| Repression of Dlk 1 requires HDAC 3 deacetylase activity , which is recruited to the endogenous Dlk 1 promoter where it interacts with KLF 6 . ^^^ Our studies identify the interaction between HDAC 3 and KLF 6 as a potential mechanism underlying human adipogenesis , and highlight the role of KLF 6 as a multifunctional transcriptional regulator capable of mediating adipocyte differentiation through gene repression . . ^^^ |