found that p 38 mitogen activated protein ( MAP ) kinase upregulates c jun gene transcription through phosphorylation of two myocyte enhancer factor 2 ( MEF 2 ) family transcription factors , MEF2A and MEF2C , while big MAP kinase 1 ( BMK 1 ) may upregulate c jun gene transcription through MEF2A , MEF2C , and also MEF2D . ^^^ |
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| Interacting proteins: Q13164 and Q02078 |
Pubmed |
SVM Score :0.0 |
| NA |
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