| Interacting proteins: P23560 and P29474 |
Pubmed |
SVM Score :0.0 |
| We report here that motor neurons constitutively express endothelial NOS that helps support the survival of motor neurons cultured with brain derived neurotrophic factor ( BDNF ) by activating the nitric oxide dependent soluble guanylate cyclase . ^^^ |
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| Interacting proteins: P23560 and P29474 |
Pubmed |
SVM Score :0.0 |
| ELISAs showed that eNOS / mice have decreased brain derived neurotrophic factor ( BDNF ) expression but not VEGF and basic fibroblast growth factor in the ischemic brain compared with wild type mice . ^^^ BDNF treatment of SVZ cells derived from eNOS / mice restored the decreased neurosphere formation , proliferation , neurite outgrowth , and telomerase activity in cultured eNOS ( / ) SVZ neurospheres . ^^^ These data indicate that eNOS is not only a downstream mediator for VEGF and angiogenesis but also regulates BDNF expression in the ischemic brain and influences progenitor cell proliferation , neuronal migration , and neurite outgrowth and affects functional recovery after stroke . . ^^^ |
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| Interacting proteins: P23560 and P29474 |
Pubmed |
SVM Score :0.0 |
| NA |
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