| Interacting proteins: O75446 and O15379 |
Pubmed |
SVM Score :0.0 |
| Moreover , we describe a SAP 30 homolog in yeast that is functionally related to Sin 3 and the histone deacetylase Rpd 3 . ^^^ |
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| Interacting proteins: O75446 and O15379 |
Pubmed |
SVM Score :0.0 |
| Here we demonstrate that Sin 3 , Rpd 3 , and Sap 30 , a novel component of the Sin 3 Rpd3 complex , affect silencing not only at the HMR and telomeric loci , but also at the rDNA locus . ^^^ |
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| Interacting proteins: O75446 and O15379 |
Pubmed |
SVM Score :0.0 |
| The transcription profile of rpd 3 is similar to the profiles of sin 3 , sap 30 , ume 6 , and TSA treated wild type yeast . ^^^ |
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| Interacting proteins: O75446 and O15379 |
Pubmed |
SVM Score :0.0 |
| The Rpd 3 histone deacetylase ( HDAC ) functions in a large complex containing many proteins including Sin 3 and Sap 30 . ^^^ Previous evidence indicates that the pho 23 , rpd 3 , sin 3 , and sap 30 mutants exhibit similar defects in PHO 5 regulation . ^^^ We report that pho 23 mutants like rpd 3 , sin 3 , and sap 30 are hypersensitive to cycloheximide and heat shock and exhibit enhanced silencing of rDNA , telomeric , and HMR loci , suggesting that these genes are functionally related . ^^^ Our results demonstrate that Myc Pho 23 co immunoprecipitates with HA Rpd 3 and HA Sap 30 . ^^^ Furthermore , similar levels of HDAC activity were detected in immunoprecipitates of HA Pho 23 , HA Rpd 3 , or HA Sap 30 . ^^^ |
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| Interacting proteins: O75446 and O15379 |
Pubmed |
SVM Score :0.0 |
| In addition to RPD 3 , repression by pRB in yeast requires MSI 1 , an ortholog of RbAp 48 , but not SIN 3 or SAP 30 . ^^^ |
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| Interacting proteins: O75446 and O15379 |
Pubmed |
SVM Score :0.0 |
| The Rpd 3 histone deacetylase complex contains several previously characterized proteins , including Rpd 3 , Sin 3 , Sds 3 , Sap 30 , and Pho 23 . ^^^ |
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| Interacting proteins: O75446 and O15379 |
Pubmed |
SVM Score :0.0 |
| These included Rpd 3 , Sds 3 , Pho 23 , Dep 1 , Rxt 2 , Sin 3 , Ash 1 , Ume 1 , Sap 30 , Cti 6 , Rxt 3 and Ume 6 . ^^^ |
|
| Interacting proteins: O75446 and O15379 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: O75446 and O15379 |
Pubmed |
SVM Score :0.0 |
| NA |
|