| Interacting proteins: Q04912 and P31749 |
Pubmed |
SVM Score :0.0 |
| AKT kinase is a component of a separate branch of the RON / PI3 K pathway that mediates the MSP anti apoptotic effect on epithelial cells . ^^^ |
|
| Interacting proteins: Q04912 and P31749 |
Pubmed |
SVM Score :0.0 |
| RON liberated from the association with HYAL 2 becomes functionally active and consequently activates the Akt and mitogen activated protein kinase pathways leading to oncogenic transformation of immortalized human bronchial epithelial cells . ^^^ |
|
| Interacting proteins: Q04912 and P31749 |
Pubmed |
SVM Score :0.0 |
| RON activation induces the phosphorylation of Gab 1 , mitogen activated protein kinase ( MAPK ) , and protein kinase B ( PKB ) but not of signal transducer and activator of transcription 5 ( Stat 5 ) . ^^^ |
|
| Interacting proteins: Q04912 and P31749 |
Pubmed |
SVM Score :0.0 |
| Ablation of Ron signaling resulted in partial defects in MAPK and Akt signaling that may account for the decreased papilloma growth in the TK ( / ) Tg . ^^^ |
|
| Interacting proteins: Q04912 and P31749 |
Pubmed |
SVM Score :0.0 |
| In particular , the cytoplasmic tail of Env is required for transformation , the PI3K / Akt pathway is activated , expression of RON ( which is not normally expressed in MDCK cells ) does not affect transformation , and canine Hyal 2 appears uninvolved . ^^^ |
|
| Interacting proteins: Q04912 and P31749 |
Pubmed |
SVM Score :0.0 |
| Biochemical analyses on mammary tumor lysates showed that whereas both the pMT expressing TK+ / + and TK / tumors have increased Ron expression compared with normal mammary glands , the pMT expressing TK / tumors have deficits in mitogen activated protein kinase and AKT activation . ^^^ |
|
| Interacting proteins: Q04912 and P31749 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q04912 and P31749 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q04912 and P31749 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q04912 and P31749 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q04912 and P31749 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q04912 and P31749 |
Pubmed |
SVM Score :0.0 |
| NA |
|