| Interacting proteins: P17535 and P41182 |
Pubmed |
SVM Score :0.0 |
| We found that the zinc finger region of BCL 6 interacts with c Jun , JunB , and JunD proteins but does not bind c Fos or Fra 2 proteins . ^^^ |
|
| Interacting proteins: P17535 and P41182 |
Pubmed |
SVM Score :0.0 |
| JunD / AP 1 and STAT 3 are the major enhancer molecules for high Bcl 6 expression in germinal center B cells . ^^^ Activated STAT factors ( STATs ) , especially activated STAT 3 , also bound to the silencer elements in GC B cells and competed with Bcl 6 for the binding , suggesting that JunD / AP 1 and activated STATs drive high Bcl 6 expression in GC B cells . ^^^ Since stimulation of splenic B cells with IL 4 or IL 21 induced high Bcl 6 expression with induction of junD and activation of STATs , these cytokines may be inducers for its high expression in GC B cells . ^^^ |
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