| Interacting proteins: O14492 and P31749 |
Pubmed |
SVM Score :0.64664685 |
| Taken together , this study identifies APS as a novel physiological substrate for PKB and the first serine phosphorylation site on APS . 0.64664685^^^ In this study , we have identified APS as a novel substrate for protein kinase B / Akt using an antibody that exhibits insulin dependent immunoreactivity with a phosphospecific antibody raised against the protein kinase B substrate consensus sequence RXRXX ( pS / pT ) and a phosphospecific antibody that recognizes serine 21 / 9 of glycogen synthase kinase 3alpha / beta . 0.52731735^^^ |
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| Interacting proteins: O14492 and P31749 |
Pubmed |
SVM Score :0.0 |
| T APS cells , Akt phosphorylation is observed earlier than in CHO . ^^^ Both enhance insulin stimulated Akt activation but APS seems to cause greater activation . ^^^ |
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| Interacting proteins: O14492 and P31749 |
Pubmed |
SVM Score :0.0 |
| In control cells that lack APS , following insulin stimulation , extracellular signal regulated kinase ( ERK ) and Akt kinase reach maximal activation and then decline to basal levels by 60 min . ^^^ In contrast , in APS and SH 2 B expressing cells , ERK and Akt kinase activation remains at peak levels at 60 min . ^^^ |
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| Interacting proteins: O14492 and P31749 |
Pubmed |
SVM Score :0.0 |
| However , overexpression of wild type or dominant negative APS in 3T3L1 adipocytes did not affect insulin receptor numbers , phosphorylations of insulin receptor , insulin receptor substrate 1 , or Akt and mitogen activated protein kinase . ^^^ |
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| Interacting proteins: O14492 and P31749 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: O14492 and P31749 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: O14492 and P31749 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: O14492 and P31749 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: O14492 and P31749 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: O14492 and P31749 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: O14492 and P31749 |
Pubmed |
SVM Score :0.0 |
| NA |
|