Interacting proteins: O15379 and P05412 |
Pubmed |
SVM Score :0.0 |
NA |
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Interacting proteins: O15379 and P05412 |
Pubmed |
SVM Score :0.0 |
NA |
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Interacting proteins: O15379 and P05412 |
Pubmed |
SVM Score :0.0 |
HDAC 3 but not HDAC 1 or HDAC 2 was required for AP 1 mediated stimulation of c jun expression . ^^^ |
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Interacting proteins: O15379 and P05412 |
Pubmed |
SVM Score :0.0 |
JDP 2 , a repressor of AP 1 , recruits a histone deacetylase 3 complex to inhibit the retinoic acid induced differentiation of F 9 cells . ^^^ We show here that the overexpression of Jun dimerization protein 2 ( JDP 2 ) , a repressor of AP 1 , inhibits the transactivation of the c jun gene by ATF 2 and p 300 by recruitment of the histone deacetylase 3 ( HDAC 3 ) complex , thereby repressing the RA induced transcription of the c jun gene and inhibiting the RA mediated differentiation of F 9 cells . ^^^ |
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Interacting proteins: O15379 and P05412 |
Pubmed |
SVM Score :0.0 |
We show that c Jun phosphorylation mediates dissociation of an inhibitory complex , which is associated with histone deacetylase 3 ( HDAC 3 ) . ^^^ |
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Interacting proteins: O15379 and P05412 |
Pubmed |
SVM Score :0.0 |
Studying the mechanisms controlling c Jun activity we found that its transcription activation function is actively repressed by a presumably multimeric repressor complex that includes histone deacetylase 3 as a critical subunit . ^^^ |
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Interacting proteins: O15379 and P05412 |
Pubmed |
SVM Score :0.0 |
More importantly , we show here that the N CoR HDAC 3 complex inhibits JNK activation through the associated GPS 2 subunit and thus could potentially provide an alternative mechanism for hormone mediated antagonism of AP 1 function . . ^^^ |
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