| Interacting proteins: P30988 and O60894 |
Pubmed |
SVM Score :0.0 |
| In conclusion , RAMP 1 and 3 decrease calcitonin receptor expression in RAEC transfected with hCTR 2 encoding cDNA and simultanously reveal an amylin receptor . . ^^^ |
|
| Interacting proteins: P30988 and O60894 |
Pubmed |
SVM Score :0.0 |
| Cotransfection with calcitonin receptor ( CTR ) I 1 induced cell surface expression of RAMP 1 . ^^^ |
|
| Interacting proteins: P30988 and O60894 |
Pubmed |
SVM Score :0.0 |
| Thus , RAMP 1 or RAMP 3 can modify the calcitonin receptor ( CTR ) to also function as a high affinity amylin receptor like phenotype . ^^^ |
|
| Interacting proteins: P30988 and O60894 |
Pubmed |
SVM Score :0.0 |
| Furthermore , RAMP proteins have also been shown to govern the pharmacology of the calcitonin receptor , which in association with RAMP 1 or RAMP 3 , binds amylin with high affinity . ^^^ |
|
| Interacting proteins: P30988 and O60894 |
Pubmed |
SVM Score :0.0 |
| The initially orphan calcitonin receptor like receptor ( CRLR ) was identified as a CGRP receptor when coexpressed with RAMP 1 . ^^^ An amylin / CGRP receptor was recognized when a calcitonin receptor ( CTR ) was coexpressed with RAMP 1 . ^^^ |
|
| Interacting proteins: P30988 and O60894 |
Pubmed |
SVM Score :0.0 |
| CGRP receptor belongs to the calcitonin receptor like receptor ( CRLR ) family of G protein coupled receptors and has been shown to require a single transmembrane domain protein called receptor activity modifying protein 1 ( RAMP 1 ) for its functional expression as well as activity . ^^^ |
|
| Interacting proteins: P30988 and O60894 |
Pubmed |
SVM Score :0.0 |
| The calcitonin like receptor ( CLR ) and the calcitonin receptor ( CTR ) interact with receptor activity modifying protein 1 ( RAMP 1 ) at the cell surface to form heterodimeric receptor complexes . ^^^ |
|
| Interacting proteins: P30988 and O60894 |
Pubmed |
SVM Score :0.0 |
| The CTa ( shorter form ) calcitonin receptor , dimerized with RAMP 1 [ amylin 1 ( a ) receptor ] , appears to represent binding sites at the nucleus accumbens and the subfornical organ . ^^^ |
|
| Interacting proteins: P30988 and O60894 |
Pubmed |
SVM Score :0.0 |
| RAMP 1 and 3 which are co expressed with CTR revealed two amylin receptor isotypes . ^^^ |
|
| Interacting proteins: P30988 and O60894 |
Pubmed |
SVM Score :0.0 |
| The same CTR is a CGRP / amylin or an amylin receptor upon co expression with RAMP 1 or 3 , respectively . ^^^ |
|
| Interacting proteins: P30988 and O60894 |
Pubmed |
SVM Score :0.0 |
| An amylin / CGRP receptor is revealed when CTR is co expressed with RAMP 1 . ^^^ CTR RAMP 1 , antagonized preferentially by salmon CT ( 8 32 ) and not by CGRP ( 8 37 ) , and CRLR RAMP 1 , antagonized by CGRP ( 8 37 ) , are two CGRP receptor isotypes . ^^^ Thus amylin and CGRP interact specifically with heterodimeric complexes between CTR and RAMP 1 or RAMP 3 , and CGRP and AM interact with complexes between CRLR and RAMP 1 , RAMP 2 or RAMP3 . . ^^^ |
|
| Interacting proteins: P30988 and O60894 |
Pubmed |
SVM Score :0.0 |
| The specificity of CRLR was clearly determined by the expression of RAMPs ; RAMP 1 converted CRLR to CGRP receptor , while RAMP 2 and RAMP 3 converted it to AM receptor , but the affinity of CTR for AMY was not increased by the expression of any known RAMPs . ^^^ |
|
| Interacting proteins: P30988 and O60894 |
Pubmed |
SVM Score :0.0 |
| Osteoclast like cells expressed CT receptor ( CTR ) , CT receptor like receptor ( CRLR ) and RAMP 2 , but did not express RAMP 1 or RAMP 3 . ^^^ |
|
| Interacting proteins: P30988 and O60894 |
Pubmed |
SVM Score :0.0 |
| CTR has been reported to act as an amylin receptor when heterodimerized with receptor activity modifying protein 1 ( RAMP 1 ) or RAMP 3 . mRNA expression of RAMP 1 and RAMP 3 in mammary tissue decreased during pregnancy and lactation , and amylin mRNA was undetectable , suggesting that up regulated CTR in lactating mammary tissues binds CT rather than amylin . ^^^ |
|
| Interacting proteins: P30988 and O60894 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P30988 and O60894 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P30988 and O60894 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P30988 and O60894 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P30988 and O60894 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P30988 and O60894 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P30988 and O60894 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P30988 and O60894 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P30988 and O60894 |
Pubmed |
SVM Score :0.0 |
| NA |
|