Interacting proteins: P42858 and P35520 |
Pubmed |
SVM Score :0.53028714 |
Huntingtin interacts with cystathionine beta synthase . 0.53028714^^^ |
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Interacting proteins: P42858 and P35520 |
Pubmed |
SVM Score :0.0 |
Because the protein Huntingtin interacts with the homocysteine metabolism modulating enzyme cystathionine beta synthase , we hypothesize that homocysteine promotes neurodegeneration in HD . . ^^^ |
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Interacting proteins: P42858 and P35520 |
Pubmed |
SVM Score :0.0 |
Cystathionine beta synthase was not relocalized in HD brain , but the N CoR was excluded from neuronal nuclei in HD brain , and a further protein that exists in the same repression complex , mSin 3 , was similarly excluded . ^^^ |
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Interacting proteins: P42858 and P35520 |
Pubmed |
SVM Score :0.0 |
Objective of this study was to analyze the impact of CAG repeats , polymorphisms of various homocysteine metabolizing enzymes , like CBS , Methyltetrahydrofolate Reductase ( MTHTR ) , Methionine Synthase Reductase ( MSR ) and methionine synthase ( MS ) on HD onset in 171 patients . ^^^ |
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Interacting proteins: P42858 and P35520 |
Pubmed |
SVM Score :0.0 |
Because mutated Huntington protein influences Hcy metabolism by modulating cystathionine beta synthase activity , Hcy could represent a biological marker of neurodegeneration and could explain the leading role of cardiovascular and cerebrovascular diseases as causes of death in HD . ^^^ |
|
Interacting proteins: P42858 and P35520 |
Pubmed |
SVM Score :0.0 |
NA |
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