Pubmed abstracts for Protein-Protein Interaction search result :

Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
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Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
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Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
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Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
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Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
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Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
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Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
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Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
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Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
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Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
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Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
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Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
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Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
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Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
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Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
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Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
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Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
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Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
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Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
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Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
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Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
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Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
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Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
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Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
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Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
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Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
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Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
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Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
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Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
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Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
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Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
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Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
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Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
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Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
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Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
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Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
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Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
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Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
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Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
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Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
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Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
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Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
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Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
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Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
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Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
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Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
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Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
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Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
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Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
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Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
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Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
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Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
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Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
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Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
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Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
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Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
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Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
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Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
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Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
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Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
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Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
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Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
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Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
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Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
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Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
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Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
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Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
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Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
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Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
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Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
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Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
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Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.80036819
The purified RnBP formed a single precipitin line with the antiserum prepared with the purified HMW renin as antigen , which is RnBP renin complex ( Takahashi , S . , et al . ( 1983 ) J . 0.80036819^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.50798514
Levels of aldosterone were significantly correlated with levels of renin in all horses ( r = 0 . 62 , P less than 0 . 001 ) but not with those of cortisol , and renin was negatively correlated with age in male horses ( r = 0 . 54 , P less than 0 . 05 ) . 0.50798514^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
Despite comparable body sodium fluid balance in the two age groups , serum renin concentration , plasma renin activity and aldosterone concentrations were lower in the elderly . ^^^ The age related decreases in circulating renin and aldosterone concentrations were slight while subjects were supine and receiving normal sodium intake ; when upright and during sodium depletion , they were more pronounced . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
The degree of the individual hemodynamic changes after propranolol correlated better with the corresponding control values than with age or renin . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
Renin and age as determinants of a predominantly betablocker based antihypertensive drug program . ^^^ The proportion with low renin hypertension increases with age . ^^^ On this basis , it is postulated that the older patients with a low renin exhibit a relatively hypoadrenergic state whereas those with a normal or high renin for a given age and elevated pressure have a relatively increased adrenergic nervous activity . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
In urine samples of newborns , angiotensin concentrations were in the same range as those found in the amniotic fluid ; renin activity was very low or undetectable in the urine of male neonates ( 1 7 days of age ) . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
Influence of age on orthostatic changes in plasma renin activity and urinary catecholamines in man . ^^^ The authors studied plasma renin activity ( PRA ) , urinary epinephrine , norepinephrine and dopamine excretion and their mutual relationships in 54 healthy subjects under basal ( recumbent ) conditions and age related orthostatic changes in these parameters . ^^^ The diminished capacity of older subjects for catecholamine mobilization and raised renin secretion during an orthostatis stress may be related to the higher incidence of orthostatic forms of hypotension in old age . . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
Plasma cortisol and renin were estimated in 1 h intervals , plasma aldosterone , angiotensinogen and angiotensinases in 3 h intervals over periods of 24 h in six normal volunteers ( age 20 26 ) under control conditions and subsequently under suppression of ACTH release by dexamethasone . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
With increasing age and blood pressure , plasma catecholamine concentrations rise while the reactivity of heart rate and renin secretion decreases . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
In a survey of 3 California communities by the Stanford Heart Disease Prevention Program , we obtained data on blood pressure , medications , age , height and weight , blood for measurement of plasma renin activity ( PRA ) , plasma renin concentration ( PRC ) , plasma renin reactivity ( RR ) , and plasma renin substate concentration ( PRS ) , and urine for measurement of urinary sodium and creatinine . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
A beta blocker based antihypertensive drug program guided by age and renin . ^^^ From analyses of the effectiveness of beta blocker monotherapy in relation to the patient ' s age and to pre treatment renin determinations an antihypertensive drug program is proposed in which beta blockers form the cornerstone . ^^^ The proportion with low renin hypertension increases with age . ^^^ On this basis , it is postulated that the older patients with a low renin exhibit a relatively hypoadrenergic state while those with a normal or high renin for a given age and elevated pressure have a relatively increased adrenergic nervous activity . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
Renin and age , determinants of the beta blocker effect in essential hypertension ] . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
Hypotensive effect following beta adrenergic block in 10 day puppies and alfa adrenergic block in puppies of all age groups is accompanied by the increase in renin activity . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
Patients in this group were older than those with normal renin levels , and there was a significant negative correlation between renin and age among all patients . ^^^ It is concluded that low renin hypertension does not represent a separate diagnostic entity but that plasma renin falls with age in essential hypertension . . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
Relationship of basal plasma noradrenaline to blood pressure , age , sex , plasma renin activity and plasma volume in essential hypertension . 1 . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
The size and number of renin containing GCT cells increased rapidly in males , attaining adult status by 50 days of age . ^^^ In females , differentiation of GCT cells immunoreactive for renin was slower and less regular than in males , and at 50 days of age the GCT segment had not yet reached adult conditions with respect to the distribution of renin . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
None of the following were related independently with variability : age ; race ; sex ; plasma renin activity ; plasma angiotensin 2 ; plasma noradrenaline ; plasma adrenaline . . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
The possibility that bradykinin , a potent vasodilator , might be a physiological antagonist of the renin angiotensin system was investigated . 11 norman subjects , ranging in age from 21 to 33 yr were studied . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
Antihypertensive beta blocking action as related to renin and age : a pharmacologic tool to identify pathogenetic mechanisms in essential hypertension . ^^^ The proportion of patients with low renin hypertension progressively increased with increasing age and blood pressure , there being no difference between the sexes . ^^^ Age may heolp in patient selection but is no substitute for the more reliable renin index , especially in patients over age 40 years , or with high pressure . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
The hypertension is characterized by low plasma renin activity and , with increasing age , normal to high plasma aldosterone . 3 . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
Blood pressure , plasma renin activity , plasma aldosterone , urinary noradrenaline during sleep ( UNA S ) and several estimates of sodium intake were determined in 379 normotensive subjects ( age 13 70 ) to investigate the relationship of these variables to blood pressure . 2 . ^^^ Blood pressure was correlated with age , weight , plasma renin activity UNA S , and estimates of sodium intake . ^^^ Multiple correlation analysis revealed that after removal of the effects of age , blood pressure was related to weight , plasma renin activity , UNA S and estimates of sodium intake . 4 . ^^^ However , multiple regression analysis failed to demonstrate an effect of plasma renin activity , UNA S , or estimates of sodium intake on blood pressure when the effects of age , weight , race and sex were removed . 5 . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
Plasma noradrenaline concentration and plasma renin activity were measured in a control , British , urban population ( n = 115 ) in which blacks were matched for age and sex with whites . 2 . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
Strict criteria were employed for renin profiling the hypertensive patients , including age matching , exclusion of diabetics , and the use of medications known to interfere with the renin response or with DOC measurements . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
Plasma aldosterone concentrations and plasma renin activity according to age and their relationships with electrolytes of plasma and erythrocyte and oral sodium intake in normal neonates and children ( author ' s transl ) ] . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
To characterize the renin angiotensin system in the Aoki Okamoto spontaneously hypertensive rat ( SHR ) more fully , serial measurements of plasma renin activity ( PRA ) , plasma renin concentration ( PRC ) , renin reactivity ( as relative index of circulating modifiers of the renin reaction ) and renin substrate concentration were made in 6 to 64 week old SHR and in age matched Wistar Kyoto normotensive rats ( WKY ) . ^^^ However , elevated renin reactivity did not account for the transition from normal to high PRA observed in mature SHR , nor did renin substrate concentration , which was consistently lower in SHR than in age matched WKY . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
Simultaneous measurement of plasma renin activity ( PRA ) , plasma aldosterone concentration ( PA ) and urinary aldosterone excretion ( UAE ) was made using the RIA method along with determination of Na and K balance in 1 week old neonates with gestational age of 30 41 weeks ( mean 35 . 9 weeks ) and birth weight of 1 , 160 4 , 670 g ( mean 2 , 680 g ) . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
In essential hypertension mean basal ( supine ) and stimulated plasma renin activity ( 2 h upright posture + 40 mg furosemide intraveneously ) decreased progressively with age . ^^^ In female patients changes in mean stimulated plasma aldosterone with increasing age paralleled those of plasma renin activity , whereas in males this relationship was less obvious : only a slight age related decline in stimulated aldosterone levels was observed and significantly lower plasma aldosterone concentrations in male than in female hypertensives of the younger age groups ( less than 40 years ) were found . ^^^ The results indicate that in essential hypertension with increasing age dissociation between plasma aldosterone and plasma renin activity occurred . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
The renin activity of plasma the age dependence and prognostic and therapeutic significance ( author ' s transl ) ] . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
The fluctuation of plasma renin activity in response to an excess of sodium chloride or to thiazide treatment was reduced progressively with age . ^^^ The age related decrease of plasma renin activity is discussed on the light of the age related impairment in the ability of the kidney to excrete sodium and water . . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
The study presented here clearly shows that age and sex have an important influence on plasma renin activity . ^^^ Women had lower values than age matched men , and studies in normal volunteers showed that plasma renin activity decreases with age . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
Influence of age on the renal renin response to a high salt intake in the rat . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
A sample of 278 children , stratified by diastolic ( fourth phase ) blood pressure and specific for age , race , and sex , was reexamined 1 2 yr after initial observation for the following : ( 1 ) a physical examination and urinalysis to exclude secondary hypertension ; ( 2 ) 24 hr urine sodium , potassium , plasma renin activity , and serum dopamine beta hydroxylase ; ( 3 ) 1 hr oral glucose tolerance test ; and ( 4 ) heart rate and blood pressure at rest and under standarized physical stress . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
The poor responsiveness of the RAS in Group 2 is attributed to an inadequate adrenergic activity and to an increased mean arterial pressure in that group , but the higher age of patients and longer duration of hypertensive disease , both characteristic of the group of medium severity , may also effect the renin angiotensin system . . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
The highest mean age and the longest duration of the disease history are typical for patients with low plasma renin activity . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
Plasma renin activity ( PRA ) and plasma aldosterone concentration ( PA ) were measured in 20 healthy infants 2 12 months of age , after taking a commercial modified cow ' s milk formula with 8 . 2 mmol / l sodium for at least five days , and after at least five days on a home made , undiluted acidified cow ' s milk formula with 12 . 6 mmol / l sodium . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
Total kidney renin content increases with age . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
Relationships between blood pressure , age , plasma renin activity and electrolyte excretion in normotensive subjects . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
Patient age , blood pressure , and plasma renin activity did not differ between the two races . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
With this treatment , plasma renin activity and aldosterone were normal or almost normal beyond the age of 6 . 5 months , but urinary aldosterone 18 glucuronide remained slightly increased . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
Using RIA for determining the plasmatic renin activity in orthostatism according to the method of Fyhrquist we obtained in the control group of adult subjects nonsignificant variations in relation with sex and age , and in the group with Cushing ' s syndrome associated with arterial hypertension nonsignificantly increased values as against the controls . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
Age , blood pressure , renin and urinary electrolytes in primary hypertension and in the normotensive state . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
Groups of patients with low and high renin hypertension differed significatly from each other not only br PRA after stimulation , but also by PRA at rest , PV and age . . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
An inverse relationship between the aortic renin content of the spontaneously hypertensive rat and the progressive increase of systolic blood pressure was observed with age . ^^^ In contrast to this strain of rat , aortic renin of the normotensive WKY strain did not decline with age . 3 . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
Plasma renin activity was lower in 89 previously untreated `` hypertensive ' ' subjects than in an equal number of age and sex matched `` controls ' ' from the same community . ^^^ Plasma renin activity fell with both increasing age and increasing arterial pressure . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
Whilst there were significant differences in age between the high , normal and low renin groups , there were no significant differences in basal blood pressure , response to diuretics or beta blockers . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
Changes in plasma renin levels of normotensive and spontaneously hypertensive rats with increasing age [ proceedings ] . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
A significant decrease in renin activity was revealed in males and females over 40 years of age with labile and stable forms of hypertensive disease . . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
The molecular weight of plasma renin of female WK at the age of 90 , 120 , and 200 days ranged from 41 , 000 to 43 , 000 showing little variation . 3 . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
Age versus urinary sodium for judging renin , aldosterone , and catecholamine levels : studies in normal subjects and patients with essential hypertension . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
Plasma renin activity was related to race and inversely to age in hypertensive patients ( P less than 0 . 05 ) but not in normal subjects . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
Plasma renin activity , arterial and venous angiotensin 2 ( A 2 ) concentrations , and plasma aldosterone concentration were measured in 16 normal subjects ( mean age = 34 years ) after 8 hours of recumbency , following 2 hours of ambulation , and again 30 minutes after administration of furosemide intravenously . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
Plasma renin activity ( PRA ) , supine , erect and post frusemide ( 1 mg / kg 4 ) was studied in 51 patients with previously untreated essential hypertension and their age and sex matched normotensive controls . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
Plasma renin concentration correlated inversely with both total peripheral and renal vascular resistance as well as with age . ^^^ Multiple regression analysis indicated that part of the relationship between renin and haemodynamic variables did not depend on age . ^^^ Furthermore , plasma renin concentration did not decrease with age in a group of 40 normotensive control subjects of similar age to the hypertensive patients . 4 . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
There were no differences with age , sex and severity of hypertension except for the level of peripheral plasma renin activity between the two groups . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
This is indicated by the observation that prevalence of low renin hypertension increases with age and that it is more frequent in advanced stages of hypertension . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
Interrelations between age and plasma renin , aldosterone and cortisol , urinary catecholamines , and the body sodium / volume state in normal man . ^^^ Interrelations between age and plasma renin , aldosterone and cortisol levels , urinary catecholamiens , plasma and blood volumes , exchangeable body sodium and blood pressure wwere studied in 28 young ( 19 to 29 years ) , 16 middle aged ( 32 to 58 years ) and 15 elderly ( 60 to 74 years ) healthy subjects . ^^^ There were no significant age related differences in the body sodium / volume state , basal plasma cortisol levels or urinary adrenaline excretion rate , and plasma renin or aldosterone levels did not correlate with these parameters or with blood pressure . ^^^ It is concluded that the influence of age on plasma renin or aldosterone levels , plasma cortisol responsiveness to upright posture , and urinary noradrenaline excretion should be taken into consideration , whenever these factors have to be interpreted in patients with arterial hypertension or other clinical disorders . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
Plasma renin activity ( PRA ) , aldosterone ( Aldo ) , 17alpha hydroxyprogesterone ( 17 OHP ) and testosterone ( T ) , together with urine sodium , pregnanetriol , 17 oxosteroids and the 11 oxygenation index ( 11 OH ) were estimated in 23 patients ( age 5 . 7 18 yrs . ) with congenital adrenal hyperplasia ( CAH ) due to 21 hydroxylase deficiency during glucocorticoid treatment . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
The relationship of plasma and urinary aldosterone with sodium balance , plasma renin activity and age in normal subjects . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
Age and the renin aldosterone system . ^^^ Age effect on plasma renin activity ( PRA ) and PRA classification was studied in young and older normotensive volunteers . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
Plasma renin activity under both test conditions declined with increasing age , especially those over 40 . ^^^ Response of renin activity to sodium restriction and standing was 73 per cent of that of the younger age group . ^^^ Renin substrate did not decline with increasing age . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
The mean level of plasma renin activity fell with increasing age of hypertensive patients . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
In babies ranging in age from 1 to 25 weeks and in children between 1 and 14 years , plasma renin activity and urinary aldosterone activity were determined in relation to urinary sodium excretion . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
Plasma renin activity in normal children : its relationship to age and rates of excretion of sodium and potassium . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
Postural changes in plasma renin activity were studied in three groups of age and duration matched male diabetics ( potent , impotent and with postural hypotension ) and in non diabetic control subjects . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
Compared with a group of normal pregnant women , matched for age , parity , posture , and length of gestation , women with hypertension and proteinuria in the last trimester had significantly lower plasma concentrations of renin , renin substrate and angiotensin 2 . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
A statistically significant reverse relationship was found between the age of the hypertensive patients and their plasma renin activity ; this parameter tends to decrease along with the increasing duration of the disease . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
The results were compared to data of 5 patients under propranolol matched according to age , arterial blood pressure , and renin concentration . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
Plasma renin activity and plasma aldosterone in essential hypertension : effect of age and diastolic blood pressure ] . ^^^ In patients with essential hypertension a gradual decrease in basal and stimulated renin secretion was found with increasing age . ^^^ Young patients ( less than 35 years ) with high renin hypertension had lower diastolic blood pressure than patients with low renin hypertension in the same age group . ^^^ Contrary to these findings , a markedly higher diastolic blood pressure was observed in patients over 35 years of age with high renin hypertension than in the group of patients with low renin hypertension . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
Once daily dosage beta blockade : antihypertensive efficacy of slow release oxprenolol as related to renin and age . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
Reduced plasma renin activity in essential hypertension : effects of blood pressure , age and sodium . 1 . ^^^ Supine plasma renin activity and its responsiveness to erect posture and frusemide were reduced in fifty one patients with essential hypertension , compared with fifty one age and sex matched control subjects . 2 . ^^^ A significant inverse relationship between plasma renin activity and age , independent of blood pressure , was shown in hypertensive patients and control subjects . 5 . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
Analysis of relationships between blood volume , vascular capacitance , cardiopulmonary and peripheral blood volumes , labelled albumin disappearance rate , plasma renin activity , blood pressure and age was performed in essential hypertensive males . 2 . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
Plasma catecholamines were raised in 70 % of ' high ' renin patients with primary hypertension ( group 2 ) , were related directly with age in normotensive females and were related inversely with catecholamine responses to postural stress in both normotensive and hypertensive subject ( P less than 0 01 ) . 3 . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
Renin and heart rate responses to exercise and beta receptor blockade diminished from high renin to normal and to low renin patients , effects which were blunted with increasing age . 3 . ^^^ Long term anti hypertensive propranolol effects correlated with pre treatment renin status , renin stimulation and its suppression by acute beta receptor blockade as well as with the exercise tachycardia and the patient ' s age . 5 . ^^^ The results suggest different adrenergic control mechanisms in renin sub types of essential hypertension , age being a modulating factor . . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
The incidence of low renin hypertension , when age and race are taken into account , is much lower than previously assumed . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
Also , peripheral plasma levels of aldosterone and plasma renin activity were determined in both the spontaneously hypertensive and the normotensive rats at 7 8 weeks of age . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
The findings emphasise the need to relate data from patients to age matched control values before attempting interpretation and suggest that sodium depletion is a more potent stimulator of renin aldosterone release than renovascular disease or renal scarring in children . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
In 5 volunteers with essential hypertension ( age between 32 and 48 years ) plasma renin activity ( PRA ) was determined and right heart catheterization and femoral artery pressure measurements were carried out at rest and during isometric exercise by handgrip . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
The stroke prone strain showed significantly higher plasma renin levels at and after seven months of age , while the stroke resistant strain showed no significant differences from the control at any age . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
In order to elucidate the main factors controlling plasma aldosterone in infancy and childhood , plasma renin activity ( PRA ) , plasma cortisol ( PC , as a parameter of ACTH activity ) , plasma aldosterone ( PA ) and serum sodium and potassium were measured simultaneously in 84 healthy children ( 62 recumbent , 22 upright ) ranging in age from 6 days to 16 years . 10 healthy male students served as adult controls . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
The effect of age and norepinephrine on renin release by rat kidney slices in vitro . ^^^ Basal renin release by rat kidney slices decreases with age in rats of SHR and Sprague Dawley strains . ^^^ In contrast , Kyoto Wistar rats ( from which SHR are derived ) demonstrate no decrease in renin release with age . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
Plasma renin activity as a function of age in two new strains of spontaneously hypertensive and normotensive rats . 1 . ^^^ Plasma renin activity was significantly higher in young spontaneously hypertensive than in normotensive rats of the same age ( 5 7 weeks ) . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
Potassium ( 100 mM ) enhanced this activity but sodium or calcium had no effect . 2 Uterine renin like activity was unchanged 24 h after bilateral nephrectomy . 3 Renin like activity in the uterus increased slowly from birth to 4 weeks of age and faster between the 4th and 8th week . 4 Ovariectomy caused a considerable fall in uterine renin like activity . 5 The following factors , known to affect renin secretion in the kidney , i . e . , hypovolaemia , sodium loading , adrenalectomy , administration of desoxycorticosterone acetate and injection of isoprenaline , had no effect on uterine renin like activity . 6 Stilboestrol , an oestrogen , caused a significant increase of uterine renin like activity . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
The groups were similar with respect to plasma renin activity , renin response to ultrafiltration , age , duration of dialysis , nerve conduction velocity , plasma protein concentration , hematocrit , dialysis weight change , resting heart rate , sex , race , blood pressure and heart rate response to cold pressor test , and 125I albumin plasma volume . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
The present study was undertaken to assess the influence of acute metabolic acidosis on the activity of renin angiotensin aldosterone system and renal function in a group of seven one week old neonates with mean birth weight of 2164 g ( range : 1300 3750 g ) and mean gestational age of 34 weeks ( range : 28 40 weeks ) undergoing oral NH4Cl load . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
Seventeen of these patients ( age 26 + / 7 years ) , so far untreated , were investigated prospectively for hormone levels ( renin , aldosterone , vasopressin ) , microalbuminuria , renal haemodynamics ( inulin and PAH clearance ) and signs of organ damage ( echocardiography , fundoscopy ) . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
As the mouse Ren 2d renin gene is integrated into their genome , they develop fulminant hypertension between 5 and 15 weeks of age , with blood pressure maxima of 300 mm Hg . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
Effect of oestradiol was studied on the angiotensin converting enzyme ( ACE ) a component of renin angiotensin system , in oviduct of immature quails of 15 days of age . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
Effects of age and posture on plasma active renin and plasma inactive renin in normal subjects . ^^^ To investigate the effects of age and posture on plasma active and inactive renin , we measured the plasma active renin concentration ( ARC ) and inactive renin concentration ( IRC ) in 81 healthy subjects . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
The influence of age on renal function and renin and aldosterone responses to sodium volume expansion and contraction in normotensive and mildly hypertensive humans . ^^^ To determine the effects of age on the responses of renin , aldosterone ( PA ) , sodium excretion , and renal function to provocative maneuvers , we performed volume expansion and contraction in 390 normotensive and 212 hypertensive subjects in the second to seventh decades of life . ^^^ Plasma renin activity decreased with age under basal , stimulated , and suppressed conditions ; the decrease was greater in hypertensives than in normotensive persons . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
Tissue specific regulation of renin binding protein gene expression in rats . ^^^ Rat gene for renin binding protein ( RnBP ) was shown to be expressed in the kidney , adrenal gland , brain , lung , spleen , ovary , testis , and heart . ^^^ The RnBP existed as a homodimer and formed a heterodimer with rat renin to inhibit renin activity extensively . ^^^ Intravenous injection of the RnBP into rats resulted in a rapid and strong inhibition of plasma renin activity , which persisted at least for 2 h . ^^^ These results suggest that the expression of RnBP gene in the kidney and adrenal gland is regulated independently , and the function of RnBP is related to electrolyte homeostasis , probably through the interaction with renin . . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
The complex included evaluation of blood lipid spectrum ( HDL , LDL , VLDL , triglycerides ) , hemostasis ( coagulation , platelet aggregation , fibrinolysis ) , hormonal profile ( blood hydrocortisone , aldosterone , testosterone , estradiol , STH , FSH , LH , prolactin , plasma renin activity ) , central and intracardiac hemodynamics , ECG . 66 healthy men of advanced age served control . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
To determine whether high protein feeding throughout development affects renal growth , renal hemodynamics , and the intrarenal distribution of renin and its mRNA in the adult animal , male Wistar rats were fed diets containing either 20 % protein [ normal ( NP ) , n = 12 ] or 40 % protein [ high ( HP ) , n = 12 ] from weaning until studied at 6 or 12 wk of age . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
Effect of age and blood pressure on the heart rate , vasopressin , and renin response to hypoxia in fetal sheep . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
Plasma renin activity ( PRA ) declines with age in normal individuals , but the effect of age on plasma angiotensin 2 ( ANG 2 ) is less clear . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
The lack of the circadian rhythm for ANP along with the divergent changes in ANP and PRA 24 hr mean concentration of elderly subjects both suggest that ANP exerts with advancing age only a counterregulatory role on the tonic rather than the phasic release of renin . . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
Conversely , patients with low renin activity are protected from heart attack despite higher blood pressures and greater age . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
The plasma and adrenal renin angiotensin system in stroke prone spontaneously hypertensive rats ( SHRSP ) and Wistar Kyoto ( WKY ) rats were examined in animals at 5 , 11 , 18 , and 25 weeks of age . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
These data were compared with age , serum potassium level , plasma renin activity ( PRA ) and in 14 patients with left ventricular mass , measured echocardiographically . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
Comparing FH 2 patients with 88 patients with primary aldosteronism of other causes revealed no differences in mean age at presentation or at onset of hypertension , sex incidence , lowest recorded serum potassium , plasma aldosterone , plasma renin activity or adenoma size . 4 . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
The effects of prostacyclin infusion ( 6 . 7 + / 2 . 7 ng / kg / min , 3 to 10 ng / kg / min ) on blood pressure , plasma renin activity ( PRA ) , and 6 keto prostaglandin F 1 alpha ( 6 keto PGF 1 alpha ) were studied in 7 patients with essential hypertension ( 4 men and 3 women ) with a mean age of fifty eight + / eleven years ( forty six to seventy four years ) . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
The plasma aldosterone level and plasma renin activity ( PRA ) were very high 290 ng / ml and 100 ng / dl per hour , respectively ( normal range for this age 2 . 6 20 . 8 ng / ml and 1 . 2 2 . 7 ng / ml per hour , respectively ) . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
Modulation of active renin secretion by renin binding protein ( RnBP ) in mouse pituitary AtT 20 cells transfected with human renin and RnBP cDNAs . ^^^ To investigate the role of renin binding protein ( RnBP ) in renin metabolism , RnBP expression plasmid , which was constructed to express human RnBP under the control of mouse mammary tumor virus long terminal repeat , was transfected into mouse pituitary AtT 20 cells together with the expression plasmid encoding human renin . ^^^ The transfectant secreted prorenin and active renin , whereas RnBP was expressed only in the presence of dexamethasone and without secretion into the medium . ^^^ Coexistence of RnBP and renin mRNAs in human Wilms ' tumor G 401 cells was shown by means of polymerase chain reaction of respective cDNAs from the cells . ^^^ These results suggest that RnBP modulates the release of active renin in renin producing cells . . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
Plasma renin decreased with age in patients with renovascular hypertension and essential hypertension . ^^^ Stimulated plasma renin activity and the net increase in plasma renin activity after captopril administration in patients with essential hypertension showed a significant decrease with age . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
This age dependency of the renal RI and , hence , of the renal vascular resistance might be dependent on levels of active renin , as the maturational profile of the renal RI more closely parallels that of active renin than those of other renal functional parameters . . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
The antihypertensive effects of the renin inhibitor enalkiren were compared with those of the angiotensin converting enzyme inhibitor enalaprilat in 17 hypertensive patients ( 14 white , 3 black ; mean age 57 years ) , whose renin systems had been stimulated by diuretic pretreatment . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
Serum and urine sodium , plasma renin activity , serum ADH , cardiac index , effective renal plasma flow , and total blood volume were measured in seven burn patients ( mean age , total burn size , and postburn day : 32 years , 56 % , and 9 days , respectively ) . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
RESULTS The four randomised groups of patients had similar age , severity of heart failure ( NYHA class ) , pretreatment diuretic dosage , plasma renin activity , and serum electrolyte state . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
Blood pressure ( BP ) tended to be higher in the former group ( p less than 0 . 005 ) but age , urinary sodium excretion , plasma renin activity , and aldosterone levels or creatinine clearance were comparable . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
Age and reactivity of sympathetic and / or renin activity may play a major role in determining the response of cardiac mass to BP lowering . . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
Serum renin activity was measured in 35 women aged 18 57 ( mean age = 37 . 3 ) with Graves Basedow hyperthyreosis , before and after the thyrostatic treatment . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
These findings suggest that as the duration of diabetes and the age of the animal lengthens , there is a decrease in the number of cells expressing the renin gene . . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
The present study has demonstrated that in contrast to individuals with normal or high renin activity and of the same age and the same degree of heart failure , patients with its low levels are better protected against arrhythmias and severe and therapy resistant heart failure . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
Furthermore , membrane angiotensin 2 receptors were measured in trophoblastic tissues . 2 . ) Blood and tissue concentrations of total renin , active renin , angiotensin 2 and steroids are shown to increase with gestational age . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
Plasma concentrations of atrial natriuretic peptide and aldosterone and plasma renin activity were measured in patients with peripartum heart failure and in age matched healthy women post partum . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
The effectiveness of CEB might be explained by some characteristics of old age , such as elevated mean blood pressure , reduced plasma renin activity , blunted sympathetic activity , altered drug pharmacokinetics and so forth . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
We measured plasma ANP , plasma renin activity ( PRA ) , plasma aldosterone , serum estradiol 17 beta and progesterone concentrations in 103 normotensive women , either in premenopause ( n = 35 ; mean age : 24 years ) , in physiological menopause ( n = 34 ; mean age : 43 years ) or surgically induced menopause ( n = 34 ; mean age : 55 years ) . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
To test the prognostic value of plasma renin activity prospectively , we determined the pretreatment renin sodium profile of 1717 subjects with mild to moderate hypertension ( mean age , 53 years ; 36 percent white ; 67 percent men ) in a systematic work site treatment program . ^^^ Renin profiles , obtained by plotting plasma renin activity against the urinary excretion of sodium , were classified as high ( 12 percent of the subjects ) , normal ( 56 percent ) , and low ( 32 percent ) , and there were expected variations according to age , sex , and race . ^^^ As adjusted for age , sex , and race , the incidence of myocardial infarction per 1000 person years was 14 . 7 among the subjects with a high renin profile , 5 . 6 among those with a normal profile , and 2 . 8 among those with a low profile ( rate ratio for high vs . low , 5 . 3 ; 95 percent confidence interval , 3 . 4 to 8 . 3 ) . ^^^ The independent association of a high renin profile with myocardial infarction ( but not with stroke or noncardiovascular events ) was affirmed by Cox analyses ( rate ratio for high vs . normal plus low , 3 . 2 ; 95 percent confidence interval , 1 . 2 to 8 . 4 ) after adjustment for race , sex , age at entry , serum cholesterol level , smoking status , electrocardiographic evidence of left ventricular hypertrophy , blood glucose level , body mass index , history of cardiovascular disease or treatment , blood pressure , and use of beta blockers . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
Atrial natriuretic factor increased with age in women but not in men ( r = 0 . 60 , p less than 0 . 001 ) , and plasma renin activity decreased ( r = 0 . 35 , p less than 0 . 02 ) . ^^^ Thus , in women , increase in LV chamber size with age and associated changes in LV systolic function , atrial natriuretic factor levels and plasma renin activity suggest plasma volume expansion related to the aging process . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
Renal renin secretion was examined in renal superficial cortical slices from spontaneously hypertensive rats ( SHR ) and Wistar Kyoto rats ( WKY ) at 4 wk ( prehypertensive ) , 6 wk ( early hypertensive ) , and 12 wk ( established hypertension ) of age . ^^^ Angiotensin 2 ( ANG 2 ) resulted in a significant reduction in renin release in both SHR and WKY at 10 ( 7 ) M in all age groups . ^^^ The ANG 2 induced percent change in renin release from control of SHR was less compared with WKY rats at 10 ( 8 ) and 10 ( 9 ) M at 4 wk of age . ^^^ These data document increased basal renin release and ANG 2 binding sites in proximal tubular BBM in 4 wk SHR compared with age matched WKY rat . ( ABSTRACT TRUNCATED AT 250 WORDS ) . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
The purpose of this study was to examine the relationship between the variability of awake ambulatory blood pressure and the level of plasma renin activity ( PRA ) in age matched samples of untreated hypertensive white men . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
At 3 year 6 month of age she suddenly developed hypertension ( the plasma renin activity was found to be 16 . 6 ng / m / hr . and the aldosterone 220 ng / dl ) . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
Her ratio of plasma renin activity to urinary aldosterone 18 glucuronide excretion was 1 . 7 after three days of sodium restriction , as compared with a ratio of 4 . 7 at the age of nine years ( normal range , 0 . 03 to 0 . 1 ) . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
We examined factors ( blood pressure , plasma renin activity , and age ) influencing the antihypertensive response in essential hypertensive patients given 240 mg / day of slow release diltiazem in an unblinded study after a placebo run in period . ^^^ Subjects provided a range of diastolic blood pressures ( 90 to 115 mm Hg ) , of age ( 31 to 70 years ) , and of plasma renin activity ( 0 . 1 to 2 . 7 ng angiotensin I / ml / hr ) on a 70 to 150 mEq sodium diet . ^^^ Multiple linear stepwise regression of change in blood pressure versus age , plasma renin activity , and baseline blood pressure showed baseline blood pressure was the only predictor of response ( p = 0 . 0002 ) . ^^^ We conclude that patient age and plasma renin activity are not clinically significant predictors of antihypertensive response to diltiazem in hypertension . . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
When maintained on Stroke Prone Rodent Diet and saline , plasma renin activity of untreated SHRSP surviving until 14 . 5 weeks of age was markedly increased ( 29 . 1 + / 9 . 4 ng Ang I / mL / h ) compared with either untreated SHRSP ( 9 . 2 + / 2 . 5 ng Ang I / mL / h , P less than . 01 ) or Wistar Kyoto rats ( 3 . 5 + / 1 . 0 ng Ang I / mL / h , P less than . 01 ) maintained on standard diet and water . ( ABSTRACT TRUNCATED AT 250 WORDS ) . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
This antihypertensive effect was not related to baseline plasma renin activity levels or age . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
The present study was undertaken to assess the effects of acute metabolic acidosis on the activity of the renin angiotensin aldosterone system in 12 children with a mean age of 8 . 9 years who underwent NH4Cl loading test . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
Using multiple regression analysis , baroreflex sensitivity ( BS ) correlated positively to stroke volume index ( SVI ) and inversely to plasma renin activity ( PRA ) and to age : BS = 0 . 47 SVI 0 . 38 PRA 0 . 23 age + constant ( r = 0 . 74 ; p less than 0 . 0005 ) . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
At baseline , subjects who developed hypertension had a greater left ventricular mass index than those who did not ( 92 + / 25 compared with 77 + / 19 g / m2 body surface area ; P less than 0 . 005 ) and higher 24 hour urinary sodium / potassium excretion ratio ( 3 . 6 + / 1 . 7 compared with 2 . 6 + / 1 . 4 ; P less than 0 . 04 ) ; there were no differences in race , initial age , systolic or diastolic blood pressure , coronary risk factors , or plasma renin activity . ^^^ In multivariate analyses , follow up systolic pressures in all subjects and in the 117 who remained normotensive were predicted by initial age , systolic blood pressure , black race , and sex adjusted left ventricular mass index ; final diastolic blood pressure was predicted by its initial value , plasma triglyceride levels , urinary sodium / potassium ratio , low renin activity , black race , and plasma glucose level . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
The levels of plasma renin , kidney renin , and kidney renin mRNA were examined in 6 and 9 wk old transgenic mice and were found to be significantly lower than their age matched non transgenic littermates and were nonresponsive to captopril treatment . ^^^ The levels of renal renin mRNA in transgenics and nontransgenic littermates were compared throughout ontogeny and were found to be equal in newborns , elevated 3 to 5 fold in 1 wk old transgenics , and yet decreased 10 fold by 6 wk of age in transgenic mice . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
Leucine zipper motif in porcine renin binding protein ( RnBP ) and its relationship to the formation of an RnBP renin heterodimer and an RnBP homodimer . ^^^ An apparent leucine zipper motif was recognized in the predicted amino acid sequence of porcine kidney renin binding protein ( RnBP ) by analysis of the nucleotide sequence of a cDNA encoding the protein ( Inoue , H . , Fukui , K . , Takahashi , S . , and Miyake , Y . ( 1990 ) J . ^^^ To evaluate the role of this motif in the formation of an RnBP renin heterodimer and an RnBP homodimer , a porcine mutant cDNA involving Leu 185 Asp and Leu 192 Asp substitutions was constructed and expressed in vitro and in Xenopus oocytes . ^^^ The results strongly suggest that the leucine zipper motif in the RnBP molecule mediates the formation of both the RnBP renin heterodimer and the RnBP homodimer observed previously . ^^^ The existence of the motif should facilitate elucidation of the role of RnBP in renin metabolism . . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
Although short term administration of spironolactone raised renin and aldosterone markedly and lipids moderately ( possibly because of volume contraction ) , the present results show that perindopril and spironolactone are both safe and effective for treating hypertension at the age of 50 or older . . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
A mean sodium supplement of 2 . 2 mmol / kg per day ( range 0 . 5 4 . 9 ) , double the amount provided with feeds , was required to maintain plasma sodium concentration and plasma renin activity ( PRA ) in the normal range for age . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
Furthermore , there were only weak correlations between plasma renin activity and plasma norepinephrine and hemodynamic measurements , age , and renal function , indicating that activation of these systems is complex and determined by many other factors . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
There was no relation between the responsiveness to enalapril ( Emax or Ce 50 ) and patient age or plasma renin activity , but there was a significant positive correlation between Emax and the pretreatment blood pressure . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
The glomerular response in hypertensive patients was independent of age , duration of hypertension , blood pressure , plasma renin activity , urinary albumin excretion and retinal vascular alterations . 4 . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
Plasma renin concentration ( PRC ) and plasma and pulmonary angiotensin converting enzyme ( ACE ) concentration were measured in fetal and neonatal guinea pigs from 45 days gestational age ( GA ) until 21 days post partum . 2 . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
Age dependent effects of chronic hypoxia on renin angiotensin and urinary excretions . ^^^ To evaluate the long term effects of chronic hypoxia on water balance , urinary electrolyte excretion , heart weights , systemic arterial pressure , and components of the renin angiotensin system , male Sprague Dawley rats were exposed to periods of simulated altitude of 10 , 000 ft up to 90 days of age beginning at 2 or 30 days of age . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
Increased ADH , which usually suppresses plasma renin activity , was associated with increased plasma renin activity of 11 55 ng angiotensin 1 / mL / h ( normal for age less than 10 ng angiotensin 1 / mL / h ) . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
Molecular cloning and sequence analysis of a cDNA encoding a porcine kidney renin binding protein . ^^^ A complementary DNA encoding a renin binding protein ( RnBP ) has been isolated from a porcine kidney cDNA library by immunological screening of in vitro translation products from the cDNAs . ^^^ The in vitro translated RnBP was found to have the same molecular weight , 42 , 000 , as that of the purified RnBP from porcine kidney on sodium dodecyl sulfate polyacrylamide gel electrophoresis and it formed a complex with renin purified from porcine kidney , which indicates that the cDNA encodes a functional RnBP without a propeptide sequence . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
Distribution of renin mRNA and immunoreactive renin ( IR ) was examined in kidneys of 1 mo old Sprague Dawley rats subjected to either sham operation ( n = 21 ) , left complete UUO ( n = 21 ) , or right uninephrectomy ( UNX , n = 16 ) at 2 days of age . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
Interrelations were investigated between blood pressure , plasma epinephrine ( E ) , norepinephrine ( NE ) , dopamine ( D ) , aldosterone , cortisol concentrations , active and inactive plasma renin activity ( PRA ) , and age in 21 normotensive subjects ( aged 20 60 years ) and in 25 patients ( aged 20 63 years ) with essential hypertension ( EH ) . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
Plasma Renin Activity ( PRA ) was determined in a group of 50 Cameroonian newborns and 50 Cameroonian children aged 1 15 years under resting conditions in order to establish baseline values , and also to investigate the relationship between PRA distribution , and blood pressure levels , age , or body weight . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
To develop a screening test for identification of renovascular hypertension , the blood pressure and plasma renin concentration responses to an oral test dose of captopril ( 6 . 25 mg ) were studied in 47 hypertensive patients of mean age 61 years ( range 34 85 years ) . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
There was no relationship between responsiveness ( in mmHg / ng / mL ) and patient age and plasma renin activity ; however , responsiveness during chronic treatment was directly correlated with the height of the starting blood pressure and the response to the first dose . . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
This difference in blood pressure at 25 weeks of age was due to reduced total peripheral resistance as determined by microsphere methods , but plasma renin activity and angiotensin 2 concentrations were not different . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
Pretreatment plasma renin ( as an indication of activation of the renin angiotensin system ) and the patient ' s age have been claimed to predict blood pressure fall . ^^^ Emax was not related to age or pretreatment renin , but was positively correlated with pretreatment blood pressure ( r = 0 . 69 ; p less than 0 . 01 ) . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
These characteristics have included physiologic factors , such as sodium sensitivity , plasma renin activity , or sympathetic nervous system activity , as well as demographic components , particularly age and race . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
At 60 weeks of age , rats that received perinatal low salt diet had significantly heavier adrenal glands when compared with the other groups , and the high potassium group had significantly elevated plasma renin concentrations . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
The antihypertensive effect was not related to age , pretreatment plasma renin activity , or serum ionized calcium concentration . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
The preoperative conditions of the patients ( age , duration of hypertension , plasma renin activity , plasma aldosterone concentration , and serum potassium concentration ) , postoperative sequential changes of hormone levels , and outcome of hypertension were compared among the groups in order to determine whether the differences of adrenal pathology would affect the postoperative course . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
The increase in plasma renin activity in response to a graded suprarenal aortic constriction was determined in conscious young ( 6 9 weeks of age ) and adult ( 14 16 weeks of age ) SHR and age matched Wistar Kyoto ( WKY ) control rats . ^^^ Under conditions of relatively little stress , the renin response to reduced renal perfusion pressure was not enhanced in young or adult SHR when compared with age matched WKY rats . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
Chronic monotherapy with calcium antagonists results in an antihypertensive response that is related directly to the patient ' s age and pretreatment blood pressure and indirectly to renin . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
In hypertensive patients , Bmax correlated positively with age ( r = 0 . 639 , p less than 0 . 05 ) and CD 25 ( r = 0 . 593 , p less than 0 . 05 ) and negatively with plasma renin activity ( r = 0 . 679 , p less than 0 . 05 ) , while in normotensive subjects , Bmax correlated with CD 25 only ( r = 0 . 615 , p less than 0 . 05 ) . ^^^ Thus , in patients with essential hypertension , a decrease in cardiac isoproterenol sensitivity and plasma renin activity is associated with an age related increase in antagonist binding capacity . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
In spite of the fact that plasma renin activity declines with age and drugs whose action is mediated via the renin angiotensin system might be expected to be less effective with increasing age , the limited available data suggest that both captopril and enalapril lower blood pressure in the elderly . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
Age as well as renin and black race help to design antihypertensive treatment strategies with better blood pressure control and better well being of the patient . . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
The blood pressure fall was correlated positively with age ( r = 0 . 521 ; p less than 0 . 001 ) and negatively with the rise in heart rate ( r = 0 . 308 ; p less than 0 . 01 ) and renin level ( r = 0 . 205 ; p = 0 . 05 ) . ^^^ After eliminating the linear effects of age by the partial correlation method , blood pressure fall and the initial renin level were no longer correlated ( r = 0 . 046 , NS ) , whereas the positive correlation between age and blood pressure fall persisted after eliminating the effect of renin ( r = 0 . 464 ; p less than 0 . 001 ) . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
Both groups did not differ in age , body weight and height , blood pressure , heart rate , plasma catecholamine levels , plasma renin activity ( PRA ) , and lymphocyte beta 2 adrenoceptor density . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
Biosynthesis of a renin binding protein . ^^^ The biosynthesis of a porcine renin binding protein ( RnBP ) , which specifically binds to renin and forms an inactive high molecular weight renin , was investigated . mRNAs from various porcine tissues were used to investigate in vitro protein synthesis . ^^^ These results strongly indicate that RnBP , present in various mammalian species , is synthesized in renin producing tissues as the mature size and undergoes binding with renin without proteolytic processing . . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
The characteristics of norepinephrine and epinephrine as well as plasma renin activity , angiotensin 2 , aldosterone , vasopressin , and atrial natriuretic factor ( ANF ) were examined in 64 patients ( mean age of 52 + / 16 years ) with dilated cardiomyopathy . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
Responsiveness appears to be related , as well , to pretreatment plasma renin activity and age . ^^^ Thus , the antihypertensive effect is directly related to age and inversely related to plasma renin activity . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
Isoproterenol ( ISO ; 10 ( 8 ) 10 ( 5 ) M ) significantly increased active renin secretion in all age groups ( P less than 0 . 05 ) , with newborns having the highest values at all concentrations . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
Of the 20 patients who had neither had renal surgery nor had end stage renal disease , all had a significantly lower glomerular filtration rate and renal plasma flow and higher diastolic blood pressure , mean arterial blood pressure , plasma renin activity , and serum beta 2 microglobulin concentration than 13 healthy age matched controls . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
The study concerned 8 pts , mean age 55 . 6 + / 7 . 7 years , 1 pt with aldosterone producing adenoma ( APA ) and 7 pts with idiopathic aldosteronism : plasma renin activity ( PRA ) and plasma aldosterone concentration ( PAC ) were respectively 0 . 30 + / 0 . 2 ng / ml / h ) and 314 + / 109 pg / ml . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
Plasma renin activity , active renin concentration and plasma aldosterone concentration were significantly and negatively correlated with age , but not with urinary sodium excretion . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
To evaluate the correlations occurring among plasma atrial natriuretic factor ( ANF ) , renin activity ( PRA ) , aldosterone ( ALD ) and urinary kallikrein ( KK ) in young hypertensives and in young normotensives with or without a family history of hypertension , 26 essential hypertensives ( mean age : 22 . 5 + / 2 ) , 21 normotensives ( mean age : 22 . 3 + / 1 . 9 ) and 13 normotensives with hypertensive heredity ( mean age 22 + / 1 . 8 ) under normal Na+ intake ( 120 mEq / daily ) were studied . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
Neither the acute nor long term responsiveness to doxazosin was related to age , plasma renin activity , plasma noradrenaline or the pretreatment sensitivity to phenylephrine . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
We measured plasma and extracellular fluid volume ( 125I albumin , 51Cr EDTA ) , plasma concentrations of renin , angiotensin 1 and 2 , aldosterone and atrial natriuretic peptide by radio immunoassays in insulin dependent diabetic ( IDDM ) patients with ( n=28 ) and without ( n=11 ) nephropathy and in 14 normal control subjects matched for sex and age . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
Similarly the low renin levels associated with increasing age and with elderly hypertensive patients , may be the result of the elevation of plasma ANP that occurs with aging . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
Plasma atrial natriuretic factor ( ANF ) , blood pressure , age , plasma renin activity and creatinine were measured in 50 normal volunteers , 141 essential hypertensives , 35 patients with chronic renal failure who had never been dialysed and 27 patients with end stage renal failure on constant haemodialysis . ^^^ Plasma ANF was correlated positively with age in the normal group ( r = 0 . 52 , P less than 0 . 01 ) and with blood pressure in the essential hypertensives ( r = 0 . 50 , P less than 0 . 001 ) , and negatively with renin in the normal and end stage renal failure patients ( r = 0 . 47 , r = 0 . 34 ; P less than 0 . 01 , P less than 0 . 05 , respectively ) . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
The antihypertensive efficacy both of angiotensin converting enzyme ( ACE ) inhibitors and thiazide diuretics has been claimed to be influenced by plasma renin activity , which declines with age and is low in blacks . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
Eighteen primary hypertensives ( 12 male , 6 female , mean age 57 . 7 + / 2 . 7 ) were entered in a placebo controlled , double blind crossover study of the effects of equipotent doses of pindolol and propranolol on mean + / SEM systolic BP , diastolic BP , heart rate , active renin ( AR ) , total renin ( TR ) , inactive renin ( IR ) , and % AR / TR . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
Hematocrit , red blood cell mass , plasma volume and plasma renin activity were evaluated in 33 ( 15 women ) young patients with borderline hypertension and in 30 ( 15 women ) age and sex matched normotensive control subjects . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
These results indicate that the total renin content of the plasma does not change , whereas the active renin content decreases with age in normal subjects , and suggest that activation of prorenin to active renin may be impaired in elderly subjects . . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
Although the elderly tend to have low plasma renin levels , the fall in blood pressure after ACE inhibitors is at least as great ( and in several studies greater ) than in younger age groups . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
Of twenty five subjects with high renin essential hypertension ( ten females , 15 males , mean age 30 years ) , 14 were noted to have a decrease in mean arterial blood pressure ( MAP ) when sodium intake was increased from 10 to 100 mmol / d . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
Circulating norepinephrine increased with aging , but a clear cut age related effect was not observed for renin system activity or sodium status . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
Age related changes in glomerular binding of ANG 2 in SHR were not found to be related to changes in either plasma renin activity or systolic blood pressure . . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
However , when blood pressure responders were compared with non responders within the same treatment group , plasma renin activity and PGE 2 excretion rates were higher in the responder group corresponding with younger age in both treatments . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
To evaluate the activity of sympathetic system and of plasm renin in elderly patients with borderline ( BH ) and established essential hypertension ( EH ) , 31 BH mean age 38 years and 30 EH , mean age 39 years ; 15 BH , mean age 66 years , and 15 EH , mean age 68 years , were studied at rest and after dynamic exercise . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
The cardiovascular and endocrine profile of cromakalim has been studied in 8 healthy men ( age 25 + / 2 years : means SEM ) and its influence on renin release from cultured rat juxtaglomerular cells in vitro has also been examined . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
Experiments were performed to determine the effect of veratridine , a substance known to promote norepinephrine release from nerve terminals , on active and inactive renin secretion from renal cortical slices of fetal ( 134 138 days gestation ; term is 145 days ) , newborn ( 4 9 days of age ) , and adult nonpregnant sheep . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
Neither age nor plasma renin activity independently influenced the response to calcium antagonists . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
Our study ; ( 1 ) reports concentrations for active and inactive renin determined by the immunoradiometric assay in normal infants and children ; ( 2 ) confirms , by use of the immunoradiometric assay , the previously described decrease in plasma active and inactive renin , as measured by the enzymatic assay , with increasing age ; and ( 3 ) shows close correlations between the results obtained by immunoradiometric and enzymatic assays for active and inactive renin in normal infants and children . . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
Renin messenger RNA ( mRNA ) levels were compared in the kidneys , livers , brains , adrenals , aortae and hearts of spontaneously hypertensive ( SHR ) and Wistar Kyoto ( WKY ) rats at 5 and 12 weeks of age using a ribonuclease protection technique . 2 . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
Plasma and urine norepinephrine , epinephrine , plasma renin activity and aldosterone were measured in 11 young men ( mean age , 21 years ) with a high blood pressure in the clinic who maintained a high home blood pressure and 12 men with an elevated clinic blood pressure who had a normal home blood pressure . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
This finding , together with the high renin and aldosterone values , indicated a nephrogenic hypertension causing both the cardiomyopathy found at 12 months of age and the endocranial hemorrhage . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
Weanling and young spontaneously hypertensive rats ( SHRs ) demonstrate higher plasma renin activity and plasma aldosterone concentration than age matched normotensive Wistar Kyoto ( WKY ) control rats . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
Based on prevailing hypotheses about the role of renin in essential hypertension , both Laragh and Buhler independently predicted that angiotensin converting enzyme ( ACE ) inhibitors would become less effective with increasing age , as elderly hypertensive patients tend to have low plasma renin activity . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
The groups did not differ with regard to blood pressure and heart rate , age , body weight and height , plasma renin activity and catecholamines , and serum electrolytes and creatinine . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
It is suggested that the sensitivity of the neural control of renin release as well as the arterial baroreflex sensitivity are influenced by age , and possibly the inflexibility of the vascular system . . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
In the untreated patients with essential hypertension ( n = 55 ) , converting enzyme activity was inversely related to mean arterial pressure and age ( r = 0 . 34 , p less than 0 . 01 ) and positively related to plasma renin activity ( r = 0 . 31 , p less than 0 . 05 ) . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
These agents may differ in the relation between the magnitude of their antihypertensive effect and patients ' pretreatment plasma renin activity and age . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
The patient ' s age , gender , race , behavior profile , hemodynamic and neurohumoral status ( plasma renin activity , norepinephrine / epinephrine ratio ) , and quality of life will help determine the choice of antihypertensive agent . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
Antihypertensive treatment according to age , plasma renin and race . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
SBP , heart weight / body weight ratio and plasma renin activity remained unchanged at 39 weeks of age . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
Twelve hypertensive patients ( mean age 46 . 6 years , range 37 55 years ) with fibromuscular dysplasia of the renal artery were treated with percutaneous transluminal renal angioplasty ( PTRA ) and the effects on the renin angiotensin aldosterone system and blood pressure were studied in the acute phase . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
Age , race , blood pressure and renin : predictors for antihypertensive treatment with calcium antagonists . ^^^ Age , race , pretreatment blood pressure and plasma renin activity have been related to the antihypertensive response to calcium antagonists in studies that included 215 patients with mild to moderate essential hypertension . ^^^ In a multiple linear regression analysis of 138 white patients , age , pretreatment blood pressure and renin activity were of independent and significant predictive value for the antihypertensive response . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
Mean arterial pressure changes were inversely correlated with basal renin levels and directly associated with age . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
Atrial natriuretic peptide in hepatic cirrhosis : relation to stage of disease , sympathoadrenal system and renin aldosterone axis . 58 patients ( mean age 51 years ) with cirrhosis of the liver were studied . 16 patients were compensated , 18 decompensated with ascites , and 24 decompensated and treated with diuretics . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
Age , duration of hypertension and renal vein renin ratio seem to be important prognostic factors for the outcome of surgery or PTRA . . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
Combining these data with developmental patterns of plasma renin activity in S / JR rats suggests the possibility that the S / JR rat may become intravascularly volume expanded between 25 and 51 days of age . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
There were no significant differences among the three groups in age , serum protein , albumin , or electrolyte levels , plasma renin activity ( PRA ) , or plasma concentrations of aldosterone and cortisol . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
To assess the role of atrial natriuretic peptide ( ANP ) in relation to the sympathoadrenal and renin angiotensin aldosterone system , and sodium excretion , 88 cirrhotic patients ( mean age 52 years ; 28 compensated , 28 decompensated with ascites , and 32 decompensated and treated with diuretics ) and 26 control subjects were investigated . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
There were no differences between patients with normal hANP levels and patients with hANP levels above normal range regarding age , diabetes duration , metabolic control , kidney function ( creatinine clearance and proteinuria ) , electrolytes , and in plasma renin activity , aldosterone , epinephrine and norepinephrine levels in plasma . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
This study details the efficacy of fosenopril at rest and during exercise on blood pressure , plasma potassium , plasma renin activity , and plasma aldosterone in 11 hypertensive males , mean age 55 years . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
Cure or improvement was noted more often in patients with fibromuscular dysplasia , short history of hypertension , pathologic renin quotient , normal total hippuric acid clearance , or age under 40 years . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NT and EH groups were similar with respect to age and basal levels of renin , aldosterone and ANP ( 34 . 5 + / 5 . 5 in NT and 32 . 5 + / 6 . 3 pg / ml in EH , mean + / sem ) . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NT and HT groups were similar with respect to age and basal levels of renin , aldosterone and ANP ( 34 . 5 + / 5 . 5 in NT and 32 . 5 + / 6 . 3 pg / ml in HT , mean + / SE ) . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
Atrial natriuretic factor , digoxin like immunoreactive substance , and plasma renin activity were unrelated to umbilical vessel source or gestational age . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
The relationship between plasma atrial natriuretic factor ( ANF ) , blood pressure ( BP ) , age , plasma renin activity ( PRA ) and urinary sodium excretion was studied in 64 normal subjects ( mean age 48 . 7 + / 2 . 1 yrs ; BP : 126 . 5 + / 1 . 6 / 79 . 5 + / 0 . 9 mmHg ) and in 104 untreated uncomplicated essential hypertensives ( 50 . 8 + / 1 . 1 yrs ; BP : 164 . 7 + / 1 . 6 / 105 . 2 + / 0 . 6 mmHg ) . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
These characteristics include age , sex , race , therapy , stage of hypertension , sodium intake , renal function , and renin status . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
The decrease in blood pressure with calcium antagonists was directly correlated with the patient ' s age and inversely with the pretreatment plasma renin activity . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
The plasma potassium reduction could not be predicted by age , plasma renin activity , plasma and urinary aldosterone or urinary kallikrein . ( ABSTRACT TRUNCATED AT 250 WORDS ) . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
In a study of 38 fetuses total kidney renin was significantly correlated with gestational age ( r = 0 . 63 ) . ^^^ Although whole fetal kidney renin specific activity was found to decrease with gestational age ( r = 0 . 65 ) , the mean value of the specific activity was about 20 times greater than in normal adult cortex and double that in tissue from patients with renal artery stenosis , suggesting renin angiotensin system hyperactivity . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
The age related changes in the renin angiotensin system were investigated in normotensive 3 , 10 , 20 , and 30 mo old female Wistar rats . ^^^ Plasma renin concentration and immunofluorescent renal renin index remained constant from 3 to 10 mo , then decreased as the animals become older , whereas plasma concentration of renin substrate diminished slightly between 10 and 20 mo and plasma converting enzyme activity was not modified with age . ^^^ These results indicate that the activity of the renin angiotensin system is progressively reduced with age and suggest that angiotensin 2 does not play an important role in the maintenance of blood pressure and kidney hemodynamics in normotensive female senescent rats . . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
Changes in arterial pressure were unrelated to age , plasma ionized calcium , parathyroid hormone ( PTH ) , plasma renin activity ( PRA ) , plasma aldosterone , 24 h urinary calcium , sodium and potassium and were only weakly related to body weight . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
Possible factors influencing response include drug dose , plasma drug concentration , plasma renin activity , baseline blood pressure , nonionized calcium in blood and inside vascular smooth muscle cells , patient age and patient race . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
We studied 108 subjects ( age range , 4 to 76 years ) to determine the effect of age on prorenin ( inactive renin ) , active renin , and plasma renin activity in normal children , adolescents , and adults . ^^^ Prorenin concentrations were positively correlated with age over the range of 4 to 76 years , while plasma renin activity and active renin concentration were negatively correlated with age . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
The current investigation was performed to determine whether there are changes in the renin angiotensin system with increasing age in rats . ^^^ There were no changes in plasma renin activity or angiotensin 2 concentrations , but the number of angiotensin 2 binding sites in isolated glomeruli increased with increasing age ( r = 0 . 87 , P less than 0 . 01 ) . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
The effects of dietary sodium upon serum and urinary calcium and selected vitamin D metabolites were studied in two groups ( n = 10 each ) of age and gender matched , white normotensive subjects and patients with normal renin hypertension . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
Glomerular filtration rate , renal plasma flow , active renin , renin substrate and angiotensin 2 concentrations were monitored in nine consecutive patients ( 3 women , 6 men , mean age 31 years ) with newly diagnosed , insulin dependent diabetes . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
To evaluate the activity of the sympathetic system and of plasma renin in elderly patients with borderline and established essential hypertension , 31 borderline hypertensives aged less than 60 years ( mean age 38 years ) , 30 established essential hypertensives aged less than 60 years ( mean age 39 years ) , 15 borderline hypertensives aged greater than 60 years ( mean age 66 years ) and 15 essential hypertensives aged greater than 60 years ( mean age 68 years ) were studied at rest and after dynamic exercise . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
Vol . 21 , pp . 63 75 ) we showed that thirst elicited by activation of the brain ' s renin angiotensin system in the suckling becomes specific to water after 16 days of age . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
The pharmacokinetics of ramipril , a new potent long acting non sulphydryl converting enzyme inhibitor , and its effects on blood pressure , plasma renin activity and angiotensin 2 concentrations were studied in a group of 8 elderly volunteers ( mean age 77 , range 61 to 84 ) . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
No significant difference between these two groups was observed with respect to systolic pressure , age , sex , plasma potassium , plasma renin activity and plasma aldosterone levels . ( ABSTRACT TRUNCATED AT 250 WORDS ) . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
The captopril treated rats had a significant elevation in serum renin activity at 12 weeks of age indicating the presence of chronic converting enzyme inhibition , and the 6 OHDA treatment resulted in a depletion of hypothalamic ( 86 % ) and brainstem ( 76 % ) norepinephrine content . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
Plasma renin activity ( PRA ) , aldosterone ( aldo ) levels , electrolyte levels , and blood pressures were measured in 16 patients with affective disorders taking lithium prophylactically , and in 16 age and sex matched control subjects . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
When plasma renin activity is measured in the infant with renal failure of hypertension , one must compare the result with the normal range of values related to postnatal age of normal infants . . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
Significant reductions in kinin excretion were noted in the patients with liver disease which could not be accounted for by differences in age , plasma renin , aldosterone excretion or sodium excretion . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
This antihypertensive effect was related directly to the height of pretreatment arterial pressure ( r = 0 . 67 , p = 0 . 006 ) but not to age or pretreatment plasma renin activity . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
Plasma renin activity was measured at 11 and 16 weeks of age . 2 . ^^^ Plasma renin activity was negatively correlated with both glomerular filtration rate and renal blood flow , but the relationship was stronger at 11 than at 16 weeks of age . 3 . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
In a cross sectional analysis , plasma renin activity , renin concentration and aldosterone concentration showed no relationship with age . ^^^ From these cross sectional and longitudinal observations we conclude that beyond the age of 60 ageing has no detectable effect on plasma renin and aldosterone levels in these elderly hypertensive patients . . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
The arterial blood pressure ( BP ) , the ratio between gram myocardial mass per 100 g body mass ( R ) , the plasma renin activity ( PRA ) and the aldosteron content in the blood plasma ( PA ) were investigated in a model of renal hypertension , 30 days after the operation , in the following groups of male Wistar rats : operated and treated throughout the entire experimental period with captopril Pharmachim in a dose of 30 mg / kg body mass twice daily orally , and two control groups operated and treated with saline , and non operated animals of the same age , treated only with saline . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
Glandular renin levels are higher in the neonatal period than at 2 3 weeks of age , and then rise dramatically with the onset of puberty . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
Chronically catheterized fetal lambs ( n = 11 , gestational age 111 139 days ) and neonatal lambs ( n = 20 , postnatal age 4 30 days ) were studied to explore during development the relationship of renal hemodynamic responses during hypoxemia to plasma epinephrine concentration ( E ) , plasma norepinephrine concentration ( NE ) , plasma arginine vasopressin concentration ( AVP ) , and plasma renin activity ( PRA ) . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
Blood pressure , both venous and urinary catecholamines and plasma renin activity ( PRA ) were studied in 10 patients ( 6 men and 4 women , mean age 70 + / 10 years ) on the first three days after cerebral infarction . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
These results suggest that a considerable relationship exists between intracellular sodium and free calcium in lymphocytes and that , in essential hypertension , the alteration in cellular metabolism of sodium and calcium may be linked to the renin system but not to blood pressure , age , or adrenergic activity . . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
Blood pressure , plasma renin activity and the concentrations of aldosterone and cholesterol in plasma and sodium and potassium in urine ( 48 h collections ) and nutrient intakes were determined in 22 vegans ( 11 male and 11 female ) and omnivore controls matched for age , sex and body build . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
Renin administered into the preoptic area at 105 days of age caused an increase in salt intake , but the increase was markedly inhibited by the oral administration of taurine as well . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
Statistically significant changes were found in plasma renin activity ( P less than . 001 ) and plasma aldosterone ( P less than . 001 ) when the hypertensive patients were divided into two age groups , those under 45 and those over 45 . ^^^ These changes were not found in the normal subjects in the same age groups , indicating that age is an important influence on the renin aldosterone system in hypertensive patients , and leads to variations in this hormonal axis similar to those observed in normal elderly subjects . . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
Beginning at 3 5 days of age , renin increased ingestion of milk and water off dam . ^^^ After 15 days of age , milk ingestion off dam was no longer increased by renin , but intake of water continued to be evoked . ^^^ In contrast , renin did not increase intake by suckling at any age . ^^^ These findings reveal that the adult characteristics of the dipsogenic action of the renin angiotensin system in the brain emerge at 15 days , at which age the increased intake becomes entirely specific for water . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
The N induced changes in supine systolic and diastolic pressure correlated ( p less than 0 . 05 ) with age ( r = 0 . 65 and r = 0 . 58 , respectively ) and pretreatment plasma renin activity ( r = 0 . 71 ) . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
Effect of age on the renin angiotensin aldosterone system in normal subjects : simultaneous measurement of active and inactive renin , renin substrate , and aldosterone in plasma . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
These groups could not be distinguished on the basis of sex , age , or pretreatment plasma renin activity . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
Serum renin activity ( SRA ) also increased in both strains receiving PEG at 6 and 8 wk of age , but the response was suppressed in the SHR relative to the WKY ( P less than 0 . 001 ) . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
To clarify age related changes in the plasma renin activity ( PRA ) aldosterone ( ALDO ) system in relation to urinary sodium ( Na ) excretion in pseudohypoaldosteronism type 1 ( PHA ) , we followed a patient with PHA serially by measuring the hormonal balance and urinary electrolyte excretion for 5 years . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
Blood pressure tended to be higher in the former ( 121 / 78 + / 9 / 8 ( s . d . ) versus 113 / 74 + / 11 / 9 mmHg ; P less than 0 . 005 ) ; mean age , urinary sodium or potassium excretion , plasma sodium , potassium , renin activity or aldosterone levels and creatinine clearance were comparable . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
The two study groups had a similar mean age ( 24 + / 2 ( SD ) yr ) , body weight , blood pressure ( 112 / 64 + / 10 / 7 mmHg ) , heart rate , plasma and urinary sodium and potassium , and plasma norepinephrine , epinephrine , angiotensin 2 , renin and aldosterone levels . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
Blood pressure , pulse rate ( PR ) , serum osmolality and electrolytes , as well as plasma vasopressin ( PVP ) and plasma renin activity ( PRA ) , were measured in five men and two women [ mean age 38 . 6 + / 3 . 9 ( SE ) yr ] before , during , and after inflation of an antigravity suit that covered the legs and abdomen . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
Further difficulties in comparing one trial with another include differences with respect to age , race , severity of hypertension and renin status in the patient populations under investigation , since all these factors may influence responsiveness to therapy with both classes of agent . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
Chronic monotherapy with a calcium antagonist results in an antihypertensive response , which is directly related to the patient ' s age and pretreatment BP and indirectly related to plasma renin levels . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
Plasma renin activity was inversely correlated with age , but was not related to the reduction of SBP or DBP . ( ABSTRACT TRUNCATED AT 250 WORDS ) . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
Furthermore , when the activity of the plasma renin system decreases with advancing age , increased activity of a local angiotensin system may contribute to the regulation of vascular tone . . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
The ratios did not correlate with patient age or plasma renin level . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
To clarify the pathogenesis of this hypertension we examined the blood pressure ( BP ) behaviour and the renin angiotensin aldosterone system in 31 TS patients ( 2 22 years of age ) . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
Plasma renin activity rose significantly in all cases whereas plasma aldosterone dropped and reached normal levels for age . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
Evaluation of an aldosterone radioimmunoassay : the renin angiotensin aldosterone axis as a function of sex and age . ^^^ Measurement of plasma aldosterone and plasma renin activity in these subjects showed that both these parameters are higher in subjects under 40 years of age than in those over 40 . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
Multiple regression analysis revealed that urinary potassium excretion was influenced by age , race , sex , body weight , blood pressure , creatinine clearance , renin , and aldosterone . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
We report a patient who presented in 1974 at age 15 yr with blood pressure of 240 / 120 mm Hg , serum K of 3 . 1 mM , low renin , and high normal aldosterone excretion , with findings diagnostic of GSH . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
Adrenal ZG renin was significantly decreased in S as compared with R rats even at 6 weeks of age , when both S and R rats are still normotensive ( S = 7 . 2 + / 0 . 2 , R = 18 . 0 + / 1 . 6 ng angiotensin I / mg protein / hr ) . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
To investigate this possibility we measured plasma renin activity ( PRA ) in 23 patients ( 17 male , 6 female , age 41 70 ) with New York Heart Association stage 3 heart failure due to ischaemic heart disease in a placebo controlled trial over one month . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
Age and renin status do not reliably predict sodium sensitivity . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
Renin relationship to sex , race and age in a normotensive population . ^^^ The relationship of renin activity to sex , race ( black or white ) and age ( less than 50 or greater than or equal to 50 years of age ) was examined in 236 normal subjects measure yearly for up to 9 years . ^^^ However , the sex and race differences primarily occurred as a consequence of a lack of decline in renin activity with age among white men . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
Plasma renin activity was lower in 13 mothers with small for gestational age ( SGA ) infants ( 5 . 2 + / 0 . 89 ng / ml per h , compared with 13 mothers with appropriate for gestational age ( AGA ) infants ( 16 . 65 + / 2 . 37 ng / ml per h , P less than 0 . 001 . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
There were no significant differences between the 3 groups with respect to age , ideal body weight , supine resting mean blood pressure , serum creatinine , daily urinary excretion of sodium , or renin substrate at the time of study . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
The values for plasma renin substrate concentration are similar to those reported for younger age groups . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
Plasma renin activity decreased with age in NC but remained elevated in LC . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
The prognosis of hypertension was evaluated pre operatively in 40 patients with primary aldosteronism owing to adenoma by examining the severity of hypertension , family history of hypertension , age of the patients , duration of hypertension , plasma renin activity , plasma aldosterone concentration , and efficacy of spironolactone ( 100 mg per day for 10 days ) on blood pressure . ^^^ There were no significant differences in the age of the patients , family history of hypertension , plasma renin activity or plasma aldosterone concentration between these two groups . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
The predictive value of the duration of arterial hypertension , patient ' s age , plasma renin activity coefficient and quantitative intrarenal flow data obtained at angiography with a simultaneous droperidol test , was determined . ^^^ Predictive use of other parameters , such as the duration of arterial hypertension , patient ' s age , plasma renin activity coefficient yielded higher rates of false positive and false negative results . . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
A newly standardized projective test of reactions to frustration , a questionnaire related to such characteristics as aggressiveness and dominance , and a standardized interview were applied to 16 patients with established high renin essential hypertension and 21 patients of similar age with normal renin . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
Renal cortical high molecular weight renin ( Mw : 60 , 000 ) of the dog is a complex of renin ( low molecular weight renin ; Mw : 40 , 000 ) and a renin binding protein . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
In the controls , the level of plasma inactive renin increased slightly with age but was never above 50 ng per milliliter per hour . ^^^ In young diabetic patients studied within three years of the onset of diabetes the concentration of inactive renin was normal , and in some older diabetics without complications it remained within the age adjusted normal range for many years . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
The relationships between arterial pressure ( BP ) and plasma vasopressin levels , plasma renin activity , and other variables were determined in 96 untreated essential hypertensive men ( 146 / 100 mm Hg ) and women ( 153 / 102 mm Hg ) whose average age was 44 years , 80 normal men and women ( 121 / 79 mm Hg ; mean age , 47 + / 2 years ) , and 40 subjects defined as borderline hypertensive . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
Thus , age is a variable with a substantial effect on plasma concentrations of vasopressin in addition to the well known effect on renin and noradrenaline . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
The rise in renin was inversely related to age . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
Sodium and renin profiles based on race and age ] . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
Changes in reactivity of the renin angiotensin aldosterone system in old age as a risk factor in the development of hypertension ] . ^^^ The sensitivity of the renin angiotensin aldosterone system ( RAAS ) to regulatory sympathoadrenal and hypothalamo pituitary effects was shown to increase with advancing age , in spite of declining plasma renin and aldosterone baselines . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
Plasma renin activity ( PRA ) and systemic and forearm hemodynamics were studied during acute changes in cardiopulmonary blood volume and central venous pressure in 20 subjects , including 9 normotensive controls and 11 essential hypertensive patients of the same age . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
We studied plasma renin activity and concentration , and factors involved in their control ( age , blood pressure , and sodium excretion ) in 40 healthy subjects ( group 1 ) , 18 patients with type 1 diabetes without complications ( group 2 ) , and 31 with type 1 diabetes with proliferative retinopathy ( group 3 ) . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
Moreover , the possible interrelationships between urinary kallikrein excretion and age , sex , electrolyte excretion , and plasma renin activity were examined . ^^^ In these patients the enzyme was weakly and positively related to urinary potassium and plasma renin activity ; no correlation was found with blood pressure , urinary sodium , age , or sex . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
Circadian rhythms of plasma renin activity and aldosterone : changes related to age , sex , recumbency and sodium restriction . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
A study on renin binding protein ( RnBP ) in the human kidney . ^^^ We purified , from human kidney , a protein that reacts with rabbit anti porcine kidney renin binding protein ( RnBP ) antiserum by trapping with porcine kidney renin . ^^^ The latter two kinds of protein were identified as the porcine renin and human kidney protein from their electrophoretic mobilities and reactivity toward rabbit anti porcine kidney renin and RnBP antisera . ^^^ Therefore , it is suggested from the reactivity toward the anti porcine RnBP antiserum and inhibitory action toward porcine renin that the human kidney protein is RnBP and that the human RnBP is purified as a complex with porcine renin . . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
Differences in renin and aldosterone could not be explained by age , natriuresis or plasma volume . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
The pattern of response to postural changes of blood pressure ( BP ) , plasma renin activity ( PRA ) and plasma aldosterone concentration ( PAC ) was investigated in 11 patients with renal mobility and without treatment and compared with that of an age and sex matched group of untreated hypertensives without renal mobility . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
Influence of age and sex and of castration on renin substrate of normal and nephrectomized rats . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
Relation of age , diastolic pressure and known duration of hypertension to presence of low renin essential hypertension . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
Age dependence of the response of blood pressure , heart rate and plasma renin activity to captopril in essential hypertension ] . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
P . ) , pulse rate , several hormones [ plasma renin activity ( PRA ) , plasma aldosterone ( PA ) , ACTH , plasma cortisol ( PC ) , urinary catecholamines and urinary aldosterone ] and urinary electrolytes were investigated in 9 male patients with essential hypertension [ mean age 36 . 2 + / 4 . 1 ( S . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
A 19 year old female , known to have had hypertension and hypokalemic alkalosis since the age of 9 months , was found to have suppressed renin , negligible plasma and urinary aldosterone and low plasma levels of other known sodium retaining steroids . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
Effect of age on diagnostic usefulness of stimulated plasma renin activity and saralasin test in detection of renovascular hypertension . ^^^ The diagnostic usefulness of the timed intravenous pyelogram ( IVP ) , isotopic renal flow study ( renal flow ) , stimulated plasma renin activity ( SPRA ) , saralasin infusion test , and renal vein renins ( RVR ) in detecting possible renal vascular hypertension was studied in relation to age . ^^^ The results indicate an increasing usefulness with age of a high SPRA or a positive saralasin test in indicating an abnormal renal 10 ray and an abnormal renal vein renin ratio , and thus a potentially correctable lesion . . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
Role of renin profile and age in the choice of the therapeutic approach of arterial hypertension ( author ' s transl ) ] . ^^^ In conclusion our data indicate that age must be taken into account in classifying hypertensive patients in renin subgroups . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
Renin measurements serve as an endocrine marker for the activity and reactivity of the sympathetic nervous system reflecting a beta adrenoceptor mediated response which tends to decrease with older age . ^^^ As lower renin and as older the age diuretic agents and calcium antagonists are more effective , the hyporesponsive renin being a co determinant of pressure response in these patients . . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
Patients with a high renin value and usually younger age respond better to drugs that interfere with the renin angiotensin system , that is , beta blockers or converting enzyme inhibitors . ^^^ Patients with a low renin value and often older age respond better to calcium entry blockers or diuretics . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
The antihypertensive efficacy of the calcium entry blocker nitrendipine administered as monotherapy ( 20 80 mg ; mean , 36 / day ) on the average for 144 days to 46 patients with essential hypertension ( WHO 1 and 2 ) was investigated in relation to age , pretreatment blood pressure , and plasma renin activity . ^^^ The fall in mean blood pressure after nitrendipine was directly related to age ( r = 0 . 553 ; p less than 0 . 001 ) and pretreatment mean blood pressure ( r = 0 . 470 ; p less than 0 . 01 ) and inversely related to plasma renin activity ( r = 0 . 558 ; p less than 0 . 001 ) . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
No correlation was found between pump inhibition and age , sex , blood pressure , levels of plasma K+ or Na+ , or plasma renin activity . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
In future studies on hypertensive humans we should pay more attention to the characteristics of the patients ( sex , race , age , drug therapy , stage of hypertension , sodium intake , renal function , and renin status ) and make a more vigorous effort to match these patients properly with normotensive control subjects . . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
No significant difference was found between the latter two groups in regard to age , sex , weight , etiology of hypertension , pretreatment ECG voltage , blood pressure , plasma renin activity , duration of treatment and duration of maintained blood pressure control . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
Plasma renin activity , 11 deoxycorticosterone , corticosterone and aldosterone levels were all increased several fold over the normal range for age , thus excluding an adrenal biosynthetic defect . ^^^ However at 3 1 / 2 years of age , plasma renin activity and aldosterone were still markedly elevated while precursor steroids were normal and the clinical condition satisfactory . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
The purpose of this investigation was to correlate the development of the various enzyme activities associated with the renin angiotensin system with age related differences in the steady state concentrations of angiotensin 1 ( AI ) and 2 ( AII ) . ^^^ Plasma renin activity and concentration increased between birth and 3 wk of age , and declined thereafter to adult values . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
An inverse relationship between plasma renin , aldosterone and age has been demonstrated . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
The antihypertensive effects of the calcium antagonists were directly related to the patient ' s age , pretreatment blood pressure but indirectly to pretreatment renin . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
Renin was not detected in any cell at any age . . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
The antihypertensive efficacy of the calcium antagonist verapamil was tested in 43 patients with essential hypertension , examining relationships between age and pretreatment renin and blood pressure and comparing intraindividually the responses with those obtained using beta blockers ( n = 29 ) and diuretic therapy ( n = 18 ) . ^^^ Verapamil produced a decrease in mean blood pressure that was directly related to the patient ' s age and pretreatment blood pressure but inversely to pretreatment renin . ^^^ Although there was no difference in overall pressure response between verapamil , beta blocker , and diuretic therapy , the pressure responses with diuretics paralleled those obtained with verapamil , whereas , in contrast , responses with beta blockers correlated indirectly with the patient ' s age and directly with pretreatment renin . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
Blood pressure , exchangeable sodium content , sodium metabolic balance , and plasma concentrations of active renin , angiotensin 2 , and aldosterone were measured in seven normal men and 10 essential hypertensive men of similar age and weight . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
Changes in renal plasma flow correlated inversely with age and final mean arterial pressure and correlated positively with initial plasma renin activity of subjects . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
Recent findings concerning tonin , a serine protease , are described : a ) 80 % of its amino acid sequence , b ) its different characteristics from other serine proteases , from renin , cathepsin D and the angiotensin 1 converting enzyme , c ) the activation of inactive renin , d ) its involvement in the 1K 1C hypertensive rats , e ) the demonstration of its presence in the distal tubular cells of the rat kidney , and finally , f ) its presence in urine and the influence of age and of sodium intake on its urinary excretion . . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
There was no significant difference between the two groups as regards age , preoperative BP level , plasma renin activity , blood volume , or response to [ Sar 1 , Thr 8 ] A 2 . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
Purification of high molecular weight ( HMW ) renin from porcine kidney and direct evidence that the HMW renin is a complex of renin with renin binding protein ( RnBP ) . ^^^ Sodium dodecyl sulfate polyacrylamide gel electrophoresis of the HMW renin showed two protein bands , of which one was identified as renin from the electrophoretic mobility and the other was the protein , assigned as renin binding protein ( RnBP ) , that was insolubilized by acidification . ^^^ The purified HMW renin is a complex of renin with RnBP , and the molecular weights of RnBP and renin in the HMW renin were estimated to be 39 , 000 and 32 , 000 , respectively , by gel permeation liquid chromatography in 6 M guanidine HCl . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
In hypertensives this age dependent beta receptor related effect tends to be enhanced as judged from the greater reduction of cardiac isoproterenol sensitivity and the blunted renin response to exercise stimulation . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
The ability of plasma to stimulate G6PD was inversely correlated with plasma renin activity in the hypertensive patients and increased with age and sodium intake in the normotensive subjects . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
Plasma renin activity was significantly elevated ( p less than 0 . 001 ) at 48 72 h and urinary epinephrine levels were significantly lower ( p less than 0 . 05 ) at 24 48 h of age in the drug group , and norepinephrine levels were equivalent . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
Renin was present in all brain regions studied and decreased with the age of the animals . ^^^ An increased activity of renin was measured in several nuclei of the brain stem and in the neurohypophysis of young hypertensive rats when compared with age matched normotensive control animals . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
The renin angiotensin system was examined in Fischer rats at 7 , 11 and 14 days after Leydig cell tumour transplantation , and in age matched controls . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
Plasma aldosterone concentration was markedly elevated , and plasma renin activity was similar to or higher than that reported in normal infants of comparable age . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
Multiple regression analysis showed that the addition of age and plasma renin activity made little effect . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
Superficial cortical and juxtamedullary glomeruli were obtained from animals at 1 , 2 , and 4 wk of age and from adults to determine renin concentration . ^^^ Superficial cortical glomerular renin concentration at 1 wk of age averaged 7 . 7 + / 1 . 6 ( S . ^^^ Total renal renin concentration increased with age and showed a significant positive correlation with the concomitant increase in kidney weight . ^^^ But renal renin content increased more than kidney weight between 1 2 wk of age . . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
Gestational age was inversely correlated with plasma ritodrine concentration , plasma renin activity , and urinary arginine vasopressin excretion . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
In 40 male patients with essential hypertension less than the age of 36 years , the plasma prolactin ( PRL ) , plasma renin activity ( PRA ) and plasma catecholamines ( noradrenaline ( NA ) and adrenaline ( A ) ) were determined simultaneously . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
Plasma renin concentration ( PRC ) , activity ( PRA ) and substrate concentration ( PRSC ) were measured in 27 males and 31 female children aged 3 days to 14 . 5 years ( median age 10 months ) . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
Relationship with age and plasma renin activity . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
Relationships between age , pretreatment blood pressure , pretreatment plasma renin activity , and hypotensive response were examined . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
In order to observe alterations of the Renin Angiotensin Aldosterone ( RAA ) system in elderly individuals , 40 healthy Venezuelan mestizos ( 8 men , 32 women ) over 60 years of age were examined . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
Central and forearm arterial and venous hemodynamics , arterial baroreflex sensitivity , plasma renin activity , and catecholamines were studied in supine position and after 10 degrees head down tilt in 29 patients with sustained essential hypertension and in 29 normotensive controls of the same age and sex . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
The influence of age on the activity of the renin angiotensin system in rats with adrenal regeneration hypertension . ^^^ The changes of plasma concentration of renin ( PRC ) , and its substrate ( RSC ) and renal renin activity ( RRA ) , considered as an indicator of the secretory activity of the regenerating adrenal were studied 5 , 10 , 20 , 40 and 60 days after the adrenal enucleation to look for possible age differences related to the higher susceptibility of immature rats to the hypertensive influence of the regenerating adrenal . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
The hypotensive action of the angiotensin converting enzyme inhibitor captopril was investigated in 13 hypertensive patients in relation to their age , body weight , the pretreatment level of plasma renin activity ( PRA ) , serum creatinine concentration and suppression of angiotensin 2 ( PA 2 ) by captopril . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
Parameters such as age , sex , blood pressure , plasma renin activity , and plasma aldosterone concentration were also examined in 2 groups of essential hypertensive patients , divided on the basis of their Na+ / K+ net fluxes . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
Relationships between plasma catecholamines , renin , age and blood pressure in essential hypertension . ^^^ The aim of this study was to examine the interrelationships between age , plasma catecholamines , plasma renin activity ( PRA ) and blood pressure in essential hypertensive ( EH ) patients . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
The study also disclosed age specific changes of the renin activity in blood plasma and renal cortical tissue ; with age it tended to decline both in plasma and kidneys . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
The incidence of disorders in renin secretion is different in relation to sex , age and duration of hypertension . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
In normotensive pregnant women ( n = 26 ) there was a rise in all components of the RAAS measured : plasma renin activity ( PRA ) , plasma aldosterone concentration ( PAC ) and urinary aldosterone excretion ( tU Aldo ) , from week 12 to week 20 of pregnancy , compared with non pregnant control subjects ( n = 24 ) of similar age . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
Nyctohemeral values of plasma renin and aldosterone in relation to age , sex and sodium intake and posture ] . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
Possible factors involved in the control of plasma renin activity ( PRA ) and concentration ( PRC ) have been analysed in 49 patients with long standing Type 1 diabetes and in 40 healthy controls matched for age and sex . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
Urinary excretion of kallikrein ( UKal ) , sodium , potassium , protein , and creatinine , as well as the kidney content of kallikrein and renin , was studied in spontaneously hypertensive FH / Wjd ( FH ) male and female rats and in age and sex matched normal Wistar rats . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
The effect of age on the renin angiotensin aldosterone systems and other physiological variables in normal subjects . ^^^ The influence of age on the renin angiotensin aldosterone ( RAA ) system in 125 normal subjects , ages ranging from 13 90 , in Valencia , Venezuela , was evaluated . ^^^ A highly significant inverse correlation was found between age and stimulated plasma renin activity ( r = 0 . 7149 , p less than 0 . 001 ) , and between age and urinary aldosterone ( r = 0 . 4837 , p less than 0 . 001 ) . ^^^ Plasma renin presented an appreciable percentage of decrease when compared to the highest levels found in the lowest age group ; plasma renin decreased 80 % , while urinary aldosterone decreased only 40 % between ages 80 and 90 . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
In several clinical studies , the decrease in blood pressure following the administration of calcium channel entry blockers was directly correlated to the patient ' s age and pretreatment blood pressure , and indirectly to the pretreatment plasma renin activity . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
Relationships with age , blood pressure , exchangeable sodium , renin , aldosterone and catecholamines . ^^^ The two study groups did not differ in age , sodium and potassium metabolism , and plasma levels of renin , aldosterone and norepinephrine , while plasma epinephrine was slightly higher in essential hypertension . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
Interrelations between systemic arterial pressure , extracellular fluid ( ECF ) volume , exchangeable sodium ( Na ) and the renin angiotensin aldosterone system were studied in 38 young patients with borderline hypertension and in 37 age and sex matched control subjects . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
Basal and ambulant plasma renin activity ( PRA ) were measured in 12 insulin dependent diabetics ( IDDS ) with elevated glomerular filtration rate ( GFR ) , 12 IDDs with normal GFR matched for age , sex and duration of diabetes and 12 age and sex matched non diabetic control subjects . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
This study examines the influence of posture on plasma prolactin , plasma catecholamines , plasma renin activity , blood pressure and heart rate in 24 patients with borderline hypertension ( age 19 + / 1 years ) and 20 normotensive subjects matched for age and body mass index . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
Blood pressure , plethysmographically determined muscle blood flow in the calf at rest and during maximal dilatation , plasma renin activity , angiotensin 2 and plasma and urinary aldosterone were determined in normotensive men with a positive family history of hypertension ( n = 17 ) and in an age and weight matched control group ( n = 15 ) during usual sodium intake and after four weeks of increased salt intake . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
We conclude that the high renin levels at young age contribute to the basal arterial pressure in puppies . . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
Plasma renin activity remained unchanged at 37 weeks of age though the treatment was effective . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
A significant ( P less than 0 . 001 ) age related decrease for active ( r = 0 . 60 ) , inactive ( r = 0 . 59 ) and total renin concentration ( r = 0 . 66 ) was observed . ^^^ After correction for the influence of age , active renin concentration correlated with plasma renin activity ( r = 0 . 81 ) , but not with inactive renin concentration ( r = 0 . 18 ) . ^^^ The proportions of active and inactive renin were not related to age , and the overall percentage of inactive renin was 79 % . . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
Infants with HA had extremely elevated plasma renin activity ( PRA ; 70 650 ng angiotensin 1 / ml 10 h ) , which gradually decreased with age , and PRA was normal in adults . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
Antihypertensive responses correlated directly with pretreatment blood pressure ( p less than 0 . 001 ) and the patient ' s age ( p less than 0 . 01 ) , and indirectly with plasma renin activity ( p less than 0 . 01 ) . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
The present study was designed , therefore , to determine the effects of 6 oxo PGE 1 on blood pressure ( BP ) , the renin angiotensin aldosterone system and platelet aggregability in man . 6 healthy male volunteers ( mean age : 24 . 3 + / 1 . 2 years ) and one patient with Shy Drager syndrome ( a 57 year old female ) were studied . 6 oxo PGE 1 , dissolved in physiological saline , was infused intravenously at three different doses of 7 . 5 , 15 and 30 ng / kg / min , for 15 min each . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
Blood pressure , heart rate , plasma renin activity , adrenaline and noradrenaline concentrations , and plasma or urinary electrolyte estimations did not differ significantly between two groups of normotensive subjects matched for age and sex with and without a family history of hypertension . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
In a comparison of the age matched NT , normal renin EHT ( NRH ) and low renin EHT ( LRH ) , the mean value of PNA in NRH was significantly higher than that in NT ( p less than 0 . 001 ) and LRH ( p less than 0 . 001 ) . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
Of 103 borderline essential hypertensives below the age of 36 years , 11 ( 10 . 7 % ) showed low renin , 57 ( 55 . 4 % ) showed normal renin , and 35 ( 33 . 9 % ) showed high renin . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
This study investigated the changes in circadian rhythms of plasma renin activity ( PRA ) and plasma aldosterone ( PA ) which occur in essential mesor hypertensive women , increasing in age . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
No correlation was found between PRA , PAC and serum potassium in cord blood and in 2 to 6 day old infants , but there was a significant correlation between the parameters ( r = 0 . 72 and p less than 0 . 02 ) in 12 to 22 day old infants , indicating that at this age , as in healthy adults , the renin angiotensin system and serum potassium seem to be the major stimuli for aldosterone secretion . . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
Direct and indirect measurement of urinary kallikrein excretion in patients with essential hypertension and normotensives : relation to age and plasma renin and aldosterone levels . ^^^ The relevance of age and activity of the renin angiotensin aldosterone system to the excretion of urinary kallikrein ( Ukal ) was studied in twenty five patients with essential hypertension and forty normotensive controls . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
Awake blood pressure variability , age , resting plasma renin activity and resting plasma noradrenaline levels did not have a significant correlation with left ventricular mass index . 3 . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
Activation of the renin angiotensin system may in part be responsible for the abnormally increased vascular tone which occurs in heart failure ; it has also been suggested that this system ' s responsiveness may diminish with age . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
Differences in renin activity and differences in aldosterone renin ratio could not be explained by differences in age , duration of hypertension and sex ratios . ^^^ These differences and the difference in renin activity between patients with high and patients with medium renin essential hypertension could not be explained by differences in age and / or sex ratio between the two subgroups . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
Renin angiotensin aldosterone system with regard to age ] . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
Properties of renin binding protein . ^^^ Hog renal renin binding protein could bind homologous and non homologous renin but could not bind human renal renin . ^^^ Renin binding protein was only detected in the kidney and pituitary in which renin is found in relatively high concentration . ^^^ Most renin binding protein was recovered in the cytosol fraction and was not associated with sedimentable subcellular organelles . ^^^ A renin secreting tumor ( Juxtaglomerular cell tumor ) in human kidney produced not only renin but also renin binding protein in a very large quantity . . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
Specific distribution of renin binding protein in rat and dog kidney . ^^^ Localization of renin binding protein in the renal cortex of the rat and dog was investigated . ^^^ These results indicate that the renin binding protein is located in the tubules of the cortex , but not in the glomeruli of the kidney . . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
Plasma renin activity ( PRA ) and aldosterone concentration ( PA ) were measured in 20 healthy infants from 1 to 12 months of age during normal ( 3 . 03 mmol / kg / d ) and high ( 5 . 20 mmol / kg / d ) potassium intake . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
In 112 patients with essential hypertension ( HTA ) , free of any therapeutic and receiving the standard ward , a significant inverse relationship was found between age and plasma renin activity ( PRA ) and plasma aldosterone ( PA ) , measured in the supine and upright position . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
Plasma prolactin in normal and hypertensive subjects : relationships with age , posture , blood pressure , catecholamines , and renin . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
We measured plasma renin activity in three groups of female psychiatric inpatients over the age of 50 : a TD group with high plasma DBH activity , a TD group with low plasma DBH activity , and a non TD group . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
Following overnight fast , mean plasma glucose was identical ( 10 patients and normal subjects approximately matched per age and sex ) ; plasma insulin , potassium and renin levels were lower and plasma aldosterone higher in the patients . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
The results indicate that the renin angiotensin system can not be stimulated by furosemide under 106 days of gestation ; the response after 110 days increases with gestational age . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
Plasma renin , aldosterone , and dopamine beta hydroxylase activity in hypertensive patients over 70 years of age ( author ' s transl ) ] . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
Normal integrated concentration of aldosterone and plasma renin activity : effect of age . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
Renin activity in the blood plasma of healthy persons and in hypertension patients depending on age ] . ^^^ The early activation of the renin angiotensin system in the late stages of hypertensive disease should determine specified pathogenetic treatment of this disease in old age . . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
In comparison with group 1 , group 2 was characterized by : ( 1 ) similar values for age , blood pressure , inulin clearance and extracellular fluid volume and ( 2 ) significantly but lower values ( p less than 0 . 001 ) for plasma renin activity with maintenance of the relationship between extracellular fluid volume and renin . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
No differences in renal cortical renin content were found between 2 , 4 , and 8 week olds , but plasma renin concentration was highest at 2 weeks and declined with age . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
After allowance for the decrease of plasma renin activity ( PRA ) with age , direct relationships were observed between PRA ( log values ) and the level of pressure and systolic variability ; plasma angiotensin 2 values did not correlate . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
Corticosteroid biosynthesis from 14C progesterone by the adrenal glands in vitro , 14C aldosterone metabolism by the liver , plasma aldosterone content , and also angiotensin 1 concentration and blood plasma renin activity were studied in Okamoto rats with spontaneous hypertension and in Wistar rats with normal blood pressure , 4 5 weeks of age . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
Plasma renin activity , aldosterone and dopamine beta hydroxylase activity as a function of age in normal children . ^^^ In 149 children between 6 days and 15 years of age , plasma renin activity ( PRA ) and aldosterone ( PA ) were measured by radioimmunoassay and plasma dopamine beta hydroxylase activity ( DBH ) by the method of Nagatsu . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
The effects of propranolol ( 100 mg / kg ) , atenolol ( 200 mg / kg ) and acebutolol ( 1000 mg / kg ) administered daily by gavage to spontaneously hypertensive rats ( SHRs ) from their 6th to 20th weeks of age were investigated on genetic hypertension development ( GHD ) and at regular intervals on heart rate ( HR ) , cardiac output ( CO ) , stroke volume ( SV ) , peripheral resistence ( PR ) , plasma renin concentration ( PRC ) and heart weight / body weight ratio ( HW / BW ) . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
Plasma and kidney renin activity ( PRA , KRA ) were determined in the spontaneously hypertensive ( SHR ) rats , the stroke resistant and prone substrains ( SHRSR , SHRSP ) from 5 to 30 weeks of age . ^^^ However , the activated renin angiotensin system in SHRSP rats in the course of malignant hypertension at 20 weeks of age and later , could participate in raising blood pressure above the levels of the SHR and SHRSR . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
Supine ( basal ) plasma renin activity ( PRA ) and mean arterial pressure ( MAP ) were determined in 564 essential hypertensives grouped by age and sex . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
Influence of age and sodium intake on plasma renin activity of normal subjects . ^^^ Supine and upright plasma renin activity ( PRA ) were measured 1 104 normal subjects ( age range 13 74 years , 71 males and 33 females ) on a constant diet of normal potassium ( 60 80 mEq / day ) and of varying but constant , sodium content ( range 10 260 mEq / day ) . ^^^ These data can explain the contrasting reports on the age influence on renin secretion . ^^^ Therefore , the decline of PRA with age may be explained by the decrease either of renin storage or of sympathetic nervous system activity on renin release . . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
The release of both active and acid activatable ( inactive ) , renin was determined in piglets ranging in age from 3 to 53 days . ^^^ Both isoproterenol and furosemide stimulated release of renin in all age animals while propranolol supressed renin release . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
Plasma renin activity ( PRA ) was determined in conscious piglets between 1 and 50 days of age before and after treatment with saralasin and indomethacin . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
Renin activity and total body potassium fell significantly with age in both groups . 4 . ^^^ The relationship between renin and total body potassium was no longer present when the effects of age were allowed for in a partial correlation . . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
In conclusion , an A 5 fistula provokes two different hemodynamic behaviours which are related to age , pressure values , myocardial performance , presence of a left ventricular hypertrophy , PVR variations , and renin and nor adrenalin blood levels . . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
Effect of age on active and inactive plasma renin levels in normal subjects and in patients with essential hypertension ( author ' s transl ) ] . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
Similarly , no significant difference was found in plasma renin activity , plasma aldosterone level and urinary aldosterone excretion between the neonates whose birth weight was small or appropriate for gestational age . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
Both in male ( n = 353 ) and in female patients ( n = 211 ) with essential hypertension supine ( basal ) plasma renin activity showed an age dependent significant decrease whereas plasma aldosterone remained almost unchanged in women or was even slightly increased with age in men . ^^^ On the other hand , middle aged men ( 35 50 years ) showed a positive relationship between renin and blood pressure whereas in females of the same age group no correlation between these two parameters was found . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
The similarity of duration of hypertension in both groups and the lack of correlation between age and plasma renin activity suggest that low renin hypertension is a separate entity rather than just a later phase of the same disease . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
The results showed that the high levels of renin and angiotensin 2 present in infancy remained above adult levels throughout the first decade of life but that there was a decline with age . ^^^ Boys less than 8 years old had lower plasma renin activity and angiotensin 2 levels than girls of a similar age ; this may be due to a relative substrate deficiency . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
Basal plasma renin activity and plasma aldosterone concentrations were low and did not change significantly with age . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
Renin and big renin ( cryorenin ) were measured in the plasma of 78 babies at birth , and studied in six newborn lambs 2 3 weeks of age in response to angiotensin 2 ( 0 . 25 microgram / kg per min ) infusion . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
Exchangeable body sodium , blood volume , plasma renin activity , norepinephrine or dopamine levels , and norepinephrine or epinephrine excretion rates were similar between 24 patients with borderline hypertension ( mean age 34 + / 4 ( SEM ) years and 22 normal subjects matched for age ; the patients had a slight increase in supine plasma epinephrine . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
Though absolutely normal , noradrenaline in high renin essential hypertension was significantly higher than in low renin essential hypertension ; it correlated neither with age nor blood pressure . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
Plasma noradrenaline , active and inactive plasma renin , cardiac index and total peripheral vascular resistance were studied in 41 subjects , initially aged 10 19 years , who were followed up for at least 2 years after a blood pressure reading of 140 and / or 90 mmHg or more ( initial hypertensives ) and in 41 normotensive control subjects selected from the same population and matched for age , sex and body mass index . 2 . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
Effect of age on active and inactive plasma renin in normal subjects and in patients with essential hypertension . ^^^ The effect of age on the levels of active and trypsin activatable inactive plasma renin was examined in 41 normal subjects and 54 patients with essential hypertension , during recumbency and after stimulation with furosemide and ambulation . ^^^ Active renin levels in supine subjects and patients decreased with age . ^^^ Inactive renin levels did not change with age in normal subjects , whereas in hypertensive patients they decreased with age . ^^^ Following stimulation with furosemide and ambulation , the levels of active renin increased but the responsiveness to stimulus decreased with age in both groups . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
A study was performed in 7 healthy full term newborn infants with mean birth weight of 3130 g ( range , 2650 2850 g ) and a mean gestational age of 38 . 8 weeks ( range , 37 41 weeks ) to investigate the postnatal changes of plasma renin activity ( PRA ) , plasma aldosterone concentration ( PA ) and urinary aldosterone excretion ( UAE ) in relation to electrolyte balance . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
Plasma renin activity ( PRA ) , aldosterone ( PA ) and dopamine beta hydroxylase activity ( DBH ) were measured in 49 subjects over 70 years of age , selected for normal or high blood pressure level . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
Renin binding protein ( RBP ) in hog kidney was characterized and identified as a renin inhibitor . ^^^ The equilibrium was shifted to the complex , suggesting that RBP is present in an excess of renin in the kidney . ^^^ RBP complex is unlikely to occur in the normal kidney because renin and RBP are localized in the granule and cytosol fractions , respectively . ^^^ RBP may provide security against accidental rupture of renin granules under abnormal circumstances . . ^^^ A 56 , 000 dalton renin binding protein in hog kidney is an endogenous renin inhibitor . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
A high performance liquid chromatograph equipped with the newly developed gel , TSK G3000SW , was used to study the interaction between renin and renin binding protein ( RBP ) . ^^^ However , this new high speed gel chromatography provided a clear separation of renin and renin RBP complex within 40 min . ^^^ It also demonstrated that the renin RBP complex was formed at 37 degrees C in the absence of sulfhydryl reagent . ^^^ Demonstration of the formation of renin and renin binding protein complex using high performance liquid chromatography . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
The effect of age on active and cryoactivatable inactive plasma renin in normal subjects and patients with essential hypertension . ^^^ The effect of age on active and cryoactivatable inactive plasma renin levels was examined in 58 normal subjects and 58 patients with essential hypertension during recumbency and after stimulation with furosemide and ambulation . ^^^ Active renin levels declined with age in both supine subjects and patients . ^^^ Inactive renin levels did not change with age in normal subjects , while in hypertensive patients they decreased with age . ^^^ Following stimulation with furosemide and ambulation , the levels of active renin increased but its responsiveness to the stimulus decreased with age in both groups . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
Five men and 8 women , 60 69 yr of age , and 4 men and 5 women , 17 37 yr of age , volunteered for this exploration of possible age related changes in circadian rhythm ( CR ) characteristics of radioimmunoassayable plasma renin ( PRA ) and aldosterone ( PA ) . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
Age related differences in the stoichiometry of the renin angiotensinogen reaction in rat plasma . ^^^ In conclusion , although the catalytic properties of renin do not change with age , subtle differences in the stoichiometry of the reaction may have profound implications in determining compensatory mechanisms involved in renin dependent regulation of homeostasis in developing animals . . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
Sodium , potassium and age : possible determinants of plasma renin activity and aldosterone during childhood ( age 4 16 ) . ^^^ The plasma renin activity ( PRA ) and plasma aldosterone ( PA ) decreased with age : r = 0 . 30 , P less than 0 . 05 for plasma renin activity and r = 0 . 33 , P less than 0 . 05 for plasma aldosterone . ^^^ Using the multivariance analysis , plotting the plasma renin activity against the two combined parameters ( 24 h urinary sodium excretion and age ) , no improvement was obtained ( r = 0 . 38 , P greater than 0 . 05 ) . ^^^ This finding suggests that during childhood , sodium rather than age has a major modulatory role on plasma renin activity . ^^^ With advancing age the plasma aldosterone showed a significant positive correlation coefficient with plasma renin activity ( r = 0 . 29 , P less than 0 . 05 ) . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
Age dependence of human plasma renin substrate . ^^^ Plasma renin substrate concentration was higher at the age of 3 days ( females : 2028 + / 551 , males : 1951 + / 565 micrograms AI / l , mean + / SD ) than in age group 0 15 years ( females : 1513 + / 555 , males : 1263 + / 392 micrograms AI / l ) . ^^^ Plasma renin substrate concentration at the age over 15 years ( females : 1780 + / 464 , males 1752 + / 321 micrograms AI / l ) was higher than in children 0 15 years . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
Systemic and renal haemodynamics , intravascular volume , circulating catecholamines and plasma renin activity were measured in 18 patients with established essential hypertension who were older than 60 years of age . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
Plasma renin activity ( PRA ) was measured in 10 of them , who developed `` pregnancy induced hypertension ' ' ( `` PIH ' ' ) and in 10 normal pregnant women , matched with the hypertensive patients for age , parity and body weight . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
Plasma aldosterone ( PA ) , plasma renin activity ( PRA ) , extracellular fluid volume ( EFV ) and hepatic blood flow were measured in forty four patients with sustained essential hypertension and compared with forty two normotensive controls of same age and sex . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
Plasma noradrenaline concentration in essential hypertension with particular references to age , plasma renin activity and spontaneous fall of blood pressure ( author ' s transl ) ] . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
Plasma renin ( PRA ) and aldosterone activities were measured in 29 obese children and in 48 controls of the same age . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
Plasma atrial natriuretic peptide ( ANP ) , plasma and 24 h urine catecholamines , plasma renin activity ( PRA ) , and serum aldosterone were studied in offspring of hypertensive and normotensive families [ n = 82 ; age 37 + / 7 years ( mean + / SD ) ] . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
The cardiovascular pressor responsiveness to infused norepinephrine ( NE ) or angiotensin 2 ( AII ) as related to endogenous plasma NE or renin levels was assessed in 20 patients with mild parenchymal kidney disease ( plasma creatinine 2 . 20 + / 0 . 58 mg / dl , + / SEM ) and in 20 normal subjects approximately matched for sex and age . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
The age , degree of renal impairment , plasma renin activity , and number and dosage of antihypertensive medicines did not account for these differences in NE . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
An investigation into the renin angiotensin aldosterone system ( RAAS ) in patients of advanced age with ischaemic heart disease ( IHD ) and different degrees of atherosclerotic cardiosclerosis by means of radioimmunoassay , which was used to determine the renin activity and the aldosterone concentration in the plasma , showed that there is in IHD an activation of the above regulatory system even under the conditions of relative rest . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
The interrelationships among age , cardiovascular pressor reactivity to intravenously infused norepinephrine ( NE ) or angiotensin 2 , and endogenous plasma NE or renin ( PRA ) levels were evaluated 1 31 normal subjects and 37 patients with essential hypertension . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
Thus , too often in the past , research into antihypertensive drugs has ignored the importance of underlying plasma drug concentrations and has sought to attribute the variability in antihypertensive response to factors such as age and plasma renin activity . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
The mean values for age , weight , height , basal neutrophil and lymphocyte counts , basal values of cortisol and renin of patients , and sex distribution of group 1 patients ( open , n = 20 ) matched with those for group 2 ( laparoscopic , n = 20 ) , with the exception of age ( p < 0 . 05 ) . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
The SH ( + ) group did not differ significantly in terms of age , heart rate , blood count , plasma biochemistry , plasma renin activity , plasma aldosterone , routine urinalysis , or urinary electrolytes from patients who did not show hypertension [ SH ( ) group ] . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
Effects of age and length of service on the state of the renin angiotensin aldosterone system and prostaglandin synthesis in coal miners ] . ^^^ In this connection activity of renin angiotensin aldosterone system ( RAAS ) in the miners before and after the work appeared to depend on the age and the length of service , to reach the maximum at the age of 31 40 and at 11 15 years of the service . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
The transgenic TGR ( mRen 2 ) 27 rat , in which the Ren 2 mouse renin gene is transfected into the genome of the Sprague Dawley rat , develops severe hypertension at a young age that responds to inhibitors of angiotensin converting enzyme and to antagonists of the type 1 angiotensin 2 ( Ang 2 ) receptor . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
Plasma renin activity was determined in hundred normal subjects of either sex ( M = 65 , F = 35 , age range 2 70 yr ) using Angiotensin 1 test kits . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
However , the plasma renin activity of Beige rats increases with age , whereas that of DA rats decreases . ^^^ These results suggested that giant JG granule formation slightly increases renin release with age , but does not affect blood pressure . . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
Low renin patients ( n = 9 , age 42 + / 3 years ) were defined as those individuals in balance on a low NaCl intake ( 10 mmol NaCl / day for 1 week ) who had a plasma renin activity < 0 . 30 ng angiotensin I / l / s , in both the supine and the upright positions . ^^^ The remaining hypertensives ( n = 18 , age 41 + / 4 years ) were classified into the normal renin group . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
The renal renin mRNA level in sham operated SHR decreased significantly with increasing age , whereas in the Wistar rats the renal renin mRNA level did not change at any age and was not affected by renal denervation . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
METHODS : Systolic tail blood pressure , mean arterial blood pressure , pulse rate , heart mass , body mass and relative heart mass were determined for each rat in the age range 17 19 weeks , and DNA polymorphisms were examined for the guanylyl cyclase A ( GCA ) , angiotensin converting enzyme ( ACE ) and renin ( REN ) genes . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
A male patient with hyperplasia of the juxtaglomerular apparatus , hypokalemia , an associated increase in plasma renin activity and hyperaldosteronism without hypertension was diagnosed as having Bartter ' s syndrome at the age of three . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
The purpose of this investigation was to assess changes in plasma renin activity ( PRA ) and plasma aldosterone in response to prolonged orthostatic stimulation in 19 young men with MVPS when compared to age and sex matched 20 control subjects . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
The levels of estradiol and plasma renin activity correlated in the 45 patients before ( r = 0 . 48 , P = . 001 ) and after ( r = 0 . 46 , P = . 002 ) controlling for age . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
Plasma renin activity ( PRA ) was lower in elderly normotensive subjects and essential hypertensives ( EHT ) , and a significant negative correlation was found between PRA and age in both groups . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
Structure and function of renin binding protein . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
RESULTS : The concentration of total renin in serum was higher in PCOS women than in healthy women independently of BMI , age , or serum insulin . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
When hypertensive patients were divided into those without ( n = 39 ) and with insulin resistance ( n = 16 ) , as defined by an elevated value of the ratio of the area under the curve of the response of insulin and glucose , it appeared that both heart rate , end systolic wall stress to end systolic volume index ratio and afterload corrected fractional shortening were higher in patients with insulin resistance , whereas age , arterial pressure , left ventricular mass index , urinary electrolytes , and plasma renin activity were similar in the two groups . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
The positive response of peripheral renin plasma levels to a single dose of captopril was used as a criterion for selecting 36 patients between 4 and 15 years of age with renovascular hypertension . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
We studied the effects of head down tilt to 10 degrees for 30 minutes on plasma atrial natriuretic peptide and the renin aldosterone system in 8 preeclamptic pregnant women , 8 healthy pregnant women , and 11 nonpregnant women of fertile age . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
RESULTS : The RVH and PH groups were similar with respect to age , sex , body mass index , diabetes , smoking habits , serum triglycerides , cholesterol , and blood pressure values , and differed only in plasma renin activity ( 6 . 0 + / 1 . 7 ng AngI / ml / h in RVH vs . 1 . 4 + / 0 . 3 in PH , mean + / SEM , p = 0 . 008 ) . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
Predictors of favourable blood pressure outcome following revascularization are aetiological ( fibrous dysplasia rather than atheroma ) , historical ( young age , short duration of hypertension ) , physiological ( renal ischaemia confirmed by scintigraphy , lateralizing renal vein renin ratio ) and anatomical ( truncal rather than ostial or branch stenoses ) . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
MAIN OUTCOME MEASURES : To assess the within patient correlations among the blood pressure responses to each drug and explore the possible role of simple characteristics , such as the initial blood pressure , plasma renin concentration and age , in identifying the responders to a particular drug . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
Renin binding protein ] . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
Polymorphisms at the atrial natriuretic factor , antithrombin 3 , renin , angiotensinogen , neuropeptide Y Y 1 receptor , insulin , alpha 2 adrenoceptor , beta 1 adrenoceptor , growth hormone , low density lipoprotein receptor , insulin receptor and renal kallikrein gene loci were found to display similar allele frequencies in each age group of hypertensives , as well as in normotensive controls . 4 . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
Effects of age and sex on sodium chloride sensitivity : association with plasma renin activity . ^^^ The present study was undertaken in 87 Japanese inpatients with essential hypertension to investigate the interrelation among effects of age , sex and the renin angiotensin system on NaCl sensitivity . ^^^ In conclusion , NaCl sensitivity of blood pressure is independently associated with age and the inadequate suppression of the renin angiotensin system . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
Although the activity of the renin angiotensin system is known to decrease with age , the antihypertensive efficacy of angiotensin converting enzyme ( ACE ) inhibitors has been demonstrated in the elderly . ^^^ These results suggest that the activity of the renin angiotensin system in plasma declines with age , and that the extrarenal renin angiotensin system may play a role in hypertension in the elderly . . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
Peripheral plasma renin activity and plasma aldosterone activity increased at the age of 6 months , and ultimately reached the peak at 9 days after discontinuation of furosemide at the age of 7 months . ^^^ Peripheral plasma renin activity and plasma aldosterone activity were normalized at the age of 11 months . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
The relationship between renin responsiveness to furosemide and the antihypertensive effect of captopril in patients with normal renin essential hypertension were studied in 23 patients including nine men ( mean age , 41 years ) and 14 women ( mean age , 40 years ) . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
Nine variables were correlated with survival in the univariate analysis , including resistive index , age , hepatomegaly , blood urea nitrogen , serum creatinine , plasma sodium concentration , glomerular filtration rate , plasma renin activity and plasma concentration of antidiuretic hormone . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
Left ventricular structure and function were assessed with two dimensional targeted M mode echocardiography in 692 men with mild to moderate hypertension ( average blood pressure 153 / 100 mm Hg ) , and the data were compared in relation to obesity ( determined from body mass index ) , age , race , blood pressure , physical activity , plasma renin activity , urinary sodium excretion , hematocrit , heart rate and serum lipids . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
At the age of 42 , he showed hypertension ( 162 / 100mmHg ) , hypokalemia , metabolic alkalosis , low plasma renin activity ( PRA ) and normal plasma aldosterone concentration ( PAC ) in a supine posture . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
The factors examined included age , sex , systolic blood pressure , diastolic blood pressure , plasma renin activity , plasma aldosterone concentration , and sodium and potassium intake as determined by 24 hour excretion . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
Male and female progeny were tested at a prepubescent age ( postnatal day 28 ) by measuring 1 ) the stimulation of adrenocorticotropic hormone , corticosterone and renin by a maximally effective dose ( 0 . 5 mg / kg s . c . ) of the 5 HT1A agonist 8 hydroxy 2 ( di n propylamino ) tetralin ( 8 OH DPAT ) ; and 2 ) [ 3H ] 8 OH DPAT labeled 5 HT1A receptors and [ 3H ] paroxetine labeled 5 HT uptake sites in hypothalamus , cortex and midbrain . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
To evaluate the relationship between kallikrein and salt sensitivity in essential hypertension , active kallikrein excretion , plasma renin activity , atrial natriuretic peptide and aldosterone levels were evaluated in 37 male hypertensives ( mean age 43 . 3 + / 4 . 7 years ) after two weeks on a normal NaCl diet ( 120 mmol NaCl per day ) . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
Clinical and specific examination of 525 patients with special emphasis on ultrasonic , radionuclide and angiographic procedures , a captopril pharmaco radiological test , radioimmunoassay of renin in the renal vein and vena cava inferior provided the diagnosis of vasorenal hypertension ( VRH ) in 65 of them ( 30 males , 35 females at the age of 18 60 ) . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
The plasma renin activity declined with age in NT as well as in EH . ( ABSTRACT TRUNCATED AT 250 WORDS ) . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
In view of this , plasma catecholamines , fasting serum insulin ( IRI ) , urinary sodium excretion ( NaU ) , plasma renin activity ( PRA ) , and plasma aldosterone ( PA ) levels were assessed in young ( age less than 40 years ) normotensive ( n = 27 ) and hypertensive ( n = 14 ) subjects with central obesity and in lean normotensives ( n = 20 ) . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
To test the effects of aging , renin angiotensin system , and pressure on the arterial wall , 20 normotensive male WAG / Rij rats were killed at 6 , 12 , 24 , and 30 mo of age and compared with similar groups treated with an angiotensin ( ANG ) converting enzyme inhibitor ( ACEI ) , perindopril . ^^^ Plasma renin activity decreased with age and increased with ACEI . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
Cardiovascular responses to cold pressor test and associated changes in blood concentrations of renin , aldosterone , and catecholamines were measured in 11 type 1 diabetic patients with microalbuminuria ; 11 type 1 diabetic patients with normoalbuminuria matched for age , duration of diabetes , metabolic control ; and in nine normal control subjects . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
At the age of 4 months significantly lower renal renin activity was observed in spontaneously hypertensive rats than in both normotensive rat strains , Wistar Kyoto and Brown Norway . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
Attempts to rationalise the treatment of hypertension on the basis of pathophysiological and clinical characteristics of patients , such as renin profile and age , have had minimal success in the past . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
It was hypothesized that the OZR would possess low plasma renin values and an increased vascular responsiveness to angiotensin 2 , and therefore , the renin angiotensin system ( PRA , active renin , inactive renin , renal renin content , and plasma angiotensinogen ) and vascular reactivity in OZR at 10 and 24 wk of age were investigated . ^^^ PRA and renin concentration , inactive plasma renin , and renal renin content were all significantly ( P < 0 . 05 ) reduced in OZR when compared with age matched lean controls . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
The diagnostic utility of post captopril renal vein renin ( RVR ) measurements was quantitated in 43 patients ( mean age 62 , range 41 to 77 years ) undergoing aortography to rule out renovascular hypertension ( RVHT ) , and then compared with that of pre captopril RVR measurements . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
Compared with whites plasma renin is low in blacks independently of age , the level of BP and dietary sodium consumption . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
Antihypertensive efficacy of the calcium channel blocker , nilvadipine , was investigated in 21 patients with essential hypertension in relation to the intracellular sodium concentration ( [ Na ] 1 ) in erythrocytes and clinical variables , such as age , body weight , pretreatment blood pressure and plasma renin activity . ^^^ The hypotensive effect of nilvadipine was positively correlated with age ( r = 0 . 67 , p < 0 . 01 ) and inversely correlated with plasma renin activity ( r = 0 . 62 , p < 0 . 01 ) , but was not correlated with erythrocyte [ Na ] 1 or any other indices . ^^^ In conclusion , the antihypertensive efficacy of nilvadipine was predictable by age and renin status , but not by erythrocyte [ Na ] 1 . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
The relationship between pressure dependent renin release and mean arterial pressure ( MAP ) level was assessed in normotensive intact ( n = 10 ) , sympathectomized ( guanethidine at 1 13 wk of age ; n = 8 ) , and renal denervated ( 1 wk before the study ; n = 6 ) rats under normal salt diet . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
There were no differences in age , duration of haemodialysis , blood pressure and the levels of plasma renin activity , noradrenaline , and parathyroid hormone between groups . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
The Na K Cl cotransport activity in red blood cells from essential hypertensive men with low ( n = 8 , mean age 42 + / 4 years ) or normal renin activity ( n = 4 , mean age 43 + / 3 years ) , and in normotensive men with normal renin activity ( n = 7 , mean age 38 + / 4 years ) has been evaluated by means of a recently developed 23Na nuclear magnetic resonance ( NMR ) method . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
Previous research on the ontogeny of sodium appetite in the rat has shown that sodium deficit first engenders sodium intake at 12 days of age , whereas direct stimulation of the brain renin angiotensin system by intracranial injection of renin increases intake of NaCl solution as early as 3 days postnatally . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
It was observed that the microalbuminuric group ( 24 . 5 % of the total population ) was characterized by a higher systemic arterial pressure , a lower level of high density lipoprotein cholesterol , and similar mean values of age , duration of hypertension , glomerular filtration rate , renal plasma flow , filtration fraction , and plasma renin activity when compared with normoalbuminuric subjects . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
To analyze the status of the renin angiotensin system in hypertensive transplant recipients on cyclosporine , we prospectively explored 21 cardiac ( CTR : 52 + / 8 . 2 yr ) and 12 liver ( LTR : 45 + / 10 yr ) transplant recipients on a normal salt diet with 19 normotensive controls in the same age range . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
A decline in the function of the renin angiotensin aldosterone system may induce adaptive changes in response to angiotensin 2 ( ANG 2 ) with age . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
Age related changes in the renin angiotensin aldosterone system and the sympathetic nervous system in patients with essential hypertension ] . ^^^ The aim of this study was to evaluate age , plasmatic renin activity ( PRA ) , plasma aldosterone levels and the total quantity of urinary catecholamines ( TOT . ^^^ These data confirm the changes in the biological , hemodynamic and endocrine profiles observed in elderly hypertensive patients in comparison to young hypertensive patients , and suggests that age may be an important predictive factor of the activity of both the renin angiotensin and sympathetic nervous system which appear to be closely connected and gradually attenuated by age . . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
Despite suppressed kidney and plasma renin , these animals develop fulminant hypertension between 5 and 15 weeks of age . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
Age related changes in the renin aldosterone system . ^^^ Age related changes in the renin aldosterone system in normal humans are well documented . ^^^ There is a close temporal and directional relationship between the age related decrease in plasma renin activity and the age related decrease in plasma aldosterone . ^^^ The primary clinical importance of age related changes in the renin aldosterone system relates to its impact on the proper classification of an individual ' s renin aldosterone profile when attempting to diagnose a clinical condition ( e . g . low , normal or high renin hypertension ) . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
There were no between groups differences relative to age , plasma renin activity , plasma aldosterone , plasma antidiuretic hormone , plasma osmolality , urine sodium or potassium excretion , or creatinine clearance . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
RESULTS The three groups had similar age , severity of heart failure , diuretic dose before treatment , plasma renin activity , and serum electrolyte state . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
The size of renin mRNA did not change with increasing age . ^^^ However , the levels of renin mRNA in kidney RNA decreased 70 % after 12 months of age . . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
In order to evaluate the mid term effects of amlodipine , a 1 , 4 dihydropyridine calcium antagonist , as well as its effects on the renin angiotensin aldosterone system ( RAAS ) , on water and electrolyte balance , on urinary excretion of albumin ( UAE ) and on lipid metabolism , thirteen hypertensive patients ( 2 M , 11 F , mean age 54 years ) were studied in the course of 24 weeks of therapy with amlodipine at 5 10 mg / day . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
The following parameters were studied in a group of patients suffering from essential arterial hypertension complicated by chronic renal insufficiency ( CRI ) , mean age = 64 . 31 + / 1 . 84 , with creatinine clearance ( CrC ) ranging between 30 and 60 ml / min : blood pressure ( systolic and diastolic arterial pressure ) , heart rate , plasmatic renin activity ( PRA ) , plasma levels of aldosterone ( ALDO ) both in clino and orthostatism , as well as some metabolic parameters . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
In caucasian salt replete essential hypertension neither age nor plasma renin activity were major factors . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
We measured blood pressure and plasma renin activity on 100 progeny , 54 males and 46 females , greater than 44 months of age with an abbreviated tether protocol and software program for data collection . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
A multivariate analysis of graft survival using patient race , sex , age , transplant number , current and maximum plasma renin activity , donor race , cold ischemia time and HLA mismatch , the need for dialysis , and the presence of rejection as independent variables . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
However , although the incidence of heart failure rises rapidly with age , relatively little is known about activation of the renin angiotensin and sympathetic nervous system in patients with heart failure over the age of 75 years . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
Angiotensin peptides and plasma levels of renin , angiotensinogen , ACE , and aldosterone were measured at 10 and 20 weeks of age . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
Plasma renin concentration was not elevated , whereas urinary excretion of aldosterone was increased at any age in the low sodium group compared with that in the control group . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
There was a significant age effect on renin mRNA levels ( F = 10 . 0 , P < 0 . 001 ) ; values increase significantly between 0 . 64 and 0 . 95 g ( P < 0 . 005 ) , remain elevated in the newborns ( P < 0 . 05 ) , and subsequently decline in adulthood ( P < 0 . 005 ) . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
We conclude that salt sensitivity is increased with age in essential hypertensives , and renin angiotensin system might be involved in it . . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
Two hundred forty four consecutive patients ( mean age 61 years ) , including 123 who had technically valid renal vein renin ( RVR ) analysis and 121 without RVR data , underwent technically successful percutaneous renal artery angioplasty ( PTRA ) . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
In 52 female F 2 rats ( 25 to 27 weeks of age ) derived from SHR and Wistar Kyoto rats , we determined blood pressure , renin mRNA concentration in the adrenal gland , plasma renin activity , plasma aldosterone concentration , and genotype of the renin gene . ^^^ Paradoxically , the SHR allele of the renin gene or renin gene locus confers a lower rate of aldosterone synthesis at 25 to 27 weeks of age , the mechanism of which remains to be determined . . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
Stepwise multiple linear regression analysis showed that changes of plasma norepinephrine , insulin sensitivity index , plasma renin activity , and age were significant predictive factors for the change of mean blood pressure after weight loss . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
METHODS : A retrospective analysis was performed regarding age and sex of the patients , duration of hypertension , family history of hypertension , preoperative blood pressure , plasma aldosterone concentration ( PAC ) , plasma renin activity ( PRA ) and efficacy of spironolactone on blood pressure between both groups . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
Homology search for the cloned gene revealed that the GlcNAc 2 epimerase was identical with renin binding protein ( RnBP ) in porcine kidney ( Inoue , H . , Fukui , K . , Takahashi , S . , and Miyake , Y . ( 1990 ) J . ^^^ That GlcNAc 2 epimerase is a RnBP was confirmed by its ability to bind porcine kidney renin and mask its protease activity . ^^^ Molecular cloning and identification of N acyl D glucosamine 2 epimerase from porcine kidney as a renin binding protein . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
The three groups did not differ in age , education , body mass index ( BMI ) , estimated aerobic fitness , resting HR , cardiac preejection period ( PEP ) and PEP : LVET ( left ventricular ejection time ) ratio , 24 h Na or K excretion , or fasting lipids , insulin or plasma renin activity . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
The activity of the renin angiotensin system as well as the ability of the kidney to retain sodium following salt restriction are reduced with age . ^^^ The relationship between these age related changes in renal function and the renin gene expression was presently investigated . ^^^ The intrarenal content of renin mRNA did not differ between 10 and 30 month old animals , suggesting that the transcriptional rate of the renin gene is unchanged with age . ^^^ These data suggest that the age related decrease in renal concentration of renin is linked to a modification in the rate of translation of renin mRNA , or to an alteration in the protein maturation . ^^^ The difference in adaptation to the early phase of salt restriction with age should not be linked to changes in renin gene transcription , but more likely to a change in the tissue response to the local renin angiotensin system . . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
Bound prorenin was displaced by rat and human renin or prorenin but not by the prosequence of rat prorenin , angiotensin 1 or 2 , rat or human angiotensinogen , the renin inhibitor SQ 30697 , atrial natriuretic factor , amylase , insulin , bovine serum albumin , hemoglobin , heparin , lysozyme , ovalbumin , cytochrome C , pepsin , pepsinogen , ribonuclease A , mannose 6 phosphate , alpha methyl mannoside , gonadotropin releasing hormone , or an antibody to hog renin binding protein . these results demonstrate specific binding of prorenin to a site in rat tissues , herein named ProBP , that also binds renin . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
Captopril renin test ( CRT ) and captopril angioscintigraphic test ( CAT ) were simultaneously performed in 130 patients with arterial hypertension ( 72 women , 58 men , average age 48 years ) and suspension for renovascular hypertension ( RVH ) in initial renal angioscintigraphy . 16 positive CAT results and 26 positive CRT results according to Muller qualification as well as 31 positive results according to Frederickson qualification were obtained . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
These transgenic rats develop fulminant hypertension at an early age despite low levels of renin in plasma and kidney . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
In 24 patients with essential hypertension , ranging in age from 30 to 68 years , renin status , renal hemodynamics , and sensitivity of BP to steady state changes in salt intake were assessed . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
Normalization of plasma aldosterone , electrolytes , and renin concentrations was achieved at the age of 9 months . . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
To test the hypothesis that renal sympathetic nerves influence the renal and renin responses to furosemide in conscious newborn animals , experiments were carried out in chronically instrumented lambs with either bilateral renal denervation ( denervated , n = 7 , age = 13 + / 3 ( SD ) days ) or intact renal sympathetic nerves ( intact , n = 6 , age = 13 + / 4 ( SD ) days ) , at least 4 days after surgery . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
Included in the analysis were : blood pressure , age , sex , body mass index , endogeneous creatinine clearance , smoking and plasma renin activity . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
This study was designed to examine the changes in kidney morphometry during gestation in fetuses that were either appropriate or small for gestational age and the relationship between umbilical vein plasma active renin and kidney morphometry . 2 . ^^^ The mean umbilical vein active plasma renin concentration at delivery was significantly higher ( P < 0 . 05 ) in the small for gestation age group ( 274 . 4 + / 32 . 9 mu units / ml plasma ) than in the appropriate for gestational age group ( 164 . 9 + / 28 . 3 mu units / ml plasma ) . ^^^ Umbilical vein plasma renin levels were higher in small for gestational age fetuses . ^^^ The findings of slow fetal renal growth rate and associated high renin concentrations seen in small for gestational age fetuses could be implicated in an irreversible reno vascular pathology leading to adult hypertension . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
Plasma renin activity and plasma prorenin are not suppressed in hypertensives surviving to old age . ^^^ An age related decline in plasma renin activity ( PRA ) has been described in normotensive and hypertensive subjects . ^^^ We therefore investigated whether that pattern of renin and prorenin suppression was apparent in white hypertensives and normotensives surviving to an older age . ^^^ However , since an inverse relationship between PRA and age has been reported , it remains to be determined whether the renin / prorenin parameters were suppressed at any time or if normal renin and normal prorenin patients preferentially survive to an old age . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
SUBJECTS AND METHODS : In 383 hospitalized Caucasian essential hypertensives ( 198 men , 185 women ) of mean age 44 + / 0 . 5 years and mean clinic blood pressure 170 . 3 + / 0 . 95 / 103 . 4 + / 0 . 47 mmHg , metabolic parameters , serum creatinine level ( Cs ) , creatinine clearance rate ( Ccs ) , 24 AER and plasma renin activity ( PRA ) were measured . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
Age related changes in plasma aldosterone and corticosterone concentrations as well as in plasma renin activity in response to 10 days of sodium deprivation were studied in old as compared to adult male Long Evans rats . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
METHODS AND RESULTS : Estrogen status and components of the renin angiotensin system were examined in a population based sample of postmenopausal women and age matched men . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
Developmental studies demonstrate age dependent elevation of renin activity in TGR ( mRen 2 ) 27 rats . ^^^ Systolic blood pressure and left ventricular mass index ( LVMI ) were measured in transgenic heterozygote and normotensive Sprague Dawley control rats at 25 , 35 , 45 , 55 , 65 , and 75 days of age together with determinations of plasma active renin and prorenin , and renal and adrenal tissue renin , which were assayed at pH 6 . 5 , 7 . 4 , and 8 . 5 . ^^^ Plasma active renin of the transgenic rats , measured at physiological pH , was significantly higher from 55 days of age , increasing in parallel with blood pressure and remaining significantly higher than controls at all age groups tested . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
Urine retinol binding protein ( RBP ) , N acetyl beta D glucosaminidase ( NAG ) , albumin , bacteriuria , systolic blood pressure , glomerular filtration rate ( GFR ) , peripheral plasma renin activity ( PRA ) and the degree of renal scarring were measured in each subject ; 20 had bilateral and 35 unilateral renal scarring ; 5 were hypertensive and none were in renal failure . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
PATIENTS AND METHODS : From a population of 114 patients with documented primary aldosteronism , we selected 23 never treated patients ( 12 males , 11 females ; 11 tumoral , 12 non tumoral ) and compared them to patients with never treated essential hypertension with low renin ( supine plasma renin activity < 1 ng / ml per h , n = 23 ) or normal renin ( supine plasma renin activity between 1 and 4 ng / ml per h , n = 23 ) , matched for age , body mass index , mean arterial pressure , renal function and known duration of hypertension . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
In normally reared control animals , renal renin and liver angiotensinogen mRNA decreased between 6 and 30 postnatal days of age . ^^^ In contrast , in the central nervous system , angiotensinogen mRNA increased between 6 and 30 days of age , and renin mRNA remained stable . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
Plasma ( PV ) and red cell volumes ( RCV ) , 24 h ambulatory blood pressure ( BP ) , 24 h natriuresis and morning plasma aldosterone , renin activity and atrial natriuretic peptide in 11 men with a mean age of 47 y ( range 37 55 ) , apnoea index ( AI ) of 55 ( 22 106 ) , body mass index of 36 ( 30 43 ) and seated BP of > or = 140 / 90 mmHg without any medication were measured . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
To study the relations between neuropeptide Y ( NPY ) and age , gender , blood pressure ( BP ) and risk factors for cardiovascular disease and the renin angiotensin system , we performed a population based study through random selection of 220 subjects ( 49 % men ) . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
A specific renin binding protein has been identified in cardiac tissue . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
Sixteen postmenopausal women with essential hypertension , with a mean age of 59 years and diastolic blood pressures of 95 to 115 mm Hg , were enrolled in a 12 week , single blind study to determine the effects of losartan on blood pressure , renal and extrarenal PG production , plasma renin activity ( PRA ) , plasma aldosterone , and routine biochemical parameters . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
These results , coupled with findings that the mRen 2 transgene product converts rat angiotensinogen more effectively than endogenous rat renin , that the TGR may have high circulating mouse renin levels which increase with age , and the fact that high circulating prorenin concentrations are present in these TGR , shed light on the kidney ' s role in the blood pressure elevating mechanisms of TGR . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
To determine whether pretreatment plasma renin activity ( PRA ) , without accompanying 24 h urine sodium , can predict myocardial infarction ( MI ) , the PRA levels of 2 , 902 hypertensive patients [ white ( 38 % ) , male ( 65 % ) , median age 55 years ] , with mean entry blood pressure ( BP ) of 150 / 97 mm Hg were examined . ^^^ In a Cox survival analysis only renin , age , sex , smoking , LVH , and cholesterol were significantly ( P < . 02 ) related to MI occurrence . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
METHODS : We measured the plasma concentrations of digoxin like immunoreactive substances ( by a fluorescence polarisation immunoassay ) and natriuretic peptides , aldosterone , renin , and antidiuretic hormone ( by radioimmunoassay ) in ten patients with aneurysmal subarachnoid haemorrhage , ten patients undergoing elective craniotomy for cerebral tumours , and 40 healthy controls of similar age and sex distribution . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
In comparison with normal subjects of the same age ( group N , n = 13 ) , those from group E did not differ in body mass index , plasma lipid profile , fasting glucose , insulin and catecholamine ( CA ) concentrations , but had increased erythrocyte sodium content , slightly elevated plasma renin activity and cortisol level . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
DESIGN : A population based sample of 615 middle age subjects was studied by standardised echocardiography ; anthropometric measurements ; and biochemical quantification of renin , pro renin , angiotensinogen , angiotensin converting enzyme ( ACE ) , and aldosterone . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
The aim of the present study was to analyse age dependent changes in renal haemodynamics and renal renin secretion which could be of pathophysiological importance in the course of the disease . ^^^ We investigated glomerular filtration rate ( GFR ) , renal blood flow ( RBF ) , renal vascular resistance ( RVR ) , plasma renin activity ( PRA ) , the autoregulatory behaviour of RBF and the pressure dependent plasma renin activity in conscious PKD rats compared with age matched controls . ^^^ The basal plasma renin activity was significantly ( P < 0 . 05 ) lower in 3 month old PKD than in old PKD and age matched controls . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
Effects of LV mass , adiposity , race , age , physical activity , height , weight , sodium excretion , plasma renin activity and heart rate were examined . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
At the age of 12 months , haptoglobin phenotypes and plasma active renin concentration were determined as well as random urine evaluation of aldosterone , cAMP , dopamine and digoxin like immunoreactive substances ( DLIS ) . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
A population based study was performed in order to study the interrelationships of the circulating components of the renin angiotensin system during basal conditions and their relations to blood pressure ( BP ) , age and gender . ^^^ Plasma renin activity ( PRA ) correlated negatively with age ( r = 0 . 30 , P < 0 . 0001 ) , but immunoreactive active renin ( IRR ) and angiotensin 2 did not . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
Renal , but not extra renal , renin mRNA levels declined with age . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
Since an elevated urinary albumin excretion ( UAE ) has been indicated as a negative prognostic marker for cardiovascular diseases in essential hypertensives , we evaluated UAE in 50 male patients with mild to moderate essential hypertension ( mean age 46 . 3 + / 4 . 4 years ) , characterized as low renin ( LR ) ( n = 14 ) , modulating ( M ) ( n = 20 ) , and NM patients ( n = 16 ) according to their renin profile and ability to modulate the aldosterone response to a graded infusion of angiotensin 2 . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
Plasma renin activity remained high until about the age of 8 years , after which it decreased to almost within the normal range . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
The study groups included 13 patients with low renin essential hypertension ( average age 43 . 5 + / 16 . 2 years ) , 16 patients with normal renin essential hypertension ( 46 . 5 + / 13 . 4 years ) , 11 patients with high renin essential hypertension ( 40 . 7 + / 13 . 8 years ) and 12 healthy subjects ( 43 . 1 + / 11 . 4 years ) . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
Human renin binding protein : complete genomic sequence and association of an intronic T / C polymorphism with the prorenin level in males . ^^^ The role of renin binding protein ( RnBP ) in human ( patho ) physiology , despite its biochemical characterization , is as yet unclear . ^^^ RnBP has been shown to bind and inactivate renin , a key player of the blood pressure regulating renin angiotensin system . ^^^ Herein , a molecular genetic approach was employed to investigate if RnBP might affect renin , prorenin and / or blood pressure levels . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
Age , weight , and baseline blood pressure , heart rate , urinary sodium excretion , plasma renin , angiotensin 2 , and aldosterone concentrations did not differ between genotypes . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
Univariate regression analysis revealed a significant correlation between LV mass and averaged cyclosporine levels , but no correlation between LV mass and blood pressure , cold ischemic time , acute rejection , age , body mass , blood pressure , plasma catecholamine levels , or plasma renin activity . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
In the present study , the components of this pathway were investigated in left ventricles of hearts from hypertensive transgenic rats overexpressing the mouse renin gene [ TG ( mREN 2 ) 27 ] in comparison to age and weight matched Sprague Dawley control rats . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
We have studied a patient with severe hypertension , low renin and aldosterone , and a chronic hypokalemic alkalosis at age 4 . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
The hypertension was defined as severe , resulting in stroke before age 50 years , featuring normal renin , aldosterone , and catecholamine responses , and did not appear to be salt sensitive . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
The renin angiotensin system changes with age , but it is unclear how renal responses to angiotensin 2 ( Ang 2 ) evolve as an animal matures . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
Multivariate analysis adjusting for systolic blood pressure , body mass index , and age revealed that renin and ANP were independently associated with LV mass index ( p < 0 . 05 each ) . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
We measured cardiac volumes , diastolic and systolic functions , systemic ( Doppler echocardiography ) and renal hemodynamics , intrarenal sodium handling ( lithium clearance method ) , plasma and urinary cGMP , plasma renin concentration , and plasma aldosterone level in six healthy volunteers ( mean age , 33+ / 3 years ) receiving CNP ( 2 and 4 pmol / kg per minute for 1 hour each ) in a single blind , placebo controlled , random order , crossover study . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
Structure of the gene encoding rat renin binding protein . ^^^ The gene encoding renin binding protein was isolated from a Sprague Dawley rat genomic DNA library and the exon intron boundaries and transcription initiation sites were identified . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
Post natal development of plasma and urine osmolality , as well as plasma renin activity , aldosterone and cortisol levels were studied in calves between 1 and 9 months of age . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
The response of blood pressure and plasma renin activity ( PRA ) 1 h after 50 mg captopril administration were evaluated in 82 inpatients with untreated essential hypertension ( 42 men , 40 women ; mean age + / SD : 52 + / 13 years ; range : 27 to 79 years ) in relation to ACE genotypes . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
Because nonhemodynamic factors seem to play a fundamental role in the development of LVH , the present study was undertaken to investigate the relationship between the predialysis renin level and the echocardiographically determined cardiac structure in stable hemodialysis patients , matched for other parameters known to participate in the development of LVH , such as age ; gender ; body mass index ; interdialytic weight gain ; heart rate ; systolic , diastolic , and mean arterial BP ; hematologic and biochemical profile ; vascular access ; adequacy of dialysis ; nutritional status ; and period of follow up . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
At the adult age , LH rats differed from LN rats by elevated BP , left ventricle weight , and vascular resistances , especially in the kidneys , associated with lower kidney renin and prorenin contents . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
METHODS AND RESULTS : Using data from a large population based sample of 1488 siblings having a mean age of 14 . 8 years and belonging to the youngest generation of 583 randomly ascertained three generation pedigrees from Rochester , Minn , we carried out variance components based linkage analyses to evaluate the contribution of variation in four renin angiotensin system gene regions ( angiotensinogen , renin , angiotensin 1 converting enzyme , and angiotensin 2 receptor type 1 ) to interindividual variation in systolic , diastolic , and mean arterial pressure . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
MATERIALS AND METHODS : Activity of plasma renin ( APR ) , angiotensin converting enzyme ( ACE ) , plasma levels of angiotensin 2 ( AII ) and vasopressin ( VP ) , serum concentration of aldosteron ( AS ) were measured by radioimmunoassay and enzyme immunoassay in 21 PPH patients with circulatory failure ( age 34 . 7 + / 2 . 1 years ) , 11 patients with NYHA functional class 2 3 , 10 with class 4 , and 10 control subjects ( age 29 . 8 + / 1 . 5 years ) . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
There were no differences in age , blood pressure , retinopathy grade , presence of proteinuria , or resting plasma renin activity ( PRA ) among the hypertensive patients with the 2 , ID , and DD genotypes . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
Oral administration of cisapride caused a two fold increase in the plasma aldosterone levels ( 182 . 6 + / 28 . 0 % in high renin state and 203 . 4 + / 38 . 6 % in low renin state ; P = 0 . 659 between the means of two states ) without affecting the plasma renin levels , Scatterplot of percentile aldosterone increment against age distribution demonstrated that the R square were very low ( 0 . 039 for high renin and 0 . 009 for low renin state ) . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
The two groups of patients were similar in sex , age , systolic / diastolic blood pressure , supine / upright plasma renin activity , supine / upright aldosterone , tumor size . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
However , prenatal glucocorticoid exposure did not alter vascular sensitivity to noradrenaline , angiotensin 2 and adrenocorticotropic hormone in these sheep at any of the ages studied , nor did it affect basal or adrenocorticotropic hormone induced concentrations of cortisol or basal plasma renin concentrations in the lambs at any age . 4 . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
Following 6 weeks of double blind treatment with placebo or 0 . 25 to 16 mg / day trandolapril , an analysis of drug effect on trough blood pressure ( BP ) stratified by age , gender , weight , pre treatment plasma renin activity , and trandolaprilat concentration was performed . ^^^ There were no observable differences based on age , gender or measurements of the renin angiotensin aldosterone axis . ^^^ In conclusion , neither age , gender or plasma renin activity influenced anti hypertensive response to angiotensin converting enzyme inhibition in African Americans . . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
These calcium antagonists are effective in lowering blood pressure and reducing anginal episodes in African Americans and whites , regardless of age or renin level . . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
METHODS : Total renin concentrations ( TRC ) were measured with a time resolved immunofluorometric assay in 38 patients with IDDM ( age 34 ( SD 7 ) years , duration of disease 22 ( 7 ) years , serum creatinine 95 ( 15 ) mumol / l , urinary albumin excretion rate ( UAER ) 207 ( 829 ) micrograms / min , HbA1c 8 . 5 % ( 1 . 2 % ) ) , and in 13 matched normal subjects . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
METHODS : This systematic review of the literature investigated genetic variation in the renin system according to race , sex and age . ^^^ In five studies ( n=989 ) on the renin gene , the Hind 3 and Taq 1 polymorphisms varied with the groups ' average age , whereas the Bg 1 , Bg 2 and Hind 3 but not Taq 1 sites differed according to race . ^^^ CONCLUSION : With adjustments applied for the subjects ' enrollment group and the methods of genotyping , genetic polymorphism in the renin system varies according to race and age , but not sex . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
DESIGN AND METHODS : Plasma levels of renin , prorenin , angiotensinogen , ACE and aldosterone , as well as angiotensinogen and ACE genotypes were determined in 228 men and 168 women ( age 52 65 years ) , who had participated in a population survey in southern Germany . ^^^ After adjustment for sex , age and blood pressure , the T 235 allele of the angiotensinogen gene was also related to lower plasma prorenin ( P < 0 . 03 ) and renin ( P < 0 . 01 ) levels , but not to plasma ACE and aldosterone . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
The best combinations of predictor variables contained mean arterial pressure , plasma renin activity , creatinine concentration and age ( r 2 = 14 . 4 % , P = 0 . 37 ) . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
METHODS : Hypertensive transgenic ( mREN 2 ) 27 rat ( TGR ) that exhibit increased tissue renin expression were administered streptozotocin ( STZ , diabetic ) or citrate buffer ( non diabetic ) at six weeks of age , and sacrificed 4 and 12 weeks later . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
The relationship between age and plasma neurohormones ( norepineprine , epinephrine , dopamine , renin , aldosterone , atrial natriuretic peptide , N terminal atrial natriuretic peptide , and endothelin ) , and age and prognosis was examined . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
Thirty four patients ( 65 . 3+ / 3 . 3 years of age , mean+ / SEM ) with hyperkalemia ( serum potassium > 5 . 0 mEq / L ) had measurement of their renin aldosterone system . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
Significant associations between the 825T allele and diastolic blood pressure , plasma renin , and prorenin levels ( inverse ) , and the aldosterone to renin ratio persisted after adjustment for age , gender , body mass index , and systolic blood pressure . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
A BsII PCR / RFLP in the renin binding protein ( RnBP ) gene on canine chromosome 10 . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
These animals develop fulminant hypertension and cardiac hypertrophy at an early age despite low levels of renin in the plasma . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
There was no correlation between MA and age , sex , body mass index , systolic or diastolic blood pressure , plasma renin activity , serum ACE levels or left ventricular index . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
No association was observed with blood pressure , body mass index , age , plasma renin , angiotensinogen , angiotensin converting enzyme , cholesterol , triglycerides , or HDL or LDL cholesterol . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
Human renin binding protein is the enzyme N acetyl D glucosamine 2 epimerase . ^^^ The existence of human renin binding protein ( RnBP ) in the kidney has been shown by the isolation and characterization of a complex of porcine renin human RnBP [ S . ^^^ The purified recombinant human RnBP ( rhRnBP ) exists as a dimer and inhibits porcine renin activity through formation of a complex of porcine renin with rhRnBP , the so called high molecular weight renin . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
Adducin genotype was significantly ( R2=0 . 11 , F=6 . 5 ; P < 0 . 01 ) and directly related to fraction excretion of lithium ; gender , age , urinary Na+ , urinary uric acid , mean blood pressure , and plasma renin activity were not related . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
In the study usefulness of active renin ( AR ) measurement instead of plasma renin activity ( PRA ) in the diagnosis of reno vascular hypertension ( RVH ) was evaluated . 42 patients with arterial hypertension ( 17F , 25M ; mean age 45 + 12 years ) and suspicion on RVH on the ground of the abnormal result of the preliminary renal angioscintigraphy were qualified to the study . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
The prognostic value for a good outcome was evaluated using age , creatinine clearance , plasma renin activity , plasma aldosterone , and Pugh score . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
SUBJECTS AND METHODS : Exchangeable sodium , plasma and blood volumes , and catecholamine , renin , and aldosterone levels were assessed in 10 patients with Type 2 diabetes mellitus who had orthostatic hypotension and control groups of 40 diabetic patients without orthostatic hypotension and 40 normal subjects of similar age and sex . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
The two groups were comparable in terms of age , gender , plasma renin activity , human leukocyte antigen mismatches , and cause of renal failure . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
Twenty four hour BP ( SpaceLabs SL 90207 ) , 24 h urine excretion of catecholamines , plasma renin activity and plasma aldosterone concentration were therefore determined in 10 nephrotic patients with normal serum creatinine levels ( group A , serum creatinine 1 . 0+ / 0 . 2 mg / dl ) , in 10 nephrotic patients with increased serum creatinine levels ( group B , serum creatinine 2 . 4+ / 0 . 9 mg / dl ) and in 20 controls matched in respect of age and BP . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
MEASUREMENTS : Gene expression of angiotensinogen , renin , renin binding protein , angiotensin converting enzyme ( ACE ) and angiotensin 2 ( ang 2 ) receptor type 1 in human preadipocytes ; ACE protein and ang 2 production of human adipose tissue stromal cells differentiated or not in primary culture . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
Tsukuba hypertensive mice ( THM ) carrying both the human renin and angiotensinogen genes and C57BL / 6J control mice 2 to 3 months of age were fed with either a western or normal diet for 14 weeks . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
Renin aldosterone system and atrial natriuretic peptide during anesthesia in orthopedic patients over 80 years of age . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
MATERIALS AND METHODS : In order to explore the expression of renin angiotensin system genes in human adipose tissue and adipocytes , total RNA was isolated from whole adipose tissue ( subcutaneous and omental ) or cultured adipocytes ( mammary ) and subjected to reverse transcriptase polymerase chain reaction with primers specific for human angiotensinogen , renin , renin binding protein , angiotensin converting enzyme , chymase and type 1 and type 2 angiotensin receptors . ^^^ Furthermore , we found expression of the chymase and renin binding protein genes in these samples . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
Cardiac hypertrophy was shown to be related to age and gender with the copy number of mouse renin transgenes having an additive effect . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
Plasma PAI 1 antigen , tPA antigen , plasma renin activity , and aldosterone were measured in 25 normotensive subjects ( 19 white , 6 black ; 14 men , 11 women ; mean age 38 . 5+ / 1 . 8 years ; mean body mass index 25 . 3+ / 0 . 7 kg / m ( 2 ) ) during low salt intake alone ( 10 mmol Na / d ) , low salt intake + quinapril ( 40 mg PO bid ) , and low salt intake + losartan ( 50 mg PO bid ) . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
METHODS : We studied plasma renin , prorenin , and four polymorphic markers of the renin gene in 199 patients with IDDM and DN , and in 192 normoalbuminuric IDDM controls matched for age , sex , and duration of diabetes . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
RESULTS : Age , blood pressure , body mass index , 24 h urinary sodium excretion and plasma renin activity were in the 2 groups with and without hormone replacement therapy . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
Identification of cysteine 380 as the essential residue for the human N acetyl D glucosamine 2 epimerase ( renin binding protein ) . ^^^ Renin binding protein ( RnBP ) is a proteinous renin inhibitor firstly isolated from porcine kidney . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
METHODS : Ninety nonobese , nondiabetic , nonhyperlipidemic patients with mild to moderate essential hypertension ( 67 males , 23 females ; mean age 51 . 4 + / 6 . 2 years ) were divided into low renin ( LR ) , normal renin ( NR ) , and high renin ( HR ) subgroups according to individual PRA while they were on a constant NaCl intake ( 120 mmol NaCl / day ) . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
There was no correlation between gestational age , Na ( + ) K ( + ) ATPase , plasma renin activity and aldosterone values either in the preterm or term babies . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
PATIENTS AND METHODS : In the 12 patients with hyperaldosteronism , retrospective analysis of clinical ( age , sex , blood pressure ) , biochemical ( plasmatic and urinary potassium , plasmatic aldosterone , plasma renin activity , and plasmatic aldosterone / renin activity ratio ) , and morphological ( computed tomography , magnetic resonance , and norcholesterol scintigraphy ) data was performed . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
Similarly , in response to early exposure to cold stress and maternal deprivation , there was an increase in plasma renin activity levels of congenital learned helpless rats with age of presentation to either stressors . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
We measured plasma and platelet magnesium concentrations , plasma epinephrine and norepinephrine , and plasma aldosterone and renin concentrations in normotensive ( NT Ob , n = 19 , BMI 35 . 7 + / 7 . 4 kg / m2 , WHR 0 . 92 + / 0 . 05 ) and hypertensive ( HT Ob , n = 11 , BMI 35 . 2 + / 3 . 6 kg / m2 , WHR 0 . 93 + / 0 . 07 ) obese subjects , and in a group of age and sex matched lean controls ( n = 14 , BMI 23 . 1 + / 1 . 8 kg / m2 , WHR 0 . 79 + / 0 . 05 ) . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
DESIGN : Plasma renin activity ( PRA ) was measured in 38 patients with stable chronic heart failure ( 21 male , 17 female ; mean ( SD ) age 71 ( 6 ) years , range 59 82 years ) on chronic diuretic treatment alone . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
Plasma renin activity was significantly increased by low sodium diet and significantly decreased by high sodium diet , with no significant difference between the responses of the 2 age groups . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
PATIENTS AND METHODS : 62 patients with TS , age 5 . 4 22 . 4 years , had 24 h ABPM ( ambulatory blood pressure monitoring ) , echocardiography , renal imaging and measurement of recumbent plasma renin activity ( PRA ) . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
A strong relationship was found with age ( r= 0 . 54 , P < 10 ( 4 ) ) and plasma renin activity ( r=0 . 32 , P < 10 ( 4 ) ) in women but not in men . ^^^ We conclude that age , gender , and plasma renin are strong determinants of the aldosterone response to Ang 2 , with strong sibling correlations in men and postmenopausal women . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
Normal blood pressure and plasma renin activity in mice lacking the renin binding protein , a cellular renin inhibitor . ^^^ In renal extracts , some renin is present as `` high molecular weight renin , ' ' a heterodimeric complex of renin with the 46 kDa renin binding protein ( RnBP ) , also known as N acyl D glucosamine 2 epimerase . ^^^ Because RnBP specifically inhibits renin activity , the protein was proposed to play an important role in the regulation of the renin angiotensin system ( RAS ) . ^^^ In particular , we analyzed biosynthesis , secretion , and activity of renin and other components of the RAS in mice lacking RnBP . ^^^ Contrary to previous hypotheses , we conclude that RnBP does not play a significant role in the regulation of renin activity in plasma or kidney . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
In this study of 37 healthy human volunteers , distributed among three groups ( group 1 : n = 13 , age range 20 39 years ; group 2 : n = 13 , age range 40 59 years ; group 3 : n = 11 , age range 60 68 years ) , we evaluated the influence of age on some of the vasoactive systems such as plasma renin activity , urinary kallikrein , plasmatic prokallikrein , plasmatic kallikrein , and plasmatic kininogen on RPF and creatinine clearance ( Ccr ) in response to an acute oral protein load ( 1 g / kg body weight ) . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
The expression of renin binding protein and renin in the kidneys of rats with two kidney one clip hypertension . ^^^ OBJECTIVE : To test the hypothesis that renin binding protein ( RnBP ) is involved in modulating the intracellular processing or release of renin , we examined the expression of RnBP in clipped and contralateral kidneys of rats with two kidney one clip hypertension , and in left and right kidneys from sham operated control rats . ^^^ Renin binding protein is expressed mainly in renal tubules and collecting ducts unlike renin , which is expressed in the glomerular afferent arteriole . ^^^ CONCLUSION : Renin binding protein expression is unchanged between clipped and contralateral kidneys . ^^^ Reverse transcription polymerase chain reaction on renal mRNA was performed using primers for renin , RnBP , glyceraldehyde 3 phosphate dehydrogenase ( GAPDH ) and angiotensin converting enzyme ( ACE ) . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
We tested the hypothesis that endothelin ( ET ) ( A / B ) receptor blockade with bosentan ( 100 mg / kg by gavage after age 4 weeks ) ameliorates cardiac and renal damage by decreasing inflammation in rats harboring both human renin and angiotensinogen genes ( dTGR ) . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
Plasma renin activity and plasma angiotensin 2 level was equivalent in the 9 and 12 week old SHRSP and the WKY rats ; both parameters , however , were elevated in 24 week old SHRSP as compared with age matched control . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
Sex and age adjusted IMT did not differ between quartiles of renin sodium profile . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
RESULTS : There were no differences between transplant patients , with and without PTE , with respect to weight , age , sex , blood pressure , serum creatinine , circulating renin , angiotensin 2 , and Epo levels . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
We have developed a new assay method for GlcNAc 2 epimerase activity using a system of N acyl D hexosamine oxidase coupled with peroxidase and employed this method to study the effects of renin on GlcNAc 2 epimerase activity . ^^^ The recombinant human ( rh ) RnBP existed as a dimer and its GlcNAc 2 epimerase activity was strongly inhibited by the purified renin concomitant with the formation of RnBP renin heterodimer , so called high molecular weight ( HMW ) renin . ^^^ These results indicate that renin is an inhibitor of GlcNAc 2 epimerase , and the renin RnBP heterodimer HMW renin is an inactive form of both renin and GlcNAc 2 epimerase activities . . ^^^ Renin inhibits N acetyl D glucosamine 2 epimerase ( renin binding protein ) . ^^^ Renin binding protein ( RnBP ) is a highly specific renin inhibitor first isolated from porcine kidney . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
Renin and heart rate responses to haemorrhage are age dependent in conscious lambs . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
Untreated transgenic rats overexpressing the human renin and angiotensinogen genes ( dTGR ) feature hypertension and severe left ventricular hypertrophy with focal areas of necrosis , and die at age 7 weeks . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
The following initial measurements were significantly ( P < 0 . 002 ) associated with subjects who had died compared with subjects known to be alive : age at study , pulse pressure , systolic , diastolic , and mean arterial pressures , hypertension , salt sensitivity , baseline renin levels , and body mass index ( but not body weight ) . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
Other univariate predictors of greater blood pressure responses included black race , female gender , higher pretreatment blood pressure , older age , lower waist to hip ratio , and measures of lower renin angiotensin aldosterone system activity . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
Renin binding protein ( RnBP ) is an endogenous renin inhibitor originally isolated from porcine kidney . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
In a multiple regression model including age , sex , body mass index , and changes in systolic pressure , plasma renin activity and plasma aldosterone and urine volume , salt excretion resulted as the stronger independent predictor of urinary ADM ( r = 0 . 33 , P = . 01 ) . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
Moreover , a 5 fold increase of renin mRNA was observed in hearts of HTG rats between day 2 and the third month of age . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
Plasma renin activity was suppressed by a high salt intake in all age groups , and baseline values declined with advancing age . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
No changes in mean arterial pressure , or plasma angiotensin 2 , aldosterone , and renin activity levels were noted at either gestational age . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
Age , weight , number of palliative operations , plasma renin activities and pulmonary to systemic flow ratios ( 3 . 5 vs . 3 . 5 ) were not significantly different prior to Captopril or Propranolol therapy . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
Total renin minus renin is the PP level ; PP was correlated with the presence of ROP , stage of ROP , gestational age , birth weight , and postnatal age . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
Renin immunostaining was localized to the afferent arterioles , with a greater percentage of arterioles staining in rats with CHF ( 55 . 3 % + / 2 . 1 % ) than in sham operated ( 43 . 9 % + / 1 . 9 % ) or normal age controls ( 37 . 6 % + / 2 . 2 % ) . ^^^ Rats with CHF more frequently exhibited multiple bands of renin staining within a single arteriole ( 24 . 9 % + / 1 . 8 % ) as compared with sham operated ( 13 . 3 % + / 1 . 9 % ) and normal age controls ( 11 . 3 % + / 1 . 4 % ) . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
Plasma renin activity is significantly lower in black people compared with whites independent of age and blood pressure status . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
RESULTS : At the univariate analysis , New York Heart Association ( NYHA ) class ( p < 0 . 0001 ) , age ( p < 0 . 0001 ) , male gender ( p < 0 . 0001 ) and plasma renin ( p < 0 . 0001 ) significantly related with peak Vo 2 . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
In 130 subjects with IDDM , aged 15 . 2+ / 4 . 8 years and diabetes duration 7 . 3+ / 5 years , and in 48 controls of comparable age , UFC , urinary endothelin ( UET 1 ) , urinary albumin , HbA1c , and plasma renin were determined . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
Doppler indices of renal vascular resistance were closely related to the duration of the disease , age , and plasma renin activity . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
We observed that candesartan increased renin mRNA in all rats at all ages , the amplitude of stimulation being inversely related to age . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
On the other hand , porcine renin inhibited recombinant GlcNAc 2 epimerase activities . ^^^ Renin binding protein ( RnBP ) is an endogenous renin inhibitor originally isolated from porcine kidney as a complex of renin , so called high molecular weight ( HMW ) renin . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
CONCLUSIONS : The data indicate the effects of renal denervation on renin mRNA expression in the kidney are age dependent and that the fetus in late gestation has a mechanism for maintaining renin mRNA levels after denervation , which is absent or nonfunctional in the adult . . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
METHODS : Serum potassium , leptin , aldosterone , insulin levels and plasma renin activity were measured and hyperinsulinaemic euglycaemic clamp was performed in 11 patients with PA and 11 healthy age , gender and body mass index ( BMI ) matched subjects . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
Although differences in race , age and measures of the renin angiotensin aldosterone system ( RAAS ) have been associated with variation in blood pressure response to hydrochlorothiazide , whether these characteristics make additive contributions to predicting response has not been established . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
The purified chimeric enzymes had GlcNAc 2 epimerase activity and inhibited renin activity in a dose dependent manner . ^^^ Identification of a domain conferring nucleotide binding to the N acetyl d glucosamine 2 epimerase ( Renin binding protein ) . ^^^ Renin binding protein ( RnBP ) , a cellular renin inhibitor , has been identified as the enzyme N acetyl D glucosamine ( GlcNAc ) 2 epimerase . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
Although certain demographic features including age , ethnicity , and diabetes mellitus predispose to low renin hypertension , these factors account for only a minority of cases . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
Plasma renin concentrations at this age were lower in the uninephrectomized lambs ( P < 0 . 05 ) . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
We measured BP and plasma levels of neurohumoral factors ( norepinephrine [ NE ] , epinephrine , renin , and arginine vasopressin [ VP ] ) during the 70 degree head up tilt test ( 10 min supine and 15 min tilting ) in 120 older subjects ( mean age 71 years ) who had sustained hypertension as determined by ambulatory BP monitoring . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
METHODS AND RESULTS : Concentrations of atrial natriuretic peptide ( ANP ) , brain natriuretic peptide ( BNP ) , endothelin 1 ( ET 1 ) , renin , aldosterone , norepinephrine , and epinephrine were determined in 53 adults with congenital heart disease , comprising 4 distinct anatomic subgroups ( 29 female ; 33 . 5+ / 1 . 5 years of age ; New York Heart Association class 2 . 0+ / 0 . 1 , mean+ / SEM ) and 15 healthy control subjects ( 8 female ; 32 . 3+ / 1 . 3 years of age ) . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
A regression analysis showed that CVI ( s ) was predicted by the PQ duration , supine plasma renin activity , plasma aldosterone , and age , which collectively accounted for approximately 36 % of CVI ( s ) variance . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
MATERIAL / METHODS : In 31 patients with essential hypertension ( EHP 14 F , 17 M , age 44I14 years , BMI 29 . 3I6 . 4 kg / m2 ) and 8 healthy subjects ( NHS 4 F , 4 M , age 37 ( 17 years , BMI 25 . 3I6 . 6 kg / m2 ) plasma leptin concentration , plasma renin activity ( PRA ) , and 24 hour urinary sodium excretion ( UNa ) were evaluated twice : first on a diet containing 100 120 mmol sodium per day and after 8 hours overnight bed rest , and a second time after 3 days of dietary sodium restriction ( 10 20 mmol daily ) and 3 hours in upright position . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
METHODS : The responses of renal and systemic vascular resistances ( RVR and SVR ) and plasma noradrenaline and renin ( NOR and PRA ) to systemic NO stimulation and inhibition were studied in patients with grade 1 essential HT and age and sex matched NT subjects . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
The following measures were found to be significantly associated with the risk for death : blood pressure ( systolic , diastolic , mean arterial , and pulse pressures ) , hypertension , age , salt sensitivity , baseline renin levels ( inverse ) , and body mass index ( but not body weight ) . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
RESULTS : Proteinuria remained the single most important predictor of long term renal function ; other predictors included baseline GFR , blood pressure , plasma renin activity , lipid profile , age , weight / body mass index , and diabetes duration . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
Age and gender matched wild type ( + / + ) and homozygous null mice ( / ) were administered captopril for 7 days , and plasma and renal renin levels and renal renin mRNA expression were measured . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
Recent clinical trials have demonstrated effective antihypertensive activity in hypertension , independent of age , renin and salt status or ethnic origin , and have also highlighted the potential for vasopeptidase inhibition as a new therapeutic modality for the treatment of CHF . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
The study groups included 10 patients with low renin essential hypertension ( average age 42+15 years ) , nine patients with medium renin essential hypertension ( 46+13 years ) , 11 patients with high renin essential hypertension ( 42+14 years ) and 12 healthy subjects ( 43+11 years ) . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
Diagnosis may be made at any age in most forms of low renin hypertension . . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
No differences in age , fat mass , homeostasis model assessment ( HOMA ) , the summation of insulin ( sigmaIRI ) , plasma renin activity ( PRA ) or 24 h norepinephrine excretion ( 24hU NE ) were observed between the hypertensive ( HT ) group ( n = 31 ) and normotensive ( NT ) group ( n = 71 ) before weight loss , but the basal serum leptin was significantly higher in the HT ( 16 . 8 + / 1 . 1 ng / ml ) than in the NT group ( 15 . 2 + / 0 . 8 ng / ml ) , after adjusting for abdominal total fat . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
Additional factors associated with resolution of hypertension based on univariate analysis included younger age , shorter duration of hypertension , higher preoperative ratio of plasma aldosterone concentration to plasma renin activity , and higher urine aldosterone level ( P < 0 . 05 ) . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
The rise in BP was not dependant on age , the change in plasma renin activity or weight . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
Also , plasma renin activity was significantly lower in the female offspring of hypertensive mothers at 10 weeks of age ( P < 0 . 05 ) , suggesting that development of the renin angiotensin system was altered . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
Female TGR ( mREN 2 ) 27 rats harboring the mouse Ren 2 renin gene were treated with Flutamide ( specific antagonist of the androgen receptor , 30 mg / kg per day ) starting at 4 weeks of age . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
In group B , microalbuminuria correlated with ambulatory BP , and plasma renin activity failed to decrease with chronological age . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
METHODS : In nine hypertensive male patients ( age 46 64 years ) undergoing diagnostic renal artery angiography and renal vein catheterization to determine plasma renin activity ( PRA ) , a 3F Doppler catheter was positioned in the renal veins using a 7F guide catheter with a `` basket ' ' shaped tip . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
In a protocol in which animals were matched for age , at 11 . 5 wk , terminal systolic blood pressure and urine protein excretion were elevated in SHAM and OVX+E2 rats compared with OVX rats ; blood urea nitrogen , renal microvascular and glomerular lesions , and plasma renin concentration were elevated in OVX+E2 relative to SHAM or OVX rats . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
According to a multiple logistic regression analysis , the age and baseline plasma renin activity adjusted relative risk ( odds ratio ) for the lack of a depressor response conferred by the D allele ( assuming an additive effect ) was 2 . 72 [ 95 % confidence interval ( CI ) , 1 . 07 6 . 91 ; p = 0 . 034 ] ; for DD genotypes , as compared with the DI and 2 genotypes ( assuming that the D allele is recessive ) , it was 11 . 7 ( 95 % CI , 2 . 25 60 . 6 ; p = 0 . 003 ) . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
Because it is known that renin angiotensin system ( RAS ) activation and defective glucose control contribute to adverse renal outcomes , we examined renal responses to high glucose and to manipulation of the RAS in adolescents ( mean age 14 + / 2 years ) with uncomplicated type 1 diabetes , segregated into two groups on the basis of the presence or absence of normal N / D BP ratio . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
Assignment of the gene encoding renin binding protein ( Renbp ) to rat chromosome Xq 37 by in situ hybridization and radiation hybrid mapping . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
Arterial hypertension was observed at about 4 months of age and was associated with high levels of plasma renin activity and circulating angiotensin , and also with changes in renal Doppler ultrasonography . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
METHODS : In 227 consecutive patients with hypertension ( mean age + / SD : 53 . 3 years + / 13 . 4 , 126 men ) , we measured : PWV , LAD , LVPWT , mean 24 hours SBP , plasma renin activity , and plasma aldosterone and catecholamine levels . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
At 5 , 10 , and 15 days of age , renal tissue renin activity and Ang 2 concentration were measured by radioimmunoassay . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
To date , we have chosen several target transcription factors such as NFkappaB ( nuclear factor kappaB ) and E2F to prevent the progression of diseases , and negative regulatory element ( NRE ) for the renin gene and angiotensinogen gene activating element ( AGE ) for the angiotensinogen gene to examine the molecular mechanisms of gene expression . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
We studied the nocturnal plasma concentration of ACTH , cortisol , renin and aldosterone , and sleep EEG in 7 medication free patients with depression ( 1 male , 6 females , age : ( mean + / SD ) 53 . 3 + / 14 . 4 yr . ) and 7 age matched controls ( 2 males , 5 females , age : 54 . 7 + / 19 . 5 yr . ) . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
Plasma norepinephrine . epinephrine , renin angiotensin system activity , ANP , BNP , and serum interleukin 6 ( IL 6 ) and tumor necrosis factor ( TNF ) alpha were measured in 84 CHF patients ( age , 59 + / 1 years , LVEF , 36 + / 1 % ) and 34 controls . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
Calcium antagonists are effective in hypertensive patients of all ethnic groups , irrespective of age , dietary salt intake , salt sensitivity status or plasma renin activity profile . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
FMD was negatively and significantly correlated with plasma aldosterone ( r= 0 . 38 , P=0 . 0006 ) , 24 hour urinary aldosterone ( r= 0 . 49 , P < 0 . 0001 ) , and ratio of plasma aldosterone to plasma renin activity ( r= 0 . 43 , P < 0 . 0001 ) but was independent of blood pressure , age , and body mass index . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
Age dependence of the levels of plasma norepinephrine , aldosterone , renin activity and urinary vanillylmandelic acid in normal and essential hypertensives . ^^^ Primary hyperaldosteronism was not detected among the normokalemic essential hypertensives at any age using aldosterone / plasma renin activity ratio as a primary screening method . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
MEASUREMENTS : Analysis of polymorphisms in genes coding for angiotensinogen ( AJT 704T > C ) , angiotensin 2 receptor 1 ( AGTR 1 1166A > C ) , renin ( REN 2646G > A ) , renin binding protein ( RENBP 61T > C ) , alpha adducin ( ADD 1 1378G > T ) , beta 2 adrenergic receptor ( ADRB 2 46A > G , 79C > G ) , and angiotensin 1 converting enzyme ( ACE I / D ) was performed by polymerase chain reaction and restriction fragment length polymorphism analysis . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
We evaluated the effects of a subpressor ADMA dose on NO production , renal hemodynamics , sodium handling and active renin and noradrenalin plasma concentrations in 12 healthy subjects ( age 26 + / 1 year ) using a double blind placebo controlled study design . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
In a multivariate logistic regression containing renin status ( low renin vs normal / high renin ) , aldosterone on a high sodium diet , age , body mass index , gender , race , duration of hypertension , systolic and diastolic blood pressure and salt sensitivity only low renin status on a low sodium diet ( P=0 . 019 ) and serum aldosterone on a high sodium diet ( P=0 . 04 ) were significant predictors of LVH . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
Variables considered included age , gender , race , body mass index ( BMI ) , hypertension status , blood pressure , basal RPF , creatinine clearance , serum insulin , serum glucose , serum high density lipoprotein ( HDL ) , serum triglycerides , and plasma renin activity ( PRA ) . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
As other targets , we focused on negative regulatory element ( NRE ) for the renin gene and angiotensinogen gene activating element ( AGE ) for the angiotensinogen gene to examine the molecular mechanisms of gene expression , AP 1 and ets 1 . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
At 4 weeks of age , the kidneys of male offspring were harvested to measure cortical AT 1 and AT 2 receptor expression , 125I Ang 2 glomerular binding , tissue renin activity , tissue Ang 2 and plasma aldosterone concentrations . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
About one half of double transgenic rats ( dTGR ) overexpressing the human renin and angiotensinogen genes die by age 7 wk of terminal heart failure ( THF ) ; the other ( preterminal ) one half develop cardiac damage but survive . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
When rendered sodium hungry by ivc renin or by sodium depletion , these sucklings prefer urine and NH4Cl to NaCl , dilute urine , or an NaCl and KCl mineral mix equimolar to urine ; however , by 18 days of age , urine and NH4Cl are no longer preferred to NaCl . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
In this study , ACE levels and renin concentrations were measured in the sera of 16 patients with RA ( median age : 45 ( 26 69 ) , male / female : 3 / 13 ) , 13 patients with osteoarthritis ( OA ) ( median age : 55 ( 28 72 ) , male / female : 5 / 8 ) , and 11 healthy adults ( median age : 44 ( 35 70 ) , male / female : 6 / 5 ) . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
Results were compared according to age , gender , the number of HLA matches , plasma renin activity levels , etc . , with 52 patients ( control ( C ) group ) under cyclosporin A , mycophenolate mofetil and steroids treatment . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
There were no significant differences in the age of recipients ( 42 . 3+ / 11 . 3 vs . 39 . 4+ / 14 . 1 ) , as well as in HLA matching ( 2 . 2 / 6 M vs . 2 . 2 / 6 M ) , in the number retransplanted patients ( 10 . 3 % vs . 10 . 4 % ) and in highly sensitized patients ( plasma renin activity > 50 . 0 % ) ( 5 . 1 % vs . 4 . 8 % ) between those groups . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
Amino acid residues conferring the nucleotide binding properties of N acetyl D glucosamine 2 epimerase ( renin binding protein ) . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
In multivariate analysis , serum bilirubin , renin , ET 1 , PGE 2 , decreased urinary sodium excretion and age were identified as predictors of renal dysfunction . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
After an infusion of AGE RSA , renal expression of angiotensinogen , ACE , renin , and angiotensin receptor type 1 were increased significantly ( all P < 0 . 01 ) , and ACE activity was elevated . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
Systolic , diastolic , and mean BP values and plasma renin activity concentration were obtained in 422 young adults who were born with a gestational age ( GA ) < 32 weeks . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
METHODS AND RESULTS : Concentrations of N terminal pro atrial natriuretic peptide , N terminal pro brain natriuretic peptide ( NT proBNP ) , endothelin ( ET ) 1 , renin , aldosterone , adrenalin , and noradrenalin were determined in 50 adults ( mean age , 27 . 8 + / 1 . 7 years [ + / SEM ] ; 26 women ) with tetralogy of Fallot ( TOF ) after surgical repair ( New York Heart Association functional class 1 . 1 + / 0 . 1 ) . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
After adjustment for other predictors of the renal plasma flow response to captopril using a multivariate linear regression model , there was a highly significant relationship between age and plasma renin activity adjusted body mass index and the renal plasma flow response to captopril ; however , a quadratic model provided a substantially better fit ( r=0 . 55 ; P < 0 . 0001 ; P=0 . 03 versus linear correlation ) . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
Age may affect this balance by influencing blood pressure ( BP ) or renin responses . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
Age did not significantly affect plasma arginine vasopressin or aldosterone levels , but renin activity was only 8 % in 31M WR rats relative to 3M WR ( P < 0 . 05 ) . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
Renal interlobar artery parameters with duplex Doppler sonography and correlations with age , plasma renin , and aldosterone levels in healthy children . ^^^ OBJECTIVE : The objectives of this study were to compare and make correlations between age and Doppler parameters of the interlobar arteries , including synchronously obtained plasma renin and aldosterone levels and to obtain new normative data regarding acceleration time in healthy children from neonates to 16 years . ^^^ Age had a negative correlation with the RI , PI , plasma renin levels , and aldosterone levels and correlated positively with acceleration time . ^^^ We showed that the age dependency of the RI was directly related to that of plasma renin and aldosterone levels in healthy children in whom Doppler parameters and blood analysis were evaluated synchronously . . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
In women , there was a significant positive correlation between the left ventricular mass index and age , as well as plasma renin activity and smoking . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
The regression model included presence / absence of sympathetic autonomic neuropathy , age , diabetes duration , presence / absence of hypertension , baseline SBP and neuro hormonal parameters ( plasma adrenaline , noradrenaline , plasma renin activity , and aldosterone ) . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
The beat to beat continuous heart rate , hematocrit ( Hct ) changes during HD , serum levels of nitric oxide , plasma levels of catecholamine , renin , endothelin ( ET 1 ) , cardiac output ( CO ) , and peripheral vascular resistance ( PVR ) were measured before and after HD in patients prone to develop intradialysis hypertension ( n = 30 ) and from age , sex matched control HD subjects ( n = 30 ) . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
In multivariable models , plasma aldosterone was associated positively ( P < 0 . 05 ) with blood pressure in older individuals ( interaction with age , P < 0 . 05 ) and with waist circumference in men ( interaction with sex , P < 0 . 05 ) and negatively with high density lipoprotein cholesterol , in particular in individuals with elevated urinary potassium excretion ( interaction with urinary potassium , P < 0 . 05 ) ; plasma renin activity was significantly associated with triglycerides and fasting blood glucose . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
At the age of 12 weeks p47phox / mice showed increased plasma renin activity as analyzed by radioimmunoassay ( 14 . 5+ / 1 . 8 ng / mL / h vs . 9 . 6+ / 1 . 7 ng / mL / h , P < 0 . 05 , n=10 ) and enhanced angiotensin converting enzyme ( ACE ) activity in the kidney and aorta as measured by Hip His Leu cleavage ( 7 . 6+ / 0 . 8 vs . 4 . 8+ / 0 . 9 nmol / L His Leu / mg protein , P < 0 . 05 , n=5 ) compared to wild type mice . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
In age and sex adjusted models , several biomarkers were related to baseline brachial artery diameter ( PAI 1 , CRP , urine albumin creatinine ratio ) , baseline mean flow ( N ANP , BNP , PAI 1 , CRP , aldosterone ) , FMD ( N ANP , PAI 1 , CRP , renin ) , and reactive hyperemia ( BNP , PAI 1 , CRP , renin , urine albumin creatinine ratio ) . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
They developed a Bartter like syndrome characterized by a mild phenotype : hypokalemia occurred only at the age of 22 years ; it was corrected with small doses of oral potassium in one twin , while the other twin needed no potassium supplements to maintain borderline levels of plasma potassium ; alkalosis was absent ; plasma renin and aldosterone production were not markedly activated . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
The Ren vascular bed showed no consistent response in both age groups . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
The single dose pharmacokinetics of nefazodone ( NEF ) and its metabolites hydroxynefazodone ( HO NEF ) and m chlorophenylpiperazine ( mCPP ) were examined in 12 healthy younger subjects < or = 55 years of age ( YNG ) , 12 elderly subjects > or = 65 years of age ( ELD ) , 12 patients with biopsy proven hepatic cirrhosis ( HEP ) and 12 patients with moderate renal impairment ( REN ) , ClCR 20 60 ml . min 1 . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
Subjects were white , 55 years of age or younger , and living with the patient and their child ( ren ) aged 7 to 16 years old . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
The objectives of the present study were to examine the life circumstances , childhood abuse , and types of homicidal acts of 48 mothers who killed / attempted to kill their child ( ren ) under age 12 between 1970 96 in Finland . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
All participants had a child ( ren ) under 4 years of age and were currently enrolled in a primary care or family HIV clinic . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
Disparities in health care and good health between African Americans and other populations while established in the literature are traditionally based on socioeconomic measures of race , income , age , and education ( Bailey , 2000 ; Lillie Blanton , Brodie , Rowland , Altman and McIntosh , 2000 ; Ren and Amick , 1996 ; Watson , 2001 ; Weinick , Zuvekas , and Cohen , 2000 ) . ^^^
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
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Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
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Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
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Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
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Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
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Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
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Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
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Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
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Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
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Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
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Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
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Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
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Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
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Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
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Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
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Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
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Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
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Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
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Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
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Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
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Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
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Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
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Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
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Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
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Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
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Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P00797 and P51606	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NA
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
Despite comparable body sodium fluid balance in the two age groups , serum renin concentration , plasma renin activity and aldosterone concentrations were lower in the elderly . ^^^ The age related decreases in circulating renin and aldosterone concentrations were slight while subjects were supine and receiving normal sodium intake ; when upright and during sodium depletion , they were more pronounced . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
The degree of the individual hemodynamic changes after propranolol correlated better with the corresponding control values than with age or renin . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
Renin and age as determinants of a predominantly betablocker based antihypertensive drug program . ^^^ The proportion with low renin hypertension increases with age . ^^^ On this basis , it is postulated that the older patients with a low renin exhibit a relatively hypoadrenergic state whereas those with a normal or high renin for a given age and elevated pressure have a relatively increased adrenergic nervous activity . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
A beta blocker based antihypertensive drug program guided by age and renin . ^^^ From analyses of the effectiveness of beta blocker monotherapy in relation to the patient ' s age and to pre treatment renin determinations an antihypertensive drug program is proposed in which beta blockers form the cornerstone . ^^^ The proportion with low renin hypertension increases with age . ^^^ On this basis , it is postulated that the older patients with a low renin exhibit a relatively hypoadrenergic state while those with a normal or high renin for a given age and elevated pressure have a relatively increased adrenergic nervous activity . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
Renin and age , determinants of the beta blocker effect in essential hypertension ] . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
Hypotensive effect following beta adrenergic block in 10 day puppies and alfa adrenergic block in puppies of all age groups is accompanied by the increase in renin activity . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
Patients in this group were older than those with normal renin levels , and there was a significant negative correlation between renin and age among all patients . ^^^ It is concluded that low renin hypertension does not represent a separate diagnostic entity but that plasma renin falls with age in essential hypertension . . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
In urine samples of newborns , angiotensin concentrations were in the same range as those found in the amniotic fluid ; renin activity was very low or undetectable in the urine of male neonates ( 1 7 days of age ) . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
Influence of age on orthostatic changes in plasma renin activity and urinary catecholamines in man . ^^^ The authors studied plasma renin activity ( PRA ) , urinary epinephrine , norepinephrine and dopamine excretion and their mutual relationships in 54 healthy subjects under basal ( recumbent ) conditions and age related orthostatic changes in these parameters . ^^^ The diminished capacity of older subjects for catecholamine mobilization and raised renin secretion during an orthostatis stress may be related to the higher incidence of orthostatic forms of hypotension in old age . . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
Plasma cortisol and renin were estimated in 1 h intervals , plasma aldosterone , angiotensinogen and angiotensinases in 3 h intervals over periods of 24 h in six normal volunteers ( age 20 26 ) under control conditions and subsequently under suppression of ACTH release by dexamethasone . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
With increasing age and blood pressure , plasma catecholamine concentrations rise while the reactivity of heart rate and renin secretion decreases . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
In a survey of 3 California communities by the Stanford Heart Disease Prevention Program , we obtained data on blood pressure , medications , age , height and weight , blood for measurement of plasma renin activity ( PRA ) , plasma renin concentration ( PRC ) , plasma renin reactivity ( RR ) , and plasma renin substate concentration ( PRS ) , and urine for measurement of urinary sodium and creatinine . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
The possibility that bradykinin , a potent vasodilator , might be a physiological antagonist of the renin angiotensin system was investigated . 11 norman subjects , ranging in age from 21 to 33 yr were studied . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
Antihypertensive beta blocking action as related to renin and age : a pharmacologic tool to identify pathogenetic mechanisms in essential hypertension . ^^^ The proportion of patients with low renin hypertension progressively increased with increasing age and blood pressure , there being no difference between the sexes . ^^^ Age may heolp in patient selection but is no substitute for the more reliable renin index , especially in patients over age 40 years , or with high pressure . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
The hypertension is characterized by low plasma renin activity and , with increasing age , normal to high plasma aldosterone . 3 . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
Blood pressure , plasma renin activity , plasma aldosterone , urinary noradrenaline during sleep ( UNA S ) and several estimates of sodium intake were determined in 379 normotensive subjects ( age 13 70 ) to investigate the relationship of these variables to blood pressure . 2 . ^^^ Blood pressure was correlated with age , weight , plasma renin activity UNA S , and estimates of sodium intake . ^^^ Multiple correlation analysis revealed that after removal of the effects of age , blood pressure was related to weight , plasma renin activity , UNA S and estimates of sodium intake . 4 . ^^^ However , multiple regression analysis failed to demonstrate an effect of plasma renin activity , UNA S , or estimates of sodium intake on blood pressure when the effects of age , weight , race and sex were removed . 5 . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
Plasma noradrenaline concentration and plasma renin activity were measured in a control , British , urban population ( n = 115 ) in which blacks were matched for age and sex with whites . 2 . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
Relationship of basal plasma noradrenaline to blood pressure , age , sex , plasma renin activity and plasma volume in essential hypertension . 1 . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
The size and number of renin containing GCT cells increased rapidly in males , attaining adult status by 50 days of age . ^^^ In females , differentiation of GCT cells immunoreactive for renin was slower and less regular than in males , and at 50 days of age the GCT segment had not yet reached adult conditions with respect to the distribution of renin . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
None of the following were related independently with variability : age ; race ; sex ; plasma renin activity ; plasma angiotensin 2 ; plasma noradrenaline ; plasma adrenaline . . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
To characterize the renin angiotensin system in the Aoki Okamoto spontaneously hypertensive rat ( SHR ) more fully , serial measurements of plasma renin activity ( PRA ) , plasma renin concentration ( PRC ) , renin reactivity ( as relative index of circulating modifiers of the renin reaction ) and renin substrate concentration were made in 6 to 64 week old SHR and in age matched Wistar Kyoto normotensive rats ( WKY ) . ^^^ However , elevated renin reactivity did not account for the transition from normal to high PRA observed in mature SHR , nor did renin substrate concentration , which was consistently lower in SHR than in age matched WKY . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
Simultaneous measurement of plasma renin activity ( PRA ) , plasma aldosterone concentration ( PA ) and urinary aldosterone excretion ( UAE ) was made using the RIA method along with determination of Na and K balance in 1 week old neonates with gestational age of 30 41 weeks ( mean 35 . 9 weeks ) and birth weight of 1 , 160 4 , 670 g ( mean 2 , 680 g ) . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
In essential hypertension mean basal ( supine ) and stimulated plasma renin activity ( 2 h upright posture + 40 mg furosemide intraveneously ) decreased progressively with age . ^^^ In female patients changes in mean stimulated plasma aldosterone with increasing age paralleled those of plasma renin activity , whereas in males this relationship was less obvious : only a slight age related decline in stimulated aldosterone levels was observed and significantly lower plasma aldosterone concentrations in male than in female hypertensives of the younger age groups ( less than 40 years ) were found . ^^^ The results indicate that in essential hypertension with increasing age dissociation between plasma aldosterone and plasma renin activity occurred . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
The renin activity of plasma the age dependence and prognostic and therapeutic significance ( author ' s transl ) ] . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
The fluctuation of plasma renin activity in response to an excess of sodium chloride or to thiazide treatment was reduced progressively with age . ^^^ The age related decrease of plasma renin activity is discussed on the light of the age related impairment in the ability of the kidney to excrete sodium and water . . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
Strict criteria were employed for renin profiling the hypertensive patients , including age matching , exclusion of diabetics , and the use of medications known to interfere with the renin response or with DOC measurements . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
Plasma aldosterone concentrations and plasma renin activity according to age and their relationships with electrolytes of plasma and erythrocyte and oral sodium intake in normal neonates and children ( author ' s transl ) ] . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
A sample of 278 children , stratified by diastolic ( fourth phase ) blood pressure and specific for age , race , and sex , was reexamined 1 2 yr after initial observation for the following : ( 1 ) a physical examination and urinalysis to exclude secondary hypertension ; ( 2 ) 24 hr urine sodium , potassium , plasma renin activity , and serum dopamine beta hydroxylase ; ( 3 ) 1 hr oral glucose tolerance test ; and ( 4 ) heart rate and blood pressure at rest and under standarized physical stress . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
The poor responsiveness of the RAS in Group 2 is attributed to an inadequate adrenergic activity and to an increased mean arterial pressure in that group , but the higher age of patients and longer duration of hypertensive disease , both characteristic of the group of medium severity , may also effect the renin angiotensin system . . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
The highest mean age and the longest duration of the disease history are typical for patients with low plasma renin activity . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
Plasma renin activity ( PRA ) and plasma aldosterone concentration ( PA ) were measured in 20 healthy infants 2 12 months of age , after taking a commercial modified cow ' s milk formula with 8 . 2 mmol / l sodium for at least five days , and after at least five days on a home made , undiluted acidified cow ' s milk formula with 12 . 6 mmol / l sodium . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
Total kidney renin content increases with age . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
Relationships between blood pressure , age , plasma renin activity and electrolyte excretion in normotensive subjects . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
Patient age , blood pressure , and plasma renin activity did not differ between the two races . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
The study presented here clearly shows that age and sex have an important influence on plasma renin activity . ^^^ Women had lower values than age matched men , and studies in normal volunteers showed that plasma renin activity decreases with age . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
Influence of age on the renal renin response to a high salt intake in the rat . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
With this treatment , plasma renin activity and aldosterone were normal or almost normal beyond the age of 6 . 5 months , but urinary aldosterone 18 glucuronide remained slightly increased . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
Using RIA for determining the plasmatic renin activity in orthostatism according to the method of Fyhrquist we obtained in the control group of adult subjects nonsignificant variations in relation with sex and age , and in the group with Cushing ' s syndrome associated with arterial hypertension nonsignificantly increased values as against the controls . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
Age , blood pressure , renin and urinary electrolytes in primary hypertension and in the normotensive state . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
Groups of patients with low and high renin hypertension differed significatly from each other not only br PRA after stimulation , but also by PRA at rest , PV and age . . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
An inverse relationship between the aortic renin content of the spontaneously hypertensive rat and the progressive increase of systolic blood pressure was observed with age . ^^^ In contrast to this strain of rat , aortic renin of the normotensive WKY strain did not decline with age . 3 . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
Plasma renin activity was lower in 89 previously untreated `` hypertensive ' ' subjects than in an equal number of age and sex matched `` controls ' ' from the same community . ^^^ Plasma renin activity fell with both increasing age and increasing arterial pressure . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
Whilst there were significant differences in age between the high , normal and low renin groups , there were no significant differences in basal blood pressure , response to diuretics or beta blockers . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
Changes in plasma renin levels of normotensive and spontaneously hypertensive rats with increasing age [ proceedings ] . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
A significant decrease in renin activity was revealed in males and females over 40 years of age with labile and stable forms of hypertensive disease . . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
The molecular weight of plasma renin of female WK at the age of 90 , 120 , and 200 days ranged from 41 , 000 to 43 , 000 showing little variation . 3 . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
Age versus urinary sodium for judging renin , aldosterone , and catecholamine levels : studies in normal subjects and patients with essential hypertension . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
Plasma renin activity was related to race and inversely to age in hypertensive patients ( P less than 0 . 05 ) but not in normal subjects . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
Plasma renin activity , arterial and venous angiotensin 2 ( A 2 ) concentrations , and plasma aldosterone concentration were measured in 16 normal subjects ( mean age = 34 years ) after 8 hours of recumbency , following 2 hours of ambulation , and again 30 minutes after administration of furosemide intravenously . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
Plasma renin activity ( PRA ) , supine , erect and post frusemide ( 1 mg / kg 4 ) was studied in 51 patients with previously untreated essential hypertension and their age and sex matched normotensive controls . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
Plasma renin concentration correlated inversely with both total peripheral and renal vascular resistance as well as with age . ^^^ Multiple regression analysis indicated that part of the relationship between renin and haemodynamic variables did not depend on age . ^^^ Furthermore , plasma renin concentration did not decrease with age in a group of 40 normotensive control subjects of similar age to the hypertensive patients . 4 . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
There were no differences with age , sex and severity of hypertension except for the level of peripheral plasma renin activity between the two groups . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
This is indicated by the observation that prevalence of low renin hypertension increases with age and that it is more frequent in advanced stages of hypertension . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
Interrelations between age and plasma renin , aldosterone and cortisol , urinary catecholamines , and the body sodium / volume state in normal man . ^^^ Interrelations between age and plasma renin , aldosterone and cortisol levels , urinary catecholamiens , plasma and blood volumes , exchangeable body sodium and blood pressure wwere studied in 28 young ( 19 to 29 years ) , 16 middle aged ( 32 to 58 years ) and 15 elderly ( 60 to 74 years ) healthy subjects . ^^^ There were no significant age related differences in the body sodium / volume state , basal plasma cortisol levels or urinary adrenaline excretion rate , and plasma renin or aldosterone levels did not correlate with these parameters or with blood pressure . ^^^ It is concluded that the influence of age on plasma renin or aldosterone levels , plasma cortisol responsiveness to upright posture , and urinary noradrenaline excretion should be taken into consideration , whenever these factors have to be interpreted in patients with arterial hypertension or other clinical disorders . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
Plasma renin activity ( PRA ) , aldosterone ( Aldo ) , 17alpha hydroxyprogesterone ( 17 OHP ) and testosterone ( T ) , together with urine sodium , pregnanetriol , 17 oxosteroids and the 11 oxygenation index ( 11 OH ) were estimated in 23 patients ( age 5 . 7 18 yrs . ) with congenital adrenal hyperplasia ( CAH ) due to 21 hydroxylase deficiency during glucocorticoid treatment . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
The relationship of plasma and urinary aldosterone with sodium balance , plasma renin activity and age in normal subjects . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
Age and the renin aldosterone system . ^^^ Age effect on plasma renin activity ( PRA ) and PRA classification was studied in young and older normotensive volunteers . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
Plasma renin activity under both test conditions declined with increasing age , especially those over 40 . ^^^ Response of renin activity to sodium restriction and standing was 73 per cent of that of the younger age group . ^^^ Renin substrate did not decline with increasing age . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
The mean level of plasma renin activity fell with increasing age of hypertensive patients . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
In babies ranging in age from 1 to 25 weeks and in children between 1 and 14 years , plasma renin activity and urinary aldosterone activity were determined in relation to urinary sodium excretion . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
Plasma renin activity in normal children : its relationship to age and rates of excretion of sodium and potassium . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
Postural changes in plasma renin activity were studied in three groups of age and duration matched male diabetics ( potent , impotent and with postural hypotension ) and in non diabetic control subjects . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
Compared with a group of normal pregnant women , matched for age , parity , posture , and length of gestation , women with hypertension and proteinuria in the last trimester had significantly lower plasma concentrations of renin , renin substrate and angiotensin 2 . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
A statistically significant reverse relationship was found between the age of the hypertensive patients and their plasma renin activity ; this parameter tends to decrease along with the increasing duration of the disease . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
The results were compared to data of 5 patients under propranolol matched according to age , arterial blood pressure , and renin concentration . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
Plasma renin activity and plasma aldosterone in essential hypertension : effect of age and diastolic blood pressure ] . ^^^ In patients with essential hypertension a gradual decrease in basal and stimulated renin secretion was found with increasing age . ^^^ Young patients ( less than 35 years ) with high renin hypertension had lower diastolic blood pressure than patients with low renin hypertension in the same age group . ^^^ Contrary to these findings , a markedly higher diastolic blood pressure was observed in patients over 35 years of age with high renin hypertension than in the group of patients with low renin hypertension . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
Once daily dosage beta blockade : antihypertensive efficacy of slow release oxprenolol as related to renin and age . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
Reduced plasma renin activity in essential hypertension : effects of blood pressure , age and sodium . 1 . ^^^ Supine plasma renin activity and its responsiveness to erect posture and frusemide were reduced in fifty one patients with essential hypertension , compared with fifty one age and sex matched control subjects . 2 . ^^^ A significant inverse relationship between plasma renin activity and age , independent of blood pressure , was shown in hypertensive patients and control subjects . 5 . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
Analysis of relationships between blood volume , vascular capacitance , cardiopulmonary and peripheral blood volumes , labelled albumin disappearance rate , plasma renin activity , blood pressure and age was performed in essential hypertensive males . 2 . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
Plasma catecholamines were raised in 70 % of ' high ' renin patients with primary hypertension ( group 2 ) , were related directly with age in normotensive females and were related inversely with catecholamine responses to postural stress in both normotensive and hypertensive subject ( P less than 0 01 ) . 3 . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
Renin and heart rate responses to exercise and beta receptor blockade diminished from high renin to normal and to low renin patients , effects which were blunted with increasing age . 3 . ^^^ Long term anti hypertensive propranolol effects correlated with pre treatment renin status , renin stimulation and its suppression by acute beta receptor blockade as well as with the exercise tachycardia and the patient ' s age . 5 . ^^^ The results suggest different adrenergic control mechanisms in renin sub types of essential hypertension , age being a modulating factor . . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
The incidence of low renin hypertension , when age and race are taken into account , is much lower than previously assumed . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
Also , peripheral plasma levels of aldosterone and plasma renin activity were determined in both the spontaneously hypertensive and the normotensive rats at 7 8 weeks of age . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
The findings emphasise the need to relate data from patients to age matched control values before attempting interpretation and suggest that sodium depletion is a more potent stimulator of renin aldosterone release than renovascular disease or renal scarring in children . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
In 5 volunteers with essential hypertension ( age between 32 and 48 years ) plasma renin activity ( PRA ) was determined and right heart catheterization and femoral artery pressure measurements were carried out at rest and during isometric exercise by handgrip . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
The stroke prone strain showed significantly higher plasma renin levels at and after seven months of age , while the stroke resistant strain showed no significant differences from the control at any age . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
In order to elucidate the main factors controlling plasma aldosterone in infancy and childhood , plasma renin activity ( PRA ) , plasma cortisol ( PC , as a parameter of ACTH activity ) , plasma aldosterone ( PA ) and serum sodium and potassium were measured simultaneously in 84 healthy children ( 62 recumbent , 22 upright ) ranging in age from 6 days to 16 years . 10 healthy male students served as adult controls . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
The effect of age and norepinephrine on renin release by rat kidney slices in vitro . ^^^ Basal renin release by rat kidney slices decreases with age in rats of SHR and Sprague Dawley strains . ^^^ In contrast , Kyoto Wistar rats ( from which SHR are derived ) demonstrate no decrease in renin release with age . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
Plasma renin activity as a function of age in two new strains of spontaneously hypertensive and normotensive rats . 1 . ^^^ Plasma renin activity was significantly higher in young spontaneously hypertensive than in normotensive rats of the same age ( 5 7 weeks ) . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
Potassium ( 100 mM ) enhanced this activity but sodium or calcium had no effect . 2 Uterine renin like activity was unchanged 24 h after bilateral nephrectomy . 3 Renin like activity in the uterus increased slowly from birth to 4 weeks of age and faster between the 4th and 8th week . 4 Ovariectomy caused a considerable fall in uterine renin like activity . 5 The following factors , known to affect renin secretion in the kidney , i . e . , hypovolaemia , sodium loading , adrenalectomy , administration of desoxycorticosterone acetate and injection of isoprenaline , had no effect on uterine renin like activity . 6 Stilboestrol , an oestrogen , caused a significant increase of uterine renin like activity . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
The groups were similar with respect to plasma renin activity , renin response to ultrafiltration , age , duration of dialysis , nerve conduction velocity , plasma protein concentration , hematocrit , dialysis weight change , resting heart rate , sex , race , blood pressure and heart rate response to cold pressor test , and 125I albumin plasma volume . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
The present study was undertaken to assess the influence of acute metabolic acidosis on the activity of renin angiotensin aldosterone system and renal function in a group of seven one week old neonates with mean birth weight of 2164 g ( range : 1300 3750 g ) and mean gestational age of 34 weeks ( range : 28 40 weeks ) undergoing oral NH4Cl load . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
Seventeen of these patients ( age 26 + / 7 years ) , so far untreated , were investigated prospectively for hormone levels ( renin , aldosterone , vasopressin ) , microalbuminuria , renal haemodynamics ( inulin and PAH clearance ) and signs of organ damage ( echocardiography , fundoscopy ) . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
As the mouse Ren 2d renin gene is integrated into their genome , they develop fulminant hypertension between 5 and 15 weeks of age , with blood pressure maxima of 300 mm Hg . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
Effect of oestradiol was studied on the angiotensin converting enzyme ( ACE ) a component of renin angiotensin system , in oviduct of immature quails of 15 days of age . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
Effects of age and posture on plasma active renin and plasma inactive renin in normal subjects . ^^^ To investigate the effects of age and posture on plasma active and inactive renin , we measured the plasma active renin concentration ( ARC ) and inactive renin concentration ( IRC ) in 81 healthy subjects . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
The influence of age on renal function and renin and aldosterone responses to sodium volume expansion and contraction in normotensive and mildly hypertensive humans . ^^^ To determine the effects of age on the responses of renin , aldosterone ( PA ) , sodium excretion , and renal function to provocative maneuvers , we performed volume expansion and contraction in 390 normotensive and 212 hypertensive subjects in the second to seventh decades of life . ^^^ Plasma renin activity decreased with age under basal , stimulated , and suppressed conditions ; the decrease was greater in hypertensives than in normotensive persons . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
These data were compared with age , serum potassium level , plasma renin activity ( PRA ) and in 14 patients with left ventricular mass , measured echocardiographically . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
The complex included evaluation of blood lipid spectrum ( HDL , LDL , VLDL , triglycerides ) , hemostasis ( coagulation , platelet aggregation , fibrinolysis ) , hormonal profile ( blood hydrocortisone , aldosterone , testosterone , estradiol , STH , FSH , LH , prolactin , plasma renin activity ) , central and intracardiac hemodynamics , ECG . 66 healthy men of advanced age served control . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
To determine whether high protein feeding throughout development affects renal growth , renal hemodynamics , and the intrarenal distribution of renin and its mRNA in the adult animal , male Wistar rats were fed diets containing either 20 % protein [ normal ( NP ) , n = 12 ] or 40 % protein [ high ( HP ) , n = 12 ] from weaning until studied at 6 or 12 wk of age . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
Effect of age and blood pressure on the heart rate , vasopressin , and renin response to hypoxia in fetal sheep . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
Plasma renin activity ( PRA ) declines with age in normal individuals , but the effect of age on plasma angiotensin 2 ( ANG 2 ) is less clear . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
The lack of the circadian rhythm for ANP along with the divergent changes in ANP and PRA 24 hr mean concentration of elderly subjects both suggest that ANP exerts with advancing age only a counterregulatory role on the tonic rather than the phasic release of renin . . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
Conversely , patients with low renin activity are protected from heart attack despite higher blood pressures and greater age . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
The plasma and adrenal renin angiotensin system in stroke prone spontaneously hypertensive rats ( SHRSP ) and Wistar Kyoto ( WKY ) rats were examined in animals at 5 , 11 , 18 , and 25 weeks of age . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
Comparing FH 2 patients with 88 patients with primary aldosteronism of other causes revealed no differences in mean age at presentation or at onset of hypertension , sex incidence , lowest recorded serum potassium , plasma aldosterone , plasma renin activity or adenoma size . 4 . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
The effects of prostacyclin infusion ( 6 . 7 + / 2 . 7 ng / kg / min , 3 to 10 ng / kg / min ) on blood pressure , plasma renin activity ( PRA ) , and 6 keto prostaglandin F 1 alpha ( 6 keto PGF 1 alpha ) were studied in 7 patients with essential hypertension ( 4 men and 3 women ) with a mean age of fifty eight + / eleven years ( forty six to seventy four years ) . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
The plasma aldosterone level and plasma renin activity ( PRA ) were very high 290 ng / ml and 100 ng / dl per hour , respectively ( normal range for this age 2 . 6 20 . 8 ng / ml and 1 . 2 2 . 7 ng / ml per hour , respectively ) . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
Plasma renin decreased with age in patients with renovascular hypertension and essential hypertension . ^^^ Stimulated plasma renin activity and the net increase in plasma renin activity after captopril administration in patients with essential hypertension showed a significant decrease with age . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
This age dependency of the renal RI and , hence , of the renal vascular resistance might be dependent on levels of active renin , as the maturational profile of the renal RI more closely parallels that of active renin than those of other renal functional parameters . . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
The antihypertensive effects of the renin inhibitor enalkiren were compared with those of the angiotensin converting enzyme inhibitor enalaprilat in 17 hypertensive patients ( 14 white , 3 black ; mean age 57 years ) , whose renin systems had been stimulated by diuretic pretreatment . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
Serum and urine sodium , plasma renin activity , serum ADH , cardiac index , effective renal plasma flow , and total blood volume were measured in seven burn patients ( mean age , total burn size , and postburn day : 32 years , 56 % , and 9 days , respectively ) . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
RESULTS The four randomised groups of patients had similar age , severity of heart failure ( NYHA class ) , pretreatment diuretic dosage , plasma renin activity , and serum electrolyte state . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
Blood pressure ( BP ) tended to be higher in the former group ( p less than 0 . 005 ) but age , urinary sodium excretion , plasma renin activity , and aldosterone levels or creatinine clearance were comparable . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
Age and reactivity of sympathetic and / or renin activity may play a major role in determining the response of cardiac mass to BP lowering . . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
Serum renin activity was measured in 35 women aged 18 57 ( mean age = 37 . 3 ) with Graves Basedow hyperthyreosis , before and after the thyrostatic treatment . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
These findings suggest that as the duration of diabetes and the age of the animal lengthens , there is a decrease in the number of cells expressing the renin gene . . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
The present study has demonstrated that in contrast to individuals with normal or high renin activity and of the same age and the same degree of heart failure , patients with its low levels are better protected against arrhythmias and severe and therapy resistant heart failure . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
Furthermore , membrane angiotensin 2 receptors were measured in trophoblastic tissues . 2 . ) Blood and tissue concentrations of total renin , active renin , angiotensin 2 and steroids are shown to increase with gestational age . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
Plasma concentrations of atrial natriuretic peptide and aldosterone and plasma renin activity were measured in patients with peripartum heart failure and in age matched healthy women post partum . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
The effectiveness of CEB might be explained by some characteristics of old age , such as elevated mean blood pressure , reduced plasma renin activity , blunted sympathetic activity , altered drug pharmacokinetics and so forth . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
We measured plasma ANP , plasma renin activity ( PRA ) , plasma aldosterone , serum estradiol 17 beta and progesterone concentrations in 103 normotensive women , either in premenopause ( n = 35 ; mean age : 24 years ) , in physiological menopause ( n = 34 ; mean age : 43 years ) or surgically induced menopause ( n = 34 ; mean age : 55 years ) . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
The relationship between renin responsiveness to furosemide and the antihypertensive effect of captopril in patients with normal renin essential hypertension were studied in 23 patients including nine men ( mean age , 41 years ) and 14 women ( mean age , 40 years ) . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
Nine variables were correlated with survival in the univariate analysis , including resistive index , age , hepatomegaly , blood urea nitrogen , serum creatinine , plasma sodium concentration , glomerular filtration rate , plasma renin activity and plasma concentration of antidiuretic hormone . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
Left ventricular structure and function were assessed with two dimensional targeted M mode echocardiography in 692 men with mild to moderate hypertension ( average blood pressure 153 / 100 mm Hg ) , and the data were compared in relation to obesity ( determined from body mass index ) , age , race , blood pressure , physical activity , plasma renin activity , urinary sodium excretion , hematocrit , heart rate and serum lipids . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
At the age of 42 , he showed hypertension ( 162 / 100mmHg ) , hypokalemia , metabolic alkalosis , low plasma renin activity ( PRA ) and normal plasma aldosterone concentration ( PAC ) in a supine posture . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
The factors examined included age , sex , systolic blood pressure , diastolic blood pressure , plasma renin activity , plasma aldosterone concentration , and sodium and potassium intake as determined by 24 hour excretion . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
Male and female progeny were tested at a prepubescent age ( postnatal day 28 ) by measuring 1 ) the stimulation of adrenocorticotropic hormone , corticosterone and renin by a maximally effective dose ( 0 . 5 mg / kg s . c . ) of the 5 HT1A agonist 8 hydroxy 2 ( di n propylamino ) tetralin ( 8 OH DPAT ) ; and 2 ) [ 3H ] 8 OH DPAT labeled 5 HT1A receptors and [ 3H ] paroxetine labeled 5 HT uptake sites in hypothalamus , cortex and midbrain . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
To evaluate the relationship between kallikrein and salt sensitivity in essential hypertension , active kallikrein excretion , plasma renin activity , atrial natriuretic peptide and aldosterone levels were evaluated in 37 male hypertensives ( mean age 43 . 3 + / 4 . 7 years ) after two weeks on a normal NaCl diet ( 120 mmol NaCl per day ) . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
Compared with whites plasma renin is low in blacks independently of age , the level of BP and dietary sodium consumption . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
Clinical and specific examination of 525 patients with special emphasis on ultrasonic , radionuclide and angiographic procedures , a captopril pharmaco radiological test , radioimmunoassay of renin in the renal vein and vena cava inferior provided the diagnosis of vasorenal hypertension ( VRH ) in 65 of them ( 30 males , 35 females at the age of 18 60 ) . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
The plasma renin activity declined with age in NT as well as in EH . ( ABSTRACT TRUNCATED AT 250 WORDS ) . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
In view of this , plasma catecholamines , fasting serum insulin ( IRI ) , urinary sodium excretion ( NaU ) , plasma renin activity ( PRA ) , and plasma aldosterone ( PA ) levels were assessed in young ( age less than 40 years ) normotensive ( n = 27 ) and hypertensive ( n = 14 ) subjects with central obesity and in lean normotensives ( n = 20 ) . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
To test the effects of aging , renin angiotensin system , and pressure on the arterial wall , 20 normotensive male WAG / Rij rats were killed at 6 , 12 , 24 , and 30 mo of age and compared with similar groups treated with an angiotensin ( ANG ) converting enzyme inhibitor ( ACEI ) , perindopril . ^^^ Plasma renin activity decreased with age and increased with ACEI . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
Cardiovascular responses to cold pressor test and associated changes in blood concentrations of renin , aldosterone , and catecholamines were measured in 11 type 1 diabetic patients with microalbuminuria ; 11 type 1 diabetic patients with normoalbuminuria matched for age , duration of diabetes , metabolic control ; and in nine normal control subjects . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
At the age of 4 months significantly lower renal renin activity was observed in spontaneously hypertensive rats than in both normotensive rat strains , Wistar Kyoto and Brown Norway . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
Attempts to rationalise the treatment of hypertension on the basis of pathophysiological and clinical characteristics of patients , such as renin profile and age , have had minimal success in the past . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
It was hypothesized that the OZR would possess low plasma renin values and an increased vascular responsiveness to angiotensin 2 , and therefore , the renin angiotensin system ( PRA , active renin , inactive renin , renal renin content , and plasma angiotensinogen ) and vascular reactivity in OZR at 10 and 24 wk of age were investigated . ^^^ PRA and renin concentration , inactive plasma renin , and renal renin content were all significantly ( P < 0 . 05 ) reduced in OZR when compared with age matched lean controls . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
The diagnostic utility of post captopril renal vein renin ( RVR ) measurements was quantitated in 43 patients ( mean age 62 , range 41 to 77 years ) undergoing aortography to rule out renovascular hypertension ( RVHT ) , and then compared with that of pre captopril RVR measurements . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
Antihypertensive efficacy of the calcium channel blocker , nilvadipine , was investigated in 21 patients with essential hypertension in relation to the intracellular sodium concentration ( [ Na ] 1 ) in erythrocytes and clinical variables , such as age , body weight , pretreatment blood pressure and plasma renin activity . ^^^ The hypotensive effect of nilvadipine was positively correlated with age ( r = 0 . 67 , p < 0 . 01 ) and inversely correlated with plasma renin activity ( r = 0 . 62 , p < 0 . 01 ) , but was not correlated with erythrocyte [ Na ] 1 or any other indices . ^^^ In conclusion , the antihypertensive efficacy of nilvadipine was predictable by age and renin status , but not by erythrocyte [ Na ] 1 . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
The relationship between pressure dependent renin release and mean arterial pressure ( MAP ) level was assessed in normotensive intact ( n = 10 ) , sympathectomized ( guanethidine at 1 13 wk of age ; n = 8 ) , and renal denervated ( 1 wk before the study ; n = 6 ) rats under normal salt diet . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
There were no differences in age , duration of haemodialysis , blood pressure and the levels of plasma renin activity , noradrenaline , and parathyroid hormone between groups . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
The Na K Cl cotransport activity in red blood cells from essential hypertensive men with low ( n = 8 , mean age 42 + / 4 years ) or normal renin activity ( n = 4 , mean age 43 + / 3 years ) , and in normotensive men with normal renin activity ( n = 7 , mean age 38 + / 4 years ) has been evaluated by means of a recently developed 23Na nuclear magnetic resonance ( NMR ) method . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
Previous research on the ontogeny of sodium appetite in the rat has shown that sodium deficit first engenders sodium intake at 12 days of age , whereas direct stimulation of the brain renin angiotensin system by intracranial injection of renin increases intake of NaCl solution as early as 3 days postnatally . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
It was observed that the microalbuminuric group ( 24 . 5 % of the total population ) was characterized by a higher systemic arterial pressure , a lower level of high density lipoprotein cholesterol , and similar mean values of age , duration of hypertension , glomerular filtration rate , renal plasma flow , filtration fraction , and plasma renin activity when compared with normoalbuminuric subjects . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
To analyze the status of the renin angiotensin system in hypertensive transplant recipients on cyclosporine , we prospectively explored 21 cardiac ( CTR : 52 + / 8 . 2 yr ) and 12 liver ( LTR : 45 + / 10 yr ) transplant recipients on a normal salt diet with 19 normotensive controls in the same age range . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
A decline in the function of the renin angiotensin aldosterone system may induce adaptive changes in response to angiotensin 2 ( ANG 2 ) with age . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
In order to evaluate the mid term effects of amlodipine , a 1 , 4 dihydropyridine calcium antagonist , as well as its effects on the renin angiotensin aldosterone system ( RAAS ) , on water and electrolyte balance , on urinary excretion of albumin ( UAE ) and on lipid metabolism , thirteen hypertensive patients ( 2 M , 11 F , mean age 54 years ) were studied in the course of 24 weeks of therapy with amlodipine at 5 10 mg / day . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
The following parameters were studied in a group of patients suffering from essential arterial hypertension complicated by chronic renal insufficiency ( CRI ) , mean age = 64 . 31 + / 1 . 84 , with creatinine clearance ( CrC ) ranging between 30 and 60 ml / min : blood pressure ( systolic and diastolic arterial pressure ) , heart rate , plasmatic renin activity ( PRA ) , plasma levels of aldosterone ( ALDO ) both in clino and orthostatism , as well as some metabolic parameters . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
Age related changes in the renin angiotensin aldosterone system and the sympathetic nervous system in patients with essential hypertension ] . ^^^ The aim of this study was to evaluate age , plasmatic renin activity ( PRA ) , plasma aldosterone levels and the total quantity of urinary catecholamines ( TOT . ^^^ These data confirm the changes in the biological , hemodynamic and endocrine profiles observed in elderly hypertensive patients in comparison to young hypertensive patients , and suggests that age may be an important predictive factor of the activity of both the renin angiotensin and sympathetic nervous system which appear to be closely connected and gradually attenuated by age . . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
Despite suppressed kidney and plasma renin , these animals develop fulminant hypertension between 5 and 15 weeks of age . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
Age related changes in the renin aldosterone system . ^^^ Age related changes in the renin aldosterone system in normal humans are well documented . ^^^ There is a close temporal and directional relationship between the age related decrease in plasma renin activity and the age related decrease in plasma aldosterone . ^^^ The primary clinical importance of age related changes in the renin aldosterone system relates to its impact on the proper classification of an individual ' s renin aldosterone profile when attempting to diagnose a clinical condition ( e . g . low , normal or high renin hypertension ) . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
There were no between groups differences relative to age , plasma renin activity , plasma aldosterone , plasma antidiuretic hormone , plasma osmolality , urine sodium or potassium excretion , or creatinine clearance . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
RESULTS The three groups had similar age , severity of heart failure , diuretic dose before treatment , plasma renin activity , and serum electrolyte state . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
The size of renin mRNA did not change with increasing age . ^^^ However , the levels of renin mRNA in kidney RNA decreased 70 % after 12 months of age . . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
There was a significant age effect on renin mRNA levels ( F = 10 . 0 , P < 0 . 001 ) ; values increase significantly between 0 . 64 and 0 . 95 g ( P < 0 . 005 ) , remain elevated in the newborns ( P < 0 . 05 ) , and subsequently decline in adulthood ( P < 0 . 005 ) . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
We conclude that salt sensitivity is increased with age in essential hypertensives , and renin angiotensin system might be involved in it . . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
We measured blood pressure and plasma renin activity on 100 progeny , 54 males and 46 females , greater than 44 months of age with an abbreviated tether protocol and software program for data collection . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
Two hundred forty four consecutive patients ( mean age 61 years ) , including 123 who had technically valid renal vein renin ( RVR ) analysis and 121 without RVR data , underwent technically successful percutaneous renal artery angioplasty ( PTRA ) . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
In caucasian salt replete essential hypertension neither age nor plasma renin activity were major factors . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
A multivariate analysis of graft survival using patient race , sex , age , transplant number , current and maximum plasma renin activity , donor race , cold ischemia time and HLA mismatch , the need for dialysis , and the presence of rejection as independent variables . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
However , although the incidence of heart failure rises rapidly with age , relatively little is known about activation of the renin angiotensin and sympathetic nervous system in patients with heart failure over the age of 75 years . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
Angiotensin peptides and plasma levels of renin , angiotensinogen , ACE , and aldosterone were measured at 10 and 20 weeks of age . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
Plasma renin concentration was not elevated , whereas urinary excretion of aldosterone was increased at any age in the low sodium group compared with that in the control group . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
In 52 female F 2 rats ( 25 to 27 weeks of age ) derived from SHR and Wistar Kyoto rats , we determined blood pressure , renin mRNA concentration in the adrenal gland , plasma renin activity , plasma aldosterone concentration , and genotype of the renin gene . ^^^ Paradoxically , the SHR allele of the renin gene or renin gene locus confers a lower rate of aldosterone synthesis at 25 to 27 weeks of age , the mechanism of which remains to be determined . . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
Stepwise multiple linear regression analysis showed that changes of plasma norepinephrine , insulin sensitivity index , plasma renin activity , and age were significant predictive factors for the change of mean blood pressure after weight loss . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
METHODS : A retrospective analysis was performed regarding age and sex of the patients , duration of hypertension , family history of hypertension , preoperative blood pressure , plasma aldosterone concentration ( PAC ) , plasma renin activity ( PRA ) and efficacy of spironolactone on blood pressure between both groups . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
The single dose pharmacokinetics of nefazodone ( NEF ) and its metabolites hydroxynefazodone ( HO NEF ) and m chlorophenylpiperazine ( mCPP ) were examined in 12 healthy younger subjects < or = 55 years of age ( YNG ) , 12 elderly subjects > or = 65 years of age ( ELD ) , 12 patients with biopsy proven hepatic cirrhosis ( HEP ) and 12 patients with moderate renal impairment ( REN ) , ClCR 20 60 ml . min 1 . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
The three groups did not differ in age , education , body mass index ( BMI ) , estimated aerobic fitness , resting HR , cardiac preejection period ( PEP ) and PEP : LVET ( left ventricular ejection time ) ratio , 24 h Na or K excretion , or fasting lipids , insulin or plasma renin activity . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
The activity of the renin angiotensin system as well as the ability of the kidney to retain sodium following salt restriction are reduced with age . ^^^ The relationship between these age related changes in renal function and the renin gene expression was presently investigated . ^^^ The intrarenal content of renin mRNA did not differ between 10 and 30 month old animals , suggesting that the transcriptional rate of the renin gene is unchanged with age . ^^^ These data suggest that the age related decrease in renal concentration of renin is linked to a modification in the rate of translation of renin mRNA , or to an alteration in the protein maturation . ^^^ The difference in adaptation to the early phase of salt restriction with age should not be linked to changes in renin gene transcription , but more likely to a change in the tissue response to the local renin angiotensin system . . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
Captopril renin test ( CRT ) and captopril angioscintigraphic test ( CAT ) were simultaneously performed in 130 patients with arterial hypertension ( 72 women , 58 men , average age 48 years ) and suspension for renovascular hypertension ( RVH ) in initial renal angioscintigraphy . 16 positive CAT results and 26 positive CRT results according to Muller qualification as well as 31 positive results according to Frederickson qualification were obtained . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
These transgenic rats develop fulminant hypertension at an early age despite low levels of renin in plasma and kidney . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
Subjects were white , 55 years of age or younger , and living with the patient and their child ( ren ) aged 7 to 16 years old . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
This study was designed to examine the changes in kidney morphometry during gestation in fetuses that were either appropriate or small for gestational age and the relationship between umbilical vein plasma active renin and kidney morphometry . 2 . ^^^ The mean umbilical vein active plasma renin concentration at delivery was significantly higher ( P < 0 . 05 ) in the small for gestation age group ( 274 . 4 + / 32 . 9 mu units / ml plasma ) than in the appropriate for gestational age group ( 164 . 9 + / 28 . 3 mu units / ml plasma ) . ^^^ Umbilical vein plasma renin levels were higher in small for gestational age fetuses . ^^^ The findings of slow fetal renal growth rate and associated high renin concentrations seen in small for gestational age fetuses could be implicated in an irreversible reno vascular pathology leading to adult hypertension . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
Plasma renin activity and plasma prorenin are not suppressed in hypertensives surviving to old age . ^^^ An age related decline in plasma renin activity ( PRA ) has been described in normotensive and hypertensive subjects . ^^^ We therefore investigated whether that pattern of renin and prorenin suppression was apparent in white hypertensives and normotensives surviving to an older age . ^^^ However , since an inverse relationship between PRA and age has been reported , it remains to be determined whether the renin / prorenin parameters were suppressed at any time or if normal renin and normal prorenin patients preferentially survive to an old age . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
SUBJECTS AND METHODS : In 383 hospitalized Caucasian essential hypertensives ( 198 men , 185 women ) of mean age 44 + / 0 . 5 years and mean clinic blood pressure 170 . 3 + / 0 . 95 / 103 . 4 + / 0 . 47 mmHg , metabolic parameters , serum creatinine level ( Cs ) , creatinine clearance rate ( Ccs ) , 24 AER and plasma renin activity ( PRA ) were measured . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
Age related changes in plasma aldosterone and corticosterone concentrations as well as in plasma renin activity in response to 10 days of sodium deprivation were studied in old as compared to adult male Long Evans rats . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
In 24 patients with essential hypertension , ranging in age from 30 to 68 years , renin status , renal hemodynamics , and sensitivity of BP to steady state changes in salt intake were assessed . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
Normalization of plasma aldosterone , electrolytes , and renin concentrations was achieved at the age of 9 months . . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
To test the hypothesis that renal sympathetic nerves influence the renal and renin responses to furosemide in conscious newborn animals , experiments were carried out in chronically instrumented lambs with either bilateral renal denervation ( denervated , n = 7 , age = 13 + / 3 ( SD ) days ) or intact renal sympathetic nerves ( intact , n = 6 , age = 13 + / 4 ( SD ) days ) , at least 4 days after surgery . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
Included in the analysis were : blood pressure , age , sex , body mass index , endogeneous creatinine clearance , smoking and plasma renin activity . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
PATIENTS AND METHODS : From a population of 114 patients with documented primary aldosteronism , we selected 23 never treated patients ( 12 males , 11 females ; 11 tumoral , 12 non tumoral ) and compared them to patients with never treated essential hypertension with low renin ( supine plasma renin activity < 1 ng / ml per h , n = 23 ) or normal renin ( supine plasma renin activity between 1 and 4 ng / ml per h , n = 23 ) , matched for age , body mass index , mean arterial pressure , renal function and known duration of hypertension . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
In normally reared control animals , renal renin and liver angiotensinogen mRNA decreased between 6 and 30 postnatal days of age . ^^^ In contrast , in the central nervous system , angiotensinogen mRNA increased between 6 and 30 days of age , and renin mRNA remained stable . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
Plasma ( PV ) and red cell volumes ( RCV ) , 24 h ambulatory blood pressure ( BP ) , 24 h natriuresis and morning plasma aldosterone , renin activity and atrial natriuretic peptide in 11 men with a mean age of 47 y ( range 37 55 ) , apnoea index ( AI ) of 55 ( 22 106 ) , body mass index of 36 ( 30 43 ) and seated BP of > or = 140 / 90 mmHg without any medication were measured . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
To study the relations between neuropeptide Y ( NPY ) and age , gender , blood pressure ( BP ) and risk factors for cardiovascular disease and the renin angiotensin system , we performed a population based study through random selection of 220 subjects ( 49 % men ) . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
METHODS AND RESULTS : Estrogen status and components of the renin angiotensin system were examined in a population based sample of postmenopausal women and age matched men . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
Developmental studies demonstrate age dependent elevation of renin activity in TGR ( mRen 2 ) 27 rats . ^^^ Systolic blood pressure and left ventricular mass index ( LVMI ) were measured in transgenic heterozygote and normotensive Sprague Dawley control rats at 25 , 35 , 45 , 55 , 65 , and 75 days of age together with determinations of plasma active renin and prorenin , and renal and adrenal tissue renin , which were assayed at pH 6 . 5 , 7 . 4 , and 8 . 5 . ^^^ Plasma active renin of the transgenic rats , measured at physiological pH , was significantly higher from 55 days of age , increasing in parallel with blood pressure and remaining significantly higher than controls at all age groups tested . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
Sixteen postmenopausal women with essential hypertension , with a mean age of 59 years and diastolic blood pressures of 95 to 115 mm Hg , were enrolled in a 12 week , single blind study to determine the effects of losartan on blood pressure , renal and extrarenal PG production , plasma renin activity ( PRA ) , plasma aldosterone , and routine biochemical parameters . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
These results , coupled with findings that the mRen 2 transgene product converts rat angiotensinogen more effectively than endogenous rat renin , that the TGR may have high circulating mouse renin levels which increase with age , and the fact that high circulating prorenin concentrations are present in these TGR , shed light on the kidney ' s role in the blood pressure elevating mechanisms of TGR . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
To determine whether pretreatment plasma renin activity ( PRA ) , without accompanying 24 h urine sodium , can predict myocardial infarction ( MI ) , the PRA levels of 2 , 902 hypertensive patients [ white ( 38 % ) , male ( 65 % ) , median age 55 years ] , with mean entry blood pressure ( BP ) of 150 / 97 mm Hg were examined . ^^^ In a Cox survival analysis only renin , age , sex , smoking , LVH , and cholesterol were significantly ( P < . 02 ) related to MI occurrence . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
METHODS : We measured the plasma concentrations of digoxin like immunoreactive substances ( by a fluorescence polarisation immunoassay ) and natriuretic peptides , aldosterone , renin , and antidiuretic hormone ( by radioimmunoassay ) in ten patients with aneurysmal subarachnoid haemorrhage , ten patients undergoing elective craniotomy for cerebral tumours , and 40 healthy controls of similar age and sex distribution . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
In comparison with normal subjects of the same age ( group N , n = 13 ) , those from group E did not differ in body mass index , plasma lipid profile , fasting glucose , insulin and catecholamine ( CA ) concentrations , but had increased erythrocyte sodium content , slightly elevated plasma renin activity and cortisol level . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
DESIGN : A population based sample of 615 middle age subjects was studied by standardised echocardiography ; anthropometric measurements ; and biochemical quantification of renin , pro renin , angiotensinogen , angiotensin converting enzyme ( ACE ) , and aldosterone . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
The aim of the present study was to analyse age dependent changes in renal haemodynamics and renal renin secretion which could be of pathophysiological importance in the course of the disease . ^^^ We investigated glomerular filtration rate ( GFR ) , renal blood flow ( RBF ) , renal vascular resistance ( RVR ) , plasma renin activity ( PRA ) , the autoregulatory behaviour of RBF and the pressure dependent plasma renin activity in conscious PKD rats compared with age matched controls . ^^^ The basal plasma renin activity was significantly ( P < 0 . 05 ) lower in 3 month old PKD than in old PKD and age matched controls . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
Effects of LV mass , adiposity , race , age , physical activity , height , weight , sodium excretion , plasma renin activity and heart rate were examined . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
Age , weight , and baseline blood pressure , heart rate , urinary sodium excretion , plasma renin , angiotensin 2 , and aldosterone concentrations did not differ between genotypes . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
Univariate regression analysis revealed a significant correlation between LV mass and averaged cyclosporine levels , but no correlation between LV mass and blood pressure , cold ischemic time , acute rejection , age , body mass , blood pressure , plasma catecholamine levels , or plasma renin activity . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
At the age of 12 months , haptoglobin phenotypes and plasma active renin concentration were determined as well as random urine evaluation of aldosterone , cAMP , dopamine and digoxin like immunoreactive substances ( DLIS ) . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
A population based study was performed in order to study the interrelationships of the circulating components of the renin angiotensin system during basal conditions and their relations to blood pressure ( BP ) , age and gender . ^^^ Plasma renin activity ( PRA ) correlated negatively with age ( r = 0 . 30 , P < 0 . 0001 ) , but immunoreactive active renin ( IRR ) and angiotensin 2 did not . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
Renal , but not extra renal , renin mRNA levels declined with age . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
Since an elevated urinary albumin excretion ( UAE ) has been indicated as a negative prognostic marker for cardiovascular diseases in essential hypertensives , we evaluated UAE in 50 male patients with mild to moderate essential hypertension ( mean age 46 . 3 + / 4 . 4 years ) , characterized as low renin ( LR ) ( n = 14 ) , modulating ( M ) ( n = 20 ) , and NM patients ( n = 16 ) according to their renin profile and ability to modulate the aldosterone response to a graded infusion of angiotensin 2 . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
Plasma renin activity remained high until about the age of 8 years , after which it decreased to almost within the normal range . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
The study groups included 13 patients with low renin essential hypertension ( average age 43 . 5 + / 16 . 2 years ) , 16 patients with normal renin essential hypertension ( 46 . 5 + / 13 . 4 years ) , 11 patients with high renin essential hypertension ( 40 . 7 + / 13 . 8 years ) and 12 healthy subjects ( 43 . 1 + / 11 . 4 years ) . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
Post natal development of plasma and urine osmolality , as well as plasma renin activity , aldosterone and cortisol levels were studied in calves between 1 and 9 months of age . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
The response of blood pressure and plasma renin activity ( PRA ) 1 h after 50 mg captopril administration were evaluated in 82 inpatients with untreated essential hypertension ( 42 men , 40 women ; mean age + / SD : 52 + / 13 years ; range : 27 to 79 years ) in relation to ACE genotypes . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
Because nonhemodynamic factors seem to play a fundamental role in the development of LVH , the present study was undertaken to investigate the relationship between the predialysis renin level and the echocardiographically determined cardiac structure in stable hemodialysis patients , matched for other parameters known to participate in the development of LVH , such as age ; gender ; body mass index ; interdialytic weight gain ; heart rate ; systolic , diastolic , and mean arterial BP ; hematologic and biochemical profile ; vascular access ; adequacy of dialysis ; nutritional status ; and period of follow up . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
At the adult age , LH rats differed from LN rats by elevated BP , left ventricle weight , and vascular resistances , especially in the kidneys , associated with lower kidney renin and prorenin contents . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
In the present study , the components of this pathway were investigated in left ventricles of hearts from hypertensive transgenic rats overexpressing the mouse renin gene [ TG ( mREN 2 ) 27 ] in comparison to age and weight matched Sprague Dawley control rats . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
We have studied a patient with severe hypertension , low renin and aldosterone , and a chronic hypokalemic alkalosis at age 4 . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
The hypertension was defined as severe , resulting in stroke before age 50 years , featuring normal renin , aldosterone , and catecholamine responses , and did not appear to be salt sensitive . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
The renin angiotensin system changes with age , but it is unclear how renal responses to angiotensin 2 ( Ang 2 ) evolve as an animal matures . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
Multivariate analysis adjusting for systolic blood pressure , body mass index , and age revealed that renin and ANP were independently associated with LV mass index ( p < 0 . 05 each ) . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
We measured cardiac volumes , diastolic and systolic functions , systemic ( Doppler echocardiography ) and renal hemodynamics , intrarenal sodium handling ( lithium clearance method ) , plasma and urinary cGMP , plasma renin concentration , and plasma aldosterone level in six healthy volunteers ( mean age , 33+ / 3 years ) receiving CNP ( 2 and 4 pmol / kg per minute for 1 hour each ) in a single blind , placebo controlled , random order , crossover study . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
Oral administration of cisapride caused a two fold increase in the plasma aldosterone levels ( 182 . 6 + / 28 . 0 % in high renin state and 203 . 4 + / 38 . 6 % in low renin state ; P = 0 . 659 between the means of two states ) without affecting the plasma renin levels , Scatterplot of percentile aldosterone increment against age distribution demonstrated that the R square were very low ( 0 . 039 for high renin and 0 . 009 for low renin state ) . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
The two groups of patients were similar in sex , age , systolic / diastolic blood pressure , supine / upright plasma renin activity , supine / upright aldosterone , tumor size . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
However , prenatal glucocorticoid exposure did not alter vascular sensitivity to noradrenaline , angiotensin 2 and adrenocorticotropic hormone in these sheep at any of the ages studied , nor did it affect basal or adrenocorticotropic hormone induced concentrations of cortisol or basal plasma renin concentrations in the lambs at any age . 4 . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
Following 6 weeks of double blind treatment with placebo or 0 . 25 to 16 mg / day trandolapril , an analysis of drug effect on trough blood pressure ( BP ) stratified by age , gender , weight , pre treatment plasma renin activity , and trandolaprilat concentration was performed . ^^^ There were no observable differences based on age , gender or measurements of the renin angiotensin aldosterone axis . ^^^ In conclusion , neither age , gender or plasma renin activity influenced anti hypertensive response to angiotensin converting enzyme inhibition in African Americans . . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
These calcium antagonists are effective in lowering blood pressure and reducing anginal episodes in African Americans and whites , regardless of age or renin level . . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
METHODS AND RESULTS : Using data from a large population based sample of 1488 siblings having a mean age of 14 . 8 years and belonging to the youngest generation of 583 randomly ascertained three generation pedigrees from Rochester , Minn , we carried out variance components based linkage analyses to evaluate the contribution of variation in four renin angiotensin system gene regions ( angiotensinogen , renin , angiotensin 1 converting enzyme , and angiotensin 2 receptor type 1 ) to interindividual variation in systolic , diastolic , and mean arterial pressure . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
MATERIALS AND METHODS : Activity of plasma renin ( APR ) , angiotensin converting enzyme ( ACE ) , plasma levels of angiotensin 2 ( AII ) and vasopressin ( VP ) , serum concentration of aldosteron ( AS ) were measured by radioimmunoassay and enzyme immunoassay in 21 PPH patients with circulatory failure ( age 34 . 7 + / 2 . 1 years ) , 11 patients with NYHA functional class 2 3 , 10 with class 4 , and 10 control subjects ( age 29 . 8 + / 1 . 5 years ) . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
There were no differences in age , blood pressure , retinopathy grade , presence of proteinuria , or resting plasma renin activity ( PRA ) among the hypertensive patients with the 2 , ID , and DD genotypes . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
The best combinations of predictor variables contained mean arterial pressure , plasma renin activity , creatinine concentration and age ( r 2 = 14 . 4 % , P = 0 . 37 ) . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
METHODS : Hypertensive transgenic ( mREN 2 ) 27 rat ( TGR ) that exhibit increased tissue renin expression were administered streptozotocin ( STZ , diabetic ) or citrate buffer ( non diabetic ) at six weeks of age , and sacrificed 4 and 12 weeks later . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
The relationship between age and plasma neurohormones ( norepineprine , epinephrine , dopamine , renin , aldosterone , atrial natriuretic peptide , N terminal atrial natriuretic peptide , and endothelin ) , and age and prognosis was examined . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
Thirty four patients ( 65 . 3+ / 3 . 3 years of age , mean+ / SEM ) with hyperkalemia ( serum potassium > 5 . 0 mEq / L ) had measurement of their renin aldosterone system . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
Significant associations between the 825T allele and diastolic blood pressure , plasma renin , and prorenin levels ( inverse ) , and the aldosterone to renin ratio persisted after adjustment for age , gender , body mass index , and systolic blood pressure . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
These animals develop fulminant hypertension and cardiac hypertrophy at an early age despite low levels of renin in the plasma . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
There was no correlation between MA and age , sex , body mass index , systolic or diastolic blood pressure , plasma renin activity , serum ACE levels or left ventricular index . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
METHODS : Total renin concentrations ( TRC ) were measured with a time resolved immunofluorometric assay in 38 patients with IDDM ( age 34 ( SD 7 ) years , duration of disease 22 ( 7 ) years , serum creatinine 95 ( 15 ) mumol / l , urinary albumin excretion rate ( UAER ) 207 ( 829 ) micrograms / min , HbA1c 8 . 5 % ( 1 . 2 % ) ) , and in 13 matched normal subjects . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
METHODS : This systematic review of the literature investigated genetic variation in the renin system according to race , sex and age . ^^^ In five studies ( n=989 ) on the renin gene , the Hind 3 and Taq 1 polymorphisms varied with the groups ' average age , whereas the Bg 1 , Bg 2 and Hind 3 but not Taq 1 sites differed according to race . ^^^ CONCLUSION : With adjustments applied for the subjects ' enrollment group and the methods of genotyping , genetic polymorphism in the renin system varies according to race and age , but not sex . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
DESIGN AND METHODS : Plasma levels of renin , prorenin , angiotensinogen , ACE and aldosterone , as well as angiotensinogen and ACE genotypes were determined in 228 men and 168 women ( age 52 65 years ) , who had participated in a population survey in southern Germany . ^^^ After adjustment for sex , age and blood pressure , the T 235 allele of the angiotensinogen gene was also related to lower plasma prorenin ( P < 0 . 03 ) and renin ( P < 0 . 01 ) levels , but not to plasma ACE and aldosterone . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
Adducin genotype was significantly ( R2=0 . 11 , F=6 . 5 ; P < 0 . 01 ) and directly related to fraction excretion of lithium ; gender , age , urinary Na+ , urinary uric acid , mean blood pressure , and plasma renin activity were not related . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
In the study usefulness of active renin ( AR ) measurement instead of plasma renin activity ( PRA ) in the diagnosis of reno vascular hypertension ( RVH ) was evaluated . 42 patients with arterial hypertension ( 17F , 25M ; mean age 45 + 12 years ) and suspicion on RVH on the ground of the abnormal result of the preliminary renal angioscintigraphy were qualified to the study . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
The prognostic value for a good outcome was evaluated using age , creatinine clearance , plasma renin activity , plasma aldosterone , and Pugh score . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
SUBJECTS AND METHODS : Exchangeable sodium , plasma and blood volumes , and catecholamine , renin , and aldosterone levels were assessed in 10 patients with Type 2 diabetes mellitus who had orthostatic hypotension and control groups of 40 diabetic patients without orthostatic hypotension and 40 normal subjects of similar age and sex . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
The two groups were comparable in terms of age , gender , plasma renin activity , human leukocyte antigen mismatches , and cause of renal failure . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
Twenty four hour BP ( SpaceLabs SL 90207 ) , 24 h urine excretion of catecholamines , plasma renin activity and plasma aldosterone concentration were therefore determined in 10 nephrotic patients with normal serum creatinine levels ( group A , serum creatinine 1 . 0+ / 0 . 2 mg / dl ) , in 10 nephrotic patients with increased serum creatinine levels ( group B , serum creatinine 2 . 4+ / 0 . 9 mg / dl ) and in 20 controls matched in respect of age and BP . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
Tsukuba hypertensive mice ( THM ) carrying both the human renin and angiotensinogen genes and C57BL / 6J control mice 2 to 3 months of age were fed with either a western or normal diet for 14 weeks . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
No association was observed with blood pressure , body mass index , age , plasma renin , angiotensinogen , angiotensin converting enzyme , cholesterol , triglycerides , or HDL or LDL cholesterol . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
Renin aldosterone system and atrial natriuretic peptide during anesthesia in orthopedic patients over 80 years of age . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
Cardiac hypertrophy was shown to be related to age and gender with the copy number of mouse renin transgenes having an additive effect . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
Plasma PAI 1 antigen , tPA antigen , plasma renin activity , and aldosterone were measured in 25 normotensive subjects ( 19 white , 6 black ; 14 men , 11 women ; mean age 38 . 5+ / 1 . 8 years ; mean body mass index 25 . 3+ / 0 . 7 kg / m ( 2 ) ) during low salt intake alone ( 10 mmol Na / d ) , low salt intake + quinapril ( 40 mg PO bid ) , and low salt intake + losartan ( 50 mg PO bid ) . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
METHODS : We studied plasma renin , prorenin , and four polymorphic markers of the renin gene in 199 patients with IDDM and DN , and in 192 normoalbuminuric IDDM controls matched for age , sex , and duration of diabetes . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
RESULTS : Age , blood pressure , body mass index , 24 h urinary sodium excretion and plasma renin activity were in the 2 groups with and without hormone replacement therapy . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
METHODS : Ninety nonobese , nondiabetic , nonhyperlipidemic patients with mild to moderate essential hypertension ( 67 males , 23 females ; mean age 51 . 4 + / 6 . 2 years ) were divided into low renin ( LR ) , normal renin ( NR ) , and high renin ( HR ) subgroups according to individual PRA while they were on a constant NaCl intake ( 120 mmol NaCl / day ) . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
There was no correlation between gestational age , Na ( + ) K ( + ) ATPase , plasma renin activity and aldosterone values either in the preterm or term babies . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
PATIENTS AND METHODS : In the 12 patients with hyperaldosteronism , retrospective analysis of clinical ( age , sex , blood pressure ) , biochemical ( plasmatic and urinary potassium , plasmatic aldosterone , plasma renin activity , and plasmatic aldosterone / renin activity ratio ) , and morphological ( computed tomography , magnetic resonance , and norcholesterol scintigraphy ) data was performed . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
In this study of 37 healthy human volunteers , distributed among three groups ( group 1 : n = 13 , age range 20 39 years ; group 2 : n = 13 , age range 40 59 years ; group 3 : n = 11 , age range 60 68 years ) , we evaluated the influence of age on some of the vasoactive systems such as plasma renin activity , urinary kallikrein , plasmatic prokallikrein , plasmatic kallikrein , and plasmatic kininogen on RPF and creatinine clearance ( Ccr ) in response to an acute oral protein load ( 1 g / kg body weight ) . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
Similarly , in response to early exposure to cold stress and maternal deprivation , there was an increase in plasma renin activity levels of congenital learned helpless rats with age of presentation to either stressors . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
The objectives of the present study were to examine the life circumstances , childhood abuse , and types of homicidal acts of 48 mothers who killed / attempted to kill their child ( ren ) under age 12 between 1970 96 in Finland . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
We measured plasma and platelet magnesium concentrations , plasma epinephrine and norepinephrine , and plasma aldosterone and renin concentrations in normotensive ( NT Ob , n = 19 , BMI 35 . 7 + / 7 . 4 kg / m2 , WHR 0 . 92 + / 0 . 05 ) and hypertensive ( HT Ob , n = 11 , BMI 35 . 2 + / 3 . 6 kg / m2 , WHR 0 . 93 + / 0 . 07 ) obese subjects , and in a group of age and sex matched lean controls ( n = 14 , BMI 23 . 1 + / 1 . 8 kg / m2 , WHR 0 . 79 + / 0 . 05 ) . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
DESIGN : Plasma renin activity ( PRA ) was measured in 38 patients with stable chronic heart failure ( 21 male , 17 female ; mean ( SD ) age 71 ( 6 ) years , range 59 82 years ) on chronic diuretic treatment alone . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
Plasma renin activity was significantly increased by low sodium diet and significantly decreased by high sodium diet , with no significant difference between the responses of the 2 age groups . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
PATIENTS AND METHODS : 62 patients with TS , age 5 . 4 22 . 4 years , had 24 h ABPM ( ambulatory blood pressure monitoring ) , echocardiography , renal imaging and measurement of recumbent plasma renin activity ( PRA ) . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
A strong relationship was found with age ( r= 0 . 54 , P < 10 ( 4 ) ) and plasma renin activity ( r=0 . 32 , P < 10 ( 4 ) ) in women but not in men . ^^^ We conclude that age , gender , and plasma renin are strong determinants of the aldosterone response to Ang 2 , with strong sibling correlations in men and postmenopausal women . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
Renin and heart rate responses to haemorrhage are age dependent in conscious lambs . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
Untreated transgenic rats overexpressing the human renin and angiotensinogen genes ( dTGR ) feature hypertension and severe left ventricular hypertrophy with focal areas of necrosis , and die at age 7 weeks . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
We tested the hypothesis that endothelin ( ET ) ( A / B ) receptor blockade with bosentan ( 100 mg / kg by gavage after age 4 weeks ) ameliorates cardiac and renal damage by decreasing inflammation in rats harboring both human renin and angiotensinogen genes ( dTGR ) . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
Plasma renin activity and plasma angiotensin 2 level was equivalent in the 9 and 12 week old SHRSP and the WKY rats ; both parameters , however , were elevated in 24 week old SHRSP as compared with age matched control . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
Sex and age adjusted IMT did not differ between quartiles of renin sodium profile . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
RESULTS : There were no differences between transplant patients , with and without PTE , with respect to weight , age , sex , blood pressure , serum creatinine , circulating renin , angiotensin 2 , and Epo levels . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
No changes in mean arterial pressure , or plasma angiotensin 2 , aldosterone , and renin activity levels were noted at either gestational age . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
Age , weight , number of palliative operations , plasma renin activities and pulmonary to systemic flow ratios ( 3 . 5 vs . 3 . 5 ) were not significantly different prior to Captopril or Propranolol therapy . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
Total renin minus renin is the PP level ; PP was correlated with the presence of ROP , stage of ROP , gestational age , birth weight , and postnatal age . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
Renin immunostaining was localized to the afferent arterioles , with a greater percentage of arterioles staining in rats with CHF ( 55 . 3 % + / 2 . 1 % ) than in sham operated ( 43 . 9 % + / 1 . 9 % ) or normal age controls ( 37 . 6 % + / 2 . 2 % ) . ^^^ Rats with CHF more frequently exhibited multiple bands of renin staining within a single arteriole ( 24 . 9 % + / 1 . 8 % ) as compared with sham operated ( 13 . 3 % + / 1 . 9 % ) and normal age controls ( 11 . 3 % + / 1 . 4 % ) . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
Plasma renin activity is significantly lower in black people compared with whites independent of age and blood pressure status . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
The following initial measurements were significantly ( P < 0 . 002 ) associated with subjects who had died compared with subjects known to be alive : age at study , pulse pressure , systolic , diastolic , and mean arterial pressures , hypertension , salt sensitivity , baseline renin levels , and body mass index ( but not body weight ) . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
Other univariate predictors of greater blood pressure responses included black race , female gender , higher pretreatment blood pressure , older age , lower waist to hip ratio , and measures of lower renin angiotensin aldosterone system activity . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
In a multiple regression model including age , sex , body mass index , and changes in systolic pressure , plasma renin activity and plasma aldosterone and urine volume , salt excretion resulted as the stronger independent predictor of urinary ADM ( r = 0 . 33 , P = . 01 ) . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
Moreover , a 5 fold increase of renin mRNA was observed in hearts of HTG rats between day 2 and the third month of age . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
Plasma renin activity was suppressed by a high salt intake in all age groups , and baseline values declined with advancing age . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
All participants had a child ( ren ) under 4 years of age and were currently enrolled in a primary care or family HIV clinic . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
RESULTS : At the univariate analysis , New York Heart Association ( NYHA ) class ( p < 0 . 0001 ) , age ( p < 0 . 0001 ) , male gender ( p < 0 . 0001 ) and plasma renin ( p < 0 . 0001 ) significantly related with peak Vo 2 . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
In 130 subjects with IDDM , aged 15 . 2+ / 4 . 8 years and diabetes duration 7 . 3+ / 5 years , and in 48 controls of comparable age , UFC , urinary endothelin ( UET 1 ) , urinary albumin , HbA1c , and plasma renin were determined . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
Doppler indices of renal vascular resistance were closely related to the duration of the disease , age , and plasma renin activity . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
We observed that candesartan increased renin mRNA in all rats at all ages , the amplitude of stimulation being inversely related to age . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
CONCLUSIONS : The data indicate the effects of renal denervation on renin mRNA expression in the kidney are age dependent and that the fetus in late gestation has a mechanism for maintaining renin mRNA levels after denervation , which is absent or nonfunctional in the adult . . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
METHODS : Serum potassium , leptin , aldosterone , insulin levels and plasma renin activity were measured and hyperinsulinaemic euglycaemic clamp was performed in 11 patients with PA and 11 healthy age , gender and body mass index ( BMI ) matched subjects . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
Although differences in race , age and measures of the renin angiotensin aldosterone system ( RAAS ) have been associated with variation in blood pressure response to hydrochlorothiazide , whether these characteristics make additive contributions to predicting response has not been established . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
Although certain demographic features including age , ethnicity , and diabetes mellitus predispose to low renin hypertension , these factors account for only a minority of cases . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
Plasma renin concentrations at this age were lower in the uninephrectomized lambs ( P < 0 . 05 ) . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
We measured BP and plasma levels of neurohumoral factors ( norepinephrine [ NE ] , epinephrine , renin , and arginine vasopressin [ VP ] ) during the 70 degree head up tilt test ( 10 min supine and 15 min tilting ) in 120 older subjects ( mean age 71 years ) who had sustained hypertension as determined by ambulatory BP monitoring . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
METHODS AND RESULTS : Concentrations of atrial natriuretic peptide ( ANP ) , brain natriuretic peptide ( BNP ) , endothelin 1 ( ET 1 ) , renin , aldosterone , norepinephrine , and epinephrine were determined in 53 adults with congenital heart disease , comprising 4 distinct anatomic subgroups ( 29 female ; 33 . 5+ / 1 . 5 years of age ; New York Heart Association class 2 . 0+ / 0 . 1 , mean+ / SEM ) and 15 healthy control subjects ( 8 female ; 32 . 3+ / 1 . 3 years of age ) . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
A regression analysis showed that CVI ( s ) was predicted by the PQ duration , supine plasma renin activity , plasma aldosterone , and age , which collectively accounted for approximately 36 % of CVI ( s ) variance . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
MATERIAL / METHODS : In 31 patients with essential hypertension ( EHP 14 F , 17 M , age 44I14 years , BMI 29 . 3I6 . 4 kg / m2 ) and 8 healthy subjects ( NHS 4 F , 4 M , age 37 ( 17 years , BMI 25 . 3I6 . 6 kg / m2 ) plasma leptin concentration , plasma renin activity ( PRA ) , and 24 hour urinary sodium excretion ( UNa ) were evaluated twice : first on a diet containing 100 120 mmol sodium per day and after 8 hours overnight bed rest , and a second time after 3 days of dietary sodium restriction ( 10 20 mmol daily ) and 3 hours in upright position . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
METHODS : The responses of renal and systemic vascular resistances ( RVR and SVR ) and plasma noradrenaline and renin ( NOR and PRA ) to systemic NO stimulation and inhibition were studied in patients with grade 1 essential HT and age and sex matched NT subjects . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
The following measures were found to be significantly associated with the risk for death : blood pressure ( systolic , diastolic , mean arterial , and pulse pressures ) , hypertension , age , salt sensitivity , baseline renin levels ( inverse ) , and body mass index ( but not body weight ) . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
RESULTS : Proteinuria remained the single most important predictor of long term renal function ; other predictors included baseline GFR , blood pressure , plasma renin activity , lipid profile , age , weight / body mass index , and diabetes duration . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
Age and gender matched wild type ( + / + ) and homozygous null mice ( / ) were administered captopril for 7 days , and plasma and renal renin levels and renal renin mRNA expression were measured . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
Recent clinical trials have demonstrated effective antihypertensive activity in hypertension , independent of age , renin and salt status or ethnic origin , and have also highlighted the potential for vasopeptidase inhibition as a new therapeutic modality for the treatment of CHF . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
The study groups included 10 patients with low renin essential hypertension ( average age 42+15 years ) , nine patients with medium renin essential hypertension ( 46+13 years ) , 11 patients with high renin essential hypertension ( 42+14 years ) and 12 healthy subjects ( 43+11 years ) . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
According to a multiple logistic regression analysis , the age and baseline plasma renin activity adjusted relative risk ( odds ratio ) for the lack of a depressor response conferred by the D allele ( assuming an additive effect ) was 2 . 72 [ 95 % confidence interval ( CI ) , 1 . 07 6 . 91 ; p = 0 . 034 ] ; for DD genotypes , as compared with the DI and 2 genotypes ( assuming that the D allele is recessive ) , it was 11 . 7 ( 95 % CI , 2 . 25 60 . 6 ; p = 0 . 003 ) . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
Diagnosis may be made at any age in most forms of low renin hypertension . . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
No differences in age , fat mass , homeostasis model assessment ( HOMA ) , the summation of insulin ( sigmaIRI ) , plasma renin activity ( PRA ) or 24 h norepinephrine excretion ( 24hU NE ) were observed between the hypertensive ( HT ) group ( n = 31 ) and normotensive ( NT ) group ( n = 71 ) before weight loss , but the basal serum leptin was significantly higher in the HT ( 16 . 8 + / 1 . 1 ng / ml ) than in the NT group ( 15 . 2 + / 0 . 8 ng / ml ) , after adjusting for abdominal total fat . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
Additional factors associated with resolution of hypertension based on univariate analysis included younger age , shorter duration of hypertension , higher preoperative ratio of plasma aldosterone concentration to plasma renin activity , and higher urine aldosterone level ( P < 0 . 05 ) . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
The rise in BP was not dependant on age , the change in plasma renin activity or weight . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
Also , plasma renin activity was significantly lower in the female offspring of hypertensive mothers at 10 weeks of age ( P < 0 . 05 ) , suggesting that development of the renin angiotensin system was altered . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
Female TGR ( mREN 2 ) 27 rats harboring the mouse Ren 2 renin gene were treated with Flutamide ( specific antagonist of the androgen receptor , 30 mg / kg per day ) starting at 4 weeks of age . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
In group B , microalbuminuria correlated with ambulatory BP , and plasma renin activity failed to decrease with chronological age . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
METHODS : In nine hypertensive male patients ( age 46 64 years ) undergoing diagnostic renal artery angiography and renal vein catheterization to determine plasma renin activity ( PRA ) , a 3F Doppler catheter was positioned in the renal veins using a 7F guide catheter with a `` basket ' ' shaped tip . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
In a protocol in which animals were matched for age , at 11 . 5 wk , terminal systolic blood pressure and urine protein excretion were elevated in SHAM and OVX+E2 rats compared with OVX rats ; blood urea nitrogen , renal microvascular and glomerular lesions , and plasma renin concentration were elevated in OVX+E2 relative to SHAM or OVX rats . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
Because it is known that renin angiotensin system ( RAS ) activation and defective glucose control contribute to adverse renal outcomes , we examined renal responses to high glucose and to manipulation of the RAS in adolescents ( mean age 14 + / 2 years ) with uncomplicated type 1 diabetes , segregated into two groups on the basis of the presence or absence of normal N / D BP ratio . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
Arterial hypertension was observed at about 4 months of age and was associated with high levels of plasma renin activity and circulating angiotensin , and also with changes in renal Doppler ultrasonography . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
METHODS : In 227 consecutive patients with hypertension ( mean age + / SD : 53 . 3 years + / 13 . 4 , 126 men ) , we measured : PWV , LAD , LVPWT , mean 24 hours SBP , plasma renin activity , and plasma aldosterone and catecholamine levels . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
At 5 , 10 , and 15 days of age , renal tissue renin activity and Ang 2 concentration were measured by radioimmunoassay . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
To date , we have chosen several target transcription factors such as NFkappaB ( nuclear factor kappaB ) and E2F to prevent the progression of diseases , and negative regulatory element ( NRE ) for the renin gene and angiotensinogen gene activating element ( AGE ) for the angiotensinogen gene to examine the molecular mechanisms of gene expression . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
We studied the nocturnal plasma concentration of ACTH , cortisol , renin and aldosterone , and sleep EEG in 7 medication free patients with depression ( 1 male , 6 females , age : ( mean + / SD ) 53 . 3 + / 14 . 4 yr . ) and 7 age matched controls ( 2 males , 5 females , age : 54 . 7 + / 19 . 5 yr . ) . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
Plasma norepinephrine . epinephrine , renin angiotensin system activity , ANP , BNP , and serum interleukin 6 ( IL 6 ) and tumor necrosis factor ( TNF ) alpha were measured in 84 CHF patients ( age , 59 + / 1 years , LVEF , 36 + / 1 % ) and 34 controls . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
Calcium antagonists are effective in hypertensive patients of all ethnic groups , irrespective of age , dietary salt intake , salt sensitivity status or plasma renin activity profile . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
FMD was negatively and significantly correlated with plasma aldosterone ( r= 0 . 38 , P=0 . 0006 ) , 24 hour urinary aldosterone ( r= 0 . 49 , P < 0 . 0001 ) , and ratio of plasma aldosterone to plasma renin activity ( r= 0 . 43 , P < 0 . 0001 ) but was independent of blood pressure , age , and body mass index . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
Age dependence of the levels of plasma norepinephrine , aldosterone , renin activity and urinary vanillylmandelic acid in normal and essential hypertensives . ^^^ Primary hyperaldosteronism was not detected among the normokalemic essential hypertensives at any age using aldosterone / plasma renin activity ratio as a primary screening method . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
We evaluated the effects of a subpressor ADMA dose on NO production , renal hemodynamics , sodium handling and active renin and noradrenalin plasma concentrations in 12 healthy subjects ( age 26 + / 1 year ) using a double blind placebo controlled study design . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
In a multivariate logistic regression containing renin status ( low renin vs normal / high renin ) , aldosterone on a high sodium diet , age , body mass index , gender , race , duration of hypertension , systolic and diastolic blood pressure and salt sensitivity only low renin status on a low sodium diet ( P=0 . 019 ) and serum aldosterone on a high sodium diet ( P=0 . 04 ) were significant predictors of LVH . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
Variables considered included age , gender , race , body mass index ( BMI ) , hypertension status , blood pressure , basal RPF , creatinine clearance , serum insulin , serum glucose , serum high density lipoprotein ( HDL ) , serum triglycerides , and plasma renin activity ( PRA ) . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
As other targets , we focused on negative regulatory element ( NRE ) for the renin gene and angiotensinogen gene activating element ( AGE ) for the angiotensinogen gene to examine the molecular mechanisms of gene expression , AP 1 and ets 1 . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
At 4 weeks of age , the kidneys of male offspring were harvested to measure cortical AT 1 and AT 2 receptor expression , 125I Ang 2 glomerular binding , tissue renin activity , tissue Ang 2 and plasma aldosterone concentrations . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
About one half of double transgenic rats ( dTGR ) overexpressing the human renin and angiotensinogen genes die by age 7 wk of terminal heart failure ( THF ) ; the other ( preterminal ) one half develop cardiac damage but survive . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
When rendered sodium hungry by ivc renin or by sodium depletion , these sucklings prefer urine and NH4Cl to NaCl , dilute urine , or an NaCl and KCl mineral mix equimolar to urine ; however , by 18 days of age , urine and NH4Cl are no longer preferred to NaCl . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
In this study , ACE levels and renin concentrations were measured in the sera of 16 patients with RA ( median age : 45 ( 26 69 ) , male / female : 3 / 13 ) , 13 patients with osteoarthritis ( OA ) ( median age : 55 ( 28 72 ) , male / female : 5 / 8 ) , and 11 healthy adults ( median age : 44 ( 35 70 ) , male / female : 6 / 5 ) . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
Results were compared according to age , gender , the number of HLA matches , plasma renin activity levels , etc . , with 52 patients ( control ( C ) group ) under cyclosporin A , mycophenolate mofetil and steroids treatment . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
There were no significant differences in the age of recipients ( 42 . 3+ / 11 . 3 vs . 39 . 4+ / 14 . 1 ) , as well as in HLA matching ( 2 . 2 / 6 M vs . 2 . 2 / 6 M ) , in the number retransplanted patients ( 10 . 3 % vs . 10 . 4 % ) and in highly sensitized patients ( plasma renin activity > 50 . 0 % ) ( 5 . 1 % vs . 4 . 8 % ) between those groups . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
In multivariate analysis , serum bilirubin , renin , ET 1 , PGE 2 , decreased urinary sodium excretion and age were identified as predictors of renal dysfunction . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
After an infusion of AGE RSA , renal expression of angiotensinogen , ACE , renin , and angiotensin receptor type 1 were increased significantly ( all P < 0 . 01 ) , and ACE activity was elevated . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
Systolic , diastolic , and mean BP values and plasma renin activity concentration were obtained in 422 young adults who were born with a gestational age ( GA ) < 32 weeks . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
METHODS AND RESULTS : Concentrations of N terminal pro atrial natriuretic peptide , N terminal pro brain natriuretic peptide ( NT proBNP ) , endothelin ( ET ) 1 , renin , aldosterone , adrenalin , and noradrenalin were determined in 50 adults ( mean age , 27 . 8 + / 1 . 7 years [ + / SEM ] ; 26 women ) with tetralogy of Fallot ( TOF ) after surgical repair ( New York Heart Association functional class 1 . 1 + / 0 . 1 ) . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
After adjustment for other predictors of the renal plasma flow response to captopril using a multivariate linear regression model , there was a highly significant relationship between age and plasma renin activity adjusted body mass index and the renal plasma flow response to captopril ; however , a quadratic model provided a substantially better fit ( r=0 . 55 ; P < 0 . 0001 ; P=0 . 03 versus linear correlation ) . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
Age may affect this balance by influencing blood pressure ( BP ) or renin responses . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
Age did not significantly affect plasma arginine vasopressin or aldosterone levels , but renin activity was only 8 % in 31M WR rats relative to 3M WR ( P < 0 . 05 ) . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
Renal interlobar artery parameters with duplex Doppler sonography and correlations with age , plasma renin , and aldosterone levels in healthy children . ^^^ OBJECTIVE : The objectives of this study were to compare and make correlations between age and Doppler parameters of the interlobar arteries , including synchronously obtained plasma renin and aldosterone levels and to obtain new normative data regarding acceleration time in healthy children from neonates to 16 years . ^^^ Age had a negative correlation with the RI , PI , plasma renin levels , and aldosterone levels and correlated positively with acceleration time . ^^^ We showed that the age dependency of the RI was directly related to that of plasma renin and aldosterone levels in healthy children in whom Doppler parameters and blood analysis were evaluated synchronously . . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
Disparities in health care and good health between African Americans and other populations while established in the literature are traditionally based on socioeconomic measures of race , income , age , and education ( Bailey , 2000 ; Lillie Blanton , Brodie , Rowland , Altman and McIntosh , 2000 ; Ren and Amick , 1996 ; Watson , 2001 ; Weinick , Zuvekas , and Cohen , 2000 ) . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
In women , there was a significant positive correlation between the left ventricular mass index and age , as well as plasma renin activity and smoking . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
The regression model included presence / absence of sympathetic autonomic neuropathy , age , diabetes duration , presence / absence of hypertension , baseline SBP and neuro hormonal parameters ( plasma adrenaline , noradrenaline , plasma renin activity , and aldosterone ) . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
The beat to beat continuous heart rate , hematocrit ( Hct ) changes during HD , serum levels of nitric oxide , plasma levels of catecholamine , renin , endothelin ( ET 1 ) , cardiac output ( CO ) , and peripheral vascular resistance ( PVR ) were measured before and after HD in patients prone to develop intradialysis hypertension ( n = 30 ) and from age , sex matched control HD subjects ( n = 30 ) . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
In multivariable models , plasma aldosterone was associated positively ( P < 0 . 05 ) with blood pressure in older individuals ( interaction with age , P < 0 . 05 ) and with waist circumference in men ( interaction with sex , P < 0 . 05 ) and negatively with high density lipoprotein cholesterol , in particular in individuals with elevated urinary potassium excretion ( interaction with urinary potassium , P < 0 . 05 ) ; plasma renin activity was significantly associated with triglycerides and fasting blood glucose . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
At the age of 12 weeks p47phox / mice showed increased plasma renin activity as analyzed by radioimmunoassay ( 14 . 5+ / 1 . 8 ng / mL / h vs . 9 . 6+ / 1 . 7 ng / mL / h , P < 0 . 05 , n=10 ) and enhanced angiotensin converting enzyme ( ACE ) activity in the kidney and aorta as measured by Hip His Leu cleavage ( 7 . 6+ / 0 . 8 vs . 4 . 8+ / 0 . 9 nmol / L His Leu / mg protein , P < 0 . 05 , n=5 ) compared to wild type mice . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
In age and sex adjusted models , several biomarkers were related to baseline brachial artery diameter ( PAI 1 , CRP , urine albumin creatinine ratio ) , baseline mean flow ( N ANP , BNP , PAI 1 , CRP , aldosterone ) , FMD ( N ANP , PAI 1 , CRP , renin ) , and reactive hyperemia ( BNP , PAI 1 , CRP , renin , urine albumin creatinine ratio ) . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
They developed a Bartter like syndrome characterized by a mild phenotype : hypokalemia occurred only at the age of 22 years ; it was corrected with small doses of oral potassium in one twin , while the other twin needed no potassium supplements to maintain borderline levels of plasma potassium ; alkalosis was absent ; plasma renin and aldosterone production were not markedly activated . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
Homology search for the cloned gene revealed that the GlcNAc 2 epimerase was identical with renin binding protein ( RnBP ) in porcine kidney ( Inoue , H . , Fukui , K . , Takahashi , S . , and Miyake , Y . ( 1990 ) J . ^^^ That GlcNAc 2 epimerase is a RnBP was confirmed by its ability to bind porcine kidney renin and mask its protease activity . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
We have developed a new assay method for GlcNAc 2 epimerase activity using a system of N acyl D hexosamine oxidase coupled with peroxidase and employed this method to study the effects of renin on GlcNAc 2 epimerase activity . ^^^ The recombinant human ( rh ) RnBP existed as a dimer and its GlcNAc 2 epimerase activity was strongly inhibited by the purified renin concomitant with the formation of RnBP renin heterodimer , so called high molecular weight ( HMW ) renin . ^^^ These results indicate that renin is an inhibitor of GlcNAc 2 epimerase , and the renin RnBP heterodimer HMW renin is an inactive form of both renin and GlcNAc 2 epimerase activities . . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
On the other hand , porcine renin inhibited recombinant GlcNAc 2 epimerase activities . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
The purified chimeric enzymes had GlcNAc 2 epimerase activity and inhibited renin activity in a dose dependent manner . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
Amino acid residues conferring the nucleotide binding properties of N acetyl D glucosamine 2 epimerase ( renin binding protein ) . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
Human renin binding protein is the enzyme N acetyl D glucosamine 2 epimerase . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
Identification of cysteine 380 as the essential residue for the human N acetyl D glucosamine 2 epimerase ( renin binding protein ) . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
Tissue specific regulation of renin binding protein gene expression in rats . ^^^ Rat gene for renin binding protein ( RnBP ) was shown to be expressed in the kidney , adrenal gland , brain , lung , spleen , ovary , testis , and heart . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
Modulation of active renin secretion by renin binding protein ( RnBP ) in mouse pituitary AtT 20 cells transfected with human renin and RnBP cDNAs . ^^^ To investigate the role of renin binding protein ( RnBP ) in renin metabolism , RnBP expression plasmid , which was constructed to express human RnBP under the control of mouse mammary tumor virus long terminal repeat , was transfected into mouse pituitary AtT 20 cells together with the expression plasmid encoding human renin . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
Leucine zipper motif in porcine renin binding protein ( RnBP ) and its relationship to the formation of an RnBP renin heterodimer and an RnBP homodimer . ^^^ An apparent leucine zipper motif was recognized in the predicted amino acid sequence of porcine kidney renin binding protein ( RnBP ) by analysis of the nucleotide sequence of a cDNA encoding the protein ( Inoue , H . , Fukui , K . , Takahashi , S . , and Miyake , Y . ( 1990 ) J . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
Molecular cloning and sequence analysis of a cDNA encoding a porcine kidney renin binding protein . ^^^ A complementary DNA encoding a renin binding protein ( RnBP ) has been isolated from a porcine kidney cDNA library by immunological screening of in vitro translation products from the cDNAs . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
Biosynthesis of a renin binding protein . ^^^ The biosynthesis of a porcine renin binding protein ( RnBP ) , which specifically binds to renin and forms an inactive high molecular weight renin , was investigated . mRNAs from various porcine tissues were used to investigate in vitro protein synthesis . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
Renal cortical high molecular weight renin ( Mw : 60 , 000 ) of the dog is a complex of renin ( low molecular weight renin ; Mw : 40 , 000 ) and a renin binding protein . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
A study on renin binding protein ( RnBP ) in the human kidney . ^^^ We purified , from human kidney , a protein that reacts with rabbit anti porcine kidney renin binding protein ( RnBP ) antiserum by trapping with porcine kidney renin . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
Purification of high molecular weight ( HMW ) renin from porcine kidney and direct evidence that the HMW renin is a complex of renin with renin binding protein ( RnBP ) . ^^^ Sodium dodecyl sulfate polyacrylamide gel electrophoresis of the HMW renin showed two protein bands , of which one was identified as renin from the electrophoretic mobility and the other was the protein , assigned as renin binding protein ( RnBP ) , that was insolubilized by acidification . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
Properties of renin binding protein . ^^^ Hog renal renin binding protein could bind homologous and non homologous renin but could not bind human renal renin . ^^^ Renin binding protein was only detected in the kidney and pituitary in which renin is found in relatively high concentration . ^^^ Most renin binding protein was recovered in the cytosol fraction and was not associated with sedimentable subcellular organelles . ^^^ A renin secreting tumor ( Juxtaglomerular cell tumor ) in human kidney produced not only renin but also renin binding protein in a very large quantity . . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
Specific distribution of renin binding protein in rat and dog kidney . ^^^ Localization of renin binding protein in the renal cortex of the rat and dog was investigated . ^^^ These results indicate that the renin binding protein is located in the tubules of the cortex , but not in the glomeruli of the kidney . . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
A 56 , 000 dalton renin binding protein in hog kidney is an endogenous renin inhibitor . ^^^ Renin binding protein ( RBP ) in hog kidney was characterized and identified as a renin inhibitor . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
Demonstration of the formation of renin and renin binding protein complex using high performance liquid chromatography . ^^^ A high performance liquid chromatograph equipped with the newly developed gel , TSK G3000SW , was used to study the interaction between renin and renin binding protein ( RBP ) . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
Structure and function of renin binding protein . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
Renin binding protein ] . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
Bound prorenin was displaced by rat and human renin or prorenin but not by the prosequence of rat prorenin , angiotensin 1 or 2 , rat or human angiotensinogen , the renin inhibitor SQ 30697 , atrial natriuretic factor , amylase , insulin , bovine serum albumin , hemoglobin , heparin , lysozyme , ovalbumin , cytochrome C , pepsin , pepsinogen , ribonuclease A , mannose 6 phosphate , alpha methyl mannoside , gonadotropin releasing hormone , or an antibody to hog renin binding protein . these results demonstrate specific binding of prorenin to a site in rat tissues , herein named ProBP , that also binds renin . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
A specific renin binding protein has been identified in cardiac tissue . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
Human renin binding protein : complete genomic sequence and association of an intronic T / C polymorphism with the prorenin level in males . ^^^ The role of renin binding protein ( RnBP ) in human ( patho ) physiology , despite its biochemical characterization , is as yet unclear . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
Structure of the gene encoding rat renin binding protein . ^^^ The gene encoding renin binding protein was isolated from a Sprague Dawley rat genomic DNA library and the exon intron boundaries and transcription initiation sites were identified . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
A BsII PCR / RFLP in the renin binding protein ( RnBP ) gene on canine chromosome 10 . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
MEASUREMENTS : Gene expression of angiotensinogen , renin , renin binding protein , angiotensin converting enzyme ( ACE ) and angiotensin 2 ( ang 2 ) receptor type 1 in human preadipocytes ; ACE protein and ang 2 production of human adipose tissue stromal cells differentiated or not in primary culture . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
MATERIALS AND METHODS : In order to explore the expression of renin angiotensin system genes in human adipose tissue and adipocytes , total RNA was isolated from whole adipose tissue ( subcutaneous and omental ) or cultured adipocytes ( mammary ) and subjected to reverse transcriptase polymerase chain reaction with primers specific for human angiotensinogen , renin , renin binding protein , angiotensin converting enzyme , chymase and type 1 and type 2 angiotensin receptors . ^^^ Furthermore , we found expression of the chymase and renin binding protein genes in these samples . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
Normal blood pressure and plasma renin activity in mice lacking the renin binding protein , a cellular renin inhibitor . ^^^ In renal extracts , some renin is present as `` high molecular weight renin , ' ' a heterodimeric complex of renin with the 46 kDa renin binding protein ( RnBP ) , also known as N acyl D glucosamine 2 epimerase . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
The expression of renin binding protein and renin in the kidneys of rats with two kidney one clip hypertension . ^^^ OBJECTIVE : To test the hypothesis that renin binding protein ( RnBP ) is involved in modulating the intracellular processing or release of renin , we examined the expression of RnBP in clipped and contralateral kidneys of rats with two kidney one clip hypertension , and in left and right kidneys from sham operated control rats . ^^^ Renin binding protein is expressed mainly in renal tubules and collecting ducts unlike renin , which is expressed in the glomerular afferent arteriole . ^^^ CONCLUSION : Renin binding protein expression is unchanged between clipped and contralateral kidneys . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
Assignment of the gene encoding renin binding protein ( Renbp ) to rat chromosome Xq 37 by in situ hybridization and radiation hybrid mapping . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
MEASUREMENTS : Analysis of polymorphisms in genes coding for angiotensinogen ( AJT 704T > C ) , angiotensin 2 receptor 1 ( AGTR 1 1166A > C ) , renin ( REN 2646G > A ) , renin binding protein ( RENBP 61T > C ) , alpha adducin ( ADD 1 1378G > T ) , beta 2 adrenergic receptor ( ADRB 2 46A > G , 79C > G ) , and angiotensin 1 converting enzyme ( ACE I / D ) was performed by polymerase chain reaction and restriction fragment length polymorphism analysis . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
Renin binding protein ( RnBP ) is an endogenous renin inhibitor originally isolated from porcine kidney . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
Urine retinol binding protein ( RBP ) , N acetyl beta D glucosaminidase ( NAG ) , albumin , bacteriuria , systolic blood pressure , glomerular filtration rate ( GFR ) , peripheral plasma renin activity ( PRA ) and the degree of renal scarring were measured in each subject ; 20 had bilateral and 35 unilateral renal scarring ; 5 were hypertensive and none were in renal failure . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.50798514
Levels of aldosterone were significantly correlated with levels of renin in all horses ( r = 0 . 62 , P less than 0 . 001 ) but not with those of cortisol , and renin was negatively correlated with age in male horses ( r = 0 . 54 , P less than 0 . 05 ) . 0.50798514^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.80036819
The purified RnBP formed a single precipitin line with the antiserum prepared with the purified HMW renin as antigen , which is RnBP renin complex ( Takahashi , S . , et al . ( 1983 ) J . 0.80036819^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
Atrial natriuretic factor increased with age in women but not in men ( r = 0 . 60 , p less than 0 . 001 ) , and plasma renin activity decreased ( r = 0 . 35 , p less than 0 . 02 ) . ^^^ Thus , in women , increase in LV chamber size with age and associated changes in LV systolic function , atrial natriuretic factor levels and plasma renin activity suggest plasma volume expansion related to the aging process . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
Renal renin secretion was examined in renal superficial cortical slices from spontaneously hypertensive rats ( SHR ) and Wistar Kyoto rats ( WKY ) at 4 wk ( prehypertensive ) , 6 wk ( early hypertensive ) , and 12 wk ( established hypertension ) of age . ^^^ Angiotensin 2 ( ANG 2 ) resulted in a significant reduction in renin release in both SHR and WKY at 10 ( 7 ) M in all age groups . ^^^ The ANG 2 induced percent change in renin release from control of SHR was less compared with WKY rats at 10 ( 8 ) and 10 ( 9 ) M at 4 wk of age . ^^^ These data document increased basal renin release and ANG 2 binding sites in proximal tubular BBM in 4 wk SHR compared with age matched WKY rat . ( ABSTRACT TRUNCATED AT 250 WORDS ) . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
The purpose of this study was to examine the relationship between the variability of awake ambulatory blood pressure and the level of plasma renin activity ( PRA ) in age matched samples of untreated hypertensive white men . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
To test the prognostic value of plasma renin activity prospectively , we determined the pretreatment renin sodium profile of 1717 subjects with mild to moderate hypertension ( mean age , 53 years ; 36 percent white ; 67 percent men ) in a systematic work site treatment program . ^^^ Renin profiles , obtained by plotting plasma renin activity against the urinary excretion of sodium , were classified as high ( 12 percent of the subjects ) , normal ( 56 percent ) , and low ( 32 percent ) , and there were expected variations according to age , sex , and race . ^^^ As adjusted for age , sex , and race , the incidence of myocardial infarction per 1000 person years was 14 . 7 among the subjects with a high renin profile , 5 . 6 among those with a normal profile , and 2 . 8 among those with a low profile ( rate ratio for high vs . low , 5 . 3 ; 95 percent confidence interval , 3 . 4 to 8 . 3 ) . ^^^ The independent association of a high renin profile with myocardial infarction ( but not with stroke or noncardiovascular events ) was affirmed by Cox analyses ( rate ratio for high vs . normal plus low , 3 . 2 ; 95 percent confidence interval , 1 . 2 to 8 . 4 ) after adjustment for race , sex , age at entry , serum cholesterol level , smoking status , electrocardiographic evidence of left ventricular hypertrophy , blood glucose level , body mass index , history of cardiovascular disease or treatment , blood pressure , and use of beta blockers . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
We examined factors ( blood pressure , plasma renin activity , and age ) influencing the antihypertensive response in essential hypertensive patients given 240 mg / day of slow release diltiazem in an unblinded study after a placebo run in period . ^^^ Subjects provided a range of diastolic blood pressures ( 90 to 115 mm Hg ) , of age ( 31 to 70 years ) , and of plasma renin activity ( 0 . 1 to 2 . 7 ng angiotensin I / ml / hr ) on a 70 to 150 mEq sodium diet . ^^^ Multiple linear stepwise regression of change in blood pressure versus age , plasma renin activity , and baseline blood pressure showed baseline blood pressure was the only predictor of response ( p = 0 . 0002 ) . ^^^ We conclude that patient age and plasma renin activity are not clinically significant predictors of antihypertensive response to diltiazem in hypertension . . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
When maintained on Stroke Prone Rodent Diet and saline , plasma renin activity of untreated SHRSP surviving until 14 . 5 weeks of age was markedly increased ( 29 . 1 + / 9 . 4 ng Ang I / mL / h ) compared with either untreated SHRSP ( 9 . 2 + / 2 . 5 ng Ang I / mL / h , P less than . 01 ) or Wistar Kyoto rats ( 3 . 5 + / 1 . 0 ng Ang I / mL / h , P less than . 01 ) maintained on standard diet and water . ( ABSTRACT TRUNCATED AT 250 WORDS ) . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
This antihypertensive effect was not related to baseline plasma renin activity levels or age . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
The present study was undertaken to assess the effects of acute metabolic acidosis on the activity of the renin angiotensin aldosterone system in 12 children with a mean age of 8 . 9 years who underwent NH4Cl loading test . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
Using multiple regression analysis , baroreflex sensitivity ( BS ) correlated positively to stroke volume index ( SVI ) and inversely to plasma renin activity ( PRA ) and to age : BS = 0 . 47 SVI 0 . 38 PRA 0 . 23 age + constant ( r = 0 . 74 ; p less than 0 . 0005 ) . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
At 3 year 6 month of age she suddenly developed hypertension ( the plasma renin activity was found to be 16 . 6 ng / m / hr . and the aldosterone 220 ng / dl ) . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
Her ratio of plasma renin activity to urinary aldosterone 18 glucuronide excretion was 1 . 7 after three days of sodium restriction , as compared with a ratio of 4 . 7 at the age of nine years ( normal range , 0 . 03 to 0 . 1 ) . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
Although short term administration of spironolactone raised renin and aldosterone markedly and lipids moderately ( possibly because of volume contraction ) , the present results show that perindopril and spironolactone are both safe and effective for treating hypertension at the age of 50 or older . . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
A mean sodium supplement of 2 . 2 mmol / kg per day ( range 0 . 5 4 . 9 ) , double the amount provided with feeds , was required to maintain plasma sodium concentration and plasma renin activity ( PRA ) in the normal range for age . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
Furthermore , there were only weak correlations between plasma renin activity and plasma norepinephrine and hemodynamic measurements , age , and renal function , indicating that activation of these systems is complex and determined by many other factors . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
There was no relation between the responsiveness to enalapril ( Emax or Ce 50 ) and patient age or plasma renin activity , but there was a significant positive correlation between Emax and the pretreatment blood pressure . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
The glomerular response in hypertensive patients was independent of age , duration of hypertension , blood pressure , plasma renin activity , urinary albumin excretion and retinal vascular alterations . 4 . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
Plasma renin concentration ( PRC ) and plasma and pulmonary angiotensin converting enzyme ( ACE ) concentration were measured in fetal and neonatal guinea pigs from 45 days gestational age ( GA ) until 21 days post partum . 2 . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
At baseline , subjects who developed hypertension had a greater left ventricular mass index than those who did not ( 92 + / 25 compared with 77 + / 19 g / m2 body surface area ; P less than 0 . 005 ) and higher 24 hour urinary sodium / potassium excretion ratio ( 3 . 6 + / 1 . 7 compared with 2 . 6 + / 1 . 4 ; P less than 0 . 04 ) ; there were no differences in race , initial age , systolic or diastolic blood pressure , coronary risk factors , or plasma renin activity . ^^^ In multivariate analyses , follow up systolic pressures in all subjects and in the 117 who remained normotensive were predicted by initial age , systolic blood pressure , black race , and sex adjusted left ventricular mass index ; final diastolic blood pressure was predicted by its initial value , plasma triglyceride levels , urinary sodium / potassium ratio , low renin activity , black race , and plasma glucose level . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
The levels of plasma renin , kidney renin , and kidney renin mRNA were examined in 6 and 9 wk old transgenic mice and were found to be significantly lower than their age matched non transgenic littermates and were nonresponsive to captopril treatment . ^^^ The levels of renal renin mRNA in transgenics and nontransgenic littermates were compared throughout ontogeny and were found to be equal in newborns , elevated 3 to 5 fold in 1 wk old transgenics , and yet decreased 10 fold by 6 wk of age in transgenic mice . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
There was no relationship between responsiveness ( in mmHg / ng / mL ) and patient age and plasma renin activity ; however , responsiveness during chronic treatment was directly correlated with the height of the starting blood pressure and the response to the first dose . . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
This difference in blood pressure at 25 weeks of age was due to reduced total peripheral resistance as determined by microsphere methods , but plasma renin activity and angiotensin 2 concentrations were not different . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
Pretreatment plasma renin ( as an indication of activation of the renin angiotensin system ) and the patient ' s age have been claimed to predict blood pressure fall . ^^^ Emax was not related to age or pretreatment renin , but was positively correlated with pretreatment blood pressure ( r = 0 . 69 ; p less than 0 . 01 ) . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
These characteristics have included physiologic factors , such as sodium sensitivity , plasma renin activity , or sympathetic nervous system activity , as well as demographic components , particularly age and race . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
Age dependent effects of chronic hypoxia on renin angiotensin and urinary excretions . ^^^ To evaluate the long term effects of chronic hypoxia on water balance , urinary electrolyte excretion , heart weights , systemic arterial pressure , and components of the renin angiotensin system , male Sprague Dawley rats were exposed to periods of simulated altitude of 10 , 000 ft up to 90 days of age beginning at 2 or 30 days of age . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
Increased ADH , which usually suppresses plasma renin activity , was associated with increased plasma renin activity of 11 55 ng angiotensin 1 / mL / h ( normal for age less than 10 ng angiotensin 1 / mL / h ) . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
Distribution of renin mRNA and immunoreactive renin ( IR ) was examined in kidneys of 1 mo old Sprague Dawley rats subjected to either sham operation ( n = 21 ) , left complete UUO ( n = 21 ) , or right uninephrectomy ( UNX , n = 16 ) at 2 days of age . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
Interrelations were investigated between blood pressure , plasma epinephrine ( E ) , norepinephrine ( NE ) , dopamine ( D ) , aldosterone , cortisol concentrations , active and inactive plasma renin activity ( PRA ) , and age in 21 normotensive subjects ( aged 20 60 years ) and in 25 patients ( aged 20 63 years ) with essential hypertension ( EH ) . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
Plasma Renin Activity ( PRA ) was determined in a group of 50 Cameroonian newborns and 50 Cameroonian children aged 1 15 years under resting conditions in order to establish baseline values , and also to investigate the relationship between PRA distribution , and blood pressure levels , age , or body weight . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
To develop a screening test for identification of renovascular hypertension , the blood pressure and plasma renin concentration responses to an oral test dose of captopril ( 6 . 25 mg ) were studied in 47 hypertensive patients of mean age 61 years ( range 34 85 years ) . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
The increase in plasma renin activity in response to a graded suprarenal aortic constriction was determined in conscious young ( 6 9 weeks of age ) and adult ( 14 16 weeks of age ) SHR and age matched Wistar Kyoto ( WKY ) control rats . ^^^ Under conditions of relatively little stress , the renin response to reduced renal perfusion pressure was not enhanced in young or adult SHR when compared with age matched WKY rats . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
Chronic monotherapy with calcium antagonists results in an antihypertensive response that is related directly to the patient ' s age and pretreatment blood pressure and indirectly to renin . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
In hypertensive patients , Bmax correlated positively with age ( r = 0 . 639 , p less than 0 . 05 ) and CD 25 ( r = 0 . 593 , p less than 0 . 05 ) and negatively with plasma renin activity ( r = 0 . 679 , p less than 0 . 05 ) , while in normotensive subjects , Bmax correlated with CD 25 only ( r = 0 . 615 , p less than 0 . 05 ) . ^^^ Thus , in patients with essential hypertension , a decrease in cardiac isoproterenol sensitivity and plasma renin activity is associated with an age related increase in antagonist binding capacity . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
In spite of the fact that plasma renin activity declines with age and drugs whose action is mediated via the renin angiotensin system might be expected to be less effective with increasing age , the limited available data suggest that both captopril and enalapril lower blood pressure in the elderly . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
At 60 weeks of age , rats that received perinatal low salt diet had significantly heavier adrenal glands when compared with the other groups , and the high potassium group had significantly elevated plasma renin concentrations . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
The antihypertensive effect was not related to age , pretreatment plasma renin activity , or serum ionized calcium concentration . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
The preoperative conditions of the patients ( age , duration of hypertension , plasma renin activity , plasma aldosterone concentration , and serum potassium concentration ) , postoperative sequential changes of hormone levels , and outcome of hypertension were compared among the groups in order to determine whether the differences of adrenal pathology would affect the postoperative course . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
Age as well as renin and black race help to design antihypertensive treatment strategies with better blood pressure control and better well being of the patient . . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
The blood pressure fall was correlated positively with age ( r = 0 . 521 ; p less than 0 . 001 ) and negatively with the rise in heart rate ( r = 0 . 308 ; p less than 0 . 01 ) and renin level ( r = 0 . 205 ; p = 0 . 05 ) . ^^^ After eliminating the linear effects of age by the partial correlation method , blood pressure fall and the initial renin level were no longer correlated ( r = 0 . 046 , NS ) , whereas the positive correlation between age and blood pressure fall persisted after eliminating the effect of renin ( r = 0 . 464 ; p less than 0 . 001 ) . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
Both groups did not differ in age , body weight and height , blood pressure , heart rate , plasma catecholamine levels , plasma renin activity ( PRA ) , and lymphocyte beta 2 adrenoceptor density . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
The characteristics of norepinephrine and epinephrine as well as plasma renin activity , angiotensin 2 , aldosterone , vasopressin , and atrial natriuretic factor ( ANF ) were examined in 64 patients ( mean age of 52 + / 16 years ) with dilated cardiomyopathy . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
Responsiveness appears to be related , as well , to pretreatment plasma renin activity and age . ^^^ Thus , the antihypertensive effect is directly related to age and inversely related to plasma renin activity . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
Isoproterenol ( ISO ; 10 ( 8 ) 10 ( 5 ) M ) significantly increased active renin secretion in all age groups ( P less than 0 . 05 ) , with newborns having the highest values at all concentrations . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
Of the 20 patients who had neither had renal surgery nor had end stage renal disease , all had a significantly lower glomerular filtration rate and renal plasma flow and higher diastolic blood pressure , mean arterial blood pressure , plasma renin activity , and serum beta 2 microglobulin concentration than 13 healthy age matched controls . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
The study concerned 8 pts , mean age 55 . 6 + / 7 . 7 years , 1 pt with aldosterone producing adenoma ( APA ) and 7 pts with idiopathic aldosteronism : plasma renin activity ( PRA ) and plasma aldosterone concentration ( PAC ) were respectively 0 . 30 + / 0 . 2 ng / ml / h ) and 314 + / 109 pg / ml . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
Plasma renin activity , active renin concentration and plasma aldosterone concentration were significantly and negatively correlated with age , but not with urinary sodium excretion . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
To evaluate the correlations occurring among plasma atrial natriuretic factor ( ANF ) , renin activity ( PRA ) , aldosterone ( ALD ) and urinary kallikrein ( KK ) in young hypertensives and in young normotensives with or without a family history of hypertension , 26 essential hypertensives ( mean age : 22 . 5 + / 2 ) , 21 normotensives ( mean age : 22 . 3 + / 1 . 9 ) and 13 normotensives with hypertensive heredity ( mean age 22 + / 1 . 8 ) under normal Na+ intake ( 120 mEq / daily ) were studied . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
Neither the acute nor long term responsiveness to doxazosin was related to age , plasma renin activity , plasma noradrenaline or the pretreatment sensitivity to phenylephrine . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
We measured plasma and extracellular fluid volume ( 125I albumin , 51Cr EDTA ) , plasma concentrations of renin , angiotensin 1 and 2 , aldosterone and atrial natriuretic peptide by radio immunoassays in insulin dependent diabetic ( IDDM ) patients with ( n=28 ) and without ( n=11 ) nephropathy and in 14 normal control subjects matched for sex and age . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
Similarly the low renin levels associated with increasing age and with elderly hypertensive patients , may be the result of the elevation of plasma ANP that occurs with aging . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
Plasma atrial natriuretic factor ( ANF ) , blood pressure , age , plasma renin activity and creatinine were measured in 50 normal volunteers , 141 essential hypertensives , 35 patients with chronic renal failure who had never been dialysed and 27 patients with end stage renal failure on constant haemodialysis . ^^^ Plasma ANF was correlated positively with age in the normal group ( r = 0 . 52 , P less than 0 . 01 ) and with blood pressure in the essential hypertensives ( r = 0 . 50 , P less than 0 . 001 ) , and negatively with renin in the normal and end stage renal failure patients ( r = 0 . 47 , r = 0 . 34 ; P less than 0 . 01 , P less than 0 . 05 , respectively ) . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
The antihypertensive efficacy both of angiotensin converting enzyme ( ACE ) inhibitors and thiazide diuretics has been claimed to be influenced by plasma renin activity , which declines with age and is low in blacks . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
Eighteen primary hypertensives ( 12 male , 6 female , mean age 57 . 7 + / 2 . 7 ) were entered in a placebo controlled , double blind crossover study of the effects of equipotent doses of pindolol and propranolol on mean + / SEM systolic BP , diastolic BP , heart rate , active renin ( AR ) , total renin ( TR ) , inactive renin ( IR ) , and % AR / TR . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
Hematocrit , red blood cell mass , plasma volume and plasma renin activity were evaluated in 33 ( 15 women ) young patients with borderline hypertension and in 30 ( 15 women ) age and sex matched normotensive control subjects . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
These results indicate that the total renin content of the plasma does not change , whereas the active renin content decreases with age in normal subjects , and suggest that activation of prorenin to active renin may be impaired in elderly subjects . . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
Although the elderly tend to have low plasma renin levels , the fall in blood pressure after ACE inhibitors is at least as great ( and in several studies greater ) than in younger age groups . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
Of twenty five subjects with high renin essential hypertension ( ten females , 15 males , mean age 30 years ) , 14 were noted to have a decrease in mean arterial blood pressure ( MAP ) when sodium intake was increased from 10 to 100 mmol / d . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
Circulating norepinephrine increased with aging , but a clear cut age related effect was not observed for renin system activity or sodium status . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
Age related changes in glomerular binding of ANG 2 in SHR were not found to be related to changes in either plasma renin activity or systolic blood pressure . . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
However , when blood pressure responders were compared with non responders within the same treatment group , plasma renin activity and PGE 2 excretion rates were higher in the responder group corresponding with younger age in both treatments . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
To evaluate the activity of sympathetic system and of plasm renin in elderly patients with borderline ( BH ) and established essential hypertension ( EH ) , 31 BH mean age 38 years and 30 EH , mean age 39 years ; 15 BH , mean age 66 years , and 15 EH , mean age 68 years , were studied at rest and after dynamic exercise . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
The cardiovascular and endocrine profile of cromakalim has been studied in 8 healthy men ( age 25 + / 2 years : means SEM ) and its influence on renin release from cultured rat juxtaglomerular cells in vitro has also been examined . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
Experiments were performed to determine the effect of veratridine , a substance known to promote norepinephrine release from nerve terminals , on active and inactive renin secretion from renal cortical slices of fetal ( 134 138 days gestation ; term is 145 days ) , newborn ( 4 9 days of age ) , and adult nonpregnant sheep . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
Neither age nor plasma renin activity independently influenced the response to calcium antagonists . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
Our study ; ( 1 ) reports concentrations for active and inactive renin determined by the immunoradiometric assay in normal infants and children ; ( 2 ) confirms , by use of the immunoradiometric assay , the previously described decrease in plasma active and inactive renin , as measured by the enzymatic assay , with increasing age ; and ( 3 ) shows close correlations between the results obtained by immunoradiometric and enzymatic assays for active and inactive renin in normal infants and children . . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
Renin messenger RNA ( mRNA ) levels were compared in the kidneys , livers , brains , adrenals , aortae and hearts of spontaneously hypertensive ( SHR ) and Wistar Kyoto ( WKY ) rats at 5 and 12 weeks of age using a ribonuclease protection technique . 2 . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
Plasma and urine norepinephrine , epinephrine , plasma renin activity and aldosterone were measured in 11 young men ( mean age , 21 years ) with a high blood pressure in the clinic who maintained a high home blood pressure and 12 men with an elevated clinic blood pressure who had a normal home blood pressure . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
This finding , together with the high renin and aldosterone values , indicated a nephrogenic hypertension causing both the cardiomyopathy found at 12 months of age and the endocranial hemorrhage . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
Weanling and young spontaneously hypertensive rats ( SHRs ) demonstrate higher plasma renin activity and plasma aldosterone concentration than age matched normotensive Wistar Kyoto ( WKY ) control rats . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
Based on prevailing hypotheses about the role of renin in essential hypertension , both Laragh and Buhler independently predicted that angiotensin converting enzyme ( ACE ) inhibitors would become less effective with increasing age , as elderly hypertensive patients tend to have low plasma renin activity . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
The groups did not differ with regard to blood pressure and heart rate , age , body weight and height , plasma renin activity and catecholamines , and serum electrolytes and creatinine . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
It is suggested that the sensitivity of the neural control of renin release as well as the arterial baroreflex sensitivity are influenced by age , and possibly the inflexibility of the vascular system . . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
In the untreated patients with essential hypertension ( n = 55 ) , converting enzyme activity was inversely related to mean arterial pressure and age ( r = 0 . 34 , p less than 0 . 01 ) and positively related to plasma renin activity ( r = 0 . 31 , p less than 0 . 05 ) . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
These agents may differ in the relation between the magnitude of their antihypertensive effect and patients ' pretreatment plasma renin activity and age . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
The patient ' s age , gender , race , behavior profile , hemodynamic and neurohumoral status ( plasma renin activity , norepinephrine / epinephrine ratio ) , and quality of life will help determine the choice of antihypertensive agent . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
Antihypertensive treatment according to age , plasma renin and race . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
SBP , heart weight / body weight ratio and plasma renin activity remained unchanged at 39 weeks of age . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
Twelve hypertensive patients ( mean age 46 . 6 years , range 37 55 years ) with fibromuscular dysplasia of the renal artery were treated with percutaneous transluminal renal angioplasty ( PTRA ) and the effects on the renin angiotensin aldosterone system and blood pressure were studied in the acute phase . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
Age , race , blood pressure and renin : predictors for antihypertensive treatment with calcium antagonists . ^^^ Age , race , pretreatment blood pressure and plasma renin activity have been related to the antihypertensive response to calcium antagonists in studies that included 215 patients with mild to moderate essential hypertension . ^^^ In a multiple linear regression analysis of 138 white patients , age , pretreatment blood pressure and renin activity were of independent and significant predictive value for the antihypertensive response . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
Mean arterial pressure changes were inversely correlated with basal renin levels and directly associated with age . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
Atrial natriuretic peptide in hepatic cirrhosis : relation to stage of disease , sympathoadrenal system and renin aldosterone axis . 58 patients ( mean age 51 years ) with cirrhosis of the liver were studied . 16 patients were compensated , 18 decompensated with ascites , and 24 decompensated and treated with diuretics . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
Age , duration of hypertension and renal vein renin ratio seem to be important prognostic factors for the outcome of surgery or PTRA . . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
Combining these data with developmental patterns of plasma renin activity in S / JR rats suggests the possibility that the S / JR rat may become intravascularly volume expanded between 25 and 51 days of age . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
There were no significant differences among the three groups in age , serum protein , albumin , or electrolyte levels , plasma renin activity ( PRA ) , or plasma concentrations of aldosterone and cortisol . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
To assess the role of atrial natriuretic peptide ( ANP ) in relation to the sympathoadrenal and renin angiotensin aldosterone system , and sodium excretion , 88 cirrhotic patients ( mean age 52 years ; 28 compensated , 28 decompensated with ascites , and 32 decompensated and treated with diuretics ) and 26 control subjects were investigated . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
There were no differences between patients with normal hANP levels and patients with hANP levels above normal range regarding age , diabetes duration , metabolic control , kidney function ( creatinine clearance and proteinuria ) , electrolytes , and in plasma renin activity , aldosterone , epinephrine and norepinephrine levels in plasma . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
This study details the efficacy of fosenopril at rest and during exercise on blood pressure , plasma potassium , plasma renin activity , and plasma aldosterone in 11 hypertensive males , mean age 55 years . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
Cure or improvement was noted more often in patients with fibromuscular dysplasia , short history of hypertension , pathologic renin quotient , normal total hippuric acid clearance , or age under 40 years . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NT and EH groups were similar with respect to age and basal levels of renin , aldosterone and ANP ( 34 . 5 + / 5 . 5 in NT and 32 . 5 + / 6 . 3 pg / ml in EH , mean + / sem ) . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
NT and HT groups were similar with respect to age and basal levels of renin , aldosterone and ANP ( 34 . 5 + / 5 . 5 in NT and 32 . 5 + / 6 . 3 pg / ml in HT , mean + / SE ) . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
Atrial natriuretic factor , digoxin like immunoreactive substance , and plasma renin activity were unrelated to umbilical vessel source or gestational age . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
The relationship between plasma atrial natriuretic factor ( ANF ) , blood pressure ( BP ) , age , plasma renin activity ( PRA ) and urinary sodium excretion was studied in 64 normal subjects ( mean age 48 . 7 + / 2 . 1 yrs ; BP : 126 . 5 + / 1 . 6 / 79 . 5 + / 0 . 9 mmHg ) and in 104 untreated uncomplicated essential hypertensives ( 50 . 8 + / 1 . 1 yrs ; BP : 164 . 7 + / 1 . 6 / 105 . 2 + / 0 . 6 mmHg ) . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
These characteristics include age , sex , race , therapy , stage of hypertension , sodium intake , renal function , and renin status . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
The decrease in blood pressure with calcium antagonists was directly correlated with the patient ' s age and inversely with the pretreatment plasma renin activity . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
The plasma potassium reduction could not be predicted by age , plasma renin activity , plasma and urinary aldosterone or urinary kallikrein . ( ABSTRACT TRUNCATED AT 250 WORDS ) . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
In a study of 38 fetuses total kidney renin was significantly correlated with gestational age ( r = 0 . 63 ) . ^^^ Although whole fetal kidney renin specific activity was found to decrease with gestational age ( r = 0 . 65 ) , the mean value of the specific activity was about 20 times greater than in normal adult cortex and double that in tissue from patients with renal artery stenosis , suggesting renin angiotensin system hyperactivity . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
The age related changes in the renin angiotensin system were investigated in normotensive 3 , 10 , 20 , and 30 mo old female Wistar rats . ^^^ Plasma renin concentration and immunofluorescent renal renin index remained constant from 3 to 10 mo , then decreased as the animals become older , whereas plasma concentration of renin substrate diminished slightly between 10 and 20 mo and plasma converting enzyme activity was not modified with age . ^^^ These results indicate that the activity of the renin angiotensin system is progressively reduced with age and suggest that angiotensin 2 does not play an important role in the maintenance of blood pressure and kidney hemodynamics in normotensive female senescent rats . . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
The pharmacokinetics of ramipril , a new potent long acting non sulphydryl converting enzyme inhibitor , and its effects on blood pressure , plasma renin activity and angiotensin 2 concentrations were studied in a group of 8 elderly volunteers ( mean age 77 , range 61 to 84 ) . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
Changes in arterial pressure were unrelated to age , plasma ionized calcium , parathyroid hormone ( PTH ) , plasma renin activity ( PRA ) , plasma aldosterone , 24 h urinary calcium , sodium and potassium and were only weakly related to body weight . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
Possible factors influencing response include drug dose , plasma drug concentration , plasma renin activity , baseline blood pressure , nonionized calcium in blood and inside vascular smooth muscle cells , patient age and patient race . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
We studied 108 subjects ( age range , 4 to 76 years ) to determine the effect of age on prorenin ( inactive renin ) , active renin , and plasma renin activity in normal children , adolescents , and adults . ^^^ Prorenin concentrations were positively correlated with age over the range of 4 to 76 years , while plasma renin activity and active renin concentration were negatively correlated with age . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
The current investigation was performed to determine whether there are changes in the renin angiotensin system with increasing age in rats . ^^^ There were no changes in plasma renin activity or angiotensin 2 concentrations , but the number of angiotensin 2 binding sites in isolated glomeruli increased with increasing age ( r = 0 . 87 , P less than 0 . 01 ) . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
The effects of dietary sodium upon serum and urinary calcium and selected vitamin D metabolites were studied in two groups ( n = 10 each ) of age and gender matched , white normotensive subjects and patients with normal renin hypertension . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
Glomerular filtration rate , renal plasma flow , active renin , renin substrate and angiotensin 2 concentrations were monitored in nine consecutive patients ( 3 women , 6 men , mean age 31 years ) with newly diagnosed , insulin dependent diabetes . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
To evaluate the activity of the sympathetic system and of plasma renin in elderly patients with borderline and established essential hypertension , 31 borderline hypertensives aged less than 60 years ( mean age 38 years ) , 30 established essential hypertensives aged less than 60 years ( mean age 39 years ) , 15 borderline hypertensives aged greater than 60 years ( mean age 66 years ) and 15 essential hypertensives aged greater than 60 years ( mean age 68 years ) were studied at rest and after dynamic exercise . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
Vol . 21 , pp . 63 75 ) we showed that thirst elicited by activation of the brain ' s renin angiotensin system in the suckling becomes specific to water after 16 days of age . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
In a cross sectional analysis , plasma renin activity , renin concentration and aldosterone concentration showed no relationship with age . ^^^ From these cross sectional and longitudinal observations we conclude that beyond the age of 60 ageing has no detectable effect on plasma renin and aldosterone levels in these elderly hypertensive patients . . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
The arterial blood pressure ( BP ) , the ratio between gram myocardial mass per 100 g body mass ( R ) , the plasma renin activity ( PRA ) and the aldosteron content in the blood plasma ( PA ) were investigated in a model of renal hypertension , 30 days after the operation , in the following groups of male Wistar rats : operated and treated throughout the entire experimental period with captopril Pharmachim in a dose of 30 mg / kg body mass twice daily orally , and two control groups operated and treated with saline , and non operated animals of the same age , treated only with saline . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
No significant difference between these two groups was observed with respect to systolic pressure , age , sex , plasma potassium , plasma renin activity and plasma aldosterone levels . ( ABSTRACT TRUNCATED AT 250 WORDS ) . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
The captopril treated rats had a significant elevation in serum renin activity at 12 weeks of age indicating the presence of chronic converting enzyme inhibition , and the 6 OHDA treatment resulted in a depletion of hypothalamic ( 86 % ) and brainstem ( 76 % ) norepinephrine content . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
Plasma renin activity ( PRA ) , aldosterone ( aldo ) levels , electrolyte levels , and blood pressures were measured in 16 patients with affective disorders taking lithium prophylactically , and in 16 age and sex matched control subjects . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
When plasma renin activity is measured in the infant with renal failure of hypertension , one must compare the result with the normal range of values related to postnatal age of normal infants . . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
Significant reductions in kinin excretion were noted in the patients with liver disease which could not be accounted for by differences in age , plasma renin , aldosterone excretion or sodium excretion . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
This antihypertensive effect was related directly to the height of pretreatment arterial pressure ( r = 0 . 67 , p = 0 . 006 ) but not to age or pretreatment plasma renin activity . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
Plasma renin activity was measured at 11 and 16 weeks of age . 2 . ^^^ Plasma renin activity was negatively correlated with both glomerular filtration rate and renal blood flow , but the relationship was stronger at 11 than at 16 weeks of age . 3 . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
Beginning at 3 5 days of age , renin increased ingestion of milk and water off dam . ^^^ After 15 days of age , milk ingestion off dam was no longer increased by renin , but intake of water continued to be evoked . ^^^ In contrast , renin did not increase intake by suckling at any age . ^^^ These findings reveal that the adult characteristics of the dipsogenic action of the renin angiotensin system in the brain emerge at 15 days , at which age the increased intake becomes entirely specific for water . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
The N induced changes in supine systolic and diastolic pressure correlated ( p less than 0 . 05 ) with age ( r = 0 . 65 and r = 0 . 58 , respectively ) and pretreatment plasma renin activity ( r = 0 . 71 ) . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
Glandular renin levels are higher in the neonatal period than at 2 3 weeks of age , and then rise dramatically with the onset of puberty . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
Chronically catheterized fetal lambs ( n = 11 , gestational age 111 139 days ) and neonatal lambs ( n = 20 , postnatal age 4 30 days ) were studied to explore during development the relationship of renal hemodynamic responses during hypoxemia to plasma epinephrine concentration ( E ) , plasma norepinephrine concentration ( NE ) , plasma arginine vasopressin concentration ( AVP ) , and plasma renin activity ( PRA ) . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
Blood pressure , both venous and urinary catecholamines and plasma renin activity ( PRA ) were studied in 10 patients ( 6 men and 4 women , mean age 70 + / 10 years ) on the first three days after cerebral infarction . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
These results suggest that a considerable relationship exists between intracellular sodium and free calcium in lymphocytes and that , in essential hypertension , the alteration in cellular metabolism of sodium and calcium may be linked to the renin system but not to blood pressure , age , or adrenergic activity . . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
Blood pressure , plasma renin activity and the concentrations of aldosterone and cholesterol in plasma and sodium and potassium in urine ( 48 h collections ) and nutrient intakes were determined in 22 vegans ( 11 male and 11 female ) and omnivore controls matched for age , sex and body build . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
Renin administered into the preoptic area at 105 days of age caused an increase in salt intake , but the increase was markedly inhibited by the oral administration of taurine as well . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
Statistically significant changes were found in plasma renin activity ( P less than . 001 ) and plasma aldosterone ( P less than . 001 ) when the hypertensive patients were divided into two age groups , those under 45 and those over 45 . ^^^ These changes were not found in the normal subjects in the same age groups , indicating that age is an important influence on the renin aldosterone system in hypertensive patients , and leads to variations in this hormonal axis similar to those observed in normal elderly subjects . . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
Further difficulties in comparing one trial with another include differences with respect to age , race , severity of hypertension and renin status in the patient populations under investigation , since all these factors may influence responsiveness to therapy with both classes of agent . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
Chronic monotherapy with a calcium antagonist results in an antihypertensive response , which is directly related to the patient ' s age and pretreatment BP and indirectly related to plasma renin levels . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
Plasma renin activity was inversely correlated with age , but was not related to the reduction of SBP or DBP . ( ABSTRACT TRUNCATED AT 250 WORDS ) . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
Furthermore , when the activity of the plasma renin system decreases with advancing age , increased activity of a local angiotensin system may contribute to the regulation of vascular tone . . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
The ratios did not correlate with patient age or plasma renin level . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
Effect of age on the renin angiotensin aldosterone system in normal subjects : simultaneous measurement of active and inactive renin , renin substrate , and aldosterone in plasma . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
These groups could not be distinguished on the basis of sex , age , or pretreatment plasma renin activity . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
Serum renin activity ( SRA ) also increased in both strains receiving PEG at 6 and 8 wk of age , but the response was suppressed in the SHR relative to the WKY ( P less than 0 . 001 ) . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
To clarify age related changes in the plasma renin activity ( PRA ) aldosterone ( ALDO ) system in relation to urinary sodium ( Na ) excretion in pseudohypoaldosteronism type 1 ( PHA ) , we followed a patient with PHA serially by measuring the hormonal balance and urinary electrolyte excretion for 5 years . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
Blood pressure tended to be higher in the former ( 121 / 78 + / 9 / 8 ( s . d . ) versus 113 / 74 + / 11 / 9 mmHg ; P less than 0 . 005 ) ; mean age , urinary sodium or potassium excretion , plasma sodium , potassium , renin activity or aldosterone levels and creatinine clearance were comparable . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
The two study groups had a similar mean age ( 24 + / 2 ( SD ) yr ) , body weight , blood pressure ( 112 / 64 + / 10 / 7 mmHg ) , heart rate , plasma and urinary sodium and potassium , and plasma norepinephrine , epinephrine , angiotensin 2 , renin and aldosterone levels . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
Blood pressure , pulse rate ( PR ) , serum osmolality and electrolytes , as well as plasma vasopressin ( PVP ) and plasma renin activity ( PRA ) , were measured in five men and two women [ mean age 38 . 6 + / 3 . 9 ( SE ) yr ] before , during , and after inflation of an antigravity suit that covered the legs and abdomen . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
To clarify the pathogenesis of this hypertension we examined the blood pressure ( BP ) behaviour and the renin angiotensin aldosterone system in 31 TS patients ( 2 22 years of age ) . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
Plasma renin activity rose significantly in all cases whereas plasma aldosterone dropped and reached normal levels for age . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
Evaluation of an aldosterone radioimmunoassay : the renin angiotensin aldosterone axis as a function of sex and age . ^^^ Measurement of plasma aldosterone and plasma renin activity in these subjects showed that both these parameters are higher in subjects under 40 years of age than in those over 40 . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
Multiple regression analysis revealed that urinary potassium excretion was influenced by age , race , sex , body weight , blood pressure , creatinine clearance , renin , and aldosterone . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
We report a patient who presented in 1974 at age 15 yr with blood pressure of 240 / 120 mm Hg , serum K of 3 . 1 mM , low renin , and high normal aldosterone excretion , with findings diagnostic of GSH . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
Adrenal ZG renin was significantly decreased in S as compared with R rats even at 6 weeks of age , when both S and R rats are still normotensive ( S = 7 . 2 + / 0 . 2 , R = 18 . 0 + / 1 . 6 ng angiotensin I / mg protein / hr ) . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
To investigate this possibility we measured plasma renin activity ( PRA ) in 23 patients ( 17 male , 6 female , age 41 70 ) with New York Heart Association stage 3 heart failure due to ischaemic heart disease in a placebo controlled trial over one month . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
Age and renin status do not reliably predict sodium sensitivity . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
Renin relationship to sex , race and age in a normotensive population . ^^^ The relationship of renin activity to sex , race ( black or white ) and age ( less than 50 or greater than or equal to 50 years of age ) was examined in 236 normal subjects measure yearly for up to 9 years . ^^^ However , the sex and race differences primarily occurred as a consequence of a lack of decline in renin activity with age among white men . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
Plasma renin activity was lower in 13 mothers with small for gestational age ( SGA ) infants ( 5 . 2 + / 0 . 89 ng / ml per h , compared with 13 mothers with appropriate for gestational age ( AGA ) infants ( 16 . 65 + / 2 . 37 ng / ml per h , P less than 0 . 001 . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
There were no significant differences between the 3 groups with respect to age , ideal body weight , supine resting mean blood pressure , serum creatinine , daily urinary excretion of sodium , or renin substrate at the time of study . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
The values for plasma renin substrate concentration are similar to those reported for younger age groups . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
Plasma renin activity decreased with age in NC but remained elevated in LC . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
The prognosis of hypertension was evaluated pre operatively in 40 patients with primary aldosteronism owing to adenoma by examining the severity of hypertension , family history of hypertension , age of the patients , duration of hypertension , plasma renin activity , plasma aldosterone concentration , and efficacy of spironolactone ( 100 mg per day for 10 days ) on blood pressure . ^^^ There were no significant differences in the age of the patients , family history of hypertension , plasma renin activity or plasma aldosterone concentration between these two groups . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
The predictive value of the duration of arterial hypertension , patient ' s age , plasma renin activity coefficient and quantitative intrarenal flow data obtained at angiography with a simultaneous droperidol test , was determined . ^^^ Predictive use of other parameters , such as the duration of arterial hypertension , patient ' s age , plasma renin activity coefficient yielded higher rates of false positive and false negative results . . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
The Ren vascular bed showed no consistent response in both age groups . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
A newly standardized projective test of reactions to frustration , a questionnaire related to such characteristics as aggressiveness and dominance , and a standardized interview were applied to 16 patients with established high renin essential hypertension and 21 patients of similar age with normal renin . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
In the controls , the level of plasma inactive renin increased slightly with age but was never above 50 ng per milliliter per hour . ^^^ In young diabetic patients studied within three years of the onset of diabetes the concentration of inactive renin was normal , and in some older diabetics without complications it remained within the age adjusted normal range for many years . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
The relationships between arterial pressure ( BP ) and plasma vasopressin levels , plasma renin activity , and other variables were determined in 96 untreated essential hypertensive men ( 146 / 100 mm Hg ) and women ( 153 / 102 mm Hg ) whose average age was 44 years , 80 normal men and women ( 121 / 79 mm Hg ; mean age , 47 + / 2 years ) , and 40 subjects defined as borderline hypertensive . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
Thus , age is a variable with a substantial effect on plasma concentrations of vasopressin in addition to the well known effect on renin and noradrenaline . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
The rise in renin was inversely related to age . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
Sodium and renin profiles based on race and age ] . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
Changes in reactivity of the renin angiotensin aldosterone system in old age as a risk factor in the development of hypertension ] . ^^^ The sensitivity of the renin angiotensin aldosterone system ( RAAS ) to regulatory sympathoadrenal and hypothalamo pituitary effects was shown to increase with advancing age , in spite of declining plasma renin and aldosterone baselines . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
Plasma renin activity ( PRA ) and systemic and forearm hemodynamics were studied during acute changes in cardiopulmonary blood volume and central venous pressure in 20 subjects , including 9 normotensive controls and 11 essential hypertensive patients of the same age . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
We studied plasma renin activity and concentration , and factors involved in their control ( age , blood pressure , and sodium excretion ) in 40 healthy subjects ( group 1 ) , 18 patients with type 1 diabetes without complications ( group 2 ) , and 31 with type 1 diabetes with proliferative retinopathy ( group 3 ) . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
Moreover , the possible interrelationships between urinary kallikrein excretion and age , sex , electrolyte excretion , and plasma renin activity were examined . ^^^ In these patients the enzyme was weakly and positively related to urinary potassium and plasma renin activity ; no correlation was found with blood pressure , urinary sodium , age , or sex . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
Circadian rhythms of plasma renin activity and aldosterone : changes related to age , sex , recumbency and sodium restriction . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
Differences in renin and aldosterone could not be explained by age , natriuresis or plasma volume . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
The pattern of response to postural changes of blood pressure ( BP ) , plasma renin activity ( PRA ) and plasma aldosterone concentration ( PAC ) was investigated in 11 patients with renal mobility and without treatment and compared with that of an age and sex matched group of untreated hypertensives without renal mobility . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
Influence of age and sex and of castration on renin substrate of normal and nephrectomized rats . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
Relation of age , diastolic pressure and known duration of hypertension to presence of low renin essential hypertension . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
The antihypertensive efficacy of the calcium entry blocker nitrendipine administered as monotherapy ( 20 80 mg ; mean , 36 / day ) on the average for 144 days to 46 patients with essential hypertension ( WHO 1 and 2 ) was investigated in relation to age , pretreatment blood pressure , and plasma renin activity . ^^^ The fall in mean blood pressure after nitrendipine was directly related to age ( r = 0 . 553 ; p less than 0 . 001 ) and pretreatment mean blood pressure ( r = 0 . 470 ; p less than 0 . 01 ) and inversely related to plasma renin activity ( r = 0 . 558 ; p less than 0 . 001 ) . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
Age dependence of the response of blood pressure , heart rate and plasma renin activity to captopril in essential hypertension ] . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
P . ) , pulse rate , several hormones [ plasma renin activity ( PRA ) , plasma aldosterone ( PA ) , ACTH , plasma cortisol ( PC ) , urinary catecholamines and urinary aldosterone ] and urinary electrolytes were investigated in 9 male patients with essential hypertension [ mean age 36 . 2 + / 4 . 1 ( S . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
A 19 year old female , known to have had hypertension and hypokalemic alkalosis since the age of 9 months , was found to have suppressed renin , negligible plasma and urinary aldosterone and low plasma levels of other known sodium retaining steroids . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
Effect of age on diagnostic usefulness of stimulated plasma renin activity and saralasin test in detection of renovascular hypertension . ^^^ The diagnostic usefulness of the timed intravenous pyelogram ( IVP ) , isotopic renal flow study ( renal flow ) , stimulated plasma renin activity ( SPRA ) , saralasin infusion test , and renal vein renins ( RVR ) in detecting possible renal vascular hypertension was studied in relation to age . ^^^ The results indicate an increasing usefulness with age of a high SPRA or a positive saralasin test in indicating an abnormal renal 10 ray and an abnormal renal vein renin ratio , and thus a potentially correctable lesion . . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
Role of renin profile and age in the choice of the therapeutic approach of arterial hypertension ( author ' s transl ) ] . ^^^ In conclusion our data indicate that age must be taken into account in classifying hypertensive patients in renin subgroups . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
Renin measurements serve as an endocrine marker for the activity and reactivity of the sympathetic nervous system reflecting a beta adrenoceptor mediated response which tends to decrease with older age . ^^^ As lower renin and as older the age diuretic agents and calcium antagonists are more effective , the hyporesponsive renin being a co determinant of pressure response in these patients . . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
Patients with a high renin value and usually younger age respond better to drugs that interfere with the renin angiotensin system , that is , beta blockers or converting enzyme inhibitors . ^^^ Patients with a low renin value and often older age respond better to calcium entry blockers or diuretics . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
The antihypertensive effects of the calcium antagonists were directly related to the patient ' s age , pretreatment blood pressure but indirectly to pretreatment renin . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
Renin was not detected in any cell at any age . . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
The antihypertensive efficacy of the calcium antagonist verapamil was tested in 43 patients with essential hypertension , examining relationships between age and pretreatment renin and blood pressure and comparing intraindividually the responses with those obtained using beta blockers ( n = 29 ) and diuretic therapy ( n = 18 ) . ^^^ Verapamil produced a decrease in mean blood pressure that was directly related to the patient ' s age and pretreatment blood pressure but inversely to pretreatment renin . ^^^ Although there was no difference in overall pressure response between verapamil , beta blocker , and diuretic therapy , the pressure responses with diuretics paralleled those obtained with verapamil , whereas , in contrast , responses with beta blockers correlated indirectly with the patient ' s age and directly with pretreatment renin . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
Blood pressure , exchangeable sodium content , sodium metabolic balance , and plasma concentrations of active renin , angiotensin 2 , and aldosterone were measured in seven normal men and 10 essential hypertensive men of similar age and weight . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
No correlation was found between pump inhibition and age , sex , blood pressure , levels of plasma K+ or Na+ , or plasma renin activity . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
In future studies on hypertensive humans we should pay more attention to the characteristics of the patients ( sex , race , age , drug therapy , stage of hypertension , sodium intake , renal function , and renin status ) and make a more vigorous effort to match these patients properly with normotensive control subjects . . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
No significant difference was found between the latter two groups in regard to age , sex , weight , etiology of hypertension , pretreatment ECG voltage , blood pressure , plasma renin activity , duration of treatment and duration of maintained blood pressure control . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
Plasma renin activity , 11 deoxycorticosterone , corticosterone and aldosterone levels were all increased several fold over the normal range for age , thus excluding an adrenal biosynthetic defect . ^^^ However at 3 1 / 2 years of age , plasma renin activity and aldosterone were still markedly elevated while precursor steroids were normal and the clinical condition satisfactory . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
The purpose of this investigation was to correlate the development of the various enzyme activities associated with the renin angiotensin system with age related differences in the steady state concentrations of angiotensin 1 ( AI ) and 2 ( AII ) . ^^^ Plasma renin activity and concentration increased between birth and 3 wk of age , and declined thereafter to adult values . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
An inverse relationship between plasma renin , aldosterone and age has been demonstrated . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
In hypertensives this age dependent beta receptor related effect tends to be enhanced as judged from the greater reduction of cardiac isoproterenol sensitivity and the blunted renin response to exercise stimulation . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
The ability of plasma to stimulate G6PD was inversely correlated with plasma renin activity in the hypertensive patients and increased with age and sodium intake in the normotensive subjects . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
Plasma renin activity was significantly elevated ( p less than 0 . 001 ) at 48 72 h and urinary epinephrine levels were significantly lower ( p less than 0 . 05 ) at 24 48 h of age in the drug group , and norepinephrine levels were equivalent . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
Renin was present in all brain regions studied and decreased with the age of the animals . ^^^ An increased activity of renin was measured in several nuclei of the brain stem and in the neurohypophysis of young hypertensive rats when compared with age matched normotensive control animals . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
The renin angiotensin system was examined in Fischer rats at 7 , 11 and 14 days after Leydig cell tumour transplantation , and in age matched controls . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
Changes in renal plasma flow correlated inversely with age and final mean arterial pressure and correlated positively with initial plasma renin activity of subjects . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
Recent findings concerning tonin , a serine protease , are described : a ) 80 % of its amino acid sequence , b ) its different characteristics from other serine proteases , from renin , cathepsin D and the angiotensin 1 converting enzyme , c ) the activation of inactive renin , d ) its involvement in the 1K 1C hypertensive rats , e ) the demonstration of its presence in the distal tubular cells of the rat kidney , and finally , f ) its presence in urine and the influence of age and of sodium intake on its urinary excretion . . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
There was no significant difference between the two groups as regards age , preoperative BP level , plasma renin activity , blood volume , or response to [ Sar 1 , Thr 8 ] A 2 . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
In 40 male patients with essential hypertension less than the age of 36 years , the plasma prolactin ( PRL ) , plasma renin activity ( PRA ) and plasma catecholamines ( noradrenaline ( NA ) and adrenaline ( A ) ) were determined simultaneously . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
Plasma renin concentration ( PRC ) , activity ( PRA ) and substrate concentration ( PRSC ) were measured in 27 males and 31 female children aged 3 days to 14 . 5 years ( median age 10 months ) . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
Relationship with age and plasma renin activity . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
Relationships between age , pretreatment blood pressure , pretreatment plasma renin activity , and hypotensive response were examined . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
In order to observe alterations of the Renin Angiotensin Aldosterone ( RAA ) system in elderly individuals , 40 healthy Venezuelan mestizos ( 8 men , 32 women ) over 60 years of age were examined . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
Central and forearm arterial and venous hemodynamics , arterial baroreflex sensitivity , plasma renin activity , and catecholamines were studied in supine position and after 10 degrees head down tilt in 29 patients with sustained essential hypertension and in 29 normotensive controls of the same age and sex . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
Plasma aldosterone concentration was markedly elevated , and plasma renin activity was similar to or higher than that reported in normal infants of comparable age . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
Multiple regression analysis showed that the addition of age and plasma renin activity made little effect . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
Superficial cortical and juxtamedullary glomeruli were obtained from animals at 1 , 2 , and 4 wk of age and from adults to determine renin concentration . ^^^ Superficial cortical glomerular renin concentration at 1 wk of age averaged 7 . 7 + / 1 . 6 ( S . ^^^ Total renal renin concentration increased with age and showed a significant positive correlation with the concomitant increase in kidney weight . ^^^ But renal renin content increased more than kidney weight between 1 2 wk of age . . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
Gestational age was inversely correlated with plasma ritodrine concentration , plasma renin activity , and urinary arginine vasopressin excretion . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
The influence of age on the activity of the renin angiotensin system in rats with adrenal regeneration hypertension . ^^^ The changes of plasma concentration of renin ( PRC ) , and its substrate ( RSC ) and renal renin activity ( RRA ) , considered as an indicator of the secretory activity of the regenerating adrenal were studied 5 , 10 , 20 , 40 and 60 days after the adrenal enucleation to look for possible age differences related to the higher susceptibility of immature rats to the hypertensive influence of the regenerating adrenal . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
Urinary excretion of kallikrein ( UKal ) , sodium , potassium , protein , and creatinine , as well as the kidney content of kallikrein and renin , was studied in spontaneously hypertensive FH / Wjd ( FH ) male and female rats and in age and sex matched normal Wistar rats . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
The effect of age on the renin angiotensin aldosterone systems and other physiological variables in normal subjects . ^^^ The influence of age on the renin angiotensin aldosterone ( RAA ) system in 125 normal subjects , ages ranging from 13 90 , in Valencia , Venezuela , was evaluated . ^^^ A highly significant inverse correlation was found between age and stimulated plasma renin activity ( r = 0 . 7149 , p less than 0 . 001 ) , and between age and urinary aldosterone ( r = 0 . 4837 , p less than 0 . 001 ) . ^^^ Plasma renin presented an appreciable percentage of decrease when compared to the highest levels found in the lowest age group ; plasma renin decreased 80 % , while urinary aldosterone decreased only 40 % between ages 80 and 90 . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
The hypotensive action of the angiotensin converting enzyme inhibitor captopril was investigated in 13 hypertensive patients in relation to their age , body weight , the pretreatment level of plasma renin activity ( PRA ) , serum creatinine concentration and suppression of angiotensin 2 ( PA 2 ) by captopril . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
Parameters such as age , sex , blood pressure , plasma renin activity , and plasma aldosterone concentration were also examined in 2 groups of essential hypertensive patients , divided on the basis of their Na+ / K+ net fluxes . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
Relationships between plasma catecholamines , renin , age and blood pressure in essential hypertension . ^^^ The aim of this study was to examine the interrelationships between age , plasma catecholamines , plasma renin activity ( PRA ) and blood pressure in essential hypertensive ( EH ) patients . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
The study also disclosed age specific changes of the renin activity in blood plasma and renal cortical tissue ; with age it tended to decline both in plasma and kidneys . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
The incidence of disorders in renin secretion is different in relation to sex , age and duration of hypertension . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
In normotensive pregnant women ( n = 26 ) there was a rise in all components of the RAAS measured : plasma renin activity ( PRA ) , plasma aldosterone concentration ( PAC ) and urinary aldosterone excretion ( tU Aldo ) , from week 12 to week 20 of pregnancy , compared with non pregnant control subjects ( n = 24 ) of similar age . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
Nyctohemeral values of plasma renin and aldosterone in relation to age , sex and sodium intake and posture ] . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
Possible factors involved in the control of plasma renin activity ( PRA ) and concentration ( PRC ) have been analysed in 49 patients with long standing Type 1 diabetes and in 40 healthy controls matched for age and sex . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
Plasma renin activity remained unchanged at 37 weeks of age though the treatment was effective . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
A significant ( P less than 0 . 001 ) age related decrease for active ( r = 0 . 60 ) , inactive ( r = 0 . 59 ) and total renin concentration ( r = 0 . 66 ) was observed . ^^^ After correction for the influence of age , active renin concentration correlated with plasma renin activity ( r = 0 . 81 ) , but not with inactive renin concentration ( r = 0 . 18 ) . ^^^ The proportions of active and inactive renin were not related to age , and the overall percentage of inactive renin was 79 % . . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
Infants with HA had extremely elevated plasma renin activity ( PRA ; 70 650 ng angiotensin 1 / ml 10 h ) , which gradually decreased with age , and PRA was normal in adults . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
In several clinical studies , the decrease in blood pressure following the administration of calcium channel entry blockers was directly correlated to the patient ' s age and pretreatment blood pressure , and indirectly to the pretreatment plasma renin activity . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
Relationships with age , blood pressure , exchangeable sodium , renin , aldosterone and catecholamines . ^^^ The two study groups did not differ in age , sodium and potassium metabolism , and plasma levels of renin , aldosterone and norepinephrine , while plasma epinephrine was slightly higher in essential hypertension . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
Interrelations between systemic arterial pressure , extracellular fluid ( ECF ) volume , exchangeable sodium ( Na ) and the renin angiotensin aldosterone system were studied in 38 young patients with borderline hypertension and in 37 age and sex matched control subjects . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
Basal and ambulant plasma renin activity ( PRA ) were measured in 12 insulin dependent diabetics ( IDDS ) with elevated glomerular filtration rate ( GFR ) , 12 IDDs with normal GFR matched for age , sex and duration of diabetes and 12 age and sex matched non diabetic control subjects . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
This study examines the influence of posture on plasma prolactin , plasma catecholamines , plasma renin activity , blood pressure and heart rate in 24 patients with borderline hypertension ( age 19 + / 1 years ) and 20 normotensive subjects matched for age and body mass index . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
Blood pressure , plethysmographically determined muscle blood flow in the calf at rest and during maximal dilatation , plasma renin activity , angiotensin 2 and plasma and urinary aldosterone were determined in normotensive men with a positive family history of hypertension ( n = 17 ) and in an age and weight matched control group ( n = 15 ) during usual sodium intake and after four weeks of increased salt intake . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
We conclude that the high renin levels at young age contribute to the basal arterial pressure in puppies . . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
Direct and indirect measurement of urinary kallikrein excretion in patients with essential hypertension and normotensives : relation to age and plasma renin and aldosterone levels . ^^^ The relevance of age and activity of the renin angiotensin aldosterone system to the excretion of urinary kallikrein ( Ukal ) was studied in twenty five patients with essential hypertension and forty normotensive controls . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
Awake blood pressure variability , age , resting plasma renin activity and resting plasma noradrenaline levels did not have a significant correlation with left ventricular mass index . 3 . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
Activation of the renin angiotensin system may in part be responsible for the abnormally increased vascular tone which occurs in heart failure ; it has also been suggested that this system ' s responsiveness may diminish with age . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
Antihypertensive responses correlated directly with pretreatment blood pressure ( p less than 0 . 001 ) and the patient ' s age ( p less than 0 . 01 ) , and indirectly with plasma renin activity ( p less than 0 . 01 ) . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
The present study was designed , therefore , to determine the effects of 6 oxo PGE 1 on blood pressure ( BP ) , the renin angiotensin aldosterone system and platelet aggregability in man . 6 healthy male volunteers ( mean age : 24 . 3 + / 1 . 2 years ) and one patient with Shy Drager syndrome ( a 57 year old female ) were studied . 6 oxo PGE 1 , dissolved in physiological saline , was infused intravenously at three different doses of 7 . 5 , 15 and 30 ng / kg / min , for 15 min each . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
Blood pressure , heart rate , plasma renin activity , adrenaline and noradrenaline concentrations , and plasma or urinary electrolyte estimations did not differ significantly between two groups of normotensive subjects matched for age and sex with and without a family history of hypertension . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
In a comparison of the age matched NT , normal renin EHT ( NRH ) and low renin EHT ( LRH ) , the mean value of PNA in NRH was significantly higher than that in NT ( p less than 0 . 001 ) and LRH ( p less than 0 . 001 ) . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
Of 103 borderline essential hypertensives below the age of 36 years , 11 ( 10 . 7 % ) showed low renin , 57 ( 55 . 4 % ) showed normal renin , and 35 ( 33 . 9 % ) showed high renin . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
This study investigated the changes in circadian rhythms of plasma renin activity ( PRA ) and plasma aldosterone ( PA ) which occur in essential mesor hypertensive women , increasing in age . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
No correlation was found between PRA , PAC and serum potassium in cord blood and in 2 to 6 day old infants , but there was a significant correlation between the parameters ( r = 0 . 72 and p less than 0 . 02 ) in 12 to 22 day old infants , indicating that at this age , as in healthy adults , the renin angiotensin system and serum potassium seem to be the major stimuli for aldosterone secretion . . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
We measured plasma renin activity in three groups of female psychiatric inpatients over the age of 50 : a TD group with high plasma DBH activity , a TD group with low plasma DBH activity , and a non TD group . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
Following overnight fast , mean plasma glucose was identical ( 10 patients and normal subjects approximately matched per age and sex ) ; plasma insulin , potassium and renin levels were lower and plasma aldosterone higher in the patients . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
Differences in renin activity and differences in aldosterone renin ratio could not be explained by differences in age , duration of hypertension and sex ratios . ^^^ These differences and the difference in renin activity between patients with high and patients with medium renin essential hypertension could not be explained by differences in age and / or sex ratio between the two subgroups . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
Renin angiotensin aldosterone system with regard to age ] . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
Plasma renin activity ( PRA ) and aldosterone concentration ( PA ) were measured in 20 healthy infants from 1 to 12 months of age during normal ( 3 . 03 mmol / kg / d ) and high ( 5 . 20 mmol / kg / d ) potassium intake . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
In 112 patients with essential hypertension ( HTA ) , free of any therapeutic and receiving the standard ward , a significant inverse relationship was found between age and plasma renin activity ( PRA ) and plasma aldosterone ( PA ) , measured in the supine and upright position . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
Plasma prolactin in normal and hypertensive subjects : relationships with age , posture , blood pressure , catecholamines , and renin . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
The results indicate that the renin angiotensin system can not be stimulated by furosemide under 106 days of gestation ; the response after 110 days increases with gestational age . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
Plasma renin , aldosterone , and dopamine beta hydroxylase activity in hypertensive patients over 70 years of age ( author ' s transl ) ] . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
Normal integrated concentration of aldosterone and plasma renin activity : effect of age . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
Renin activity in the blood plasma of healthy persons and in hypertension patients depending on age ] . ^^^ The early activation of the renin angiotensin system in the late stages of hypertensive disease should determine specified pathogenetic treatment of this disease in old age . . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
In comparison with group 1 , group 2 was characterized by : ( 1 ) similar values for age , blood pressure , inulin clearance and extracellular fluid volume and ( 2 ) significantly but lower values ( p less than 0 . 001 ) for plasma renin activity with maintenance of the relationship between extracellular fluid volume and renin . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
No differences in renal cortical renin content were found between 2 , 4 , and 8 week olds , but plasma renin concentration was highest at 2 weeks and declined with age . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
After allowance for the decrease of plasma renin activity ( PRA ) with age , direct relationships were observed between PRA ( log values ) and the level of pressure and systolic variability ; plasma angiotensin 2 values did not correlate . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
Corticosteroid biosynthesis from 14C progesterone by the adrenal glands in vitro , 14C aldosterone metabolism by the liver , plasma aldosterone content , and also angiotensin 1 concentration and blood plasma renin activity were studied in Okamoto rats with spontaneous hypertension and in Wistar rats with normal blood pressure , 4 5 weeks of age . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
Plasma renin activity , aldosterone and dopamine beta hydroxylase activity as a function of age in normal children . ^^^ In 149 children between 6 days and 15 years of age , plasma renin activity ( PRA ) and aldosterone ( PA ) were measured by radioimmunoassay and plasma dopamine beta hydroxylase activity ( DBH ) by the method of Nagatsu . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
The effects of propranolol ( 100 mg / kg ) , atenolol ( 200 mg / kg ) and acebutolol ( 1000 mg / kg ) administered daily by gavage to spontaneously hypertensive rats ( SHRs ) from their 6th to 20th weeks of age were investigated on genetic hypertension development ( GHD ) and at regular intervals on heart rate ( HR ) , cardiac output ( CO ) , stroke volume ( SV ) , peripheral resistence ( PR ) , plasma renin concentration ( PRC ) and heart weight / body weight ratio ( HW / BW ) . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
Plasma and kidney renin activity ( PRA , KRA ) were determined in the spontaneously hypertensive ( SHR ) rats , the stroke resistant and prone substrains ( SHRSR , SHRSP ) from 5 to 30 weeks of age . ^^^ However , the activated renin angiotensin system in SHRSP rats in the course of malignant hypertension at 20 weeks of age and later , could participate in raising blood pressure above the levels of the SHR and SHRSR . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
Supine ( basal ) plasma renin activity ( PRA ) and mean arterial pressure ( MAP ) were determined in 564 essential hypertensives grouped by age and sex . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
Influence of age and sodium intake on plasma renin activity of normal subjects . ^^^ Supine and upright plasma renin activity ( PRA ) were measured 1 104 normal subjects ( age range 13 74 years , 71 males and 33 females ) on a constant diet of normal potassium ( 60 80 mEq / day ) and of varying but constant , sodium content ( range 10 260 mEq / day ) . ^^^ These data can explain the contrasting reports on the age influence on renin secretion . ^^^ Therefore , the decline of PRA with age may be explained by the decrease either of renin storage or of sympathetic nervous system activity on renin release . . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
The release of both active and acid activatable ( inactive ) , renin was determined in piglets ranging in age from 3 to 53 days . ^^^ Both isoproterenol and furosemide stimulated release of renin in all age animals while propranolol supressed renin release . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
Effect of age on active and inactive plasma renin levels in normal subjects and in patients with essential hypertension ( author ' s transl ) ] . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
Similarly , no significant difference was found in plasma renin activity , plasma aldosterone level and urinary aldosterone excretion between the neonates whose birth weight was small or appropriate for gestational age . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
Both in male ( n = 353 ) and in female patients ( n = 211 ) with essential hypertension supine ( basal ) plasma renin activity showed an age dependent significant decrease whereas plasma aldosterone remained almost unchanged in women or was even slightly increased with age in men . ^^^ On the other hand , middle aged men ( 35 50 years ) showed a positive relationship between renin and blood pressure whereas in females of the same age group no correlation between these two parameters was found . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
The similarity of duration of hypertension in both groups and the lack of correlation between age and plasma renin activity suggest that low renin hypertension is a separate entity rather than just a later phase of the same disease . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
The results showed that the high levels of renin and angiotensin 2 present in infancy remained above adult levels throughout the first decade of life but that there was a decline with age . ^^^ Boys less than 8 years old had lower plasma renin activity and angiotensin 2 levels than girls of a similar age ; this may be due to a relative substrate deficiency . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
Basal plasma renin activity and plasma aldosterone concentrations were low and did not change significantly with age . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
Renin and big renin ( cryorenin ) were measured in the plasma of 78 babies at birth , and studied in six newborn lambs 2 3 weeks of age in response to angiotensin 2 ( 0 . 25 microgram / kg per min ) infusion . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
Exchangeable body sodium , blood volume , plasma renin activity , norepinephrine or dopamine levels , and norepinephrine or epinephrine excretion rates were similar between 24 patients with borderline hypertension ( mean age 34 + / 4 ( SEM ) years and 22 normal subjects matched for age ; the patients had a slight increase in supine plasma epinephrine . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
Plasma renin activity ( PRA ) was determined in conscious piglets between 1 and 50 days of age before and after treatment with saralasin and indomethacin . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
Renin activity and total body potassium fell significantly with age in both groups . 4 . ^^^ The relationship between renin and total body potassium was no longer present when the effects of age were allowed for in a partial correlation . . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
In conclusion , an A 5 fistula provokes two different hemodynamic behaviours which are related to age , pressure values , myocardial performance , presence of a left ventricular hypertrophy , PVR variations , and renin and nor adrenalin blood levels . . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
Plasma renin activity ( PRA ) , aldosterone ( PA ) and dopamine beta hydroxylase activity ( DBH ) were measured in 49 subjects over 70 years of age , selected for normal or high blood pressure level . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
Five men and 8 women , 60 69 yr of age , and 4 men and 5 women , 17 37 yr of age , volunteered for this exploration of possible age related changes in circadian rhythm ( CR ) characteristics of radioimmunoassayable plasma renin ( PRA ) and aldosterone ( PA ) . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
Though absolutely normal , noradrenaline in high renin essential hypertension was significantly higher than in low renin essential hypertension ; it correlated neither with age nor blood pressure . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
Plasma noradrenaline , active and inactive plasma renin , cardiac index and total peripheral vascular resistance were studied in 41 subjects , initially aged 10 19 years , who were followed up for at least 2 years after a blood pressure reading of 140 and / or 90 mmHg or more ( initial hypertensives ) and in 41 normotensive control subjects selected from the same population and matched for age , sex and body mass index . 2 . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
Effect of age on active and inactive plasma renin in normal subjects and in patients with essential hypertension . ^^^ The effect of age on the levels of active and trypsin activatable inactive plasma renin was examined in 41 normal subjects and 54 patients with essential hypertension , during recumbency and after stimulation with furosemide and ambulation . ^^^ Active renin levels in supine subjects and patients decreased with age . ^^^ Inactive renin levels did not change with age in normal subjects , whereas in hypertensive patients they decreased with age . ^^^ Following stimulation with furosemide and ambulation , the levels of active renin increased but the responsiveness to stimulus decreased with age in both groups . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
A study was performed in 7 healthy full term newborn infants with mean birth weight of 3130 g ( range , 2650 2850 g ) and a mean gestational age of 38 . 8 weeks ( range , 37 41 weeks ) to investigate the postnatal changes of plasma renin activity ( PRA ) , plasma aldosterone concentration ( PA ) and urinary aldosterone excretion ( UAE ) in relation to electrolyte balance . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
The effect of age on active and cryoactivatable inactive plasma renin in normal subjects and patients with essential hypertension . ^^^ The effect of age on active and cryoactivatable inactive plasma renin levels was examined in 58 normal subjects and 58 patients with essential hypertension during recumbency and after stimulation with furosemide and ambulation . ^^^ Active renin levels declined with age in both supine subjects and patients . ^^^ Inactive renin levels did not change with age in normal subjects , while in hypertensive patients they decreased with age . ^^^ Following stimulation with furosemide and ambulation , the levels of active renin increased but its responsiveness to the stimulus decreased with age in both groups . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
Sodium , potassium and age : possible determinants of plasma renin activity and aldosterone during childhood ( age 4 16 ) . ^^^ The plasma renin activity ( PRA ) and plasma aldosterone ( PA ) decreased with age : r = 0 . 30 , P less than 0 . 05 for plasma renin activity and r = 0 . 33 , P less than 0 . 05 for plasma aldosterone . ^^^ Using the multivariance analysis , plotting the plasma renin activity against the two combined parameters ( 24 h urinary sodium excretion and age ) , no improvement was obtained ( r = 0 . 38 , P greater than 0 . 05 ) . ^^^ This finding suggests that during childhood , sodium rather than age has a major modulatory role on plasma renin activity . ^^^ With advancing age the plasma aldosterone showed a significant positive correlation coefficient with plasma renin activity ( r = 0 . 29 , P less than 0 . 05 ) . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
Age dependence of human plasma renin substrate . ^^^ Plasma renin substrate concentration was higher at the age of 3 days ( females : 2028 + / 551 , males : 1951 + / 565 micrograms AI / l , mean + / SD ) than in age group 0 15 years ( females : 1513 + / 555 , males : 1263 + / 392 micrograms AI / l ) . ^^^ Plasma renin substrate concentration at the age over 15 years ( females : 1780 + / 464 , males 1752 + / 321 micrograms AI / l ) was higher than in children 0 15 years . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
Systemic and renal haemodynamics , intravascular volume , circulating catecholamines and plasma renin activity were measured in 18 patients with established essential hypertension who were older than 60 years of age . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
Plasma aldosterone ( PA ) , plasma renin activity ( PRA ) , extracellular fluid volume ( EFV ) and hepatic blood flow were measured in forty four patients with sustained essential hypertension and compared with forty two normotensive controls of same age and sex . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
Plasma noradrenaline concentration in essential hypertension with particular references to age , plasma renin activity and spontaneous fall of blood pressure ( author ' s transl ) ] . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
Plasma renin ( PRA ) and aldosterone activities were measured in 29 obese children and in 48 controls of the same age . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
Age related differences in the stoichiometry of the renin angiotensinogen reaction in rat plasma . ^^^ In conclusion , although the catalytic properties of renin do not change with age , subtle differences in the stoichiometry of the reaction may have profound implications in determining compensatory mechanisms involved in renin dependent regulation of homeostasis in developing animals . . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
The cardiovascular pressor responsiveness to infused norepinephrine ( NE ) or angiotensin 2 ( AII ) as related to endogenous plasma NE or renin levels was assessed in 20 patients with mild parenchymal kidney disease ( plasma creatinine 2 . 20 + / 0 . 58 mg / dl , + / SEM ) and in 20 normal subjects approximately matched for sex and age . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
The age , degree of renal impairment , plasma renin activity , and number and dosage of antihypertensive medicines did not account for these differences in NE . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
An investigation into the renin angiotensin aldosterone system ( RAAS ) in patients of advanced age with ischaemic heart disease ( IHD ) and different degrees of atherosclerotic cardiosclerosis by means of radioimmunoassay , which was used to determine the renin activity and the aldosterone concentration in the plasma , showed that there is in IHD an activation of the above regulatory system even under the conditions of relative rest . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
The interrelationships among age , cardiovascular pressor reactivity to intravenously infused norepinephrine ( NE ) or angiotensin 2 , and endogenous plasma NE or renin ( PRA ) levels were evaluated 1 31 normal subjects and 37 patients with essential hypertension . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
Plasma renin activity ( PRA ) was measured in 10 of them , who developed `` pregnancy induced hypertension ' ' ( `` PIH ' ' ) and in 10 normal pregnant women , matched with the hypertensive patients for age , parity and body weight . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
Thus , too often in the past , research into antihypertensive drugs has ignored the importance of underlying plasma drug concentrations and has sought to attribute the variability in antihypertensive response to factors such as age and plasma renin activity . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
The mean values for age , weight , height , basal neutrophil and lymphocyte counts , basal values of cortisol and renin of patients , and sex distribution of group 1 patients ( open , n = 20 ) matched with those for group 2 ( laparoscopic , n = 20 ) , with the exception of age ( p < 0 . 05 ) . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
The SH ( + ) group did not differ significantly in terms of age , heart rate , blood count , plasma biochemistry , plasma renin activity , plasma aldosterone , routine urinalysis , or urinary electrolytes from patients who did not show hypertension [ SH ( ) group ] . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
Effects of age and length of service on the state of the renin angiotensin aldosterone system and prostaglandin synthesis in coal miners ] . ^^^ In this connection activity of renin angiotensin aldosterone system ( RAAS ) in the miners before and after the work appeared to depend on the age and the length of service , to reach the maximum at the age of 31 40 and at 11 15 years of the service . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
The transgenic TGR ( mRen 2 ) 27 rat , in which the Ren 2 mouse renin gene is transfected into the genome of the Sprague Dawley rat , develops severe hypertension at a young age that responds to inhibitors of angiotensin converting enzyme and to antagonists of the type 1 angiotensin 2 ( Ang 2 ) receptor . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
Plasma atrial natriuretic peptide ( ANP ) , plasma and 24 h urine catecholamines , plasma renin activity ( PRA ) , and serum aldosterone were studied in offspring of hypertensive and normotensive families [ n = 82 ; age 37 + / 7 years ( mean + / SD ) ] . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
However , the plasma renin activity of Beige rats increases with age , whereas that of DA rats decreases . ^^^ These results suggested that giant JG granule formation slightly increases renin release with age , but does not affect blood pressure . . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
Low renin patients ( n = 9 , age 42 + / 3 years ) were defined as those individuals in balance on a low NaCl intake ( 10 mmol NaCl / day for 1 week ) who had a plasma renin activity < 0 . 30 ng angiotensin I / l / s , in both the supine and the upright positions . ^^^ The remaining hypertensives ( n = 18 , age 41 + / 4 years ) were classified into the normal renin group . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
The renal renin mRNA level in sham operated SHR decreased significantly with increasing age , whereas in the Wistar rats the renal renin mRNA level did not change at any age and was not affected by renal denervation . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
METHODS : Systolic tail blood pressure , mean arterial blood pressure , pulse rate , heart mass , body mass and relative heart mass were determined for each rat in the age range 17 19 weeks , and DNA polymorphisms were examined for the guanylyl cyclase A ( GCA ) , angiotensin converting enzyme ( ACE ) and renin ( REN ) genes . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
A male patient with hyperplasia of the juxtaglomerular apparatus , hypokalemia , an associated increase in plasma renin activity and hyperaldosteronism without hypertension was diagnosed as having Bartter ' s syndrome at the age of three . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
The purpose of this investigation was to assess changes in plasma renin activity ( PRA ) and plasma aldosterone in response to prolonged orthostatic stimulation in 19 young men with MVPS when compared to age and sex matched 20 control subjects . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
The levels of estradiol and plasma renin activity correlated in the 45 patients before ( r = 0 . 48 , P = . 001 ) and after ( r = 0 . 46 , P = . 002 ) controlling for age . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
Plasma renin activity ( PRA ) was lower in elderly normotensive subjects and essential hypertensives ( EHT ) , and a significant negative correlation was found between PRA and age in both groups . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
Plasma renin activity was determined in hundred normal subjects of either sex ( M = 65 , F = 35 , age range 2 70 yr ) using Angiotensin 1 test kits . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
RESULTS : The concentration of total renin in serum was higher in PCOS women than in healthy women independently of BMI , age , or serum insulin . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
When hypertensive patients were divided into those without ( n = 39 ) and with insulin resistance ( n = 16 ) , as defined by an elevated value of the ratio of the area under the curve of the response of insulin and glucose , it appeared that both heart rate , end systolic wall stress to end systolic volume index ratio and afterload corrected fractional shortening were higher in patients with insulin resistance , whereas age , arterial pressure , left ventricular mass index , urinary electrolytes , and plasma renin activity were similar in the two groups . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
The positive response of peripheral renin plasma levels to a single dose of captopril was used as a criterion for selecting 36 patients between 4 and 15 years of age with renovascular hypertension . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
We studied the effects of head down tilt to 10 degrees for 30 minutes on plasma atrial natriuretic peptide and the renin aldosterone system in 8 preeclamptic pregnant women , 8 healthy pregnant women , and 11 nonpregnant women of fertile age . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
RESULTS : The RVH and PH groups were similar with respect to age , sex , body mass index , diabetes , smoking habits , serum triglycerides , cholesterol , and blood pressure values , and differed only in plasma renin activity ( 6 . 0 + / 1 . 7 ng AngI / ml / h in RVH vs . 1 . 4 + / 0 . 3 in PH , mean + / SEM , p = 0 . 008 ) . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
Predictors of favourable blood pressure outcome following revascularization are aetiological ( fibrous dysplasia rather than atheroma ) , historical ( young age , short duration of hypertension ) , physiological ( renal ischaemia confirmed by scintigraphy , lateralizing renal vein renin ratio ) and anatomical ( truncal rather than ostial or branch stenoses ) . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
MAIN OUTCOME MEASURES : To assess the within patient correlations among the blood pressure responses to each drug and explore the possible role of simple characteristics , such as the initial blood pressure , plasma renin concentration and age , in identifying the responders to a particular drug . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
Polymorphisms at the atrial natriuretic factor , antithrombin 3 , renin , angiotensinogen , neuropeptide Y Y 1 receptor , insulin , alpha 2 adrenoceptor , beta 1 adrenoceptor , growth hormone , low density lipoprotein receptor , insulin receptor and renal kallikrein gene loci were found to display similar allele frequencies in each age group of hypertensives , as well as in normotensive controls . 4 . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
Effects of age and sex on sodium chloride sensitivity : association with plasma renin activity . ^^^ The present study was undertaken in 87 Japanese inpatients with essential hypertension to investigate the interrelation among effects of age , sex and the renin angiotensin system on NaCl sensitivity . ^^^ In conclusion , NaCl sensitivity of blood pressure is independently associated with age and the inadequate suppression of the renin angiotensin system . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
Although the activity of the renin angiotensin system is known to decrease with age , the antihypertensive efficacy of angiotensin converting enzyme ( ACE ) inhibitors has been demonstrated in the elderly . ^^^ These results suggest that the activity of the renin angiotensin system in plasma declines with age , and that the extrarenal renin angiotensin system may play a role in hypertension in the elderly . . ^^^
Interacting proteins: P51606 and P00797	Pubmed	SVM Score :0.0
Peripheral plasma renin activity and plasma aldosterone activity increased at the age of 6 months , and ultimately reached the peak at 9 days after discontinuation of furosemide at the age of 7 months . ^^^ Peripheral plasma renin activity and plasma aldosterone activity were normalized at the age of 11 months . ^^^