Exposing isolated rat skeletal muscle to 5 aminoimidazole 4 carboxamide 1 beta D ribofuranoside [ AICAR , a pharmacological activator of AMP activated protein kinase ( AMPK ) ] plus serum leads to a subsequent increase in insulin stimulated glucose transport ( Fisher JS , Gao J , Han DH , Holloszy JO , and Nolte LA . ^^^