| Interacting proteins: P42858 and P78352 |
Pubmed |
SVM Score :0.0 |
| NA |
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| Interacting proteins: P42858 and P78352 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P42858 and P78352 |
Pubmed |
SVM Score :0.0 |
| Expression of polyglutamine expanded huntingtin induced elevation of phosphorylated or activated Src and increased targeting of PSD 95 ( post synaptic density 95 ) and activated Src to cell surface membrane . ^^^ Expression of the mutated huntingtin also induced tyrosine phosphorylation of NR2B ( NMDA receptor 2B ) subunits , and co expression of PSD 95 enhanced the phosphorylation . ^^^ Taken together , our studies show that polyglutamine expanded huntingtin increases tyrosine phosphorylation of NMDA receptors via PSD 95 and Src , and increased tyrosine phosphorylation may contribute to the sensitization of the receptors mediated by polyglutamine expanded huntingtin . . ^^^ |
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| Interacting proteins: P42858 and P78352 |
Pubmed |
SVM Score :0.0 |
| The higher expression levels of these molecules in nNOS IN when compared with MSN together with an association of nNOS , NR2D and HAP 1 in a protein complex with PSD 95 suggest that these proteins may be involved in protective pathways that contribute to the resistance of this interneuron population to neurodegeneration in HD . . ^^^ |
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| Interacting proteins: P42858 and P78352 |
Pubmed |
SVM Score :0.0 |
| HIP 14 shows remarkable substrate specificity for neuronal proteins , including SNAP 25 , PSD 95 , GAD 65 , synaptotagmin 1 , and htt . ^^^ |
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