| Interacting proteins: P42858 and P63165 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P42858 and P63165 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P42858 and P63165 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P42858 and P63165 |
Pubmed |
SVM Score :0.0 |
| Plasma PCI levels in these patients before HD were significantly decreased . ^^^ Plasma TAT , PPIC , and tissue type plasminogen activator levels were significantly higher before HD than after 1 hour HD and at the end of HD , while the changes in plasma protein C antigen , protein S antigen , PCI antigen , APC PCI complex , and APC alpha 1AT complex were not significant after 1 hour of HD or at the end of HD compared to levels before HD . ^^^ |
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| Interacting proteins: P42858 and P63165 |
Pubmed |
SVM Score :0.0 |
| Plasma levels of activated protein C ( APC ) protein C inhibitor ( PCI ) were significantly increased in patients with disseminated intravascular coagulation ( DIC ) , thrombotic thrombocytopenic purpura ( TTP ) , acute myocardial infarction ( AMI ) , pulmonary embolism ( PE ) , or deep vein thrombosis ( DVT ) and in patients undergoing hemodialysis ( HD ) . ^^^ Plasma levels of PCI were significantly decreased in patients with DIC , non DIC , or TTP and in those undergoing HD . ^^^ The positive rate of APC PCI complex was higher than 90 % with DIC , TTP , AMI , PE , and it was higher than 60 % with DVT and HD . ^^^ |
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| Interacting proteins: P42858 and P63165 |
Pubmed |
SVM Score :0.0 |
| Therefore , in this study the effects of human recombinant EPO and 1 alpha D 3 treatments on lymphocyte PC 1 expression in patients with end stage renal failure on haemodialysis ( HD ) were investigated . ^^^ METHODS : Lymphocyte basal , concanavalin A ( Con A ) , and phorbol 12 myristate 13 acetate ( PMA ) stimulated PC 1 activity were investigated in HD patients before and after a two month treatment with subcutaneous EPO ( 15 patients , 2000 3000 U thrice weekly ) or oral 1 alpha D 3 ( 14 patients , 2 mug thrice weekly ) . ^^^ Basal lymphocyte PC 1 activity in HD patients was found to be significantly increased ( P < 0 . 005 ) over the level in healthy controls . ^^^ Lymphocyte Con A and PMA stimulated PC 1 activity in patients on HD was found to be slightly increased over the level in healthy controls , but significantly reduced ( P < 0 . 005 and 0 . 05 , respectively ) after the EPO treatment . ^^^ CONCLUSION : An increased lymphocyte PC 1 activity over control was found in HD patients . ^^^ |
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