RBMY , a probable human spermatogenesis factor , and other hnRNP G proteins interact with Tra2beta and affect splicing . ^^^ We show here that RBM , hnRNP G and a novel testis specific relative , termed hnRNP G T , interact with Tra2beta , an activator of pre mRNA splicing that is ubiquitous but highly expressed in testis . ^^^ Endogenous hnRNP G and Tra2beta proteins are associated in HeLa nuclear extracts . ^^^ We conclude that the hnRNP G family of proteins is involved in pre mRNA splicing and infer that RBM may be involved in Tra2beta dependent splicing in spermatocytes . . ^^^ |