| Interacting proteins: P13727 and P31749 |
Pubmed |
SVM Score :0.0 |
| The SH 2 like and catalytic domains of Akt were expressed in E . coli as fusions to the carboxy terminus of the Maltose binding protein ( MBP ) . ^^^ |
|
| Interacting proteins: P13727 and P31749 |
Pubmed |
SVM Score :0.0 |
| Measurement of Akt phosphorylation at Ser ( 473 ) and Thr ( 308 ) confirmed that MBP stimulated PI3K activity and also demonstrated indirectly activation of phosphoinositide dependent kinase 1 by MBP . ^^^ Genistein and the Src kinase family inhibitor , 4 amino 5 ( 4 methyphenyl ) 7 ( t butyl ) pyrazolo [ 3 , 4 d ] pyrimidine , inhibited MBP stimulated phosphorylation of Akt . 4 Amino 5 ( 4 methyphenyl ) 7 ( t butyl ) pyrazolo [ 3 , 4 d ] pyrimidine also inhibited MBP stimulated O ( 2 ) ( ) production . ^^^ |
|
| Interacting proteins: P13727 and P31749 |
Pubmed |
SVM Score :0.0 |
| Both MBP 1 and EDN induced phosphorylation of Akt , but with divergent time courses and intensities , and survival was independent of Akt . ^^^ |
|
| Interacting proteins: P13727 and P31749 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P13727 and P31749 |
Pubmed |
SVM Score :0.0 |
| NA |
|