Pubmed abstracts for Protein-Protein Interaction search result :


Interacting proteins: P62995 and P38159 Pubmed SVM Score :0.0
RBMY , a probable human spermatogenesis factor , and other hnRNP G proteins interact with Tra2beta and affect splicing . ^^^ We show here that RBM , hnRNP G and a novel testis specific relative , termed hnRNP G T , interact with Tra2beta , an activator of pre mRNA splicing that is ubiquitous but highly expressed in testis . ^^^ Endogenous hnRNP G and Tra2beta proteins are associated in HeLa nuclear extracts . ^^^ We conclude that the hnRNP G family of proteins is involved in pre mRNA splicing and infer that RBM may be involved in Tra2beta dependent splicing in spermatocytes . . ^^^
Interacting proteins: P62995 and P38159 Pubmed SVM Score :0.0
HnRNP G and Tra2beta : opposite effects on splicing matched by antagonism in RNA binding . ^^^ Since the ratio of hnRNP G to Tra2beta mRNA in humans is higher in skeletal muscle than in heart muscle , we propose that the hnRNP G / Tra2beta ratio contributes to the cellular splicing preferences and that the higher proportion of hnRNP G in skeletal muscle plays a role in preventing the incorporation of the pseudo exon and thus in preventing skeletal muscle dystrophy . . ^^^